The Cellular Basis Of Cardiovascular Function In Health And Disease

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The Cellular Basis of Cardiovascular Function in Health and Disease

Author : Pawan K. Singal
Publisher : Springer Science & Business Media
ISBN 13 : 1461557658
Total Pages : 336 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Cellular Basis of Cardiovascular Function in Health and Disease by : Pawan K. Singal

Download or read book The Cellular Basis of Cardiovascular Function in Health and Disease written by Pawan K. Singal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.

Cellular and Molecular Pathobiology of Cardiovascular Disease

Author : Monte Willis
Publisher : Academic Press
ISBN 13 : 0124055257
Total Pages : 339 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Cellular and Molecular Pathobiology of Cardiovascular Disease by : Monte Willis

Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Endocrinology of the Heart in Health and Disease

Author : Jonathan C. Schisler
Publisher : Academic Press
ISBN 13 : 0128031123
Total Pages : 378 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Endocrinology of the Heart in Health and Disease by : Jonathan C. Schisler

Download or read book Endocrinology of the Heart in Health and Disease written by Jonathan C. Schisler and published by Academic Press. This book was released on 2016-10-19 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Signal Transduction in the Cardiovascular System in Health and Disease

Author : Ashok K. Srivastava
Publisher : Springer
ISBN 13 : 9780387560762
Total Pages : 424 pages
Book Rating : 4.5/5 (67 download)

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Book Synopsis Signal Transduction in the Cardiovascular System in Health and Disease by : Ashok K. Srivastava

Download or read book Signal Transduction in the Cardiovascular System in Health and Disease written by Ashok K. Srivastava and published by Springer. This book was released on 2008-10-16 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

The Cardiovascular System

Author : Bruce Stillman
Publisher :
ISBN 13 : 9780879696788
Total Pages : 566 pages
Book Rating : 4.6/5 (967 download)

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Book Synopsis The Cardiovascular System by : Bruce Stillman

Download or read book The Cardiovascular System written by Bruce Stillman and published by . This book was released on 2003 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normal cardiovascular function requires the concerted action of many cell types, each capable of adaptive gene expression in response to developmental, physiological, and pathological cues. The genetic basis of cardiovascular function, development, and disease is an area of intense investigation, in the hope of significant insights into the heart and vessels? basic workings and improvements in diagnosis and therapy. This latest volume in a prestigious book series presents a remarkable survey of current progress in these efforts, through the contributions of over fifty of the world's leading investigators. Sections are devoted to angiogenesis, cardiogenesis, homeostasis, development, vascular biology, and cardiovascular repair and therapy. The book is an essential source of ideas, discoveries, and references for clinical scientists and physicians interested in basic cardiac biology, hypertension, atherosclerosis, coronary artery disease, and heart failure.

Signal Transduction in the Cardiovascular System in Health and Disease

Author : Ashok K. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 0387095519
Total Pages : 426 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Signal Transduction in the Cardiovascular System in Health and Disease by : Ashok K. Srivastava

Download or read book Signal Transduction in the Cardiovascular System in Health and Disease written by Ashok K. Srivastava and published by Springer Science & Business Media. This book was released on 2008-10-17 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Cardiac Cell Biology

Author : Elissavet Kardami
Publisher : Springer Science & Business Media
ISBN 13 : 9781402072963
Total Pages : 222 pages
Book Rating : 4.0/5 (729 download)

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Book Synopsis Cardiac Cell Biology by : Elissavet Kardami

Download or read book Cardiac Cell Biology written by Elissavet Kardami and published by Springer Science & Business Media. This book was released on 2003-02-28 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac cell biology has come of age. Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting factor in considering cell transplantion as a strategy to repair the damaged heart is cell availability at the right time. Cardiac gap junctions, intercellular communication channels that allow electrical and metabolic coupling and play an important role in arrhythmogenesis are now understood to be exquisite sensors of cardiac change. The reports in this volume incLude elegant studies that made use of cutting edge technological advances and many specialized reagents to address these issues.

Oxygen/Nitrogen Radicals: Cell Injury and Disease

Author : Val Vallyathan
Publisher : Springer Science & Business Media
ISBN 13 : 1461510872
Total Pages : 393 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oxygen/Nitrogen Radicals: Cell Injury and Disease by : Val Vallyathan

Download or read book Oxygen/Nitrogen Radicals: Cell Injury and Disease written by Val Vallyathan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Sex-Specific Analysis of Cardiovascular Function

Author : Peter L. M. Kerkhof
Publisher : Springer
ISBN 13 : 331977932X
Total Pages : 725 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Sex-Specific Analysis of Cardiovascular Function by : Peter L. M. Kerkhof

Download or read book Sex-Specific Analysis of Cardiovascular Function written by Peter L. M. Kerkhof and published by Springer. This book was released on 2018-07-26 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Molecular and Cellular Effects of Nutrition on Disease Processes

Author : Grant N. Pierce
Publisher : Springer Science & Business Media
ISBN 13 : 1461557631
Total Pages : 227 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular and Cellular Effects of Nutrition on Disease Processes by : Grant N. Pierce

Download or read book Molecular and Cellular Effects of Nutrition on Disease Processes written by Grant N. Pierce and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the 2nd World Conference of the International Society for Molecular Nutrition & Therapy. This conference was held on August 2-4, 1997, in Winnipeg, Canada. The goal of the conference was to advance our knowledge concerning the molecular events which link nutrition to various disease processes in the body. This volume represents an important compilation of unique articles addressing the molecular and cellular basis for the nutritional and therapeutic treatment of five general disease processes.

Bioenergetics of the Cell: Quantitative Aspects

Author : Valdur A. Saks
Publisher : Springer Science & Business Media
ISBN 13 : 1461556538
Total Pages : 444 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Bioenergetics of the Cell: Quantitative Aspects by : Valdur A. Saks

Download or read book Bioenergetics of the Cell: Quantitative Aspects written by Valdur A. Saks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.

Cellular Lipid Binding Proteins

Author : Jan Jansen
Publisher : Springer Science & Business Media
ISBN 13 : 1441992707
Total Pages : 229 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Cellular Lipid Binding Proteins by : Jan Jansen

Download or read book Cellular Lipid Binding Proteins written by Jan Jansen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well established that cellular lipid binding proteins serve central roles in cellular lipid uptake and metabolism. Evidence has been presented that various metabolic diseases, such as hyperlipidemia, atherosclerosis, insulin resistance, and diabetes, are characterized by malfunctioning or deficiencies in cellular lipid binding proteins. For better understanding of the action of lipids as signaling compounds and the role of lipids in intermediary metabolism, it is essential to have detailed knowledge of the interactions between lipids and their cognant binding proteins. In view of this growing interest in lipid-protein interaction, the 4th International Conference on Lipid Binding Proteins was held in Maastricht, The Netherlands, in June 2001. The proceedings of the previous three meetings have been published in Molecular and Cellular Biochemistry. The present focused issue of Molecular and Cellular Biochemistry comprises selected papers based on the lectures and posters presented during the 4th conference, and provides insight into the significance of these proteins for the functioning of the cell.

Biochemistry of Hypertrophy and Heart Failure

Author : Lorrie A. Kirshenbaum
Publisher : Springer Science & Business Media
ISBN 13 : 1441992383
Total Pages : 157 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Biochemistry of Hypertrophy and Heart Failure by : Lorrie A. Kirshenbaum

Download or read book Biochemistry of Hypertrophy and Heart Failure written by Lorrie A. Kirshenbaum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this special issue of Molecular and Cellular Biochemistry is underlying mechanisms that regulate cardiac growth. The new information provided in this special issue can be utilized to design new treatment modalities that will reduce the incidence of cardiac failure which will improve quality of life in patients with chronic heart disease.

A Molecular and Cellular View of Protein Kinase CK2

Author : Khalil Ahmed
Publisher : Springer Science & Business Media
ISBN 13 : 1441986243
Total Pages : 234 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis A Molecular and Cellular View of Protein Kinase CK2 by : Khalil Ahmed

Download or read book A Molecular and Cellular View of Protein Kinase CK2 written by Khalil Ahmed and published by Springer Science & Business Media. This book was released on 2012-09-18 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferation. The field of protein phosphorylation, including the enzymes involved in this post-translational modification, continues to advance at a fascinating pace. Since the first international meeting on this topic, held in Heidelberg in 1994, several new avenues of CK2 research have emerged despite persistent deficiencies in our understanding of the regulation of its activity. Among the significant new directions are studies related to the structure of the enzyme, especially its crystal structure, as well as an interesting aspect of CK2 function that involves its subunits as binding partners of several other proteins. In addition, new data have been gathered on the role of CK2 in transcription as well as in certain other cellular functions. To address these various aspects of the progress of CK2, a number of key scientists from different parts of the world came together at the second international meeting on `A Molecular and Cellular View of Protein Kinase CK2', held at Villard de Lans near Grenoble on September 24-26, 1997. The meeting was attended by nearly 50 participants and included 28 presentations, which provide a view of the latest progress on protein kinase CK2.

Control of Gene Expression by Catecholamines and the Renin-Angiotensin System

Author : Heinz Rupp
Publisher : Springer Science & Business Media
ISBN 13 : 1461543517
Total Pages : 227 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Control of Gene Expression by Catecholamines and the Renin-Angiotensin System by : Heinz Rupp

Download or read book Control of Gene Expression by Catecholamines and the Renin-Angiotensin System written by Heinz Rupp and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression. Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of many cells, the intriguing possibility arises that various disease are initiated or aggravated by such an imbalance. Catecholamine and angiotensin II influences can be in excess arising from, for example, hypercaloric food intake or psychosocial stress. During early progression of heart failure, sympathetic activity and angiotensin II influences also become increased. Due to beta-adrenergic receptor downregulation, depressed catecholamine influences are expected in the final stage of heart failure. An imbalanced influence of catecholamines and angiotensin II on gene expression leads to disordered molecular structures of the cell and an impaired cell function. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II. Basic biochemical processes are covered in detail and the potential of these pathways for explaining chronic diseases associated with excess catecholamine and angiotensin II influences should become apparent. It is hoped that this focussed issue triggers novel research into the development of drugs that are targeted at diseases characterized by an imbalanced gene expression involving catecholamines and angiotensin II.

Vascular Biochemistry

Author : Peter Zahradka
Publisher : Springer Science & Business Media
ISBN 13 : 1461502985
Total Pages : 194 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Vascular Biochemistry by : Peter Zahradka

Download or read book Vascular Biochemistry written by Peter Zahradka and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores all aspects of vascular biochemistry and includes chapters that provide an understanding of vascular function with descriptions of tissue components present in the vascular wall as well as an exploration of the hemodynamic and metabolic activities associated with this function. In addition, some chapters explore the vasculature under conditions which mimic various disease states. The information provided in this volume will provide new insights into the mechanisms that control vascular function as well as therapies designed to treat vascular disease.

Lipid Binding Proteins within Molecular and Cellular Biochemistry

Author : D.A. Bernlohr
Publisher : Springer Science & Business Media
ISBN 13 : 1461549299
Total Pages : 164 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Lipid Binding Proteins within Molecular and Cellular Biochemistry by : D.A. Bernlohr

Download or read book Lipid Binding Proteins within Molecular and Cellular Biochemistry written by D.A. Bernlohr and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The breadth of modern biology is characterized by a comprehension of phenomena at many levels of organization. Such levels of understanding range from the organismal to the molecular. It is when all these levels can be discussed together that a sense of true achievement begins to be felt. The topical area of fatty acid transport and metabolism was the focus of the Third International Conference on Lipid-Binding Proteins held at the University of Minnesota in May 1997. This volume contains a sampling of the proceedings of this meeting.