The Fly Neuromuscular Junction Structure And Function

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The Fly Neuromuscular Junction: Structure and Function

Author : Vivian Budnik
Publisher : Elsevier
ISBN 13 : 0080469132
Total Pages : 424 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Fly Neuromuscular Junction: Structure and Function by : Vivian Budnik

Download or read book The Fly Neuromuscular Junction: Structure and Function written by Vivian Budnik and published by Elsevier. This book was released on 2006-11-02 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes. This book reviews outstanding work by recognized leaders in the fields of Drosophila cellular neurogenetics including developmental neurobiology, mechanisms of synaptic function, and experience dependent changes at synapses. The book also includes step-by-step protocols to study the cellular biology of the NMJ, making it a vital resource for researchers beginning their investigations with this system, for those who are training students and postdoctoral fellows in this area, or simply as a general reference material for neuroscientists and neuroscience professors in general. * Provides a synthesis of the main topics in modern neurogenetics * Includes step-by-step protocols for the use of the Drosophila NMJ system in neurobiology lab research * Offers genetic approaches to study synapse development and function *

Neuromuscular Junctions in Drosophila

Author :
Publisher : Academic Press
ISBN 13 : 9780080857770
Total Pages : 289 pages
Book Rating : 4.8/5 (577 download)

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Book Synopsis Neuromuscular Junctions in Drosophila by :

Download or read book Neuromuscular Junctions in Drosophila written by and published by Academic Press. This book was released on 1999-04-29 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach. This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories. Key Features * Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system * Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function * Written in clear language that is easily understandable to readers not already familiar with fruit fly research * Includes numerous diagrams and extensive reference lists

Muscle Development in Drosophilia

Author : Helen Sink
Publisher : Springer Science & Business Media
ISBN 13 : 0387329633
Total Pages : 214 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Muscle Development in Drosophilia by : Helen Sink

Download or read book Muscle Development in Drosophilia written by Helen Sink and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.

Myasthenia Gravis and Related Disorders

Author : Henry J. Kaminski
Publisher : Springer Science & Business Media
ISBN 13 : 1592593410
Total Pages : 397 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Myasthenia Gravis and Related Disorders by : Henry J. Kaminski

Download or read book Myasthenia Gravis and Related Disorders written by Henry J. Kaminski and published by Springer Science & Business Media. This book was released on 2002-10-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

Disorders of Voluntary Muscle

Author : George Karpati
Publisher : Cambridge University Press
ISBN 13 : 9780521650625
Total Pages : 800 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Disorders of Voluntary Muscle by : George Karpati

Download or read book Disorders of Voluntary Muscle written by George Karpati and published by Cambridge University Press. This book was released on 2001-07-12 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Biology of the NMDA Receptor

Author : Antonius M. VanDongen
Publisher : CRC Press
ISBN 13 : 142004415X
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Developmental Neurobiology

Author : Greg Lemke
Publisher : Academic Press
ISBN 13 : 9780123751676
Total Pages : 771 pages
Book Rating : 4.7/5 (516 download)

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Book Synopsis Developmental Neurobiology by : Greg Lemke

Download or read book Developmental Neurobiology written by Greg Lemke and published by Academic Press. This book was released on 2010-05-22 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke The best researchers in the field provide their conclusions in the context of the latest experimental results

Intermediate Filament Associated Proteins

Author :
Publisher : Academic Press
ISBN 13 : 0128034904
Total Pages : 602 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Intermediate Filament Associated Proteins by :

Download or read book Intermediate Filament Associated Proteins written by and published by Academic Press. This book was released on 2016-01-14 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermediate Filament Associated Proteins, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in intermediate filament associated proteins and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in intermediate filament associated proteins and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers

Behavioral Genetics of the Fly (Drosophila Melanogaster)

Author : Josh Dubnau
Publisher : Cambridge University Press
ISBN 13 : 1107009030
Total Pages : 309 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Behavioral Genetics of the Fly (Drosophila Melanogaster) by : Josh Dubnau

Download or read book Behavioral Genetics of the Fly (Drosophila Melanogaster) written by Josh Dubnau and published by Cambridge University Press. This book was released on 2014-06-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.

Muscles and Their Neural Control

Author : Graham Hoyle
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Muscles and Their Neural Control by : Graham Hoyle

Download or read book Muscles and Their Neural Control written by Graham Hoyle and published by John Wiley & Sons. This book was released on 1983 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurologie, Muskel, Muskelphysiologie.

Exocytosis and Endocytosis

Author : Andrei I. Ivanov
Publisher : Springer Science & Business Media
ISBN 13 : 1588298655
Total Pages : 407 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Exocytosis and Endocytosis by : Andrei I. Ivanov

Download or read book Exocytosis and Endocytosis written by Andrei I. Ivanov and published by Springer Science & Business Media. This book was released on 2008 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, skilled experts provide the most up-to-date, step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. The book is insightful to both newcomers and seasoned professionals. It offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.

Encyclopedia of Neuroscience, Volume 1

Author : Larry R. Squire
Publisher : Academic Press
ISBN 13 : 0080963935
Total Pages : 12505 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Neuroscience, Volume 1 by : Larry R. Squire

Download or read book Encyclopedia of Neuroscience, Volume 1 written by Larry R. Squire and published by Academic Press. This book was released on 2009-06-12 with total page 12505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon

Author :
Publisher : Academic Press
ISBN 13 : 0128033541
Total Pages : 534 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon by :

Download or read book The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon written by and published by Academic Press. This book was released on 2016-01-12 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field

The Crustacean Nervous System

Author : Konrad Wiese
Publisher : Springer Science & Business Media
ISBN 13 : 9783540669005
Total Pages : 652 pages
Book Rating : 4.6/5 (69 download)

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Book Synopsis The Crustacean Nervous System by : Konrad Wiese

Download or read book The Crustacean Nervous System written by Konrad Wiese and published by Springer Science & Business Media. This book was released on 2002 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique selection of reviews summarizes current knowledge in all major fields of crustacean neurobiology and all levels of their CNS organization, using lobster and crayfish. It not only imparts theoretical knowledge but also describes all available contemporary and advanced techniques, such as patch clamp recordings, microelectrode techniques, immunocytochemistry, and all methods of molecular genetics to identify cellular pathways of protein synthesis and peptidergic control. In summary, it is a comprehensive account of the research achievements in one of the major nervous systems besides the mammalian CNS.

Drosophila melanogaster

Author : Farzana Khan Perveen
Publisher : BoD – Books on Demand
ISBN 13 : 9535138537
Total Pages : 270 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Drosophila melanogaster by : Farzana Khan Perveen

Download or read book Drosophila melanogaster written by Farzana Khan Perveen and published by BoD – Books on Demand. This book was released on 2018-02-28 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.

Molecular Mechanisms Underlying Assembly and Maintenance of the Neuromuscular Junction

Author : Ruth Herbst
Publisher : Frontiers Media SA
ISBN 13 : 2889740404
Total Pages : 241 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Molecular Mechanisms Underlying Assembly and Maintenance of the Neuromuscular Junction by : Ruth Herbst

Download or read book Molecular Mechanisms Underlying Assembly and Maintenance of the Neuromuscular Junction written by Ruth Herbst and published by Frontiers Media SA. This book was released on 2022-01-17 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Spinal Muscular Atrophy

Author : Charlotte J Sumner
Publisher : Academic Press
ISBN 13 : 0128036869
Total Pages : 506 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Spinal Muscular Atrophy by : Charlotte J Sumner

Download or read book Spinal Muscular Atrophy written by Charlotte J Sumner and published by Academic Press. This book was released on 2016-10-24 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA Includes outstanding questions and perspectives for future investigations and key references for additional detailed study