Telling Genes

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Telling Genes

Author : Alexandra Minna Stern
Publisher : JHU Press
ISBN 13 : 1421407485
Total Pages : 249 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Telling Genes by : Alexandra Minna Stern

Download or read book Telling Genes written by Alexandra Minna Stern and published by JHU Press. This book was released on 2012-11-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of contemporary genetic counseling, including its medical, personal, and ethical dimensions. Winner of the CHOICE Outstanding Academic Title of the Choice ACRL For sixty years genetic counselors have served as the messengers of important information about the risks, realities, and perceptions of genetic conditions. More than 2,500 certified genetic counselors in the United States work in clinics, community and teaching hospitals, public health departments, private biotech companies, and universities. Telling Genes considers the purpose of genetic counseling for twenty-first century families and society and places the field into its historical context. Genetic counselors educate physicians, scientific researchers, and prospective parents about the role of genetics in inherited disease. They are responsible for reliably translating test results and technical data for a diverse clientele, using scientific acumen and human empathy to help people make informed decisions about genomic medicine. Alexandra Minna Stern traces the development of genetic counseling from the eugenics movement of the early twentieth century to the current era of human genomics. Drawing from archival records, patient files, and oral histories, Stern presents the fascinating story of the growth of genetic counseling practices, principles, and professionals.

More Than Genes

Author : Dan Agin
Publisher : Oxford University Press
ISBN 13 : 0199745803
Total Pages : 414 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis More Than Genes by : Dan Agin

Download or read book More Than Genes written by Dan Agin and published by Oxford University Press. This book was released on 2009-11-02 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are all shaped by our genetic inheritance and by the environment we live in. Indeed, the argument about which of these two forces, nature or nurture, predominates has been raging for decades. But what about our very first environment--the prenatal world where we exist for nine months between conception and birth and where we are more vulnerable than at any other point in our lives? In More Than Genes, Dan Agin marshals new scientific evidence to argue that the fetal environment can be just as crucial as genetic hard-wiring or even later environment in determining our intelligence and behavior. Stress during pregnancy, for example, puts women at far greater risk of bearing children prone to anxiety disorders. Nutritional deprivation during early fetal development may elevate the risk of late onset schizophrenia. And exposure to a whole host of environmental toxins--methylmercury, polychlorinated biphenyls (PCBs), dioxins, pesticides, ionizing radiation, and most especially lead--as well as maternal use of alcohol, tobacco, marijuana, or cocaine can have impacts ranging from mild cognitive impairment to ADHD, autism, schizophrenia, and other mental disorders. Agin argues as well that differences in IQ among racial, ethnic, and socioeconomic groups are far more attributable to higher levels of stress and chemical toxicity in inner cities--which seep into the prenatal environment and compromise the health of the fetus--than to genetic inheritance. The good news is that the prenatal environment is malleable, and Agin suggests that if we can abandon the naive idea of "immaculate gestation," we can begin to protect fetal development properly. Cogently argued, thoroughly researched, and accessibly written, More Than Genes challenges many long-held assumptions and represents a huge step forward in our understanding of the origins of human intelligence and behavior.

Disability Dialogues

Author : Andrew J. Hogan
Publisher : JHU Press
ISBN 13 : 1421445344
Total Pages : 263 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Disability Dialogues by : Andrew J. Hogan

Download or read book Disability Dialogues written by Andrew J. Hogan and published by JHU Press. This book was released on 2022-11-29 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: A historical look at how activists influenced the adoption of more positive, inclusive, and sociopolitical views of disability. Disability activism has fundamentally changed American society for the better—and along with it, the views and practices of many clinical professionals. After 1945, disability self-advocates and family advocates pushed for the inclusion of more positive, inclusive, and sociopolitical perspectives on disability in clinical research, training, and practice. In Disability Dialogues, Andrew J. Hogan highlights the contributions of disabled people—along with their family members and other allies—in changing clinical understandings and approaches to disability. Hogan examines the evolving medical, social, and political engagement of three postwar professions—clinical psychology, pediatrics, and genetic counseling—with disability and disability-related advocacy. Professionals in these fields historically resisted adopting a more inclusive and accepting perspective on people with disabilities primarily due to concerns about professional role, identity, and prestige. In response to the work of disability activists, however, these attitudes gradually began to change. Disability Dialogues provides an important contribution to historical, sociological, and bioethical accounts of disability and clinical professionalization. Moving beyond advocacy alone, Hogan makes the case for why present-day clinical professional fields need to better recruit and support disabled practitioners. Disabled clinicians are uniquely positioned to combine biomedical expertise with their lived experiences of disability and encourage greater tolerance for disabilities among their colleagues, students, and institutions.

Evolutionary Pathways in Nature

Author : John C. Avise
Publisher : Cambridge University Press
ISBN 13 : 1139455036
Total Pages : 17 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Evolutionary Pathways in Nature by : John C. Avise

Download or read book Evolutionary Pathways in Nature written by John C. Avise and published by Cambridge University Press. This book was released on 2006-05-04 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reconstructing phylogenetic trees from DNA sequences has become a popular exercise in many branches of biology, and here the well-known geneticist John Avise explains why. Molecular phylogenies provide a genealogical backdrop for interpreting the evolutionary histories of many other types of biological traits (anatomical, behavioral, ecological, physiological, biochemical and even geographical). Guiding readers on a natural history tour along dozens of evolutionary pathways, the author describes how creatures ranging from microbes to elephants came to possess their current phenotypes. Essential reading for college students, professional biologists and anyone interested in natural history and biodiversity, this book is packed with fascinating examples of evolutionary puzzles from across the animal kingdom; how the toucan got its enormous bill, how reptiles grow back lost limbs and why Arctic fish don't freeze.

Making Genes, Making Waves

Author : Jon Beckwith
Publisher : Harvard University Press
ISBN 13 : 0674020677
Total Pages : 251 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Making Genes, Making Waves by : Jon Beckwith

Download or read book Making Genes, Making Waves written by Jon Beckwith and published by Harvard University Press. This book was released on 2009-07-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.

The Genome War

Author : James Shreeve
Publisher : Ballantine Books
ISBN 13 : 0307417069
Total Pages : 418 pages
Book Rating : 4.3/5 (74 download)

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Book Synopsis The Genome War by : James Shreeve

Download or read book The Genome War written by James Shreeve and published by Ballantine Books. This book was released on 2007-12-18 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-awaited story of the science, the business, the politics, the intrigue behind the scenes of the most ferocious competition in the history of modern science—the race to map the human genome. On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life—seven years before the projected finish of the U.S. government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work. At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.

Life Histories of Genetic Disease

Author : Andrew J. Hogan
Publisher : Johns Hopkins University Press+ORM
ISBN 13 : 1421420759
Total Pages : 264 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Life Histories of Genetic Disease by : Andrew J. Hogan

Download or read book Life Histories of Genetic Disease written by Andrew J. Hogan and published by Johns Hopkins University Press+ORM. This book was released on 2016-10-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A richly detailed history that “uncovers the challenges and limitations of our increasing reliance on genetic data in medical decision making” (Shobita Parthasarathy, author of Building Genetic Medicine). Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing expectant parents to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In this book, Andrew J. Hogan explores how various diseases were “made genetic” after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly “big data”–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation. Hogan critiques the modern ideology of genetic prevention, which suggests all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies offer whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.

Genetic Testing and Gene Therapy

Author : James Wolfe
Publisher : Encyclopaedia Britannica
ISBN 13 : 1622755731
Total Pages : 128 pages
Book Rating : 4.6/5 (227 download)

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Book Synopsis Genetic Testing and Gene Therapy by : James Wolfe

Download or read book Genetic Testing and Gene Therapy written by James Wolfe and published by Encyclopaedia Britannica. This book was released on 2015-07-15 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the foundations of genes and heredity to give readers a solid understanding of what modern genetics has been built on, before examining the ways in which genetic testing is used to assess genetic risk.

Genetics as Social Practice

Author : Dr Barbara Prainsack
Publisher : Ashgate Publishing, Ltd.
ISBN 13 : 1472407180
Total Pages : 240 pages
Book Rating : 4.4/5 (724 download)

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Book Synopsis Genetics as Social Practice by : Dr Barbara Prainsack

Download or read book Genetics as Social Practice written by Dr Barbara Prainsack and published by Ashgate Publishing, Ltd.. This book was released on 2014-03-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent debate about the ethical and regulatory dimensions of developments in genetics has sidelined societal and cultural aspects, which arguably are indispensable for a nuanced understanding of the complexities of the topic. Regulatory and ethical debates benefit from taking seriously this ‘third dimension’ of culture, which often determines the configurations and limits of the space within which scientific, ethical and legal debate can take place. To fill this gap, this volume brings together contributions exploring the mutual relationships between genetics, markets, societies and identities in genetics and genomics. It draws upon the recent transdisciplinary debate on how socio-cultural factors influence understandings of ‘genetics2.0' and shows how individual and collective identities are challenged or reinforced by cultural meanings and practices of genetics. This book will become a standard reference for everyone seeking to make sense of the controversies and shifts in the field of genetics in the second decade of the twenty-first century.

Advanced Genetic Counseling

Author : Barbara B. Biesecker
Publisher : Oxford University Press, USA
ISBN 13 : 0190626429
Total Pages : 241 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Advanced Genetic Counseling by : Barbara B. Biesecker

Download or read book Advanced Genetic Counseling written by Barbara B. Biesecker and published by Oxford University Press, USA. This book was released on 2019 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: A CRITICAL NEW APPROACH FOR LEARNING AND THRIVING IN A FIELD OF CHANGE The scope and responsibilities of today's genetic counselors exceed the reasonable capacity of any one educational resource. While the field's first-year curriculum may be relatively fixed, the landscape of what comes after that -- a dizzying mix of practice, ethics, research design, and professional competencies -- is increasingly broad. Advanced Genetic Counseling offers an overdue extension of the field's core curriculum. From navigating ethical dilemmas and potential conflicts of interest to confronting the biases and patterns of thought that can limit counselors' interactions with clients, it prepares readers to face the profession's most challenging aspects with confidence. Drawing on techniques from psychotherapy, social psychology, and health behavior, Advanced Genetic Counseling is an essential resource for trainees and mid-career professionals. It offers a roadmap not just for addressing client needs, but for the future of genetic counseling education.

The Science of Human Perfection

Author : Nathaniel Comfort
Publisher : Yale University Press
ISBN 13 : 0300169914
Total Pages : 336 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis The Science of Human Perfection by : Nathaniel Comfort

Download or read book The Science of Human Perfection written by Nathaniel Comfort and published by Yale University Press. This book was released on 2012-09-25 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thoughtful new look at the entwined histories of genetic medicine and eugenics, with probing discussion of the moral risks of seeking human perfection

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Author : Sorin Hostiuc
Publisher : Elsevier
ISBN 13 : 0443190461
Total Pages : 556 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies by : Sorin Hostiuc

Download or read book Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies written by Sorin Hostiuc and published by Elsevier. This book was released on 2023-08-14 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy. This second edition of Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers a thorough, timely discussion of ethical issues raised by the latest genetic and genomic technologies applied in human reproductive and prenatal medicine, providing practical recommendations, guidelines, and algorithms to support ethical clinical practice. Here, international experts consider the ethics of technologies from preconception carrier screening to genetic engineering, CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction, and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Throughout the book, contributors adopt a global, holistic perspective on applied challenges and the moral questions around the implementation of genetic reproductive technologies. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors, and graduate and medical students.This fully updated second edition examines new developments in the field, tackling ethical aspects of organoid development, recent advances in pharmacogenomics, direct-to-consumer genetic testing, and genetic engineering. • Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive geneticsContains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology • Discusses preconception carrier screening, genetic engineering, and the use of CRISPR gene editing, mitochondrial gene replacement therapy, and ethical issues, among others • Considers ethical aspects of recent advances and new technologies in the field, from organoid development to pharmacogenomics and direct-to-consumer genetic testing

Tyranny of the Gene

Author : James Tabery
Publisher : Knopf
ISBN 13 : 0525658211
Total Pages : 337 pages
Book Rating : 4.5/5 (256 download)

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Book Synopsis Tyranny of the Gene by : James Tabery

Download or read book Tyranny of the Gene written by James Tabery and published by Knopf. This book was released on 2023-08-15 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicine The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen. In Tyranny of the Gene, James Tabery exposes the origin story of personalized medicine—essentially a marketing idea dreamed up by pharmaceutical executives—and traces its path from the Human Genome Project to the present, revealing how politicians, influential federal scientists, biotech companies, and drug giants all rallied behind the genetic hype. The result is a medical revolution that privileges the few at the expense of health care that benefits us all. Now American health care, driven by the commercialization of biomedical research, is shifting focus away from the study of the social and environmental determinants of health, such as access to fresh and nutritious food, exposure to toxic chemicals, and stress caused by financial insecurity. Instead, it is increasingly investing in “miracle pills” for leukemia that would bankrupt most users, genetic studies of minoritized populations that ignore structural racism and walk dangerously close to eugenic conclusions, and oncology centers that advertise the perfect gene-drug match, igniting a patient’s hope, and often dashing it later.Tyranny of the Gene sounds a warning cry about the current trajectory of health care and charts a path to a more equitable alternative.

The Language of Genes

Author : Steve Jones
Publisher : Anchor
ISBN 13 : 0385474288
Total Pages : 274 pages
Book Rating : 4.3/5 (854 download)

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Book Synopsis The Language of Genes by : Steve Jones

Download or read book The Language of Genes written by Steve Jones and published by Anchor. This book was released on 1995-06-01 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Did you know that two of every three people reading this book will die for reasons connected with the genes they carry? That our DNA gradually changes with age, which is why older parents are more likely to give birth to children with genetic defects than younger parents? That each individual is a kind of living fossil, carrying within a genetic record that goes back to the beginnings of humanity? In The Language of Genes, renowned geneticist Steve Jones explores the meanings and explodes the myths of human genetics, offering up an extraordinary picture of what we are, what we were, and what we may become. “An essential book for anyone interested in the development and possible future of our species.”—Kirkus Reviews “This is one of the most insightful books on genetics to date and certainly the most entertaining.”—The Wall Street Journal

The Oxford Handbook of Disability History

Author : Michael Rembis
Publisher : Oxford University Press
ISBN 13 : 0190234962
Total Pages : 640 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The Oxford Handbook of Disability History by : Michael Rembis

Download or read book The Oxford Handbook of Disability History written by Michael Rembis and published by Oxford University Press. This book was released on 2018-06-19 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disability history exists outside of the institutions, healers, and treatments it often brings to mind. It is a history where disabled people live not just as patients or cure-seekers, but rather as people living differently in the world--and it is also a history that helps define the fundamental concepts of identity, community, citizenship, and normality. The Oxford Handbook of Disability History is the first volume of its kind to represent this history and its global scale, from ancient Greece to British West Africa. The twenty-seven articles, written by thirty experts from across the field, capture the diversity and liveliness of this emerging scholarship. Whether discussing disability in modern Chinese cinema or on the American antebellum stage, this collection provides new and valuable insights into the rich and varied lives of disabled people across time and place.

Fables and Futures

Author : George Estreich
Publisher : MIT Press
ISBN 13 : 0262351803
Total Pages : 239 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Fables and Futures by : George Estreich

Download or read book Fables and Futures written by George Estreich and published by MIT Press. This book was released on 2019-03-19 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.

Eradicating deafness?

Author : Marion Andrea Schmidt
Publisher : Manchester University Press
ISBN 13 : 1526138190
Total Pages : 277 pages
Book Rating : 4.5/5 (261 download)

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Book Synopsis Eradicating deafness? by : Marion Andrea Schmidt

Download or read book Eradicating deafness? written by Marion Andrea Schmidt and published by Manchester University Press. This book was released on 2020-04-20 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did American geneticists go from fearing the dysgenic effects of deaf intermarriage to considering modern biotechnology a threat for Deaf culture? This book provides insight into changing ideas of what deafness is, what science and medicine should achieve, and to the transformative effect of exchange between scientists and deaf communities.