Targeted Photodynamic Therapy For Improved Lung Cancer Treatment

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Targeted Photodynamic Therapy for Improved Lung Cancer Treatment

Author : Anine Crous
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)

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Book Synopsis Targeted Photodynamic Therapy for Improved Lung Cancer Treatment by : Anine Crous

Download or read book Targeted Photodynamic Therapy for Improved Lung Cancer Treatment written by Anine Crous and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer develops from the outgrowth of a clonal population of cells with a genetic pathology to evade cell death and exponential proliferation. It has become a global burden with increasing mortality rates. Lung cancer is a major contributor to cancer fatalities. Conventional therapies have shown advances in treating lung cancer, but the successful eradication of cancer lies in targeting both cancer and cancer stem cells. Cancer stem cells (CSCs) are a ration of cells found within the tumour bulk, capable of cancer initiation, therapy resistance, metastasis and cancer relapse. Photodynamic therapy (PDT) has proven effective in treating lung cancer. PDT exerts selective cell death mechanisms toward cancerous cells. With the use of a photosensitizer (PS) which becomes excited upon irradiation with laser light at a specific wavelength, the PS forms reactive oxygen species (ROS) in turn killing neoplastic cells. Leading therapeutic sequel can be obtained by transcending PDT though combination therapies such as immunotherapy and nanotechnology which will enable PDT to target lung CSCs preventing lung cancer recurrence.

Handbook of Biomedical Optics

Author : David A. Boas
Publisher : CRC Press
ISBN 13 : 1420090372
Total Pages : 816 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Biomedical Optics by : David A. Boas

Download or read book Handbook of Biomedical Optics written by David A. Boas and published by CRC Press. This book was released on 2016-04-19 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental

Resistance to Photodynamic Therapy in Cancer

Author : Valentina Rapozzi
Publisher : Springer
ISBN 13 : 3319127306
Total Pages : 253 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Resistance to Photodynamic Therapy in Cancer by : Valentina Rapozzi

Download or read book Resistance to Photodynamic Therapy in Cancer written by Valentina Rapozzi and published by Springer. This book was released on 2014-12-11 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.

Breast Cancer and Surgery

Author : Nilufer Bulut
Publisher : BoD – Books on Demand
ISBN 13 : 1789235669
Total Pages : 228 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Breast Cancer and Surgery by : Nilufer Bulut

Download or read book Breast Cancer and Surgery written by Nilufer Bulut and published by BoD – Books on Demand. This book was released on 2018-11-21 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book 'Breast Cancer and Surgery' summarizes the treatment options from the onset of breast carcinogenesis to early-local advanced and metastatic breast cancer. Chemotherapy alternatives, drug resistance and local and surgical treatment preferences are extensively discussed and this information is especially directed at clinicians, researchers, and students. This book includes a comparison between different chemotherapy agents and targeted therapies with published phase II-III studies. The importance of palliative care and dietary supplements administered during the treatment course in reducing the comorbidity of patients is emphasized. Photodynamic treatments have been included in this book. A comprehensive and up-to-date information exchange that can be accessed through a single source is provided to all researchers interested in breast cancer.

Advances in Photodynamic Therapy

Author : Michael R. Hamblin
Publisher : Artech House
ISBN 13 : 1596932783
Total Pages : 601 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis Advances in Photodynamic Therapy by : Michael R. Hamblin

Download or read book Advances in Photodynamic Therapy written by Michael R. Hamblin and published by Artech House. This book was released on 2008 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.

Respiratory Endoscopy

Author : Takehiro Izumo
Publisher : Springer
ISBN 13 : 9812879161
Total Pages : 251 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Respiratory Endoscopy by : Takehiro Izumo

Download or read book Respiratory Endoscopy written by Takehiro Izumo and published by Springer. This book was released on 2016-11-08 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed overview of the latest innovations in respiratory endoscopy, from both diagnostic and therapeutic perspectives; each chapter focuses on one disease and the techniques for early diagnosis as well as treatment. It comprehensively covers treatment and procedures, including simultaneous X-ray fluoroscopy and its use during bronchoscopic procedures. This fast-developing technology is essential for the medical management of non-malignant and malignant diseases of the chest, especially lung cancer. Respiratory Endoscopy describes the cooperation between all the members of the healthcare team, and as such is a valuable resource not only for medical staff, but also for radiological technicians and nursing staff who contribute significantly in the care of the patients undergoing these invasive procedures. By promoting teamwork and providing practical know-how, it will improve the success and safety of respiratory endoscopy procedures.

Lung Cancer

Author : Alba Fabiola Costa Torres
Publisher : BoD – Books on Demand
ISBN 13 : 1789843499
Total Pages : 206 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Lung Cancer by : Alba Fabiola Costa Torres

Download or read book Lung Cancer written by Alba Fabiola Costa Torres and published by BoD – Books on Demand. This book was released on 2018-10-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.

Nanopharmaceuticals: Principles and Applications Vol. 3

Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 3 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Photodynamic Medicine

Author : Herwig Kostron
Publisher : Royal Society of Chemistry
ISBN 13 : 1782624511
Total Pages : 680 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Photodynamic Medicine by : Herwig Kostron

Download or read book Photodynamic Medicine written by Herwig Kostron and published by Royal Society of Chemistry. This book was released on 2016 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Series in Photochemical and Photobiological Sciences. Photodynamic therapy (PDT) is increasingly being used amongst health practitioners in combating a variety of disease. This book reviews the current state of development of PDT, and also presents the foreseeable advancements of the field in the next decade. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find this book an invaluable source of information. Chapters are drawn from research discusses at the 10th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice in Brixen and are written and edited by leaders in the field. Mirroring the philosophy of that meeting, this book contains an informative balance of the basic sciences and clinical applications of PDT. Following an introduction to PDT, its history, and how techniques have developed, chapter serve as a practical guide for practitioners, covering topics such as sensitizer dosage and light dosage, and examples of relevant studies. The text goes further tp explore areas outside the medical field, such as the impact of PDT on society and the environment, and the economics of therapies. This book is dedicated to the memory of Professor Giulio Jori, and expert in this field, who sadly passed away on the 23rd December 2014.

Lasers for Medical Applications

Author : Helena Jelínková
Publisher : Elsevier
ISBN 13 : 0857097547
Total Pages : 827 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Lasers for Medical Applications by : Helena Jelínková

Download or read book Lasers for Medical Applications written by Helena Jelínková and published by Elsevier. This book was released on 2013-09-30 with total page 827 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasers have a wide and growing range of applications in medicine. Lasers for Medical Applications summarises the wealth of recent research on the principles, technologies and application of lasers in diagnostics, therapy and surgery. Part one gives an overview of the use of lasers in medicine, key principles of lasers and radiation interactions with tissue. To understand the wide diversity and therefore the large possible choice of these devices for a specific diagnosis or treatment, the respective types of the laser (solid state, gas, dye, and semiconductor) are reviewed in part two. Part three describes diagnostic laser methods, for example optical coherence tomography, spectroscopy, optical biopsy, and time-resolved fluorescence polarization spectroscopy. Those methods help doctors to refine the scope of involvement of the particular body part or, for example, to specify the extent of a tumor. Part four concentrates on the therapeutic applications of laser radiation in particular branches of medicine, including ophthalmology, dermatology, cardiology, urology, gynecology, otorhinolaryngology (ORL), neurology, dentistry, orthopaedic surgery and cancer therapy, as well as laser coatings of implants. The final chapter includes the safety precautions with which the staff working with laser instruments must be familiar. With its distinguished editor and international team of contributors, this important book summarizes international achievements in the field of laser applications in medicine in the past 50 years. It provides a valuable contribution to laser medicine by outstanding experts in medicine and engineering. Describes the interaction of laser light with tissue Reviews every type of laser used in medicine: solid state, gas, dye and semiconductor Describes the use of lasers for diagnostics

Photodynamic Therapy

Author : Thierry Patrice
Publisher : Royal Society of Chemistry
ISBN 13 : 1847551653
Total Pages : 292 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Photodynamic Therapy by : Thierry Patrice

Download or read book Photodynamic Therapy written by Thierry Patrice and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, light has been used to cure various diseases. However, it is only recently that a new medical field has arisen. Photodynamic therapy (PDT), also known as photochemotherapy, is a fast growing technique which was initially devoted to cancer care but which is now recognised as a promising treatment technique in a variety of clinical fields. Written by recognised experts, Photodynamic Therapy provides a comprehensive explanation of what PDT is and how it has developed as a technique in areas such as the detection of lung cancer and applications in dermatology, gynaecology and neurosurgery. This book is ideal both as an introduction to PDT and as an informative text for those wishing to expand their knowledge. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find it an invaluable source of information.

Advances in Radiation Oncology in Lung Cancer

Author : Branislav Jeremic
Publisher : Springer Science & Business Media
ISBN 13 : 3642199259
Total Pages : 824 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Advances in Radiation Oncology in Lung Cancer by : Branislav Jeremic

Download or read book Advances in Radiation Oncology in Lung Cancer written by Branislav Jeremic and published by Springer Science & Business Media. This book was released on 2011-09-18 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings. The first three sections cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including IMRT, IMAT, cyber knife treatment, and tomotherapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer.

Photodynamic Therapy (PDT)

Author : Flora Fitzgerald
Publisher : Nova Biomedical Books
ISBN 13 : 9781536119121
Total Pages : 0 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Photodynamic Therapy (PDT) by : Flora Fitzgerald

Download or read book Photodynamic Therapy (PDT) written by Flora Fitzgerald and published by Nova Biomedical Books. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a new concept of cancer treatment, photodynamic therapy (PDT) has gained great attention in the last few decades. Compared to classical treatments such as surgery, chemotherapy and radiotherapy, PDT is a noninvasive, localized treatment of lesions that shows fewer side effects and has low systemic toxicity. In Chapter One, the basic mechanisms, applications and functional nanomaterials-based drug delivery systems for photodynamic therapy of cancer are reviewed. Chapter Two summarizes the application of different carbon based nanomaterials as agents for PDT and discusses current state-of-the-art use of fullerenes and their derivatives, carbon nanotubes and graphene quantum dots in PDT. Chapter Three covers the benefits and pitfalls of using chemi- and bioluminescent systems as intracellular excitation sources in PDT. Bioluminescence is a widespread natural phenomenon, which consists on emission of light resulting from the oxidation of a substrate in a reaction catalyzed by an enzyme in a biological system. Chapter Four addresses in the synthesis, characterization, and photodynamic activity of a novel hydrophobic photosensitizer 5,10,15,20-tetrakis(benzo[b]thiophene) Porphyrin (BTP) and water soluble photosensitizer 5,10,15,20-Tetrakis(7- sulfonatobenzo[b]thiophene) Porphyrin (SBTP). The authors lab is engaged in the synthesis of PDT molecules incorporating benzothiophene moiety to the meso-position of porphyrin molecules. Chapter Five discusses the Guidelines for Gastroenterological Endoscopy in Patients on Oral Antithrombotic Treatment established by the Japan Gastroenterological Endoscopy Society (JGES).These guidelines classify endoscopic interventions according to the risk of hemorrhage and specify the management of various antithrombotic drugs. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are classified as high-risk procedures for hemorrhage, but PDT is not included in the guidelines. Because PDT causes ischemic necrosis of tumor tissue, the authors say this could possibly be performed safely in patients on oral antithrombotic therapy. The authors of Chapter Six developed a method of the initial concentration of protoporphyrin-IX in the operated removing glioblastoma tissue using the calibration curve of the fluorescent intensity and the known Pp-IX concentration in order to estimate of the more correlated with the cure rate.

Malignant Pleural Mesothelioma

Author : Ken O'Byrne
Publisher :
ISBN 13 : 0198529309
Total Pages : 475 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Malignant Pleural Mesothelioma by : Ken O'Byrne

Download or read book Malignant Pleural Mesothelioma written by Ken O'Byrne and published by . This book was released on 2006 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides health professionals and scientists with a comprehensive overview of the mesothelioma - an asbestos induced malignancy. It includes chapters on epidemology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, and radiotherapy as well as the molecular biology and future therapies.

Endobronchial Ultrasonography

Author : Noriaki Kurimoto
Publisher : John Wiley & Sons
ISBN 13 : 1444347845
Total Pages : 400 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Endobronchial Ultrasonography by : Noriaki Kurimoto

Download or read book Endobronchial Ultrasonography written by Noriaki Kurimoto and published by John Wiley & Sons. This book was released on 2011-07-05 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endobronchial ultrasonography (EBUS) is an exciting new diagnostic tool that has added significantly to the diagnosis and staging of lung cancer and other thoracic diseases. This book is co-authored by one of the technology's pioneers and will help the reader to use EBUS to diagnose and stage lung cancer and a variety of different tumours of the chest region. Endobronchial Ultrasonography covers all of the standard techniques and the new developments involved in EBUS as it combines two common procedures, bronchoscopy and real-time ultrasonography. This allows physicians to obtain precise biopsies of lymph nodes and masses within the chest cavity. Over 250 high quality colour digital images are featured throughout the book to illustrate the different applications of EBUS, complemented by specific case studies. This book is accompanied by a companion website featuring over 30 video clips cited in the text.

NanoBioMedicine

Author : Shailendra K. Saxena
Publisher : Springer Nature
ISBN 13 : 9813298987
Total Pages : 510 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis NanoBioMedicine by : Shailendra K. Saxena

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Cell Surface Proteases

Author :
Publisher : Elsevier
ISBN 13 : 0080490883
Total Pages : 475 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Cell Surface Proteases by :

Download or read book Cell Surface Proteases written by and published by Elsevier. This book was released on 2003-05-03 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules. Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource. * Provides an overview of the entire field of cell surface proteases in a single volume* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine * A thematic volume in the longest-running forum for contemporary issues in developmental biology with over 30 years of coverage