Systems Immunology

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Single Cell Sequencing and Systems Immunology

Author : Xiangdong Wang
Publisher : Springer
ISBN 13 : 9401797536
Total Pages : 177 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Single Cell Sequencing and Systems Immunology by : Xiangdong Wang

Download or read book Single Cell Sequencing and Systems Immunology written by Xiangdong Wang and published by Springer. This book was released on 2015-03-27 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systems Immunology and Infection Microbiology

Author : Bor-Sen Chen
Publisher : Academic Press
ISBN 13 : 0128173351
Total Pages : 673 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Systems Immunology and Infection Microbiology by : Bor-Sen Chen

Download or read book Systems Immunology and Infection Microbiology written by Bor-Sen Chen and published by Academic Press. This book was released on 2021-03-16 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate development procedures and help users understand the results of systems immunology and infection microbiology. Chapters discuss systems immunology, systems infection microbiology, systematic inflammation and immune responses in restoration and regeneration process, systems' innate and adaptive immunity in infection process, systematic genetic and epigenetic pathogenic/defensive mechanism during bacterial infection on human cells is introduced, and the systematic genetic and epigenetic pathogenic/defensive mechanisms during viral infection on human cells. This book provides new big data-driven and systems-driven systems immunology and infection microbiology to researchers applying systems biology and bioinformatics in their work. It is also invaluable to several members of biomedical field who are interested in learning more about those approaches. Encompasses one applicable example in every chapter to illustrate the solution procedure from big data mining, network modeling, host/pathogen cross-talk detection, drug target identification and systems drug design Presents flowcharts to represent the development procedure of systematic immunology and infection in a very clear format Contains 100 color diagrams to help readers understand the related biological networks, their corresponding mechanisms, and significant network biomarkers for therapeutic drug design

Evolutionary Concepts in Immunology

Author : Robert Jack
Publisher : Springer
ISBN 13 : 3030186679
Total Pages : 145 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Evolutionary Concepts in Immunology by : Robert Jack

Download or read book Evolutionary Concepts in Immunology written by Robert Jack and published by Springer. This book was released on 2019-06-13 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhansky’s famous slogan, “Nothing in biology makes sense except in the light of evolution”, this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.

Systems Biology for Signaling Networks

Author : Sangdun Choi
Publisher : Springer Science & Business Media
ISBN 13 : 1441957979
Total Pages : 900 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Systems Biology for Signaling Networks by : Sangdun Choi

Download or read book Systems Biology for Signaling Networks written by Sangdun Choi and published by Springer Science & Business Media. This book was released on 2010-08-09 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.

Immunity-Based Systems

Author : Yoshiteru Ishida
Publisher : Springer Science & Business Media
ISBN 13 : 9783540008965
Total Pages : 196 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Immunity-Based Systems by : Yoshiteru Ishida

Download or read book Immunity-Based Systems written by Yoshiteru Ishida and published by Springer Science & Business Media. This book was released on 2004-04-05 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: After I came to know Jerne's network theory on the immune system, I became fascinated with the immune system as an information system. The main pro totypes for biological information systems have been the neural systems and the brain. However, the immune system is not only an interesting informa tion system but it may provide a design paradigm for artificial information systems. With such a consideration, I initiated a project titled "autonomous decentralized recognition mechanism of the immune network and its applica tion to distributed information processing" in 1990 under a Grant-in-Aid for Scientific Research on a Priority Area ("Autonomous Distributed Systems") supported by the Ministry of Education, Science, and Culture. During the project, I promoted the idea that the immune system could be a prototype of autonomous distributed systems. After the project, we organized an international workshop on immunity based systems in 1996 in conjunction with the International Conference on Multi-Agent Systems held in Kyoto, Japan. Recently, there have been several international conferences related to topics inspired by the immune system and an increasing number of research papers related to the topic. In writing this book, a decade after the project, I still believe that the immune system can be a prototype, a compact but sophisticated system that nature has shown us for building artificial information systems in this network age of the twenty-first century.

Systems and Synthetic Immunology

Author : Shailza Singh
Publisher : Springer
ISBN 13 : 9789811533525
Total Pages : 0 pages
Book Rating : 4.5/5 (335 download)

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Book Synopsis Systems and Synthetic Immunology by : Shailza Singh

Download or read book Systems and Synthetic Immunology written by Shailza Singh and published by Springer. This book was released on 2021-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Systems Biology

Author : Edda Klipp
Publisher : John Wiley & Sons
ISBN 13 : 3527675663
Total Pages : 504 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Systems Biology by : Edda Klipp

Download or read book Systems Biology written by Edda Klipp and published by John Wiley & Sons. This book was released on 2016-03-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced textbook is tailored for an introductory course in Systems Biology and is well-suited for biologists as well as engineers and computer scientists. It comes with student-friendly reading lists and a companion website featuring a short exam prep version of the book and educational modeling programs. The text is written in an easily accessible style and includes numerous worked examples and study questions in each chapter. For this edition, a section on medical systems biology has been included.

Systems Immunology

Author : Jayajit Das
Publisher : CRC Press
ISBN 13 : 1351646141
Total Pages : 405 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Systems Immunology by : Jayajit Das

Download or read book Systems Immunology written by Jayajit Das and published by CRC Press. This book was released on 2018-09-03 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." –Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.

Handbook of Systems Biology

Author : Marian Walhout
Publisher : Academic Press
ISBN 13 : 012385945X
Total Pages : 552 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Handbook of Systems Biology by : Marian Walhout

Download or read book Handbook of Systems Biology written by Marian Walhout and published by Academic Press. This book was released on 2012-12-31 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines Includes the latest research developments in human and animal models to assist with translational research Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers

Acoustic Systems in Biology

Author : Neville H. Fletcher
Publisher : Oxford University Press
ISBN 13 : 0195069404
Total Pages : 348 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis Acoustic Systems in Biology by : Neville H. Fletcher

Download or read book Acoustic Systems in Biology written by Neville H. Fletcher and published by Oxford University Press. This book was released on 1992-07-23 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide for researchers and advanced graduate students in biology and biophysics who need a quantitative understanding of acoustical systems such as hearing, sound production, and vibration detection in animals at the physiological level. It begins with an introduction to physical acoustics, covering the fundamental concepts and showing how they can be applied quantitatively to understand auditory and sound-producing systems in animals. Only after the relatively simple mechanical part of the system is explained does the author focus his attention on the underlying physiological processes. The book is written on three levels. For those wanting a brief survey of the field, each chapter begins with a nonmathematical synopsis which summarizes the content and refers to the figures, all of which are designed to be understood apart from the main text. At the next level, the reader can follow the main text, but need not give close attention to anything but the general concepts and techniques involved. At the third level, the reader should follow the mathematical arguments in detail and attempt the discussion of questions at the end of each chapter. The author has provided detailed solutions which serve to expand the discussions of particular cases.

Systems Biology: A Very Short Introduction

Author : Eberhard O. Voit
Publisher : Oxford University Press
ISBN 13 : 0192563459
Total Pages : 161 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Systems Biology: A Very Short Introduction by : Eberhard O. Voit

Download or read book Systems Biology: A Very Short Introduction written by Eberhard O. Voit and published by Oxford University Press. This book was released on 2020-03-26 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology came about as growing numbers of engineers and scientists from other fields created algorithms which supported the analysis of biological data in incredible quantities. Whereas biologists of the past had been forced to study one item or aspect at a time, due to technical and biological limitations, it suddenly became possible to study biological phenomena within their natural contexts. This interdisciplinary field offers a holistic approach to interpreting these processes, and has been responsible for some of the most important developments in the science of human health and environmental sustainability. This Very Short Introduction outlines the exciting processes and possibilities in the new field of systems biology. Eberhard O. Voit describes how it enabled us to learn how intricately the expression of every gene is controlled, how signaling systems keep organisms running smoothly, and how complicated even the simplest cells are. He explores what this field is about, why it is needed, and how it will affect our understanding of life, particularly in the areas of personalized medicine, drug development, food and energy production, and sustainable stewardship of our environments. Throughout he considers how new tools are being provided from the fields of mathematics, computer science, engineering, physics, and chemistry to grasp the complexity of the countless interacting processes in cells which would overwhelm the cognitive and analytical capabilities of the human mind. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Theoretical and Applied Aspects of Systems Biology

Author : Fabricio Alves Barbosa da Silva
Publisher : Springer
ISBN 13 : 3319749749
Total Pages : 259 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Theoretical and Applied Aspects of Systems Biology by : Fabricio Alves Barbosa da Silva

Download or read book Theoretical and Applied Aspects of Systems Biology written by Fabricio Alves Barbosa da Silva and published by Springer. This book was released on 2018-06-21 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases. This book presents several chapters written by renowned experts in the field. Some topics discussed in depth in this book include: computational modeling of multiresistant bacteria, systems biology of cancer, systems immunology, networks in systems biology.

How the Immune System Works

Author : Lauren M. Sompayrac
Publisher : John Wiley & Sons
ISBN 13 : 1118997816
Total Pages : 160 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis How the Immune System Works by : Lauren M. Sompayrac

Download or read book How the Immune System Works written by Lauren M. Sompayrac and published by John Wiley & Sons. This book was released on 2015-09-16 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the Immune System Works has helped thousands of students understand what’s in their big, thick, immunology textbooks. In his book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject. In fifteen easy-to-read chapters, featuring the humorous style and engaging analogies developed by Dr. Sompayrac, How the Immune System Works explains how the immune system players work together to protect us from disease – and, most importantly, why they do it this way. Rigorously updated for this fifth edition, How the Immune System Works includes the latest information on subjects such as vaccines, the immunology of AIDS, and cancer. A highlight of this edition is a new chapter on the intestinal immune system – currently one of the hottest topics in immunology. Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject. But don’t take our word for it! Read what students have been saying about this classic book: "What an exceptional book! It's clear you are in the hands of an expert." "Possibly the Best Small Text of All Time!" "This is a FUN book, and Lauren Sompayrac does a fantastic job of explaining the immune system using words that normal people can understand." "Hands down the best immunology book I have read... a very enjoyable read." "This is simply one of the best medical textbooks that I have ever read. Clear diagrams coupled with highly readable text make this whole subject easily understandable and engaging." Now with a brand new website at www.wiley.com/go/sompayrac featuring Powerpoint files of the images from the book

Simulation Algorithms for Computational Systems Biology

Author : Luca Marchetti
Publisher : Springer
ISBN 13 : 3319631136
Total Pages : 238 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Simulation Algorithms for Computational Systems Biology by : Luca Marchetti

Download or read book Simulation Algorithms for Computational Systems Biology written by Luca Marchetti and published by Springer. This book was released on 2017-09-27 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies. This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.