Integrated Drug Discovery Technologies

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Publisher : CRC Press
ISBN 13 : 082474473X
Total Pages : 603 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Integrated Drug Discovery Technologies by : Houng-Yau Mei

Download or read book Integrated Drug Discovery Technologies written by Houng-Yau Mei and published by CRC Press. This book was released on 2002-03-19 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.

Handbook of Drug Screening

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Publisher : CRC Press
ISBN 13 : 0824741447
Total Pages : 619 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Handbook of Drug Screening by : Ramakrishna Seethala

Download or read book Handbook of Drug Screening written by Ramakrishna Seethala and published by CRC Press. This book was released on 2001-07-24 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.

High Throughput Screening

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Publisher : Springer Science & Business Media
ISBN 13 : 1592591809
Total Pages : 269 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis High Throughput Screening by : William P. Janzen

Download or read book High Throughput Screening written by William P. Janzen and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.

Index of Conference Proceedings

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Publisher :
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Index of Conference Proceedings by : British Library. Document Supply Centre

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2002 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Medicinal Chemistry II, Volume 2

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Publisher :
ISBN 13 :
Total Pages : 1266 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Comprehensive Medicinal Chemistry II, Volume 2 by : John Bodenhan Taylor

Download or read book Comprehensive Medicinal Chemistry II, Volume 2 written by John Bodenhan Taylor and published by . This book was released on 2007 with total page 1266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book comprises 8 volumes, with all chapter sections available as PDF or HTML, and includes bibliographical references and index.

Combinational Chemistry & High Throughput Screening

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Publisher :
ISBN 13 :
Total Pages : 64 pages
Book Rating : 4./5 ( download)

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Book Synopsis Combinational Chemistry & High Throughput Screening by :

Download or read book Combinational Chemistry & High Throughput Screening written by and published by . This book was released on 1999-06 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:

G Protein-Coupled Receptors in Drug Discovery

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Publisher : CRC Press
ISBN 13 : 1420028219
Total Pages : 376 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis G Protein-Coupled Receptors in Drug Discovery by : Kenneth H. Lundstrom

Download or read book G Protein-Coupled Receptors in Drug Discovery written by Kenneth H. Lundstrom and published by CRC Press. This book was released on 2005-07-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs

Microarrays and Microplates

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Publisher : Taylor & Francis
ISBN 13 : 1000951707
Total Pages : 194 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Microarrays and Microplates by : Ian Day

Download or read book Microarrays and Microplates written by Ian Day and published by Taylor & Francis. This book was released on 2023-05-31 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 'Advanced Methods' series is intended for advanced undergraduates, postgraduates and established research scientists. Titles in the series are designed to cover current important areas of research in life sciences, and include both theoretical background and detailed protocols. The aim is to give researchers sufficient theory, supported by references, to take the given protocols and adapt them to their particular experimental systems. Microarrays and Microplates title looks at the new microarray and microplate-based technologies which facilitate large-scale analysis of DNA sequence variants, mRNA molecules and proteins. The book provides a review of the various methodologies being used to identify genetic variants and gene regulation and guides readers through both the application of these methodologies and experimental procedures.

High Content Screening

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Publisher : Springer Science & Business Media
ISBN 13 : 1597452173
Total Pages : 437 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis High Content Screening by : D. Lansing Taylor

Download or read book High Content Screening written by D. Lansing Taylor and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic research has been primarily focused on hypothesis-driven research. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches. In contrast, drug discovery research in the pharmaceutical industry has embraced discovery-driven research for many years. A good example has been the discovery of active compounds from large chemical libraries, through screening campaigns. The success of the human genome project has also demonstrated the need for both academic researchers and industrial researchers to now understand the functions of genes and gene products. The cell is the basic unit of life and it has been at the cellular level where function can be demonstrated most cost-effectively and rapidly. High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell.

Advances in Drug Discovery Techniques

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Publisher : CRC Press
ISBN 13 : 9780471975090
Total Pages : 232 pages
Book Rating : 4.9/5 (75 download)

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Book Synopsis Advances in Drug Discovery Techniques by : Alan L. Harvey

Download or read book Advances in Drug Discovery Techniques written by Alan L. Harvey and published by CRC Press. This book was released on 1998-08-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to techniques for the discovery and evaluation of pharamcologically active compounds for therapeutic development, this book covers rational drug design, high-throughput screening, and genetic approaches to drug discovery. The authors focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. They examine typical screening studies and their link to robotics and informatics in detail and present an overview of current progress within anitsense therapeutics. The book explores the rapid changes in drug discovery resulting from developments in molecular biology, robotics, and informatics.

Environmental Health Perspectives

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Publisher :
ISBN 13 :
Total Pages : 1252 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Management of Chemical and Biological Samples for Screening Applications

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Publisher : John Wiley & Sons
ISBN 13 : 3527645268
Total Pages : 435 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Management of Chemical and Biological Samples for Screening Applications by : Mark Wigglesworth

Download or read book Management of Chemical and Biological Samples for Screening Applications written by Mark Wigglesworth and published by John Wiley & Sons. This book was released on 2012-12-05 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.

Progress in Drug Research

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Publisher : Springer Science & Business Media
ISBN 13 : 9783764360283
Total Pages : 316 pages
Book Rating : 4.3/5 (62 download)

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Book Synopsis Progress in Drug Research by : Ernst Jucker

Download or read book Progress in Drug Research written by Ernst Jucker and published by Springer Science & Business Media. This book was released on 1999 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Drug Research is a prestigious book series which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmacological research. It serves as an important source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.

Ion Channels

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Publisher : Springer Science & Business Media
ISBN 13 : 3540797297
Total Pages : 177 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Ion Channels by : Bernard Fermini

Download or read book Ion Channels written by Bernard Fermini and published by Springer Science & Business Media. This book was released on 2008-09-04 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim of this volume is to review recent advances in the field of ion channel related diseases. Following an overview chapter summarizing the current state of ion channel screening technologies, five topics covering areas such as cancer, cardiac arrhythmias, cystic fibrosis, and pain have been selected, and the current state of knowledge is presented by leading experts in their field. Each chapter is structured to cover the biological rationale for the target, the current status in the development of agents to treat the disease, and future prospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases.

Approaches to High Throughput Toxicity Screening

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Publisher : CRC Press
ISBN 13 : 9781439814345
Total Pages : 208 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Approaches to High Throughput Toxicity Screening by : C. K. Atterwill

Download or read book Approaches to High Throughput Toxicity Screening written by C. K. Atterwill and published by CRC Press. This book was released on 1999-12-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated approach to in vitro toxicology and ADME screening using new technologies and discussing how they might be applied to the safety assessment of new pharamceutical products in drug discovery.

High Throughput Screening

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Publisher : CRC Press
ISBN 13 : 1482269805
Total Pages : 700 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis High Throughput Screening by : John P. Devlin

Download or read book High Throughput Screening written by John P. Devlin and published by CRC Press. This book was released on 1997-05-06 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high

Combinatorial Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 3527607382
Total Pages : 694 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Combinatorial Chemistry by : Willi Bannwarth

Download or read book Combinatorial Chemistry written by Willi Bannwarth and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. "Experimental details and complete reaction data [...] are a constant theme running through this work" (Angewandte Chemie) "Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope" (Journal of the American Chemical Society)