The Challenge Of The Low Dose

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Food Allergy

Author : Dean D. Metcalfe
Publisher : John Wiley & Sons
ISBN 13 : 1444358162
Total Pages : 1125 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Food Allergy by : Dean D. Metcalfe

Download or read book Food Allergy written by Dean D. Metcalfe and published by John Wiley & Sons. This book was released on 2011-08-31 with total page 1125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying a scientific approach this unique book covers both pediatric and adult adverse reactions to foods and food additives. Following the successful formula of the previous editions, Food Allergy has established itself asthe comprehensive reference for those treating patients with food allergy or suspected allergy. The book has been thoroughly revised and updated presenting new chapters devoted to food biotechnology and genetic engineering, seafood toxins, future approaches to therapy and hidden food allergens. Food Allergy, fourth edition, is divided into five sections featuring key concept boxes for each chapter. Displayed in a logical manner the book is a practical, readable reference for use in the hospital or private practice setting.

The Effects of Low Dose Radiation

Author : Elena Burlakova
Publisher : CRC Press
ISBN 13 : 9067644145
Total Pages : 443 pages
Book Rating : 4.0/5 (676 download)

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Book Synopsis The Effects of Low Dose Radiation by : Elena Burlakova

Download or read book The Effects of Low Dose Radiation written by Elena Burlakova and published by CRC Press. This book was released on 2004-08-31 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this book show the results of investigations performed by Russian scientists in the field of low dose irradiation action. It is confirmed that low doses do have effects on the human organism and the environment and that the most serious consequences are observed in the far post-irradiation period. This branch of radiobiology, which developed after the Chernobyl accident and studied its consequences, is discussed in detail. The main part of reviews and articles is devoted to the aspects of low dose effects on the human and animal genome and far post-irradiation consequences. New details of mechanisms of low dose action are shown and methods of their determination are discussed. Furthermore, the adaptive response of organisms and the low dose effects on the immune system are demonstrated. Also, the difference between protection mechanisms against low dose irradiation and against high dose irradiation is shown and proved.

Middleton's Allergy 2-Volume Set

Author : A Wesley Burks, MD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323085938
Total Pages : 1900 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Middleton's Allergy 2-Volume Set by : A Wesley Burks, MD

Download or read book Middleton's Allergy 2-Volume Set written by A Wesley Burks, MD and published by Elsevier Health Sciences. This book was released on 2013-10-18 with total page 1900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Boasting a worldwide reputation as the leading text in allergy and immunology, Middleton's Allergy continues its steadfast tradition of providing comprehensive coverage of state-of-the-art basic science, as well as authoritative guidance on the clinical concepts of day-to-day diagnosis and management of allergic disorders. Offering timely information that’s suited for clinicians and researchers alike, Middleton’s is a user-friendly and versatile source for the knowledge you need to provide optimal care to your patients! "A valuable source of reference and pre-sifted information ...the editors are to be commending in keeping the book up-to-date and clinically valuable." Reviewed by: Imnunology News, March 2015 Stay on top of continuous new developments in clinical allergy and immunology through online access to the Expert Consult site, which will feature regular updates as well as the fully searchable contents. Find all of the information you need quickly and easily with a glossary of allergy and immunology terms; highlighted key points for each chapter; hundreds of crystal-clear images with a full-color format, and access to relevant websites. Apply the latest scientific knowledge and clinical applications with new chapters on Innate and Adaptive Immunity, Immune Tolerance, Immunobiology of IgE and Its Receptors, Resolution of Allergic Inflammation, and Particulate and Allergen Interactions, plus sweeping updates throughout. Take full advantage of the major advances in asthma pathogenesis and management with significant updates on diagnosis, treatment, and special aspects of asthma. Obtain the best results from the newest therapeutics for allergic and immunologic diseases through an expanded discussion of immunotherapy that includes new chapters on Sublingual Immunotherapy, Biologics and Immunosuppressives in Asthma, and Alternative and Complementary Therapies.

Formulation and Analytical Development for Low-Dose Oral Drug Products

Author : Jack Zheng
Publisher : John Wiley & Sons
ISBN 13 : 0470056096
Total Pages : 506 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Formulation and Analytical Development for Low-Dose Oral Drug Products by : Jack Zheng

Download or read book Formulation and Analytical Development for Low-Dose Oral Drug Products written by Jack Zheng and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.

Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings)

Author : Jaideep Malhotra
Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN 13 : 9350900068
Total Pages : 246 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) by : Jaideep Malhotra

Download or read book Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) written by Jaideep Malhotra and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2012-12-15 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the 1st edition of the book Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings). The text is comprehensive, updated as per the present day requirements in the subject of infertility. In this edition of the book an effort is made to highlight the special problems and hurdles to provide infertility treatment in low resource setups. The book has 26 chapters. The first chapter deals with history of human assisted reproductive technology. Chapter two provides a comprehensive description of infertility in developing world. Next four chapters are dedicated to ART unit in low resource setting. Chapters from 9 to 12 deal with different conditions associated with infertility. Subsequent chapters describe setting up of ART unit, assisted reproductive technology and law and ethics related to ART. A comprehensive index is given at last.

Vaccines E-Book

Author : Walter A. Orenstein
Publisher : Elsevier Health Sciences
ISBN 13 : 0323393012
Total Pages : 2389 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Vaccines E-Book by : Walter A. Orenstein

Download or read book Vaccines E-Book written by Walter A. Orenstein and published by Elsevier Health Sciences. This book was released on 2017-04-07 with total page 2389 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Dermatotoxicology

Author : Klaus Peter Wilhelm
Publisher : CRC Press
ISBN 13 : 142000977X
Total Pages : 1044 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Dermatotoxicology by : Klaus Peter Wilhelm

Download or read book Dermatotoxicology written by Klaus Peter Wilhelm and published by CRC Press. This book was released on 2007-11-26 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated

Drug Discrimination

Author : Richard A. Glennon
Publisher : John Wiley & Sons
ISBN 13 : 1118023145
Total Pages : 534 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Drug Discrimination by : Richard A. Glennon

Download or read book Drug Discrimination written by Richard A. Glennon and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents Drug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to realize how medicinal chemists can apply the types of information that the paradigm routinely provides. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies provides in-depth analyses of the nature and use of drugs as discriminative stimuli and bridges some of the numerous gaps between medicinal chemistry, pharmacology, and psychology. Stressing the practical aspects of drug discrimination, including types of procedures, study design, data, and interpretation, the book details the advantages and limitations of drug discrimination studies versus other pharmacologic evaluations. Practical information from leading researchers in the field addresses specific topics and techniques that are of interest in drug discovery, evaluation, and development. A groundbreaking new guide to the applications of drug discrimination studies for medicinal chemistry and neuroscience, Drug Discrimination is essential for any scientist, researcher, or student whose interests involve the design, development, and/or action of drugs acting at the level of the central nervous system.

Radiobiology and Environmental Security

Author : Carmel E Mothersill
Publisher : Springer Science & Business Media
ISBN 13 : 940071999X
Total Pages : 387 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Radiobiology and Environmental Security by : Carmel E Mothersill

Download or read book Radiobiology and Environmental Security written by Carmel E Mothersill and published by Springer Science & Business Media. This book was released on 2011-10-17 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume – like the NATO Advanced Research Workshop on which it is based – addresses the fundamental science that contributes to our understanding of the potential risks from ecological terrorism, i.e. dirty bombs, atomic explosions, intentional release of radionuclides into water or air. Both effects on human health (DNA and systemic effects) and on ecosystems are detailed, with particular focus on environmentally relevant low-dose ranges. The state-of-the-art contributions to the book are authored by leading experts; they tackle the relevant questions from the perspectives of radiation genetics, radiobiology, radioecology, radiation epidemiology and risk assessment.

Risk Management for Food Allergy

Author : Charlotte Madsen
Publisher : Academic Press
ISBN 13 : 012381989X
Total Pages : 335 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Risk Management for Food Allergy by : Charlotte Madsen

Download or read book Risk Management for Food Allergy written by Charlotte Madsen and published by Academic Press. This book was released on 2013-11-13 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk Management for Food Allergy is developed by a team of scientists and industry professionals who understand the importance of allergen risk assessment and presents practical, real-world guidance for food manufacturers. With more than 12 million Americans suffering from food allergies and little indication of what is causing that number to continue to grow, food producers, packagers and distributors need to appropriately process, label and deliver their products to ensure the safety of customers with allergic conditions. By identifying risk factors during processing as well as determining appropriate "safe" thresholds of ingredients, the food industry must take increasingly proactive steps to avoid direct or cross-contamination as well as ensuring that their products are appropriately labeled and identified for those at risk. This book covers a range of critical topics in this area, including the epidemiology of food allergy, assessing allergen thresholds and risk, specifics of gluten management and celiac disease, and much more. The practical advice on factory risk management, catering industry practices, allergen detection and measurement and regulatory controls is key for food industry professionals as well as regulators in government and other public bodies. - Science-based insights into the potential risks of food allergens - Focused section on determining thresholds - Practical guidance on food allergen risk management, including case studies

The Effect of Diet and Nutrition on Postprandial Metabolism

Author : François Mariotti
Publisher : MDPI
ISBN 13 : 303943232X
Total Pages : 210 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis The Effect of Diet and Nutrition on Postprandial Metabolism by : François Mariotti

Download or read book The Effect of Diet and Nutrition on Postprandial Metabolism written by François Mariotti and published by MDPI. This book was released on 2020-11-04 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The postprandial period is the metabolic phase that directly follows the ingestion of a meal. This period is critical to the handling of nutrients to feed the body throughout the whole day but it is also a time of challenge for the body’s metabolism, which has to be flexible and adaptable regarding the quantity and the quality of the nutrient intake. Changes in postprandial metabolism have been considered to be potential early markers in the pathophysiological course, finally leading to an increased risk of disease development. This book aimed to broaden and add to the research on the importance of postprandial metabolism in nutrition. The book includes literature reviews that cover the broad state of the art of our knowledge about postprandial metabolism, fine original studies of the complex changes in metabolism, and the physiological processes that are considered to drive the onset of pathogenesis. Finally, a series of examples on how nutrient content (especially proteins, sucrose, and lipids) can influence the postprandial metabolism over a wide range of phenomena operating during the postprandial period and how they could contribute to tipping the body towards adverse health processes.

Clinical Trial Biostatistics and Biopharmaceutical Applications

Author : Walter R. Young
Publisher : CRC Press
ISBN 13 : 1482212188
Total Pages : 582 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Clinical Trial Biostatistics and Biopharmaceutical Applications by : Walter R. Young

Download or read book Clinical Trial Biostatistics and Biopharmaceutical Applications written by Walter R. Young and published by CRC Press. This book was released on 2014-11-20 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1945, "The Annual Deming Conference on Applied Statistics" has been an important event in the statistics profession. In Clinical Trial Biostatistics and Biopharmaceutical Applications, prominent speakers from past Deming conferences present novel biostatistical methodologies in clinical trials as well as up-to-date biostatistical applications from the pharmaceutical industry. Divided into five sections, the book begins with emerging issues in clinical trial design and analysis, including the roles of modeling and simulation, the pros and cons of randomization procedures, the design of Phase II dose-ranging trials, thorough QT/QTc clinical trials, and assay sensitivity and the constancy assumption in noninferiority trials. The second section examines adaptive designs in drug development, discusses the consequences of group-sequential and adaptive designs, and illustrates group sequential design in R. The third section focuses on oncology clinical trials, covering competing risks, escalation with overdose control (EWOC) dose finding, and interval-censored time-to-event data. In the fourth section, the book describes multiple test problems with applications to adaptive designs, graphical approaches to multiple testing, the estimation of simultaneous confidence intervals for multiple comparisons, and weighted parametric multiple testing methods. The final section discusses the statistical analysis of biomarkers from omics technologies, biomarker strategies applicable to clinical development, and the statistical evaluation of surrogate endpoints. This book clarifies important issues when designing and analyzing clinical trials, including several misunderstood and unresolved challenges. It will help readers choose the right method for their biostatistical application. Each chapter is self-contained with references.

Practitioner's Guide to Empirically Based Measures of Anxiety

Author : Martin M. Antony
Publisher : Springer Science & Business Media
ISBN 13 : 0306476282
Total Pages : 517 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Practitioner's Guide to Empirically Based Measures of Anxiety by : Martin M. Antony

Download or read book Practitioner's Guide to Empirically Based Measures of Anxiety written by Martin M. Antony and published by Springer Science & Business Media. This book was released on 2006-04-10 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a single resource that contains information on almost all of the measures that have demonstrated usefulness in measuring the presence and severity of anxiety and related disorders. It includes reviews of more than 200 instruments for measuring anxiety-related constructs in adults. These measures are summarized in `quick view grids' which clinicians will find invaluable. Seventy-five of the most popular instruments are reprinted and a glossary of frequently used terms is provided.

Journal of the National Cancer Institute

Author :
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1981 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Health Effects of Low Radiation 2003

Author :
Publisher : Thomas Telford
ISBN 13 : 0727732013
Total Pages : 190 pages
Book Rating : 4.7/5 (277 download)

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Book Synopsis Health Effects of Low Radiation 2003 by :

Download or read book Health Effects of Low Radiation 2003 written by and published by Thomas Telford. This book was released on 2002-10 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This CD rom contains 28 papers presented to the BNES international conference on the health effects of low level ratiation. This conference is the fourth in the highly successful series and its aim is to present the fundamental radiobiological and dosimetric information relevant to understanding the current debate on the health effects of exposure to ionizing radiations at low doses and dose rates. It is also intended to provide a forum for discussion of the latest developments in this area and their relevance to the radiological protection of human health and the environment.

Nanoparticulate Vaccine Delivery Systems

Author : Martin J. D'Souza
Publisher : CRC Press
ISBN 13 : 9814613312
Total Pages : 239 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Nanoparticulate Vaccine Delivery Systems by : Martin J. D'Souza

Download or read book Nanoparticulate Vaccine Delivery Systems written by Martin J. D'Souza and published by CRC Press. This book was released on 2015-06-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen the development of novel technologies that use nanoparticles and microparticles to deliver vaccines by the oral and microneedle-based transdermal route of administration. These new technologies enable the formulation of vaccine particles containing vaccine antigens, without loss of their biological activity during the formula

Human and Ecological Risk Assessment

Author : Dennis J. Paustenbach
Publisher : John Wiley & Sons
ISBN 13 : 1119551102
Total Pages : 1319 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Human and Ecological Risk Assessment by : Dennis J. Paustenbach

Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-23 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.