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Author : Natasha Angeliqueh Jones
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.X/5 (4 download)
Download or read book The Function of Stall in Drosophila Oogenesis written by Natasha Angeliqueh Jones and published by . This book was released on 1999 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Emily Jean Franklin Ozdowski
Publisher :
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.X/5 (3 download)
Download or read book Extrinsic Regulation of Drosophila Oogenesis Via the ADAMTS Metalloprotease, Stall written by Emily Jean Franklin Ozdowski and published by . This book was released on 2006 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John Edward Smith
Publisher :
ISBN 13 :
Total Pages : 462 pages
Book Rating : 4.X/5 (4 download)
Download or read book The Regulation and Function of Daughterless During Drosophila Oogenesis written by John Edward Smith and published by . This book was released on 2002 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michelle S. Giedt
Publisher : Springer Nature
ISBN 13 : 1071629700
Total Pages : 447 pages
Book Rating : 4.0/5 (716 download)
Download or read book Drosophila Oogenesis written by Michelle S. Giedt and published by Springer Nature. This book was released on 2023-01-30 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume compiles numerous methods to explore fly oogenesis. Beginning with updated protocols from isolating and staining the ovary to numerous imaging techniques and genetic protocols for cell-specific assessment and CRISPR-mediated mutagenesis, the volume continues by detailing techniques from assessing cytoskeletal structures to uncovering protein-protein interactions, with closing chapters exploring how Drosophila oogenesis can be used in the classroom and in outreach programs to increase interest in biomedical research, STEM education, and STEM careers. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Drosophila Oogenesis: Methods and Protocols serves as an ideal guide for both new and expert researchers working with this robust and versatile model organism.
Author : Gary Steven Dodson
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.F/5 ( download)
Download or read book The Function of Src64 in Drosophila Melanogaster Oogenesis written by Gary Steven Dodson and published by . This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lisa Nicole Petrella
Publisher :
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.:/5 (769 download)
Download or read book Characterization of the Role of Hu-li Tai Shao During Drosophila Oogenesis written by Lisa Nicole Petrella and published by . This book was released on 2006 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul F. Lasko
Publisher : R. G. Landes
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.3/5 (91 download)
Download or read book Molecular Genetics of Drosophila Oogenesis written by Paul F. Lasko and published by R. G. Landes. This book was released on 1994 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic development of eggs in fruit fly (Drosophilia) is the most important model used by developmental biologists in understanding how we go from a fertilized egg to a fully developed organism. Insights into fruit fly genetics have also begun to provide an idea as to how humans develop. This text amasses and organizes information on nearly 400 genes affecting the origin and development of ova. It should aid understanding of the crucial processes in organisms development.
Author : Jing Meng
Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.:/5 (532 download)
Download or read book The Function of the Swallow Gene in Cytoskeletal Organization During Drosophila Oogenesis and Embryogenesis written by Jing Meng and published by . This book was released on 2003 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ann-Marie Carbery
Publisher :
ISBN 13 :
Total Pages : 267 pages
Book Rating : 4.:/5 (643 download)
Download or read book Function of Suppressor of Deltex During Drosophila Oogenesis written by Ann-Marie Carbery and published by . This book was released on 2004 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Annabelle Cynthia Elisabeth Dold
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)
Download or read book Investigating the Function of Makorin 1 in Drosophila Oogenesis written by Annabelle Cynthia Elisabeth Dold and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
![Download Analysis of Traffic Jam Function During Drosophila Oogenesis [microform] PDF Online Free](https://books.google.com/books/content/images/frontcover/RbGFtgAACAAJ?fife=w200-h370)
Author : Jeffrey David Alls
Publisher : Library and Archives Canada = Bibliothèque et Archives Canada
ISBN 13 : 9780494025468
Total Pages : 278 pages
Book Rating : 4.0/5 (254 download)
Download or read book Analysis of Traffic Jam Function During Drosophila Oogenesis [microform] written by Jeffrey David Alls and published by Library and Archives Canada = Bibliothèque et Archives Canada. This book was released on 2005 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traffic jam (tj) encodes a soma-specific Maf transcription factor required for morphogenesis of the gonads in Drosophila melanogaster. I examined the requirement of tj function throughout oogenesis by studying the expression of follicle cell type specific markers in tj mutant cell clones. I also examined the interaction between tj and JAK-Stat pathway genes using a variety of loss- and gain-of-function mutations. As well as regulating the expression of a number of adhesion molecules, TJ appears to be a general requirement in follicle cells for their proper differentiation throughout oogenesis. Depending on when cells lose tj, their subsequent differentiation is blocked or defective. This suggests that like other Mafs, TJ is a regulator of differentiation. Furthermore, my findings suggest that TJ interacts with the JAK-Stat pathway during oogenesis. I have also identified a possible interaction between TJ and the EGF receptor signaling pathway.
Download or read book Characterization of the Drosophila Egfl7/8 Ortholog During Oogenesis written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: During animal development precise coordination and regulation of cell proliferation, differentiation and cell death is required for proper tissue organization. This is achieved through specific cell communication by intercellular signals. Cell death, for example, is a mechanism utilized by multicellular organisms for several developmental processes such as elimination of damaged cells or morphological shaping. Apoptosis can be induced by intrinsic signals generated within the cells or from extrinsic signals received from the surrounding environment. This work centered on the analysis of the mechanisms and signals that trigger apoptosis during Drosophila oogenesis. Drosophila ovaries are composed of approximately 16-20 ovarioles, each of which contains a series of egg chambers that are proceeding through the 14 stages of oogenesis moving from the germarium toward the oviduct. For the mature egg to be formed cell death has to occur at specific stages both in the germline (nurse cells) and in the somatic cells (follicle cells). However, whether this apoptosis is caused by intrinsic or extrinsic signals is not known. In addition to this developmentally controlled cell death, apoptosis can also be induced by environmental cues. Under starvation, for example, there is an increase of apoptosis at particular stages: in the germarium and at mid-oogenesis. Mid-oogenesis (stage8/9) is when vitellogenesis starts. At these stages the state of the egg chambers are checked in order to eliminate, through apoptosis of the germline, defective egg chambers. In starved flies, through activation of this "check-point", oogenesis is blocked before vitellogeneis starts. It is not clear what are the signals that prevent apoptosis at mid-oogenesis in well-fed flies. In this study I have analyzed the function of a newly identified signaling molecule CG7447 during Drosophila oogenesis. My results indicate that CG7447 is required to prevent apoptosis at mid-oogenesis in well-fed flies. CG7447 R.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Download or read book The Role of Dysfusion in Drosophila Oogenesis written by and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yingshi Peng
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.4/5 (64 download)
Download or read book Probing Translational Control During Drosophila Oogenesi written by Yingshi Peng and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational control provides a key mechanism for the spatial and temporal regulation of eukaryotic gene expression. It plays a particularly important role in early embryonic development in organisms that rely heavily on maternally supplied mRNAs. The Drosophila developing oocyte serves as a valuable model for studying translational control. The Drosophila posterior determinant, nanos (nos), is translationally repressed throughout the oocyte cytoplasm except at the posterior pole. A multi-functional RNA-binding protein Glorund (Glo), the homolog of the mammalian hnRNP F/H family of proteins, represses translation of nos during oogenesis by targeting both translation initiation and translation elongation. To elucidate the molecular mechanism by which Glo regulates nos, I identified dFMRP as a Glo-interacting protein. By biochemically dissecting repression of nos translation in vitro, I demonstrated that dFMRP specifically inhibits translation elongation. Furthermore, I combined mutational analysis and in vivo and in vitro binding assays to show that Glo's qRRM2 domain specifically and directly interacts with dFMRP, suggesting that Glo's RNA-binding domains can also function as protein-protein interaction interfaces critical for its regulatory functions. Additionally, I applied ribosome footprint profiling to the Drosophila ovary at different developmental stages to identify maternal transcripts regulated during the translation elongation phase. A footprint peak-finding tool has been developed to detect transcriptome-wide ribosome stalling sites. My preliminary results suggest that developmentally regulated ribosome stalling sites may be widely present on Drosophila maternal transcripts. An A-/P-site mapping algorithm is currently under development to facilitate mechanistic analysis of ribosome stalling during oogenesis.
Download or read book The Role of Cyclin J in Drosophila Oogenesis: Interactions with the PiRNA Pathway written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of cyclin J in Drosophila oogenesis: Interactions with the piRNA pathway.
Author : Nancy Caroline Hawkins
Publisher :
ISBN 13 :
Total Pages : 438 pages
Book Rating : 4.:/5 (347 download)
Download or read book Multiple Roles for Encore During Drosophila Oogenesis written by Nancy Caroline Hawkins and published by . This book was released on 1996 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rahul Das
Publisher :
ISBN 13 :
Total Pages : 128 pages
Book Rating : 4.:/5 (925 download)
Download or read book The Roles of the Drosophila Protein Tribbles in Oogenesis and Insulin Signaling Pathway written by Rahul Das and published by . This book was released on 2015 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this dissertation, I examined the molecular mechanism of function of the Drosophila melanogaster protein Tribbles (Trbl) during oogenesis and larval development. Trbl is the founding member of an evolutionarily conserved family of kinase proteins that play diverse roles in cell signaling and energy homeostasis. In addition to the central Serine/Threonine kinase domain, members of the Tribbles gene family (Trib) shares C terminal mitogen activated protein kinase kinase MEK1 and E3 ubiquitin ligase COP1 binding motifs, the latter required for the degradation of target proteins via proteasome. During oogenesis, Trbl controls border cell (BC) cluster migration by mediating degradation of C/EBP transcription factor Slbo. I first investigated Trbl's role during oogenesis using a Trbl specific antisera. Trbl localizes to the nucleus of main body follicle cells (MBFC) up to stage 10 of oogenesis. In the case of BC, Trbl expresses in a complementary pattern to Slbo expression. The Trbl level decreases gradually as the BC cluster delaminates from the epithelium and starts migrating when Slbo protein level increases. Moreover, Slbo was found to be essential but not sufficient to decrease the Trbl level required for BC migration. In a wing misexpression screen for Trbl interacting proteins, I identified the Serine/Threonine protein kinase Akt, a major mediator of insulin signaling. In recent years, mammalian Trib3 and Trib2 proteins have been implicated in the regulation of Insulin signaling by inhibiting the activating phosphorylation of Akt, Given the central role of Akt in insulin signaling, I tested whether the function of Trib family in insulin signaling is evolutionarily conserved. Using Drosophila larval development as a model system, I found that Trbl has a conserved role in binding and inhibiting Akt phosphorylation-activation, implicating Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation. Finally, I have identified a previously unknown motif (R141) in Trib proteins essential for their function to regulate insulin signaling mediated growth and metabolism.
