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The Chemistry And Biochemistry Of Steroids
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Book Synopsis Chemistry and Biological Activity of Steroids by : Jorge António Ribeiro Salvador
Download or read book Chemistry and Biological Activity of Steroids written by Jorge António Ribeiro Salvador and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
Book Synopsis Steroid Chemistry at a Glance by : Daniel Lednicer
Download or read book Steroid Chemistry at a Glance written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.
Book Synopsis Oral Contraceptives and Steroid Chemistry in the People's Republic of China by : American Steroid Chemistry and Biochemistry Delegation
Download or read book Oral Contraceptives and Steroid Chemistry in the People's Republic of China written by American Steroid Chemistry and Biochemistry Delegation and published by . This book was released on 1977 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Chemistry and Biochemistry of Steroids by : Leland J. Chinn
Download or read book The Chemistry and Biochemistry of Steroids written by Leland J. Chinn and published by . This book was released on 1969 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Biochemistry by : Fasman
Download or read book Handbook of Biochemistry written by Fasman and published by CRC Press. This book was released on 1976-11-24 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: V.1- Protens; v.2.B. Nucleic acids; v.2c- Lipi ds, carbohydrates, stervides.
Download or read book Hormones written by Anthony W. Norman and published by Academic Press. This book was released on 2014-06-28 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Book Synopsis Basic Principles of Organic Chemistry by : John D. Roberts
Download or read book Basic Principles of Organic Chemistry written by John D. Roberts and published by . This book was released on 1977 with total page 1596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes.
Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore
Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Book Synopsis Polyketides and Steroids by : Jiaju Zhou
Download or read book Polyketides and Steroids written by Jiaju Zhou and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-09-23 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed as well. The 5th volume mainly illustrates the molecular formula and structures of polyketides and steroids.
Book Synopsis Steroids and Peptides by : Joseph B. Dence
Download or read book Steroids and Peptides written by Joseph B. Dence and published by John Wiley & Sons. This book was released on 1980 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biochemistry and Mode of Action of Hormones by :
Download or read book Biochemistry and Mode of Action of Hormones written by and published by . This book was released on 1978 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides by : Viqar Uddin Ahmad
Download or read book Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides written by Viqar Uddin Ahmad and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an essential reference guide to spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids. All compounds are arranged according to the structure of the aglycone, and, in its own class, by the increasing molecular weight, making Spectroscopic Data of Steroid Glycosides extremely useful for the structure elucidation of new natural products, particularly glycosides.
Download or read book Biochemistry written by John T. Tansey and published by John Wiley & Sons. This book was released on 2020-07-15 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry: An Integrative Approach with Expanded Topics is addressed to premed, biochemistry, and life science majors taking a two-semester biochemistry course. This version includes all 25 chapters, offering a holistic approach to learning biochemistry. An integrated, skill-focused approach to the study of biochemistry and metabolism Biochemistry integrates subjects of interest to undergraduates majoring in premed, biochemistry, life science, and beyond, while preserving a chemical perspective. Respected biochemistry educator John Tansey takes a unique approach to the subject matter, emphasizing problem solving and critical thinking over rote memorization. Key concepts such as metabolism, are introduced and then revisited and cross-referenced throughout the text to establish pattern recognition and help students commit their new knowledge to long-term memory. As part of WileyPLUS, Biochemistry includes access to video walkthroughs of worked problems, interactive elements, and expanded end-of-chapter problems with a wide range of subject matter and difficulty. Students will have access to both qualitative and quantitative worked problems, and videos model the biochemical reasoning students will need to master. This approach helps students learn to analyze data and make critical assessments of experiments—key skills for success across scientific disciplines. Introduces students in scientific majors to the basics of biochemistry and metabolism Integrates and synthesizes topics throughout the text, allowing students to learn through repetition and pattern recognition Emphasizes problem solving and reasoning skills essential to life sciences, including data analysis and research assessment Provides access to video walkthroughs of worked problems, interactive features, and additional study material through WileyPLUS This volume covers DNA, RNA, gene regulation, synthetic proteins, omics, plant biochemistry, and more. With this text, students studying a range of disciplines are empowered to develop a lasting foundation in biochemistry and metabolism that will serve them as they advance through their careers.
Book Synopsis Medicinal Chemistry by : Thomas Nogrady
Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
Book Synopsis Steroid Hormone Action by : Malcolm G. Parker
Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by IRL Press. This book was released on 1993 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. It should be of interest to molecular biologists, endocrinologists, pharmacologists and clinicians interested in gene regulation hormones and steroid antagonists.
Book Synopsis Drug Abuse and Addiction in Medical Illness by : Joris C. Verster
Download or read book Drug Abuse and Addiction in Medical Illness written by Joris C. Verster and published by Springer Science & Business Media. This book was released on 2012-07-06 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse and addiction are common in clinical practice. Often they interfere with patient treatment or require an alternative approach. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment is a major contribution to the literature, a gold standard title offering a comprehensive range of topics for those who care for patients with addiction, conduct research in this area, or simply have an interest in the field. Offering state-of-the-art information for all those working with drug abusing or addicted patients, or for those interested in this topic from other research perspectives, the volume is a first of its kind book -- rich, comprehensive, yet focused, addressing the needs of the very active theoretical, basic, and clinical research in the field. Comprised of 46 chapters organized in four sections and developed by the leading international experts, Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment covers virtually every core, as well as contemporary, topic on addiction, from the established theories to the most modern research and development in the field. Enhancing the educational value of the volume, every chapter includes an abstract and two boxes summarizing learning objectives and directions for future research. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment discusses the topic in a authoritative, systematic manner and is an indispensable reference for all clinicians and researchers interested in this rapidly changing field.
Book Synopsis Chemical and Biological Aspects of Steroid Conjugation by : S. Bernstein
Download or read book Chemical and Biological Aspects of Steroid Conjugation written by S. Bernstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a collaborative endeavor by a group of investigators to bring together in a single volume a critical discussion of the major facets of our knowledge, ranging from chemical to clinical aspects, of steroid conjugation. However, the important field of bile acid and bile alcohol conjugation has been discussed only superficially since it was decided arbitrarily to be outside the projected scope of the book. The reader is referred to the companion volume of this book, namely Physical Properties of Steroid Conjugates (by Bernstein, Dusza, and Joseph, Springer-Verlag New York 1968), for complemental information on individual conjugates. The Editors wish to thank Miss Elise Kramer for typing assistance. Also we wish to express our deep appreciation and gratitude to Mrs. Dorothy Budd, our copy-editor, and Mr. J. Joseph for their editorial assistance in making this book possible. SEYMOUR BERNSTEIN Pearl River, N. Y. January, 1970 SAMUEL SOLOMON V11 CONTENTS Preface . . . . VII Nomenclature a, Discussion of Nomenclature System x b, Trivial and Systematic Names. x List of Contributors . . . . . . . . Xl Chemistry: Synthesis and Characterization S. BERNSTEIN, 1. P. DUSZA, and J. P. JOSEPH Enzymological Aspects of Steroid Conjugation A. B. Roy . . . . . . . . . . 74 The Hydrolysis of Steroid Conjugates H. L. BRADLOW . . . . . 131 Isolation of Steroid Conjugates P. K. SITTERI. . . . . . . 182 The Biochemistry of the 3P-Hydroxy-Ll5-Steroid Sulfates K. D. ROBERTS and S. LIEBERMAN 219 Formation, Metabolism, and Transport of Estrogen Conjugates E. DICZFALUSY and M. LEVITZ. . . . . . . . . . . . .
