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The Concept Of Experimental Medicine According To Claude Bernard
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Book Synopsis An Introduction to the Study of Experimental Medicine by : Claude Bernard
Download or read book An Introduction to the Study of Experimental Medicine written by Claude Bernard and published by . This book was released on 1927 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: First English translation of the classical work on the principles of physiological investigation in life sciences.
Book Synopsis Experimental Medicine by : Claude Bernard
Download or read book Experimental Medicine written by Claude Bernard and published by Routledge. This book was released on 2018-01-18 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The French physiologist Claude Bernard was responisble for investigating the chemical phenomena of digestion. This text reproduces his research into experimental medicine. A new introduction looks at his impact on the world of medicine.
Book Synopsis Surgical Revolutions by : Luis H. Toledo-Pereyra
Download or read book Surgical Revolutions written by Luis H. Toledo-Pereyra and published by World Scientific. This book was released on 2011 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many surgical revolutions distinguish the history and evolution of surgery. Some are small, others more dominant, but each revolution improves the art and science of surgery. Surgical revolutionaries are indispensable in the conception and completion of any surgical revolution, initiating scientific and technological advances that propel surgical practice forward. Surgical revolutionaries can come in the guises of Lister (antisepsis), Halsted (surgical residency and safe surgery), Cushing (safe brain surgery), Wangensteen (gastrointestinal physiological surgery), Blalock (relief of cyanotic heart disease), Lillehei (open heart surgery), and many others. With the hindsight of history, we can recognize patterns of progress, evaluate means of advancing new ideas, and solidify details of innovative behavior that could lead to new surgical revolutions. This volume examines the following vital questions in detail: What is a surgical revolution and how do we recognize one? Are surgical revolutionaries different? Is there a way to educate new surgical revolutionaries? Can history provide enduring examples of surgical revolutions? Are there different kinds of surgical revolutions? What characterizes a surgical revolution in the context of science and technology? What surgical revolutions are on the horizon?
Book Synopsis Pavlov's Physiology Factory by : Daniel P. Todes
Download or read book Pavlov's Physiology Factory written by Daniel P. Todes and published by JHU Press. This book was released on 2002 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Russian physiologist and Nobel Prize winner Ivan Pavlov is most famous for his development of the concept of the conditioned reflex and the classic experiment in which he trained a dog to salivate at the sound of a bell. In this study, Daniel P. Todes explores Pavlov's early work in digestive physiology through the structures and practices of his landmark laboratory - the physiology department of the Imperial Institute for Experimental Medicine.
Book Synopsis Profiles in Cardiology by : John Willis Hurst
Download or read book Profiles in Cardiology written by John Willis Hurst and published by . This book was released on 2003 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of the short biographical profiles that have appeared monthly in the journal Clinical Cardiology from 1986 up to the present. The persons who are the subjects of these profiles are individuals who have contributed in a meaningful or unique way to knowledge in the field of cardiology.
Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Book Synopsis The Pursuit of Perfection by : Sheila Rothman
Download or read book The Pursuit of Perfection written by Sheila Rothman and published by Vintage. This book was released on 2011-04-06 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to live in a time when medical science can not only cure the human body but also reshape it? How should we as individuals and as a society respond to new drugs and genetic technologies? Sheila and David Rothman address these questions with a singular blend of history and analysis, taking us behind the scenes to explain how scientific research, medical practice, drug company policies, and a quest for peak performance combine to exaggerate potential benefits and minimize risks. They present a fascinating and factual story from the rise of estrogen and testosterone use in the 1920s and 1930s to the frenzy around liposuction and growth hormone to the latest research into the genetics of aging. The Rothmans reveal what happens when physicians view patients’ unhappiness and dissatisfaction with their bodies—short stature, thunder thighs, aging—as though they were diseases to be treated. The Pursuit of Perfection takes us from the early days of endocrinology (the belief that you are your hormones) to today’s frontier of genetic enhancements (the idea that you are your genes). It lays bare the always complicated and sometimes compromised positions of science, medicine, and commerce. This is the book to read before signing on for the latest medical fix.
Book Synopsis Can Theories be Refuted? by : Sandra Harding
Download or read book Can Theories be Refuted? written by Sandra Harding and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to a view assumed by many scientists and philosophers of science and standardly found in science textbooks, it is controlled ex perience which provides the basis for distinguishing between acceptable and unacceptable theories in science: acceptable theories are those which can pass empirical tests. It has often been thought that a certain sort of test is particularly significant: 'crucial experiments' provide supporting empiri cal evidence for one theory while providing conclusive evidence against another. However, in 1906 Pierre Duhem argued that the falsification of a theory is necessarily ambiguous and therefore that there are no crucial experiments; one can never be sure that it is a given theory rather than auxiliary or background hypotheses which experiment has falsified. w. V. Quine has concurred in this judgment, arguing that "our statements about the external world face the tribunal of sense experience not indi vidually but only as a corporate body". Some philosophers have thought that the Duhem-Quine thesis gra tuitously raises perplexities. Others see it as doubly significant; these philosophers think that it provides a base for criticism of the foundational view of knowledge which has dominated much of western thought since Descartes, and they think that it opens the door to a new and fruitful way to conceive of scientific progress in particular and of the nature and growth of knowledge in general.
Book Synopsis In the Name of Science by : F. Barbara Orlans
Download or read book In the Name of Science written by F. Barbara Orlans and published by Oxford University Press. This book was released on 1993-07-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few arguments in biomedical experimentation have stirred such heated debate in recent years as those raised by animal research. In this comprehensive analysis of the social, political, and ethical conflicts surrounding the use of animals in scientific experiments, Barbara Orlans judges both ends of the spectrum in this debate -- unconditional approval or rejection of animal experimentation -- to be untenable. Instead of arguing for either view, she thoughtfully explores the ground between the extremes, and convincingly makes the case for public policy reforms that serve to improve the welfare of laboratory animals without jeopardizing scientific endeavor. This book presents controversial issues in a balanced manner based on careful historical analysis and original research. Different mechanisms of oversight for animal experiments are compared and those that have worked well are identified. This compelling work will be of interest to biomedical scientists, ethicists, animal welfare advocates and other readers concerned with this critical issue.
Book Synopsis Experimental Animals by : Thalia Field
Download or read book Experimental Animals written by Thalia Field and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fiction. Stemming from a through-line of marital discord in the household of the great French vivisector, Claude Bernard, Thalia Field has discovered a number of voices, some famous, some forgotten, and allowed them all a moment in which to be heard again. This compelling tale is made up largely of excerpts and quotations, pieced together with great artistry. A beautiful and thought-provoking collage of a tale of rescued history and a sobering tribute to some of its victims. --Karen Joy Fowler Advancing what she started twenty years ago with her earliest explorations of essayistic fiction, Thalia Field has now composed what very well might be her life's work--a tragic, comical, and utterly fascinating tale of a marriage that vividly encapsulates not only the origins of experimental medicine, but an entire age that spirited experiments in literature, science, engineering, film, etc. It's nothing less than a history--gorgeously fictional, purposefully essayistic--of how we got where we are. --John D'Agata
Book Synopsis Unveiling Diabetes - Historical Milestones in Diabetology by : V. Jörgens
Download or read book Unveiling Diabetes - Historical Milestones in Diabetology written by V. Jörgens and published by Karger Medical and Scientific Publishers. This book was released on 2020-08-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: A history of diabetology told by renowned contributors, many have themselves already become a part of diabetes history. A must-have for every diabetologist! Diabetologists, diabetes educators, and many interested readers will appreciate this book. What is more, countless celebrations are planned for the 100th anniversary of the discovery of insulin: this book provides numerous illustrations, accounts of personal experiences, and critical remarks on the history of diabetology – in addition to the history of insulin. It spans an arc from antiquity to the work of Claude Bernard, Paul Langerhans, Josef von Mering, Apollinaire Bouchardat, Oskar Minkowski, E.P. Joslin, and F.M. Allen. The history of insulin is presented from the perspective of diabetologists from Scotland, Spain, Germany, and Poland. The history of oral antidiabetics is told by Harald Lebovitz, and the chapter about glitazones by Edwin Gale reads like a spy novel! Pierre Lefèbvre describes the work of the diabetologist Jean Pirart and the history of glucagon. Sir George Alberti has provided a chapter about the therapy of ketoacidosis, to which he himself made groundbreaking contributions. Nephropathy is presented by Hans-Henrik Parving, and Eva Kohner, Ronald Klein and Barbara E.K. Klein have contributed a chapter on retinopathy. Other contemporary topics such diabetes in pregnancy, diabetes technology, psychosocial aspects of diabetes, and the history of the EASD and ADA are also included in this book.
Book Synopsis Purpose & Desire by : J. Scott Turner
Download or read book Purpose & Desire written by J. Scott Turner and published by HarperCollins. This book was released on 2017-09-12 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: A professor, biologist, and physiologist argues that modern Darwinism’s materialist and mechanistic biases have led to a scientific dead end, unable to define what life is—and only an openness to the qualities of "purpose and desire" will move the field forward. Scott Turner contends. "To be scientists, we force ourselves into a Hobson’s choice on the matter: accept intentionality and purposefulness as real attributes of life, which disqualifies you as a scientist; or become a scientist and dismiss life’s distinctive quality from your thinking. I have come to believe that this choice actually stands in the way of our having a fully coherent theory of life." Growing research shows that life's most distinctive quality, shared by all living things, is purpose and desire: maintain homeostasis to sustain life. In Purpose and Desire, Turner draws on the work of Claude Bernard, a contemporary of Darwin revered among physiologists as the founder of experimental medicine, to build on Bernard’s "dangerous idea" of vitalism, which seeks to identify what makes "life" a unique phenomenon of nature. To further its quest to achieve a fuller understanding of life, Turner argues, science must move beyond strictly accepted measures that consider only the mechanics of nature. A thoughtful appeal to widen our perspective of biology that is grounded in scientific evidence, Purpose and Desire helps us bridge the ideological evolutionary divide.
Download or read book Brute Science written by Hugh LaFollette and published by Psychology Press. This book was released on 1996 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Questions about the scientific and moral status of biomedical experimentation are hotly debated in the media and in professional circles. The outcome of this debate will shape future public health policy. The authors expose the weaknesses in both the standard defense and standard criticisms of animal experimentation. This thorough investigation of one of today's most fiercely debated questions yields some unexpected conclusions.
Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman
Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Book Synopsis Animal and Translational Models for CNS Drug Discovery by : Robert A. McArthur
Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.
Book Synopsis Experimental Medicine by : Claude Bernard
Download or read book Experimental Medicine written by Claude Bernard and published by Transaction Publishers. This book was released on 1999 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among great men, Claude Bernard should be counted fortunate in that he has not become a mythical figure. Pasteur's discoveries are hardly more remarkable, though their immediate influence has been much greater, and his horizon was incontestably less broad. But Bernard remains a plain man, highly distinguished, but not obscured by the growth of a legend. His physiological researches may have immortalized his name, but Experimental Medicine never exerted the influence which it promised. What Bernard saw as the future of physiology remained for decades obscured, so his writings were only half understood. His influence, however, was exerted far beyond medicine. Stewart Wolf suggests that Claude Bernard's genius in physiological experimentation is similar to the extraordinary Sherlock Holmes' capacity to solve crimes and William Osler's uncanny abilities in clinical diagnosis. Like both of those creative searchers, Claude Bernard typically focused on findings that did not accord with prevailing theory. His curiosity led him to attempt to explain the finding by a tentative hypothesis; he would then devise an experiment. Although he sought for a quantitative result that might serve as a basis of a theory, he had little confidence in statistics as a guide to certainty. Bernard's opposition scientists' prevailing habit of segregating their inquiries into systems rather than studying the unified organism is particularly striking. This volume will be important for those in the medical field as well as those interested in the history of science.
Author :United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research Publisher : ISBN 13 : Total Pages :614 pages Book Rating :4.:/5 (327 download)
Book Synopsis The Belmont Report by : United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research
Download or read book The Belmont Report written by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and published by . This book was released on 1978 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
