The Fate Of The Male Germ Cell

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The Fate of the Male Germ Cell

Author : Richard Ivell
Publisher : Springer Science & Business Media
ISBN 13 : 1461559138
Total Pages : 335 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Fate of the Male Germ Cell by : Richard Ivell

Download or read book The Fate of the Male Germ Cell written by Richard Ivell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE FASCINATION The male germ cell is the only cell of the human organism that leaves the body when it has achieved its final, highly sophisticated structure and properties. The male germ cell is designed for one purpose only: to reach the female gametes and to fertilize them. The various stages in the development of the male germ cell are characterized by proliferative phases, by the recombination of the maternal and paternal chromosomes, and by the differentiation and development of a specialized transport vehicle, the spermato zoon. Furthermore, the establishment of a special pool of stem cells, the spermatogonia, guarantees the continuity of the sperm-generation process from puberty to old age. THE FATE OF THE MALE GERM CELL The destiny of any individual germ cell is determined by a program that we know only in fragments. On the one hand every human male is able to produce many billions of germ cells in his lifetime, yet the chance of any single sperm reaching and fertilizing the female germ cell is exceedingly rare. A fertility disturbance means that somewhere during the complicated playing out of the germ cell program mistakes are made, and the program fails. It is still a fact that more than 50% of men presenting with male factor infertility have to be diagnosed as idiopathic, largely because of our lack of knowledge and conse quent lack of appropriate diagnostic tools.

Genetics of Human Infertility

Author : P.H. Vogt
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318060984
Total Pages : 178 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Genetics of Human Infertility by : P.H. Vogt

Download or read book Genetics of Human Infertility written by P.H. Vogt and published by Karger Medical and Scientific Publishers. This book was released on 2017-09-12 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Oxford Textbook of Endocrinology and Diabetes

Author : John A.H. Wass
Publisher : Oxford University Press, USA
ISBN 13 : 0199235295
Total Pages : 2158 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Oxford Textbook of Endocrinology and Diabetes by : John A.H. Wass

Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

The Male Germ Cell

Author : Bernard Robaire
Publisher :
ISBN 13 :
Total Pages : 510 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis The Male Germ Cell by : Bernard Robaire

Download or read book The Male Germ Cell written by Bernard Robaire and published by . This book was released on 1991 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Endocrinology of the Testis and Male Reproduction

Author : Manuela Simoni
Publisher : Springer
ISBN 13 : 9783319444406
Total Pages : 1364 pages
Book Rating : 4.4/5 (444 download)

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Book Synopsis Endocrinology of the Testis and Male Reproduction by : Manuela Simoni

Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

The Immortal Germline

Author :
Publisher : Academic Press
ISBN 13 : 0128097531
Total Pages : 365 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Immortal Germline by :

Download or read book The Immortal Germline written by and published by Academic Press. This book was released on 2019-05-31 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immortal Germline, Volume 135 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Balbiani body, germ plasm and polarity, Wolbachia and the germline, Human germ line biology, Reproduction/immunity and sperm success, Mammalian spermatogenesis, Reproduction/regeneration and germ cells in planarians, Germline stem cell homeostasis, Germline soma interactions/sex determination, Reconstituting the mouse germ-cell specification pathway in vitro, Maternal Germ line inheritance of mitochondria, Transposon strategies, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on germ cells

Infertility in the Male

Author : Larry I. Lipshultz
Publisher : Cambridge University Press
ISBN 13 : 1139483242
Total Pages : 691 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Infertility in the Male by : Larry I. Lipshultz

Download or read book Infertility in the Male written by Larry I. Lipshultz and published by Cambridge University Press. This book was released on 2009-09-24 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Textbook of Clinical Embryology

Author : Kevin Coward
Publisher : Cambridge University Press
ISBN 13 : 110727625X
Total Pages : 408 pages
Book Rating : 4.1/5 (72 download)

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Book Synopsis Textbook of Clinical Embryology by : Kevin Coward

Download or read book Textbook of Clinical Embryology written by Kevin Coward and published by Cambridge University Press. This book was released on 2013-10-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.

Discovering Mechanisms During Spermatogonial Differentiation that Prepare Male Germ Cells for Meiosis

Author : Taylor Anthony Johnson
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Discovering Mechanisms During Spermatogonial Differentiation that Prepare Male Germ Cells for Meiosis by : Taylor Anthony Johnson

Download or read book Discovering Mechanisms During Spermatogonial Differentiation that Prepare Male Germ Cells for Meiosis written by Taylor Anthony Johnson and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis, the male germ cell maturation process, allows men to become and remain fertile for decades. Male fertility relies on fate decisions of different types of spermatogonia - spermatogonial stem cells maintain the germline long-term, undifferentiated progenitor spermatogonia divide and await the differentiation signal (retinoic acid, RA), and differentiating spermatogonia proceed forward into meiosis as spermatocytes to ultimately become sperm. Spermatogonial differentiation and meiotic initiation are indispensable transitions in spermatogenesis that remain poorly understood. The three studies within this dissertation, using a combination of in vivo and in vitro approaches, detail spermatogonial requirements in these two transitions. The first study (chapter two) scrutinizes and redefines a presumed dogma - the requirement of RA for the spermatogonia-to-spermatocyte (mitotic-to-meiotic) transition. The second study (chapter three) deciphers the differential responsiveness of spermatogonia to RA in the adult testis. The third study (chapter four) introduces a novel RNA binding protein required for the commitment to and completion of spermatogonial differentiation. The collective findings from these three studies both enrich our understanding of spermatogonial biology and propose avenues for treatments that can enhance or discontinue spermatogonial differentiation.

The Sertoli Cell

Author : Lonnie Dee Russell
Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Sertoli Cell by : Lonnie Dee Russell

Download or read book The Sertoli Cell written by Lonnie Dee Russell and published by . This book was released on 1993 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Fibroblast Growth Factor Family

Author : Andrew Baird
Publisher :
ISBN 13 :
Total Pages : 542 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Fibroblast Growth Factor Family by : Andrew Baird

Download or read book The Fibroblast Growth Factor Family written by Andrew Baird and published by . This book was released on 1991 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bovine Reproduction

Author : Richard M. Hopper
Publisher : John Wiley & Sons
ISBN 13 : 1118470850
Total Pages : 2735 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Bovine Reproduction by : Richard M. Hopper

Download or read book Bovine Reproduction written by Richard M. Hopper and published by John Wiley & Sons. This book was released on 2014-08-18 with total page 2735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bovine Reproduction is a comprehensive, current reference providing information on all aspects of reproduction in the bull and cow. Offering fundamental knowledge on evaluating and restoring fertility in the bovine patient, the book also places information in the context of herd health where appropriate for a truly global view of bovine theriogenology. Printed in full color throughout, the book includes 83 chapters and more than 550 images, making it the most exhaustive reference available on this topic. Each section covers anatomy and physiology, breeding management, and reproductive surgery, as well as obstetrics and pregnancy wastage in the cow. Bovine Reproduction is a welcome resource for bovine practitioners, theriogenologists, and animal scientists, as well as veterinary students and residents with an interest in the cow.

Germ Cell Development in C. elegans

Author : Tim Schedl
Publisher : Springer Science & Business Media
ISBN 13 : 1461440157
Total Pages : 434 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Germ Cell Development in C. elegans by : Tim Schedl

Download or read book Germ Cell Development in C. elegans written by Tim Schedl and published by Springer Science & Business Media. This book was released on 2012-08-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms. Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition. This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.

The Y Chromosome and Male Germ Cell Biology in Health and Diseases

Author : Yun-Fai Chris Lau
Publisher : World Scientific
ISBN 13 : 9812770437
Total Pages : 323 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis The Y Chromosome and Male Germ Cell Biology in Health and Diseases by : Yun-Fai Chris Lau

Download or read book The Y Chromosome and Male Germ Cell Biology in Health and Diseases written by Yun-Fai Chris Lau and published by World Scientific. This book was released on 2007 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The roles of mouse Y chromosome genes in spermatogenesis -- Male meiotic sex chromosome inactivation and meiotic silencing -- Insights into SRY action from sex reversal mutations -- The TSPY gene family -- Structure and function of AZFa locus in human spermatogenesis -- RBMY and DAZ in spermatogenesis -- Neurotrophic factors in the development of the postnatal male germ line -- Dickkopf-like 1-a protein unique to mammals that is associated both with formation of trophoblast stem cells and with spermatogenesis -- Antisense transcription in developing male germ cells -- The spermatogonial stem cell model -- Transplantation of germ cells and testis tissue -- Orthodox and unorthodox ways to initiate fertilization and development in mammals -- Pathogenesis of testicular germ cell tumors -- Origin of testicular germ cell neoplasia: the role of sex chromosomes.

Male Germline Stem Cells: Developmental and Regenerative Potential

Author : Kyle E. Orwig
Publisher : Springer Science & Business Media
ISBN 13 : 1617379735
Total Pages : 269 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis Male Germline Stem Cells: Developmental and Regenerative Potential by : Kyle E. Orwig

Download or read book Male Germline Stem Cells: Developmental and Regenerative Potential written by Kyle E. Orwig and published by Springer Science & Business Media. This book was released on 2010-12-16 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, Male Germline Stem Cells: Developmental and Regenerative Potential assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the fundamental issues now being explored by today’s generation of stem cell researchers, including the field’s potential for regenerative medicine. Ranging from an assessment of the pluripotency of primordial germ cells and their possible applications in treating testicular cancer, to the recovery of once-mordant fertilization-competent sperm, this volume has it all. It is a reference point for any scientist involved in related research as well as being a timely summation of what could prove to be a hugely exciting and very fruitful area of inquiry.

Fertility Preservation in Male Cancer Patients

Author : John P. Mulhall
Publisher : Cambridge University Press
ISBN 13 : 1107012120
Total Pages : 365 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Fertility Preservation in Male Cancer Patients by : John P. Mulhall

Download or read book Fertility Preservation in Male Cancer Patients written by John P. Mulhall and published by Cambridge University Press. This book was released on 2013-02-21 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by international authorities, this book is aimed at clinicians dealing with male patients rendered infertile by cancer therapy.

Encyclopedia of Reproduction

Author :
Publisher : Academic Press
ISBN 13 : 0128151455
Total Pages : 3905 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Reproduction by :

Download or read book Encyclopedia of Reproduction written by and published by Academic Press. This book was released on 2018-06-29 with total page 3905 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope