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The Antibiotic Resistome
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Book Synopsis The Antibiotic Resistome by : Gerry Wright
Download or read book The Antibiotic Resistome written by Gerry Wright and published by Wiley. This book was released on 2016-08-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Antimicrobial Resistance in Wastewater Treatment Processes by : Patricia L. Keen
Download or read book Antimicrobial Resistance in Wastewater Treatment Processes written by Patricia L. Keen and published by John Wiley & Sons. This book was released on 2017-12-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial resistance is arguably the greatest threat to worldwide human health. This book evaluates the roles of human water use, treatment and conservation in the development and spread of antimicrobial resistance. Designed as a companion volume to Antimicrobial Resistance in the Environment (Wiley-Blackwell, 2012), this book is a multi-disciplinary synthesis of topics related to antimicrobial resistance and wastewater treatment processes. Antimicrobial Resistance in Wastewater Treatment Processes assembles detailed discussions written by many of the world's best-known experts in microbiology, civil engineering, chemistry, environmental science, public health and related fields. The book presents a collection of subjects that includes: Current knowledge of the role of the environment in development and spread of antimicrobial resistance Chemical analysis of antibiotics in environmental samples Molecular methods for analysis of antimicrobial resistance genes Advanced wastewater treatment processes and antimicrobial resistance effects Public perception of risk related to health consequences of antimicrobial resistance Public health implications of antimicrobial resistance with focus on wastewater treatment processes Antimicrobial resistance has gained a foothold in the global consciousness as a serious public health threat. There is a much greater appreciation for the role of the environment in the dissemination of antimicrobial resistance and the effects of pollutants that can potentially promote development of resistance in bacteria. Contaminants released from wastewater treatment plants are a concern. In Antimicrobial Resistance in Wastewater Treatment Processes, readers will be guided through examinations of the current science related to this important health issue.
Book Synopsis Antibiotic Drug Resistance by : José-Luis Capelo-Martínez
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Book Synopsis Bacterial Resistance to Antibiotics by : Boyan B. Bonev
Download or read book Bacterial Resistance to Antibiotics written by Boyan B. Bonev and published by John Wiley & Sons. This book was released on 2019-06-10 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Book Synopsis Antibiotic Resistance in Aquatic Systems by : Satoru Suzuki
Download or read book Antibiotic Resistance in Aquatic Systems written by Satoru Suzuki and published by Frontiers Media SA. This book was released on 2017-04-10 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rivers, lakes and the ocean receive antibiotic resistance genes from human environments. The aquatic environments are a huge reservoir and exchange stage of antibiotic resistance genes.
Book Synopsis WHO guidelines on use of medically important antimicrobials in food-producing animals by : World Health Organization
Download or read book WHO guidelines on use of medically important antimicrobials in food-producing animals written by World Health Organization and published by World Health Organization. This book was released on 2017-11-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.
Book Synopsis Antimicrobial Resistance in the Environment by : Patricia L. Keen
Download or read book Antimicrobial Resistance in the Environment written by Patricia L. Keen and published by John Wiley & Sons. This book was released on 2012-01-24 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystem Resistance genes are everywhere in nature—in pathogens, commensals, and environmental microorganisms. This contributed work shows how the environment plays a pivotal role in the development of antimicrobial resistance traits in bacteria and the distribution of resistant microbial species, resistant genetic material, and antibiotic compounds. Readers will discover the impact of the distribution in the environment of antimicrobial resistance genes and antibiotics on both the ecosystem and human and animal health. Antimicrobial Resistance in the Environment is divided into four parts: Part I, Sources, including ecological and clinical consequences of antibiotic resistance by environmental microbes Part II, Fate, including strategies to assess and minimize the biological risk of antibiotic resistance in the environment Part III, Antimicrobial Substances and Resistance, including antibiotics in the aquatic environment Part IV, Effects and Risks, including the effect of antimicrobials used for non-human purposes on human health Recognizing the intricate links among overlapping complex systems, this book examines antimicrobial resistance using a comprehensive ecosystem approach. Moreover, the book's multidisciplinary framework applies principles of microbiology, environmental toxicology, and chemistry to assess the human and ecological risks associated with exposure to antibiotics or antibiotic resistance genes that are environmental contaminants. Each chapter has been written by one or more leading researchers in such fields as microbiology, environmental science, ecology, and toxicology. Comprehensive reference lists at the end of all chapters serve as a gateway to the primary research in the field. Presenting and analyzing the latest findings in a field of growing importance to human and environmental health, this text offers readers new insights into the role of the environment in antimicrobial resistance development, the dissemination of antimicrobial resistant genetic elements, and the transport of antibiotic resistance genes and antibiotics.
Book Synopsis Antibiotic Resistance in the Environment by : Célia M. Manaia
Download or read book Antibiotic Resistance in the Environment written by Célia M. Manaia and published by Springer. This book was released on 2021-08-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a multidisciplinary review of antibiotic resistance and unravels the complex and interrelated roles of environmental sources, including pharmaceutical industry effluents, hospital and domestic effluents, wildlife and drinking water. Antibiotic resistance is a global public health issue in which the interface between humans, animals and the environment is particularly relevant. The contrasts seen across different environmental compartments and world regions, which are due to climate, social and policy differences, mean that this problem needs to be analyzed from a multi-geographic and multi-cultural angle. Bringing together contributions from researchers on different continents with expertise in antibiotic resistance in a range of different environmental compartments, the book offers a detailed reflection on the paths that make antibiotic resistance a global threat, and the state-of- the-art in antibiotic resistance surveillance and risk assessment in complex environmental matrices.
Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Download or read book The Pangenome written by Hervé Tettelin and published by Springer Nature. This book was released on 2020-04-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Book Synopsis Antimicrobial Therapy in Veterinary Medicine by : Steeve Giguère
Download or read book Antimicrobial Therapy in Veterinary Medicine written by Steeve Giguère and published by John Wiley & Sons. This book was released on 2013-07-25 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.
Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine
Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Book Synopsis Antimicrobial Resistance by : Mihai Mares
Download or read book Antimicrobial Resistance written by Mihai Mares and published by BoD – Books on Demand. This book was released on 2021-03-03 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.
Book Synopsis Microbial Environmental Genomics (MEG) by : Francis Martin
Download or read book Microbial Environmental Genomics (MEG) written by Francis Martin and published by Springer Nature. This book was released on 2022-12-15 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume guides researchers on how to characterize, image rare, and hitherto unknown taxa and their interactions, to identify new functions and biomolecules and to understand how environmental changes condition the activity and the response of the organisms living with us and in our environment. Chapters cover different organism types (i.e., archaea, bacteria, fungi, protest, microfauna and microeukaryotes) and propose detailed protocols to produce high quality DNA, to analyse active microbial communities directly involved in complex interactions or processes through stable isotope probing, to identify and characterize of new functional genes, to image in situ interactions and to apply bioinformatics analysis tools to complex metagenomic or RNAseq sequence data. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Microbial Environmental Genomics (MEG): Methods and Protocols, Second Edition aims to serve as a primary research reference for researchers in microbiology working to in the expanding field of molecular ecology and environmental genomics.
Download or read book Antibiotics written by Christopher Walsh and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.
Book Synopsis DNA and RNA Modification Enzymes by : Henri Grosjean
Download or read book DNA and RNA Modification Enzymes written by Henri Grosjean and published by CRC Press. This book was released on 2009-06-11 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a shortconclusion and future prospect' section and
Book Synopsis Antibiotic Resistance by : Institute of Medicine
Download or read book Antibiotic Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-10 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.