The Good Virus The Amazing Story And Forgotten Promise Of The Phage

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The Good Virus: The Amazing Story and Forgotten Promise of the Phage

Author : Tom Ireland
Publisher : W. W. Norton & Company
ISBN 13 : 1324050845
Total Pages : 307 pages
Book Rating : 4.3/5 (24 download)

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Book Synopsis The Good Virus: The Amazing Story and Forgotten Promise of the Phage by : Tom Ireland

Download or read book The Good Virus: The Amazing Story and Forgotten Promise of the Phage written by Tom Ireland and published by W. W. Norton & Company. This book was released on 2023-08-15 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Editors’ Choice “A deft narrative that is rich and approachable.” —Alex Johnson, New York Times Book Review How a mysterious, super-powerful—yet long-neglected—microbe rules our world and can rescue our health in the age of antibiotic resistance. At every moment, within our bodies and all around us, trillions of microscopic combatants are waging a war that shapes our health and life on Earth. Countless times per second, viruses known as phages attack and destroy bacteria while leaving all other life forms, including us, unscathed. Vastly outnumbering the viruses that do us harm, phages power ecosystems, drive evolutionary innovation, and harbor a remarkable capacity to heal life-threatening infections when conventional antibiotics fail. Yet most of us have never heard of them, thinking of viruses only as enemies to be feared. The Good Virus prompts us to reconsider, and to discover, how these viruses could save countless lives if we can learn to harness their extraordinary abilities. Taking us inside the ongoing quest to use phages’ powers for good, Tom Ireland introduces us to the brilliant, often eccentric, scientists who have fought to realize phages’ potential in the face of doubt and political intrigue. We meet the renegade French-Canadian scientist who discovered phages and pioneered their use as medicine over a century ago, leading them to be hailed as the world’s first genuine antibiotic years before penicillin. We learn why, in some pockets of the former Soviet Union, drinking a vial of phages remains as common as taking an over-the-counter drug. We follow the intrepid scientists and doctors now racing to make “phage therapy” work worldwide as the threat of antibiotic-resistant bacteria grows ever more urgent—even as other researchers uncover how phages bolster our everyday immunity, help generate the oxygen we breathe, and furnish the origins for breakthrough technologies like CRISPR. Unveiling the hidden rulers of the microbial world and celebrating the surprising power of viruses to heal, not harm, The Good Virus forever changes how we see nature’s most maligned life forms.

The Good Virus

Author : Tom Ireland
Publisher : Hachette UK
ISBN 13 : 1529365260
Total Pages : 479 pages
Book Rating : 4.5/5 (293 download)

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Book Synopsis The Good Virus by : Tom Ireland

Download or read book The Good Virus written by Tom Ireland and published by Hachette UK. This book was released on 2023-06-29 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: CHOSEN AS A BOOK OF THE YEAR 2023 BY WATERSTONES AND THE TIMES The viruses that do us harm are vastly outnumbered by viruses that can actually save lives. These good viruses are called 'phages', and they are the most abundant life form on Earth. The Good Virus reveals how these weird and wonderful microbes shape our health, support our ecosystems and could be the future of medicine.

The Perfect Predator

Author : Steffanie Strathdee
Publisher : Hachette Books
ISBN 13 : 0316418072
Total Pages : 346 pages
Book Rating : 4.3/5 (164 download)

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Book Synopsis The Perfect Predator by : Steffanie Strathdee

Download or read book The Perfect Predator written by Steffanie Strathdee and published by Hachette Books. This book was released on 2019-02-26 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

Félix d`Herelle and the Origins of Molecular Biology

Author : William C. Summers
Publisher : Yale University Press
ISBN 13 : 9780300174250
Total Pages : 272 pages
Book Rating : 4.1/5 (742 download)

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Book Synopsis Félix d`Herelle and the Origins of Molecular Biology by : William C. Summers

Download or read book Félix d`Herelle and the Origins of Molecular Biology written by William C. Summers and published by Yale University Press. This book was released on 1999-06-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A self-taught scientist determined to bring science out of the laboratory and into the practical arena, French-Canadian Felix d’Herelle (1873-1949) made history in two different fields of biology. Not only was he first to demonstrate the use and application of bacteria for biological control of insect pests, he also became a seminal figure in the history of molecular biology. This engaging book is the first full biography of d’Herelle, a complex figure who emulated Louis Pasteur and influenced the course of twentieth-century biology, yet remained a controversial outsider to the scientific community. Drawing on family papers, archival sources, interviews, and d’Herelle’s published and unpublished writings, Dr. William C. Summers tells the fascinating story of the scientist’s life and the work that took him around the globe. In 1917, d’Herelle published the first paper describing the phenomenon of the bacteriophage and its biological nature. A series of more than 110 articles and 6 major books followed, in which d’Herelle established the foundation for the later work of the Phage Group in molecular biology. Yet d’Herelle sometimes inspired animosity in others--he was drummed out of the Pasteur Institute, he held only one brief permanent position in the scientific establishment (at Yale University from 1928 to 1933), and he was bewildered by the social nuances of the world of international science. His story is more than the biography of a single brilliant scientist; it is also a fascinating chapter in the history of biology.

Life in Our Phage World

Author : Forest Rohwer
Publisher :
ISBN 13 : 9780990494300
Total Pages : 404 pages
Book Rating : 4.4/5 (943 download)

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Book Synopsis Life in Our Phage World by : Forest Rohwer

Download or read book Life in Our Phage World written by Forest Rohwer and published by . This book was released on 2014-12-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: We share the Earth with more than 10,000,000,000,000,000,000,000,000,000,000 phages. Everywhere they thrive, from well-fed guts to near-boiling acidic springs, from cryoconite holes to endolithic fissures. They travel from one microbial host to the next as virions, their genetic weapons packaged inside a protective protein shell. If you could lay all of these nanoscopic phage virions side-by-side, the line-up would stretch over 42 million light years. Through their daily shenanigans they kill or collaborate with their microbial hosts to spur microbial evolution and maintain ecosystem functioning. We have learned much about them since their discovery by Frederick Twort a century ago. They also taught us that DNA, not protein, is the hereditary material, unraveled the triplet genetic code, and offered their enzymes as indispensible tools for the molecular biology revolution. More contributions will be forthcoming since the vast majority of phages await discovery. Phage genomes harbor the world's largest cache of unexplored genetic diversity, and we now have the equipment needed to go prospecting. Although there are field guides to birds, insects, wild flowers, even Bacteria, there was no such handbook to guide the phage explorer. Forest Rohwer decided to correct this oversight, for novice and expert alike, and thus was born Life in Our Phage World. A diverse collection of 30 phages are featured. Each phage is characterized by its distinctive traits, including details about its genome, habitat, lifestyle, global range, and close relatives. The beauty of its intricate virion is captured in a pen-and-ink portrait by artist Benjamin Darby. Each phage also stars in a carefully researched action story relating how that phage encounters, exploits, kills, or otherwise manipulates its host. These behaviors are imaginatively illustrated by fine artist Leah L. Pantea. Eight researchers that work closely with phages also relate their experiences as inhabitants of the phage world. Rohwer has years of first-hand experience with the phage multitudes in ecosystems ranging from coral reefs to the human lung to arctic waters. He pioneered the key metagenomic methods now widely used to catalog and characterize Earth's microbial and viral life. Despite research advances, most people, many scientists included, remain unaware of the ongoing drama in our phage world. In anticipation of 2015, the centennial of phage discovery, Forest assembled a cadre of writers, artists, scientists, and a cartographer and set them to work. The result? This alluring field guide-a feast for the imagination and a celebration of phage diversity."

Viruses Vs. Superbugs

Author : T. Häusler
Publisher : Springer
ISBN 13 : 0230552285
Total Pages : 307 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Viruses Vs. Superbugs by : T. Häusler

Download or read book Viruses Vs. Superbugs written by T. Häusler and published by Springer. This book was released on 2016-05-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.

Miracle Cure

Author : William Rosen
Publisher : Penguin
ISBN 13 : 0698184106
Total Pages : 370 pages
Book Rating : 4.6/5 (981 download)

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Book Synopsis Miracle Cure by : William Rosen

Download or read book Miracle Cure written by William Rosen and published by Penguin. This book was released on 2017-05-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

Biography of Resistance

Author : Muhammad H. Zaman
Publisher : HarperCollins
ISBN 13 : 0062862987
Total Pages : 300 pages
Book Rating : 4.0/5 (628 download)

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Book Synopsis Biography of Resistance by : Muhammad H. Zaman

Download or read book Biography of Resistance written by Muhammad H. Zaman and published by HarperCollins. This book was released on 2020-04-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

Cases in Chemical Pathology

Author : R. N. Walmsley
Publisher : World Scientific
ISBN 13 : 9789810240356
Total Pages : 304 pages
Book Rating : 4.2/5 (43 download)

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Book Synopsis Cases in Chemical Pathology by : R. N. Walmsley

Download or read book Cases in Chemical Pathology written by R. N. Walmsley and published by World Scientific. This book was released on 1999 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the fourth edition of a highly regarded text which was first published in 1988. It introduces the reader to the interpretation of routine laboratory biochemical test results and covers all aspects of interpretative chemical pathology (including reproductive endocrinology, which was not covered previously). The approach is based on case material from the authors' laboratory and employs algorithms and similar aids for interpretation. The material is structured so that it is comprehensible to beginners as well as being useful for the more experienced practitioners. The envisaged audience is medical undergraduates, general practitioners, clinical biochemists and laboratory technicians.

The Good Virus

Author : Tom Ireland
Publisher : Hodder Paperbacks
ISBN 13 : 9781529365283
Total Pages : 0 pages
Book Rating : 4.3/5 (652 download)

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Book Synopsis The Good Virus by : Tom Ireland

Download or read book The Good Virus written by Tom Ireland and published by Hodder Paperbacks. This book was released on 2024-06-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: CHOSEN AS A BOOK OF THE YEAR 2023 BY WATERSTONES AND THE TIMES 'The book that might change the world ... This is luxury-class science writing' TELEGRAPH 'One of the best books of any genre that I've read in 2023, this superbly-written book ... will fascinate absolutely everyone.' FORBES 'A delight. To learn more about phages is to discover fascinating details about a hidden world' NATURE 'Outstanding' CLIVE MYRIE The viruses that do us harm are vastly outnumbered by viruses that can actually save lives. These good viruses are called 'phages', and they are the most abundant life form on Earth. The Good Virus reveals how these weird and wonderful microbes shape our health, support our ecosystems and could be the future of medicine.

Practical Handbook of Microbiology

Author : Lorrence H Green
Publisher : CRC Press
ISBN 13 : 1000245039
Total Pages : 2032 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Practical Handbook of Microbiology by : Lorrence H Green

Download or read book Practical Handbook of Microbiology written by Lorrence H Green and published by CRC Press. This book was released on 2021-05-04 with total page 2032 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Handbook of Microbiology, 4th edition provides basic, clear and concise knowledge and practical information about working with microorganisms. Useful to anyone interested in microbes, the book is intended to especially benefit four groups: trained microbiologists working within one specific area of microbiology; people with training in other disciplines, and use microorganisms as a tool or "chemical reagent"; business people evaluating investments in microbiology focused companies; and an emerging group, people in occupations and trades that might have limited training in microbiology, but who require specific practical information. Key Features Provides a comprehensive compendium of basic information on microorganisms—from classical microbiology to genomics. Includes coverage of disease-causing bacteria, bacterial viruses (phage), and the use of phage for treating diseases, and added coverage of extremophiles. Features comprehensive coverage of antimicrobial agents, including chapters on anti-fungals and anti-virals. Covers the Microbiome, gene editing with CRISPR, Parasites, Fungi, and Animal Viruses. Adds numerous chapters especially intended for professionals such as healthcare and industrial professionals, environmental scientists and ecologists, teachers, and businesspeople. Includes comprehensive survey table of Clinical, Commercial, and Research-Model bacteria. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license. Chapter 21, "Archaea," of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license available at http://www.taylorfrancis.com See Emanuel Goldman's Open Access article: "Lamarck redux and other false arguments against SARS-CoV-2 vaccination," https://www.embopress.org/doi/full/10.15252/embr.202254675

RNA

Author : James E. Darnell
Publisher :
ISBN 13 : 9781936113194
Total Pages : 0 pages
Book Rating : 4.1/5 (131 download)

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Book Synopsis RNA by : James E. Darnell

Download or read book RNA written by James E. Darnell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules could function as catalysts. --

Madness and Memory

Author : Stanley B. Prusiner
Publisher : Yale University Press
ISBN 13 : 0300191146
Total Pages : 344 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Madness and Memory by : Stanley B. Prusiner

Download or read book Madness and Memory written by Stanley B. Prusiner and published by Yale University Press. This book was released on 2014-04-29 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author, a 1997 recipient of the Noble Prize in medicine, describes the years he spent researching and demonstrating how the infectious proteins known as prions were responsible for brain diseases and how his theory has now become widely accepted in the science establishment.

Strange Bedfellows

Author : Ina Park
Publisher : Flatiron Books
ISBN 13 : 1250206650
Total Pages : 320 pages
Book Rating : 4.2/5 (52 download)

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Book Synopsis Strange Bedfellows by : Ina Park

Download or read book Strange Bedfellows written by Ina Park and published by Flatiron Books. This book was released on 2021-02-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Joyful and funny . . . Park uses science, compassion, humor, diverse stories and examples of her own shame-free living to take the stigma out of these infections." —The New York Times With curiosity and wit, Strange Bedfellows rips back the bedsheets to expose what really happens when STDs enter the sack. Sexually transmitted diseases have been hidden players in our lives for the whole of human history, with roles in everything from World War II to the growth of the Internet to The Bachelor. But despite their prominence, STDs have been shrouded in mystery and taboo for centuries, which begs the question: why do we know so little about them? Enter Ina Park, MD, who has been pushing boundaries to empower and inform others about sexual health for decades. With Strange Bedfellows, she ventures far beyond the bedroom to examine the hidden role and influence of these widely misunderstood infections and share their untold stories. Covering everything from AIDS to Zika, Park explores STDs on the cellular, individual, and population-level. She blends science and storytelling with historical tales, real life sexual escapades, and interviews with leading scientists—weaving in a healthy dose of hilarity along the way. The truth is, most of us are sexually active, yet we’re often unaware of the universe of microscopic bedfellows inside our pants. Park aims to change this by bringing knowledge to the masses in an accessible, no-nonsense, humorous way—helping readers understand the broad impact STDs have on our lives, while at the same time erasing the unfair stigmas attached to them. A departure from the cone of awkward silence and shame that so often surrounds sexual health, Strange Bedfellows is the straight-shooting book about the consequences of sex that all curious readers have been looking for.

"Surely You're Joking, Mr. Feynman!": Adventures of a Curious Character

Author : Richard P. Feynman
Publisher : W. W. Norton & Company
ISBN 13 : 0393355683
Total Pages : 429 pages
Book Rating : 4.3/5 (933 download)

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Book Synopsis "Surely You're Joking, Mr. Feynman!": Adventures of a Curious Character by : Richard P. Feynman

Download or read book "Surely You're Joking, Mr. Feynman!": Adventures of a Curious Character written by Richard P. Feynman and published by W. W. Norton & Company. This book was released on 2018-02-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most famous science books of our time, the phenomenal national bestseller that "buzzes with energy, anecdote and life. It almost makes you want to become a physicist" (Science Digest). Richard P. Feynman, winner of the Nobel Prize in physics, thrived on outrageous adventures. In this lively work that “can shatter the stereotype of the stuffy scientist” (Detroit Free Press), Feynman recounts his experiences trading ideas on atomic physics with Einstein and cracking the uncrackable safes guarding the most deeply held nuclear secrets—and much more of an eyebrow-raising nature. In his stories, Feynman’s life shines through in all its eccentric glory—a combustible mixture of high intelligence, unlimited curiosity, and raging chutzpah. Included for this edition is a new introduction by Bill Gates.

Dr. Sebi 7 Day Juice Detox

Author : Kerri M Williams
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.6/5 (94 download)

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Book Synopsis Dr. Sebi 7 Day Juice Detox by : Kerri M Williams

Download or read book Dr. Sebi 7 Day Juice Detox written by Kerri M Williams and published by . This book was released on 2020-10-06 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh, alkaline green juice every day can be one of the best habits you'll ever cultivate on the Dr. Sebi Diet lifestyle. It's an easy way to reset your metabolism, regain vigor, heal and reverse disease. Touted as the second best drink - only next to natural spring water, alkaline juices and tamarind can act as replacements for unhealthy energy drinks, soda or carbonated drinks. In this guide, we'll take a look at: - Why Green juices may be all you need for complete healing - Why you should get started on the alkaline vegan diet with juices - How to get started on juicing even if you're completely new to the diet - What you'll need for a successful juicing detox - How to do a 7 Day Alkaline Juice Detox - Tips and Strategies for Success on Alkaline juicing - How to source for the best fresh and wild crafted ingredients - Approved juicing ingredients for your electric alkaline juice recipe - 9 ingredients you should never use for juicing even though they are touted as health foods - How to combine your alkaline juice with sea moss and herbs for your detox routineAlso included are: - A Daily Meal Plan with Alkaline fruit and veggie Juices, Tamarind juice, sea moss and herbs - Day by day step by step routine plan for juice detox - How to tell your juice detox is working - 3 best ways to break your juice detox fast - Extra tips on taking care of your liver and kidneys - And much more... Wanna learn more, click the BUY NOW button to learn today

Enhancing the Effectiveness of Team Science

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309316855
Total Pages : 255 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Enhancing the Effectiveness of Team Science by : National Research Council

Download or read book Enhancing the Effectiveness of Team Science written by National Research Council and published by National Academies Press. This book was released on 2015-07-15 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past half-century has witnessed a dramatic increase in the scale and complexity of scientific research. The growing scale of science has been accompanied by a shift toward collaborative research, referred to as "team science." Scientific research is increasingly conducted by small teams and larger groups rather than individual investigators, but the challenges of collaboration can slow these teams' progress in achieving their scientific goals. How does a team-based approach work, and how can universities and research institutions support teams? Enhancing the Effectiveness of Team Science synthesizes and integrates the available research to provide guidance on assembling the science team; leadership, education and professional development for science teams and groups. It also examines institutional and organizational structures and policies to support science teams and identifies areas where further research is needed to help science teams and groups achieve their scientific and translational goals. This report offers major public policy recommendations for science research agencies and policymakers, as well as recommendations for individual scientists, disciplinary associations, and research universities. Enhancing the Effectiveness of Team Science will be of interest to university research administrators, team science leaders, science faculty, and graduate and postdoctoral students.