The Atpases

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ATPases

Author : A.G. Lee
Publisher : Elsevier
ISBN 13 : 0080527701
Total Pages : 441 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis ATPases by : A.G. Lee

Download or read book ATPases written by A.G. Lee and published by Elsevier. This book was released on 1996-12-17 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 5 of Biomembranes covers an important group of membrane proteins, the ATPases. The P-type ATPases couple the hydrolysis of ATP to the movement of ions across a membrane and are characterized by the formation of a phosphoyrlated intermediate. Included are the plasma membrane and muscle sarcoplasmic reticulum Ca2+ -ATPases, the (Na+ -K+) -ATPase, the gastric (H+ -K+) -ATPase, the plasma membrane H+ -ATPase of fungi and plants, the Mg2+ - transport ATPase, the Salmonella typhimurium, and the K+ -ATPase of Escherichia coli, KdpB. The other important classes of ATPase in eukaryotic systems are the vacuolar H+ -ATPases and the F0F1 ATP synthase, and, in bacteria, the anion-translocating ATPases, responsible for resistance to arsenicals and antimonials, and the (Na+ -Mg2+) -ATPase of Acholeplasma. Finally, eukaryotic systems contain a variety of ectonucleotidases important, for example, in hydrolysis of extracellular ATP released as a cotransmitter from cholinergic and adrenergic nerve terminals. Volume 5 of Biomembranes explores structure-function relationships for these mebrane-bound ATPases.

Handbook of ATPases

Author : Masamitsu Futai
Publisher : John Wiley & Sons
ISBN 13 : 3527606289
Total Pages : 493 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Handbook of ATPases by : Masamitsu Futai

Download or read book Handbook of ATPases written by Masamitsu Futai and published by John Wiley & Sons. This book was released on 2006-01-24 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: ATP-dependent active ion transport enables cells to regulate their pH value and to control their ion composition. The reverse process, transforming an ion imbalance into chemical energy, drives mitochondrial and chloroplast ATP synthesis. The mediators of these fundamental processes are ion-motive ATPases, highly conserved enzymes that play key roles in cell physiology from bacteria to man. As the first comprehensive overview of this important class of enzymes, this handbook summarizes recent knowledge about the molecular mechanism of ATPases, relating this information to the physiology and pathopyhsiology of ion transport, mitochondrial function, vesicle transport and lysosomal acidification. All important P-type, F-type and V-type ATPases are treated systematically, complemented by a special section on the cell biology and physiology of acidic compartments, and backed by an extensive bibliography and index. This premier reference source for physiologists, molecular biologists, biophysicists and clinical researchers contains contributions by the world's foremost ATPase research groups.

Ion-motive ATPases

Author : Antonio Scarpa
Publisher :
ISBN 13 :
Total Pages : 540 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Ion-motive ATPases by : Antonio Scarpa

Download or read book Ion-motive ATPases written by Antonio Scarpa and published by . This book was released on 1992 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The large body of recent knowledge that has allowed the recent discovery of new ATPases and the partial clarification of structural and functional aspects of the already known ATPases are the subjects of this volume. A dozen ION-MOTIVE ATPases are discussed in terms of structure, site modification, catalysis, expression, hormonal and metabolic regulation and pharmacologic intervention.

Regulation of Ca2+-ATPases,V-ATPases and F-ATPases

Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 3319247808
Total Pages : 582 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Regulation of Ca2+-ATPases,V-ATPases and F-ATPases by : Sajal Chakraborti

Download or read book Regulation of Ca2+-ATPases,V-ATPases and F-ATPases written by Sajal Chakraborti and published by Springer. This book was released on 2015-12-10 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed virtually in all live forms starting from unicellular to multicellular and also in viruses. There are different types of ATPases, which differ in function and structure and in the type of ions they transport. The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca2+ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient; and (iii) V-type ATPase catalyzes ATP hydrolysis to transport solutes and maintains acidic pH in organelles like lysosomes. Genetic defects in either of the ATPases cause several diseases and a number of researches have demonstrated the involvement of the members of ATPases in the cell pathology and diseases, thereby penetrating exciting new areas of our understanding. In this book, the authors summarize recent knowledge about the molecular mechanisms associated with Ca2+-ATPase, V-ATPase and F-ATPase in intracellular and extracellular Ca2+ transport, mitochondrial ATP synthase, vesicular H+ transport, and lysosomal pH regulation. This book thereby bridges the gap between fundamental research and biomedical and pharmaceutical applications. The book provides an informative resource to improve ATPase research and modern therapeutic approaches toward different life threatening diseases that are associated with dysregulation of the ATPases.

The ATPases

Author : Thomas A. Pressley
Publisher : S Karger Ag
ISBN 13 : 9783805563987
Total Pages : 166 pages
Book Rating : 4.5/5 (639 download)

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Book Synopsis The ATPases by : Thomas A. Pressley

Download or read book The ATPases written by Thomas A. Pressley and published by S Karger Ag. This book was released on 1996-01-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, researchers have learned much about the regulation and structure of the ion pumps most relevant to renal function. This issue provides a comprehensive summary of current knowledge on these critical transport enzymes with particular emphasis on the kidney. The Na,K-pump is examined in six reviews which discuss structure-function relationships, expression and distribution of the pump's various forms within the nephron, its regulation by corticosteroids and the influence of second messengers on its function. Also discussed is the controversy surrounding endogenous circulating inhibitors of the Na,K-ATPase, Na,K-pump inhibition, and the pump's role in ammonium transport within the nephron. Issues relating to calcium transport mechanisms are examined in three reviews, one of which looks at the characteristics of the Ca-ATPase in vascular smooth muscle. The final section contains five reviews which address questions relating to renal acid-base balance and which seek to give new clinical insights by integrating molecular, biochemical, and histologic data.

Ecto-ATPases

Author : Liselotte Plesner
Publisher : Springer Science & Business Media
ISBN 13 : 1461559553
Total Pages : 286 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Ecto-ATPases by : Liselotte Plesner

Download or read book Ecto-ATPases written by Liselotte Plesner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the First International Workshop held in Mar de Plata, Argentina, August 26-30, 1996

Energy-Transducing ATPases - Structure and Kinetics

Author : Yuji Tonomura
Publisher : Cambridge University Press
ISBN 13 : 9780521304795
Total Pages : 318 pages
Book Rating : 4.3/5 (47 download)

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Book Synopsis Energy-Transducing ATPases - Structure and Kinetics by : Yuji Tonomura

Download or read book Energy-Transducing ATPases - Structure and Kinetics written by Yuji Tonomura and published by Cambridge University Press. This book was released on 1986-07-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Tonomura's book explains at the molecular level how cells use energy harnessed as adenosine triphosphate to perform the fundamental physiological functions such as muscle contraction and the active transport of cations. A well-written, interesting account of the structure and kinetics of energy-transducing ATPases.

Comprehensive Biophysics

Author :
Publisher : Academic Press
ISBN 13 : 0080957188
Total Pages : 3533 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Biophysics by :

Download or read book Comprehensive Biophysics written by and published by Academic Press. This book was released on 2012-04-12 with total page 3533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Na/K-ATPase and Related Transport ATPases

Author : L. Beaugé
Publisher :
ISBN 13 :
Total Pages : 720 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Na/K-ATPase and Related Transport ATPases by : L. Beaugé

Download or read book Na/K-ATPase and Related Transport ATPases written by L. Beaugé and published by . This book was released on 1997 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume disseminates the most recent advances in understanding of the molecular structure, transport mechanism, and regulatory properties of the sodium/potassium adenosine triphosphatase. Recent knowledge gained from other transport ATPases is incorporated as well. The volume also provides contributions from crystallographers, cryoelectronmicroscopists, biochemists, cell biologists, biophysicists, physiologists, and pharmacologists.

Handbook of H+-ATPases

Author : Suguru Nakamura
Publisher : CRC Press
ISBN 13 : 9814411914
Total Pages : 505 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Handbook of H+-ATPases by : Suguru Nakamura

Download or read book Handbook of H+-ATPases written by Suguru Nakamura and published by CRC Press. This book was released on 2014-03-19 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling. It also describes the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, and under diabetic conditions.

Organellar Proton-ATPases

Author : Nathan Nelson
Publisher : Springer Science & Business Media
ISBN 13 : 3662222655
Total Pages : 237 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Organellar Proton-ATPases by : Nathan Nelson

Download or read book Organellar Proton-ATPases written by Nathan Nelson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE WORLD OF PROTON PUMPS Nathan Nelson uite frequently an observer looks at a life phenomenon and asks ~himself why nature took this route out of several other available mec anisms. In order to understand this challenge he may first try to reconstruct the evolution of the process taking into account the main driving forces that were assumed to exist during the last 3. 5 billion years on earth. Now we know that the electrochemical gradient of protons is the universal high-energy intermediate produced and uti lized by every living cell in nature. This high energy intermediate is an expression of different concentrations of active protons in the two faces of biological membranes. Why then did nature elect to utilize a pre dominantly electrochemical gradient of protons and no other ion? The answer to this question may lie in the environment in which the first living creatures evolved. Some of them may have been challenged by an acidic environment that lowered their internal pH (by a proton leak through their membranes) to lethal levels. To counteract these inci dents proton pumps evolved. Two independent systems were devel oped. One was a proton pump coupled to energetically downhill vectorial electron transport across membranes and the second was an ATP-dependent proton pump. Both of them pump protons outward from the cells generating an electrochemical gradient of protons.

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

P-type ATPases in Health and Disease

Author : Sigrid A. Langhans
Publisher : Frontiers Media SA
ISBN 13 : 2889457117
Total Pages : 265 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis P-type ATPases in Health and Disease by : Sigrid A. Langhans

Download or read book P-type ATPases in Health and Disease written by Sigrid A. Langhans and published by Frontiers Media SA. This book was released on 2019-01-11 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metal Transporters

Author : Jose M. Arguello
Publisher : Academic Press
ISBN 13 : 0123943906
Total Pages : 478 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Metal Transporters by : Jose M. Arguello

Download or read book Metal Transporters written by Jose M. Arguello and published by Academic Press. This book was released on 2012-10-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise

Transport ATPases

Author : Ernesto Carafoli
Publisher :
ISBN 13 :
Total Pages : 626 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Transport ATPases by : Ernesto Carafoli

Download or read book Transport ATPases written by Ernesto Carafoli and published by . This book was released on 1982 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:

P-Type ATPases

Author : Maike Bublitz
Publisher : Humana Press
ISBN 13 : 9781493979950
Total Pages : 544 pages
Book Rating : 4.9/5 (799 download)

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Book Synopsis P-Type ATPases by : Maike Bublitz

Download or read book P-Type ATPases written by Maike Bublitz and published by Humana Press. This book was released on 2019-03-29 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a broad collection of protocols for many of the common experimental techniques used for the characterization of P-type ATPases. P-Type ATPases: Methods and Protocols provides comprehensive practical instructions for all researchers in the P-type ATPase field, from the protein biochemist to the mouse geneticist, covering the identification and classification, isolation, purification, in vitro characterization, knock-out studies, as well as crystallization and structural analysis. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, P-Type ATPases: Methods and Protocols aims to ensure successful results in the further study of this vital field of research.