The Boxes Methodology Second Edition

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The BOXES Methodology Second Edition

Author : David W. Russell
Publisher : Springer Nature
ISBN 13 : 3030860698
Total Pages : 278 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis The BOXES Methodology Second Edition by : David W. Russell

Download or read book The BOXES Methodology Second Edition written by David W. Russell and published by Springer Nature. This book was released on 2021-11-18 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on how the BOXES Methodology, which is based on the work of Donald Michie, is applied to ill-defined real-time control systems with minimal a priori knowledge of the system. The method is applied to a variety of systems including the familiar pole and cart. This second edition includes a new section that covers some further observations and thoughts, problems, and evolutionary extensions that the reader will find useful in their own implementation of the method. This second edition includes a new section on how to handle jittering about a system boundary which in turn causes replicated run times to become part of the learning mechanism. It also addresses the aging of data values using a forgetfulness factor that causes wrong values of merit to be calculated. Another question that is addressed is “Should a BOXES cell ever be considered fully trained and, if so, excluded from further dynamic updates”. Finally, it expands on how system boundaries may be shifted using data from many runs using an evolutionary paradigm.

Inside the Box

Author : Drew Boyd
Publisher : Simon and Schuster
ISBN 13 : 145165930X
Total Pages : 8 pages
Book Rating : 4.4/5 (516 download)

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Book Synopsis Inside the Box by : Drew Boyd

Download or read book Inside the Box written by Drew Boyd and published by Simon and Schuster. This book was released on 2013-06-11 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The ‘inside-the-box approach’ can reveal key opportunities for innovation that are hiding in plain sight” (Daniel H. Pink, author of Drive). The traditional attitude toward creativity in the American business world is to “think outside the box”—to brainstorm without restraint in hopes of coming up with a breakthrough idea, often in moments of crisis. Sometimes it works, but it’s a problem-specific solution that does nothing to engender creative thinking more generally. Inside the Box demonstrates Systematic Inventive Thinking (SIT), which systemizes creativity as part of the corporate culture. This counterintuitive and powerfully effective approach to creativity requires thinking inside the box, working in one’s familiar world to create new ideas independent of specific problems. SIT’s techniques and principles have instilled creative thinking into such companies as Procter & Gamble, Johnson & Johnson, and other industry leaders. Inside the Box shows how corporations have successfully used SIT in business settings as diverse as medicine, technology, new product development, and food packaging. Dozens of books discuss how to make creative thinking part of a corporate culture, but none takes the innovative and unconventional approach of Inside the Box. With “inside the box” thinking, companies of any size can become sufficiently creative to solve problems even before they develop and to innovate on an ongoing basis. It’s a system that works! “Boyd and Goldenberg explain the basic building blocks for creativity and by doing so help all of us better express our potential” (Dan Ariely, author of Predictably Irrational).

Improving Almost Anything

Author : George E. P. Box
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 638 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Improving Almost Anything by : George E. P. Box

Download or read book Improving Almost Anything written by George E. P. Box and published by Wiley-Interscience. This book was released on 2006-04-21 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Masterworks in process improvement and quality technology— by George Box and friends George Box has a unique ability to explain complex ideas simply and eloquently. This revised edition of his masterworks since 1982 clearly demonstrates the range of his wit and intellect. These fascinating readings represent the cornerstones in the theory and application of process improvement, product design, and process control. Readers will gain valuable insights into the fundamentals and philosophy of scientific method using statistics and how it can drive creativity and discovery. The book is divided into five key parts: Part A, Some Thoughts on Quality Improvement, concerns the democratization of the scientific method and, in such papers as "When Murphy Speaks—Listen," advises managers to view operation of their processes as ongoing opportunities for improvement. Part B, Design of Experiments for Process Improvement, illustrates the enormous advantages offered by experimental design in the pursuit of better products and processes. Part C, Sequential Investigation and Discovery, shows how sequential assembly of designs allows the experimenter to match the difficulty of the problem with the effort needed to solve it. Part D, Control, describes application of feedback control in the Statistical Process Control (SPC) environment. A simple graphical technique using Box-Jenkins charts is set forth to appropriately adjust processes to target. Part E, Variance Reduction and Robustness, demonstrates how the existence of more than one source of variation may be used to achieve products robust to the environment in which they must function and emphasizes the importance of error transmission and data transformation in producing robust assemblies. A Foreword by Dr. J. Stuart Hunter allows readers to gain insight into the workings of a remarkable mind and explains how these ideas can greatly catalyze their efforts in process improvement.

Book Art Studio Handbook

Author : Stacie Dolin
Publisher : Quarry Books
ISBN 13 : 1610586204
Total Pages : 160 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Book Art Studio Handbook by : Stacie Dolin

Download or read book Book Art Studio Handbook written by Stacie Dolin and published by Quarry Books. This book was released on 2013-01-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: DIVHow to Make Books, Albums, Slipcases, and More /divDIVThereâ€™s nothing like making your own sketchbook, or wrapping a favorite book in the perfect homemade slipcase. And you can create it all yourself! Select the tools and materials youâ€™ll need, master basic book-binding techniques, and practice your new skills on 12 eye-catching projects. Then explore the gallery of variations for more inspiration to make each book form your own. Whether youâ€™re an experienced book binder or new to the art,Book Art Studio Handbookwill help you take your books to the next level./divDIV/divDIVWithBook Art Studio Handbook, youâ€™ll learn how to:/divDIV/divDIV-Set up your workspace or studio/divDIV-Choose the right board, paper, book cloth, and other supplies for your project/divDIV-Fold a textblock, make a sewing template, glue a cover, and practice other essential techniques/divDIV-Create albums: Imagine your photos in an Accordion Album with Frames, for example/divDIV- Create books: How about a flexible Tacketed Book to customize?/divDIV-Create enclosures: From Slipcase to French Box/divDIV-Challenge yourself: Try your hand at an advanced project, such as a Travel Journal/div

Research Methodology: Concepts and Cases, 2nd Edition

Author : Chawla Deepak & Neena Sodhi
Publisher : Vikas Publishing House
ISBN 13 : 9325982390
Total Pages : 820 pages
Book Rating : 4.3/5 (259 download)

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Book Synopsis Research Methodology: Concepts and Cases, 2nd Edition by : Chawla Deepak & Neena Sodhi

Download or read book Research Methodology: Concepts and Cases, 2nd Edition written by Chawla Deepak & Neena Sodhi and published by Vikas Publishing House. This book was released on with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: RESEARCH METHODOLOGY CONCEPT AND CASES provides a comprehensive and stepwise understanding of the research process with a balanced blend of theory, techniques and Indian illustrations from a wide cross-section of business areas. This book makes no presumptions and can be used with confidence and conviction by both students and experienced managers who need to make business sense of the data and information that is culled out through research groups. The conceptual base has been provided in comprehensive, yet simplistic detail, addressing even the minutest explanations required by the reader. The language maintains a careful balance between technical know-how and business jargon. Every chapter is profusely illustrated with business problems related to all domains—marketing, finance, human resource and operations. Thus, no matter what the interest area may be, the universal and adaptable nature of the research process is concisely demonstrated.

Response Surface Methodology

Author : Raymond H. Myers
Publisher : John Wiley & Sons
ISBN 13 : 1118210476
Total Pages : 596 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Response Surface Methodology by : Raymond H. Myers

Download or read book Response Surface Methodology written by Raymond H. Myers and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Second Edition: "This book [is for] anyone who would like a good, solid understanding of response surface methodology. The book is easy to read, easy to understand, and very applicable. The examples are excellent and facilitate learning of the concepts and methods." —Journal of Quality Technology Complete with updates that capture the important advances in the field of experimental design, Response Surface Methodology, Third Edition successfully provides a basic foundation for understanding and implementing response surface methodology (RSM) in modern applications. The book continues to outline the essential statistical experimental design fundamentals, regression modeling techniques, and elementary optimization methods that are needed to fit a response surface model from experimental data. With its wealth of new examples and use of the most up-to-date software packages, this book serves as a complete and modern introduction to RSM and its uses across scientific and industrial research. This new edition maintains its accessible approach to RSM, with coverage of classical and modern response surface designs. Numerous new developments in RSM are also treated in full, including optimal designs for RSM, robust design, methods for design evaluation, and experiments with restrictions on randomization as well as the expanded integration of these concepts into computer software. Additional features of the Third Edition include: Inclusion of split-plot designs in discussion of two-level factorial designs, two-level fractional factorial designs, steepest ascent, and second-order models A new section on the Hoke design for second-order response surfaces New material on experiments with computer models Updated optimization techniques useful in RSM, including multiple responses Thorough treatment of presented examples and experiments using JMP 7, Design-Expert Version 7, and SAS software packages Revised and new exercises at the end of each chapter An extensive references section, directing the reader to the most current RSM research Assuming only a fundamental background in statistical models and matrix algebra, Response Surface Methodology, Third Edition is an ideal book for statistics, engineering, and physical sciences courses at the upper-undergraduate and graduate levels. It is also a valuable reference for applied statisticians and practicing engineers.

Interpretable Machine Learning

Author : Christoph Molnar
Publisher : Lulu.com
ISBN 13 : 0244768528
Total Pages : 320 pages
Book Rating : 4.2/5 (447 download)

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Book Synopsis Interpretable Machine Learning by : Christoph Molnar

Download or read book Interpretable Machine Learning written by Christoph Molnar and published by Lulu.com. This book was released on 2020 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about making machine learning models and their decisions interpretable. After exploring the concepts of interpretability, you will learn about simple, interpretable models such as decision trees, decision rules and linear regression. Later chapters focus on general model-agnostic methods for interpreting black box models like feature importance and accumulated local effects and explaining individual predictions with Shapley values and LIME. All interpretation methods are explained in depth and discussed critically. How do they work under the hood? What are their strengths and weaknesses? How can their outputs be interpreted? This book will enable you to select and correctly apply the interpretation method that is most suitable for your machine learning project.

The BOXES Methodology

Author : David W. Russell
Publisher : Springer Science & Business Media
ISBN 13 : 1849965285
Total Pages : 226 pages
Book Rating : 4.8/5 (499 download)

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Book Synopsis The BOXES Methodology by : David W. Russell

Download or read book The BOXES Methodology written by David W. Russell and published by Springer Science & Business Media. This book was released on 2012-03-12 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robust control mechanisms customarily require knowledge of the system’s describing equations which may be of the high order differential type. In order to produce these equations, mathematical models can often be derived and correlated with measured dynamic behavior. There are two flaws in this approach one is the level of inexactness introduced by linearizations and the other when no model is apparent. Several years ago a new genre of control systems came to light that are much less dependent on differential models such as fuzzy logic and genetic algorithms. Both of these soft computing solutions require quite considerable a priori system knowledge to create a control scheme and sometimes complicated training program before they can be implemented in a real world dynamic system. Michie and Chambers’ BOXES methodology created a black box system that was designed to control a mechanically unstable system with very little a priori system knowledge, linearization or approximation. All the method needed was some notion of maximum and minimum values for the state variables and a set of boundaries that divided each variable into an integer state number. The BOXES Methodology applies the method to a variety of systems including continuous and chaotic dynamic systems, and discusses how it may be possible to create a generic control method that is self organizing and adaptive that learns with the assistance of near neighbouring states. The BOXES Methodology introduces students at the undergraduate and master’s level to black box dynamic system control , and gives lecturers access to background materials that can be used in their courses in support of student research and classroom presentations in novel control systems and real-time applications of artificial intelligence. Designers are provided with a novel method of optimization and controller design when the equations of a system are difficult or unknown. Researchers interested in artificial intelligence (AI) research and models of the brain and practitioners from other areas of biology and technology are given an insight into how AI software can be written and adapted to operate in real-time.

Program Evaluation Theory and Practice

Author : Donna M. Mertens
Publisher : Guilford Press
ISBN 13 : 1462503241
Total Pages : 642 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Program Evaluation Theory and Practice by : Donna M. Mertens

Download or read book Program Evaluation Theory and Practice written by Donna M. Mertens and published by Guilford Press. This book was released on 2012-02-20 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This engaging text takes an evenhanded approach to major theoretical paradigms in evaluation and builds a bridge from them to evaluation practice. Featuring helpful checklists, procedural steps, provocative questions that invite readers to explore their own theoretical assumptions, and practical exercises, the book provides concrete guidance for conducting large- and small-scale evaluations. Numerous sample studies—many with reflective commentary from the evaluators—reveal the process through which an evaluator incorporates a paradigm into an actual research project. The book shows how theory informs methodological choices (the specifics of planning, implementing, and using evaluations). It offers balanced coverage of quantitative, qualitative, and mixed methods approaches. Useful pedagogical features include: *Examples of large- and small-scale evaluations from multiple disciplines. *Beginning-of-chapter reflection questions that set the stage for the material covered. *"Extending your thinking" questions and practical activities that help readers apply particular theoretical paradigms in their own evaluation projects. *Relevant Web links, including pathways to more details about sampling, data collection, and analysis. *Boxes offering a closer look at key evaluation concepts and additional studies. *Checklists for readers to determine if they have followed recommended practice. *A companion website with resources for further learning.

Qualitative Research from Start to Finish, First Edition

Author : Robert K. Yin
Publisher : Guilford Press
ISBN 13 : 1606239783
Total Pages : 369 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Qualitative Research from Start to Finish, First Edition by : Robert K. Yin

Download or read book Qualitative Research from Start to Finish, First Edition written by Robert K. Yin and published by Guilford Press. This book was released on 2011-09-26 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively, practical text presents a fresh and comprehensive approach to doing qualitative research. The book offers a unique balance of theory and clear-cut choices for customizing every phase of a qualitative study. A scholarly mix of classic and contemporary studies from multiple disciplines provides compelling, field-based examples of the full range of qualitative approaches. Readers learn about adaptive ways of designing studies, collecting data, analyzing data, and reporting findings. Key aspects of the researcher's craft are addressed, such as fieldwork options, the five phases of data analysis (with and without using computer-based software), and how to incorporate the researcher's “declarative” and “reflective” selves into a final report. Ideal for graduate-level courses, the text includes:* Discussions of ethnography, grounded theory, phenomenology, feminist research, and other approaches.* Instructions for creating a study bank to get a new study started.* End-of-chapter exercises and a semester-long, field-based project.* Quick study boxes, research vignettes, sample studies, and a glossary.* Previews for sections within chapters, and chapter recaps.* Discussion of the place of qualitative research among other social science methods, including mixed methods research.

Power Distribution Planning Reference Book, Second Edition

Author : H. Lee Willis
Publisher : CRC Press
ISBN 13 : 9781420030310
Total Pages : 1246 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Power Distribution Planning Reference Book, Second Edition by : H. Lee Willis

Download or read book Power Distribution Planning Reference Book, Second Edition written by H. Lee Willis and published by CRC Press. This book was released on 2004-03-01 with total page 1246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing more than twice the content of the original edition, this new edition is the premier source on the selection, development, and provision of safe, high-quality, and cost-effective electric utility distribution systems, and it promises vast improvements in system reliability and layout by spanning every aspect of system planning including load forecasting, scheduling, performance, and economics. Responding to the evolving needs of electric utilities, Power Distribution Planning Reference Book presents an abundance of real-world examples, procedural and managerial issues, and engineering and analytical methodologies that are crucial to efficient and enhanced system performance.

Hal Leonard Bass Method Book 2

Author :
Publisher : Hal Leonard Corporation
ISBN 13 : 1476857458
Total Pages : 84 pages
Book Rating : 4.4/5 (768 download)

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Book Synopsis Hal Leonard Bass Method Book 2 by :

Download or read book Hal Leonard Bass Method Book 2 written by and published by Hal Leonard Corporation. This book was released on 1996-04-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Bass Method). The Hal Leonard Bass Method is designed for anyone just learning to play electric bass. It is based on years of teaching bass students of all ages and it also reflects some of the best bass teaching ideas from around the world. Book 2 teaches: the box shape; moveable boxes; notes in fifth position; major and minor scales; the classic blues line; the shuffle rhythm; tablature; and more!

Handbook of Monte Carlo Methods

Author : Dirk P. Kroese
Publisher : John Wiley & Sons
ISBN 13 : 1118014952
Total Pages : 627 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Handbook of Monte Carlo Methods by : Dirk P. Kroese

Download or read book Handbook of Monte Carlo Methods written by Dirk P. Kroese and published by John Wiley & Sons. This book was released on 2013-06-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of Monte Carlo simulation that explores the latest topics, techniques, and real-world applications More and more of today’s numerical problems found in engineering and finance are solved through Monte Carlo methods. The heightened popularity of these methods and their continuing development makes it important for researchers to have a comprehensive understanding of the Monte Carlo approach. Handbook of Monte Carlo Methods provides the theory, algorithms, and applications that helps provide a thorough understanding of the emerging dynamics of this rapidly-growing field. The authors begin with a discussion of fundamentals such as how to generate random numbers on a computer. Subsequent chapters discuss key Monte Carlo topics and methods, including: Random variable and stochastic process generation Markov chain Monte Carlo, featuring key algorithms such as the Metropolis-Hastings method, the Gibbs sampler, and hit-and-run Discrete-event simulation Techniques for the statistical analysis of simulation data including the delta method, steady-state estimation, and kernel density estimation Variance reduction, including importance sampling, latin hypercube sampling, and conditional Monte Carlo Estimation of derivatives and sensitivity analysis Advanced topics including cross-entropy, rare events, kernel density estimation, quasi Monte Carlo, particle systems, and randomized optimization The presented theoretical concepts are illustrated with worked examples that use MATLAB®, a related Web site houses the MATLAB® code, allowing readers to work hands-on with the material and also features the author's own lecture notes on Monte Carlo methods. Detailed appendices provide background material on probability theory, stochastic processes, and mathematical statistics as well as the key optimization concepts and techniques that are relevant to Monte Carlo simulation. Handbook of Monte Carlo Methods is an excellent reference for applied statisticians and practitioners working in the fields of engineering and finance who use or would like to learn how to use Monte Carlo in their research. It is also a suitable supplement for courses on Monte Carlo methods and computational statistics at the upper-undergraduate and graduate levels.

The BOXES Methodology Second Edition

Author : David W. Russell
Publisher :
ISBN 13 : 9783030860707
Total Pages : 0 pages
Book Rating : 4.8/5 (67 download)

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Book Synopsis The BOXES Methodology Second Edition by : David W. Russell

Download or read book The BOXES Methodology Second Edition written by David W. Russell and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on how the BOXES Methodology, which is based on the work of Donald Michie, is applied to ill-defined real-time control systems with minimal a priori knowledge of the system. The method is applied to a variety of systems including the familiar pole and cart. This second edition includes a new section that covers some further observations and thoughts, problems, and evolutionary extensions that the reader will find useful in their own implementation of the method. This second edition includes a new section on how to handle jittering about a system boundary which in turn causes replicated run times to become part of the learning mechanism. It also addresses the aging of data values using a forgetfulness factor that causes wrong values of merit to be calculated. Another question that is addressed is "Should a BOXES cell ever be considered fully trained and, if so, excluded from further dynamic updates". Finally, it expands on how system boundaries may be shifted using data from many runs using an evolutionary paradigm.

Constructing and Covering Boxes

Author : Tom Hollander
Publisher : Schiffer Craft
ISBN 13 : 9780764358913
Total Pages : 0 pages
Book Rating : 4.3/5 (589 download)

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Book Synopsis Constructing and Covering Boxes by : Tom Hollander

Download or read book Constructing and Covering Boxes written by Tom Hollander and published by Schiffer Craft. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2nd edition of the classic offers even more creative box examples and time-tested traditional-quality methods for book-art and multimedia craft lovers.

Statistical Methods in Diagnostic Medicine

Author : Xiao-Hua Zhou
Publisher : John Wiley & Sons
ISBN 13 : 1118626044
Total Pages : 597 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Statistical Methods in Diagnostic Medicine by : Xiao-Hua Zhou

Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

Biostatistical Methods

Author : John M. Lachin
Publisher : John Wiley & Sons
ISBN 13 : 1118625846
Total Pages : 676 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Biostatistical Methods by : John M. Lachin

Download or read book Biostatistical Methods written by John M. Lachin and published by John Wiley & Sons. This book was released on 2014-08-22 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition ". . . an excellent textbook . . . an indispensable reference for biostatisticians and epidemiologists." —International Statistical Institute A new edition of the definitive guide to classical and modern methods of biostatistics Biostatistics consists of various quantitative techniques that are essential to the description and evaluation of relationships among biologic and medical phenomena. Biostatistical Methods: The Assessment of Relative Risks, Second Edition develops basic concepts and derives an expanded array of biostatistical methods through the application of both classical statistical tools and more modern likelihood-based theories. With its fluid and balanced presentation, the book guides readers through the important statistical methods for the assessment of absolute and relative risks in epidemiologic studies and clinical trials with categorical, count, and event-time data. Presenting a broad scope of coverage and the latest research on the topic, the author begins with categorical data analysis methods for cross-sectional, prospective, and retrospective studies of binary, polychotomous, and ordinal data. Subsequent chapters present modern model-based approaches that include unconditional and conditional logistic regression; Poisson and negative binomial models for count data; and the analysis of event-time data including the Cox proportional hazards model and its generalizations. The book now includes an introduction to mixed models with fixed and random effects as well as expanded methods for evaluation of sample size and power. Additional new topics featured in this Second Edition include: Establishing equivalence and non-inferiority Methods for the analysis of polychotomous and ordinal data, including matched data and the Kappa agreement index Multinomial logistic for polychotomous data and proportional odds models for ordinal data Negative binomial models for count data as an alternative to the Poisson model GEE models for the analysis of longitudinal repeated measures and multivariate observations Throughout the book, SAS is utilized to illustrate applications to numerous real-world examples and case studies. A related website features all the data used in examples and problem sets along with the author's SAS routines. Biostatistical Methods, Second Edition is an excellent book for biostatistics courses at the graduate level. It is also an invaluable reference for biostatisticians, applied statisticians, and epidemiologists.