The Biology Of Hematopoiesis

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Hematopoietic Stem Cell Biology

Author : Motonari Kondo
Publisher : Springer Science & Business Media
ISBN 13 : 1603273476
Total Pages : 260 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Hematopoietic Stem Cell Biology by : Motonari Kondo

Download or read book Hematopoietic Stem Cell Biology written by Motonari Kondo and published by Springer Science & Business Media. This book was released on 2009-12-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine.

Modern Hematology

Author : Reinhold Munker
Publisher : Springer Science & Business Media
ISBN 13 : 1597451495
Total Pages : 505 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Modern Hematology by : Reinhold Munker

Download or read book Modern Hematology written by Reinhold Munker and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Modern Hematology: Biology and Clinical Management reflects the major advances in the understanding, diagnosis, and treatment of blood disorders. It describes the latest clinical and scientific developments as well as details targeted and molecular therapies. The book brings together facts, concepts, and protocols important for the practice of hematology. In 23 chapters, all major blood diseases are covered, as well as rare diseases that are of scientific interest. As in the previous edition, each chapter is illustrated by tables, figures, and a selection of color plates.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Author : Gerard Socie
Publisher : Academic Press
ISBN 13 : 0128134399
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation by : Gerard Socie

Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Pathophysiology of Blood Disorders

Author : Howard Franklin Bunn
Publisher : McGraw Hill Professional
ISBN 13 : 0071713786
Total Pages : 354 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Pathophysiology of Blood Disorders by : Howard Franklin Bunn

Download or read book Pathophysiology of Blood Disorders written by Howard Franklin Bunn and published by McGraw Hill Professional. This book was released on 2010-12-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise full-color review of the mechanisms of blood diseases and disorders – based on a Harvard Medical School hematology course 4 STAR DOODY'S REVIEW! "This is a superb book. Deceptively small, yet packs a wallop. The emphasis on principles instead of practice is welcome....The text is clear, concise, and surprisingly approachable for what could have been a very dense and dry discussion. I could not put this book down and read it entirely in one sitting. When was the last time anyone found a hematology textbook so riveting?"--Doody's Review Service Hematological Pathophysiology is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation and function of blood cells and hemostasis, as well as the pathophysiologic mechanisms responsible for the development of blood disorders. Featuring a strong emphasis on key principles, the book covers diagnosis and management primarily within a framework of pathogenesis. Authored by world-renowned clinician/educators at Harvard Medical School, Hematological Pathophysiology features content and organization based on a hematology course offered to second year students at that school. The book is logically divided into four sections: Anemias and Disorders of the Red Blood Cell, Disorders of Hemostasis and Thrombosis, Disorders of Leukocytes, and Transfusion Medicine; it opens with an important overview of blood and hematopoietic tissues. Features Succinct, to-the-point coverage that reflects current medical education More than 200 full-color photographs and renderings of disease mechanisms and blood diseases Each chapter includes learning objectives and self-assessment questions Numerous tables and diagrams encapsulate important information Incorporates the feedback of 180 Harvard medical students who reviewed the first draft -- so you know you’re studying the most relevant material possible

Theory of Hematopoiesis Control

Author : A.M. Dygai
Publisher : Springer
ISBN 13 : 3319085840
Total Pages : 100 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Theory of Hematopoiesis Control by : A.M. Dygai

Download or read book Theory of Hematopoiesis Control written by A.M. Dygai and published by Springer. This book was released on 2014-09-16 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph summarizes the large amount of experimental data accumulated during many years of studying the functions of the blood system and its regulatory mechanisms under the action of diverse morbific factors within the models of pathological processes (e.g. immobilization stress, blood loss, inflammation, cytostatic and radiation myelosuppressions, experimental encephalopathies, neuroses, and spontaneous leucosis). These data are is analyzed with the understanding that hematopoietic tissue is an integrated system that can react to the challenges of both the internal and external environments. This analysis helped develop the theory of hematopoiesis control describing the regularities in the work of basic subdivisions of the hematopoietic tissue under normal and pathological conditions, as well as the performance and interaction of the local and long-ranged control systems. The monograph is recommended for Physiologists, Pathophysiologists, Hematologists, Oncologists, Pharmacologists and other professionals.

Stem Cell Biology

Author : Daniel R. Marshak
Publisher : CSHL Press
ISBN 13 : 9780879696733
Total Pages : 566 pages
Book Rating : 4.6/5 (967 download)

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Book Synopsis Stem Cell Biology by : Daniel R. Marshak

Download or read book Stem Cell Biology written by Daniel R. Marshak and published by CSHL Press. This book was released on 2001 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells are the focus of intense interest from a growing, multidisciplinary community of investigators with new tools for isolating and characterizing these elusive cell types. This volume, which features contributions from many of the world's leading laboratories, provides a uniquely broad and authoritative basis for understanding the biology of stem cells and the current excitement about their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their potential for clinical exploitation. It is an essential work of reference for investigators in embryology, hematology, and neurobiology, and their collaborators in the emerging field of regenerative medicine.

Thomas' Hematopoietic Cell Transplantation

Author : Stephen J. Forman
Publisher : John Wiley & Sons
ISBN 13 : 1118416120
Total Pages : 1416 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Thomas' Hematopoietic Cell Transplantation by : Stephen J. Forman

Download or read book Thomas' Hematopoietic Cell Transplantation written by Stephen J. Forman and published by John Wiley & Sons. This book was released on 2015-12-14 with total page 1416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Histology and Cell Biology

Author : Douglas F. Paulsen
Publisher :
ISBN 13 : 9780071078719
Total Pages : 416 pages
Book Rating : 4.0/5 (787 download)

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Book Synopsis Histology and Cell Biology by : Douglas F. Paulsen

Download or read book Histology and Cell Biology written by Douglas F. Paulsen and published by . This book was released on 2010-07 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete one-stop review of the clinically important aspects of histology and cell biology--user-friendly, concise, and packed with learning aids! The ideal review for course exams and the USMLE! This popular title in the LANGE series is specifically designed to help you make the most of your study time--whether you're studying histology and cell biology for the first time or reviewing for course exams or the USMLE. With this focused review you will be able to pinpoint your weak areas, and then improve your comprehension with learning aids especially designed to help you understand and retain even the most difficult material. You will find complete easy-to-follow coverage of all the need-to-know material: fundamental concepts, the four basic tissues types, and organs and organ systems--presented in a consistent, time-saving design. At the conclusion of the book, you will find a Diagnostic Final Exam that has been updated with longer, case-related stems that mimic the USMLE Step 1 examination. Each chapter is devoted to one specific topic and includes learning aids such as: Objectives that point out significant facts and concepts that you must know about each topic Max Yield(tm) study questions that direct you to key facts needed to master material most often covered on exams A synopsis presented in outline form that reviews all the basic histology and related cell biology covered on exams Multiple-choice questions written in a style most commonly used in medical school NEW to this Edition: Thoroughly revised Q&A Completely updated text and practice questions to reflect current knowledge Information added to each chapter regarding relevant pathology/clinical issues; possibly as a separate colored box Visit www.LangeTextbooks.com to access valuable resources and study aids. Thorough coverage you won't find anywhere else! FUNDAMENTAL CONCEPTS: Methods of Study, The Plasma Membrane & Cytoplasm, The Nucleus & Cell Cycle, THE FOUR BASIC TISSUE TYPES: Epithelial Tissue, Connective Tissue, Adipose Tissue, Cartilage, Bone, Integrative Multiple-Choice Questions: Connective Tissues Nerve Tissue, Muscle Tissue, Integrative Multiple-Choice Questions: Basic Tissue Types, ORGANS & ORGAN SYSTEMS: Circulatory System, Peripheral Blood, Hematopoiesis, Lymphoid System, Digestive Tract, Glands Associated with the Digestive Tract, Integrative Multiple-Choice Questions: Digestive System, Respiratory System, Skin, Urinary System, Pituitary & Hypothalamus, Adrenals, Islets of Langerhans, Thyroid, Parathyroids, & Pineal Body, Male Reproductive System, Female Reproductive System, Integrative Multiple-Choice Questions: Endocrine System, Sense Organs, Diagnostic Final Examination

Exotic Animal Hematology and Cytology

Author : Terry W. Campbell
Publisher : John Wiley & Sons
ISBN 13 : 1118611160
Total Pages : 418 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Exotic Animal Hematology and Cytology by : Terry W. Campbell

Download or read book Exotic Animal Hematology and Cytology written by Terry W. Campbell and published by John Wiley & Sons. This book was released on 2015-02-12 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exotic Animal Hematology and Cytology, Fourth Edition updates the most comprehensive reference available on exotic animal hematology and cytology of all major species. Acts as both an atlas and a text, offering high-quality photographs and step-by-step descriptions of techniques associated with preparing and interpreting hematology and cytology samples Presents complete information on hematology and cytology in a wide range of exotic species, including small mammals, birds, reptiles, amphibians, and fish Includes more than 700 high-quality color photographs, now with sizing bars Takes a new disease-based structure for improved ease of use Provides straightforward step-by-step descriptions of sample preparation and interpretation

Hematopoietic Stem Cell Development

Author : Isabelle Godin
Publisher : Springer Science & Business Media
ISBN 13 : 0387335358
Total Pages : 188 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Hematopoietic Stem Cell Development by : Isabelle Godin

Download or read book Hematopoietic Stem Cell Development written by Isabelle Godin and published by Springer Science & Business Media. This book was released on 2010-05-27 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects articles on the biology of hematopoietic stem cells during embryonic development, reporting on fly, fish, avian and mammalian models. The text invites a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing conserved trends in development. The book reviews current knowledge on human hematopoietic development and discusses recent breakthroughs of relevance to both researchers and clinicians.

Stem Cells and the Future of Regenerative Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Concise Guide to Hematology

Author : Hillard M. Lazarus
Publisher : Springer
ISBN 13 : 331997873X
Total Pages : 540 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Concise Guide to Hematology by : Hillard M. Lazarus

Download or read book Concise Guide to Hematology written by Hillard M. Lazarus and published by Springer. This book was released on 2018-11-15 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive overview of the essential concepts and malignancies of hematology. Now in its second edition, the book reviews every major hematologic disorder and disease entity in thorough detail, from incidence and prevalence to patient and treatment-related issues. Formatted in an organized and easy-to-read outline style to facilitate rapid learning and information processing, the book allows readers to easily locate topics of immediate interest without wading through entire sections to obtain the desired data. Written by a diverse range of experts in the field, Concise Guide to Hematology, Second Edition is a valuable resource for clinicians, residents, trainees, and entry-level fellows who work in or are just entering the field of hematology.

Geriatric Oncology

Author : Martine Extermann
Publisher : Springer
ISBN 13 : 9783319574141
Total Pages : 1150 pages
Book Rating : 4.5/5 (741 download)

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Book Synopsis Geriatric Oncology by : Martine Extermann

Download or read book Geriatric Oncology written by Martine Extermann and published by Springer. This book was released on 2020-01-30 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as a comprehensive resource for clinicians and researchers seeking in-depth information on geriatric oncology. The coverage encompasses epidemiology, the biology and (patho)physiology of aging and cancer, geriatric assessment and management, hematologic malignancies, solid tumors, issues in patient care, and research methods. Since cancer is a disease of aging and people are living longer, most cancer patients are now aged 70 and older. Yet the more we age, the more diverse we become in terms of our health, biologic fitness, and cancer behavior. Typically, however, general oncology clinical trials address only a selected healthier and younger population of patients. Geriatric oncology is the area of oncology that addresses these issues but while a wealth of knowledge has been accumulated, information is often difficult to retrieve or insufficiently detailed. The SpringerReference program, in which this book is published, offers an ideal format for overcoming these limitations since it combines thorough coverage with access to living editions constantly updated chapter by chapter via a dynamic peer-review process, ensuring that information remains current and pertinent.

Hematopoietic Stem Cell Transplantation

Author : Kim Schmit-Pokorny
Publisher :
ISBN 13 : 9781635930412
Total Pages : pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Hematopoietic Stem Cell Transplantation by : Kim Schmit-Pokorny

Download or read book Hematopoietic Stem Cell Transplantation written by Kim Schmit-Pokorny and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Hematopoietic stem cell transplantation (HSCT) has evolved from primary use in hematologic malignancies and nonmalignant disease and solid tumors into a treatment option for many other diseases, and indications for HSCT continue to expand. The new edition of this manual provides comprehensive information on the ever-evolving specialty of HSCT, providing nurses and other practitioners with in-depth information on the entire HSCT process, from stem cell mobilization, collection, and infusion to potential complications and long-term effects. It also includes chapters on current research, emerging therapies, ethics, HSCT program development, and professional practice issues"--

Normal and Malignant Hematopoiesis

Author : Enrico Mihich
Publisher : Springer Science & Business Media
ISBN 13 : 1461519276
Total Pages : 251 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Normal and Malignant Hematopoiesis by : Enrico Mihich

Download or read book Normal and Malignant Hematopoiesis written by Enrico Mihich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: ''An exciting glance at key issues in contemporary hematopoiesis.'' -The Quarterly Review of Biology

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Essential Current Concepts in Stem Cell Biology

Author : Beate Brand-Saberi
Publisher : Springer Nature
ISBN 13 : 3030339238
Total Pages : 247 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Essential Current Concepts in Stem Cell Biology by : Beate Brand-Saberi

Download or read book Essential Current Concepts in Stem Cell Biology written by Beate Brand-Saberi and published by Springer Nature. This book was released on 2020-01-03 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.