Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases

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Publisher : Bentham Science Publishers
ISBN 13 : 9815124498
Total Pages : 344 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases by : Reza Heidari

Download or read book Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases written by Reza Heidari and published by Bentham Science Publishers. This book was released on 2023-03-31 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taurine, or 2aminoethanesulfonic acid, is one of the most abundant sulfurcontaining amino acids in the human body. It is found in the heart, brain, retina, and skeletal muscles, and is synthesized in the pancreas. Studies have revealed that taurine is of high physiological importance: it protects against pathologies associated with mitochondrial diseases, and linked processes like aging, metabolic syndrome, cancer, cardiovascular diseases, and neurological disorders. It is also used as a nutritional supplement. Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases explores the significance of taurine in the biology of mitochondria. It also explains its role as a pharmacological agent for treating different diseases. Readers will gain an insight into the crucial role it plays in human physiology and the benefits of taurine supplements. Topics covered in this reference include Synthesis of taurine and its dietary sources The Role of taurine in mitochondrial health Taurine as a neurotransmitter Beneficial effects of taurine in physiological systems such as the reproductive system, renal system, and the gastrointestinal tract Hepatoprotective and antiinflammatory properties of taurine The antiaging promise of taurine supplementation Role of taurine supplementation in obesity

Glutathione and Sulfur Amino Acids in Human Health and Disease

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Publisher : John Wiley & Sons
ISBN 13 : 047047596X
Total Pages : 626 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Glutathione and Sulfur Amino Acids in Human Health and Disease by : Roberta Masella

Download or read book Glutathione and Sulfur Amino Acids in Human Health and Disease written by Roberta Masella and published by John Wiley & Sons. This book was released on 2009-08-06 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. The twenty-two chapters explore such topics as: Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models. With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.

Principles and Applications of Molecular Diagnostics

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Publisher : Elsevier
ISBN 13 : 0128160624
Total Pages : 424 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles and Applications of Molecular Diagnostics by : Nader Rifai

Download or read book Principles and Applications of Molecular Diagnostics written by Nader Rifai and published by Elsevier. This book was released on 2018-06-13 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. - Explains the principles and tools of molecular biology - Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results - Provides a detailed description of current molecular applications used to solve diagnostics tasks

Mitochondrial Metabolism

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Publisher : Academic Press
ISBN 13 : 0128224096
Total Pages : 318 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Mitochondrial Metabolism by : Jalal Pourahmad

Download or read book Mitochondrial Metabolism written by Jalal Pourahmad and published by Academic Press. This book was released on 2021-07-28 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more. This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders. - Details the significant role of mitochondria in chronic diseases - Presents new insights on the targeting of mitochondria for therapeutic purposes - Includes updated results on mitotherapy and other mitochondria-oriented therapies

Taurine 5

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Publisher : Springer Science & Business Media
ISBN 13 : 146150077X
Total Pages : 574 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Taurine 5 by : John B. Lombardini

Download or read book Taurine 5 written by John B. Lombardini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.

Taurine 9

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Publisher : Springer
ISBN 13 : 3319151266
Total Pages : 880 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Taurine 9 by : Janusz Marcinkiewicz

Download or read book Taurine 9 written by Janusz Marcinkiewicz and published by Springer. This book was released on 2015-04-01 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May 2014. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.

Mitochondrial Dysfunction

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Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Taurine 10

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Publisher : Springer
ISBN 13 : 9402410791
Total Pages : 1181 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Taurine 10 by : Dong-Hee Lee

Download or read book Taurine 10 written by Dong-Hee Lee and published by Springer. This book was released on 2017-08-28 with total page 1181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.

Mitochondrial Medicine

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Publisher :
ISBN 13 : 9789081773706
Total Pages : 135 pages
Book Rating : 4.7/5 (737 download)

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Book Synopsis Mitochondrial Medicine by : Saskia Koene

Download or read book Mitochondrial Medicine written by Saskia Koene and published by . This book was released on 2011 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clostridium Difficile

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Publisher :
ISBN 13 : 9781493963614
Total Pages : 292 pages
Book Rating : 4.9/5 (636 download)

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Book Synopsis Clostridium Difficile by : Adam P. Roberts

Download or read book Clostridium Difficile written by Adam P. Roberts and published by . This book was released on 2016 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This second edition provides 21 new chapters on methods used in laboratories for investigating the physiology and molecular genetics of the pathogen Clostridium difficile. Chapters detail up-to -date experimental techniques for gene editing and transcriptional analysis which are used to investigate the fundamental biology of the organism and its virulence factors. Additional chapters describe development of potential new treatments including vaccines, bacteriophage and faecal transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Clostridium difficile: Methods and Protocols, Second Edition provides a comprehensive catalogue of molecular tools and techniques authored by the researchers who have developed them." -- OCLC.

Mitochondrial Transplantation and Transfer

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Publisher : Elsevier
ISBN 13 : 0443188599
Total Pages : 562 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Mitochondrial Transplantation and Transfer by : Gokhan Burcin Kubat

Download or read book Mitochondrial Transplantation and Transfer written by Gokhan Burcin Kubat and published by Elsevier. This book was released on 2024-08-03 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases, among other disease types. Step-by-step instruction is provided around research protocols and methods discussed, along with careful attention to the ethical implications of mitochondrial transplantation research and application. - Provides an in-depth discussion of mitochondrial transplantation, considering fundamental biology, disease implications, research methods and applications - Discusses recent advances in the field and their meaning for future research and clinical utility - Considers ethical dimensions of mitochondrial transplantation research and use in therapeutics - Examines mitochondrial transplantation across a range of disease types, from neurological to cardiovascular disease and ischemia

Liver Disease in Children

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Publisher : Cambridge University Press
ISBN 13 : 1139464035
Total Pages : 995 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Liver Disease in Children by : Frederick J. Suchy

Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2007-05-07 with total page 995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Taurine

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Publisher : Plenum Publishing Corporation
ISBN 13 : 9780306442247
Total Pages : 456 pages
Book Rating : 4.4/5 (422 download)

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Book Synopsis Taurine by : J. Barry Lombardini

Download or read book Taurine written by J. Barry Lombardini and published by Plenum Publishing Corporation. This book was released on 1992 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Waltham Symposium on Taurine and Cat Nutrition, held October 1991, and of the International Taurine Symposium: New Dimensions on its Mechanisms of Action, held October 1991, in Orange Beach, Alabama. The single biggest factor in elucidating the many functions of taurine in the las

Evaluation of Environmental Contaminants and Natural Products: A Human Health Perspective

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Publisher : Bentham Science Publishers
ISBN 13 : 981141095X
Total Pages : 296 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Evaluation of Environmental Contaminants and Natural Products: A Human Health Perspective by : Ashita Sharma

Download or read book Evaluation of Environmental Contaminants and Natural Products: A Human Health Perspective written by Ashita Sharma and published by Bentham Science Publishers. This book was released on 2019-06-10 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unbridled urbanization and development of natural land resources has led to the degradation of our surrounding environment. The air that we breathe, the water we drink and the food we eat is at risk of being contaminated with a plethora of chemical pollutants, some of them being potentially carcinogenic. This presents a challenge to human health. This book attempts to address this challenge in two parts which represent two different approaches. The first part of the book summarizes the alarming effects of environmental contaminants. Various studies depicting the direct relationship of environmental contaminants with cancer incidence have been referenced. Scientific studies have established an inverse relation between cancer and ingestion of dietary phytoconstituents (phytochemicals) in the form of fruits, vegetables and botanical herbs. Plant products as dietary supplements can suppress contaminant toxicity by regulating the resulting reactive species and also by assisting their bodily excretion through Phase 1 and Phase 2 enzyme metabolism. The second part of the book, shifts focus to phytoconstituents which, if included in diet, can prevent the harmful effects of pollutants. The text references numerous studies showing the anti-mutagenic, anti-genotoxic and anti-carcinogenic potential of many plant products. The combination of information about contemporary issues of carcinogenic contaminants in the environment coupled with the references to relevant studies in this handbook will enlighten readers studying courses in environmental chemistry, toxicology, botany, and ecology about environmental toxins and help them understand specific dietary measures known to reduce the toxic impact. Researchers in the field of nutrition can also benefit from the information provided.

Hemolymph Proteins and Functional Peptides

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Publisher : Bentham Science Publishers
ISBN 13 : 1608054012
Total Pages : 191 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Hemolymph Proteins and Functional Peptides by : Muhammad Tufail

Download or read book Hemolymph Proteins and Functional Peptides written by Muhammad Tufail and published by Bentham Science Publishers. This book was released on 2012 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent molecular studies have revealed an overwhelming role of hemolymph proteins and functional peptides in invertebrate physiology. This is mainly due to the large assortment of biomolecular factors each with a different structure and function. In addit

Mitochondrial Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1402067143
Total Pages : 446 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mitochondrial Medicine by : Anna Gvozdjáková

Download or read book Mitochondrial Medicine written by Anna Gvozdjáková and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. This book is based on extensive data gathered over 30 years of clinical and experimental research. In it, internationally recognized authors share their experience in various fields of their expertise and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.

The Biochemistry of the Grape Berry

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Publisher : Bentham Science Publishers
ISBN 13 : 1608053601
Total Pages : 304 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis The Biochemistry of the Grape Berry by : Hernâni Gerós

Download or read book The Biochemistry of the Grape Berry written by Hernâni Gerós and published by Bentham Science Publishers. This book was released on 2012 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Grapes (Vitis spp.) are economically significant fruit species. Many scientific advances have been achieved in understanding physiological, biochemical, and molecular aspects of grape berry maturation. Some of these advances have led to the improvement of"