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Systems Analysis Using Simulation And Markov Models
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Book Synopsis Secondary Analysis of Electronic Health Records by : MIT Critical Data
Download or read book Secondary Analysis of Electronic Health Records written by MIT Critical Data and published by Springer. This book was released on 2016-09-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.
Book Synopsis Input Modeling with Phase-Type Distributions and Markov Models by : Peter Buchholz
Download or read book Input Modeling with Phase-Type Distributions and Markov Models written by Peter Buchholz and published by Springer. This book was released on 2014-05-20 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing a summary of several recent results on Markov-based input modeling in a coherent notation, this book introduces and compares algorithms for parameter fitting and gives an overview of available software tools in the area. Due to progress made in recent years with respect to new algorithms to generate PH distributions and Markovian arrival processes from measured data, the models outlined are useful alternatives to other distributions or stochastic processes used for input modeling. Graduate students and researchers in applied probability, operations research and computer science along with practitioners using simulation or analytical models for performance analysis and capacity planning will find the unified notation and up-to-date results presented useful. Input modeling is the key step in model based system analysis to adequately describe the load of a system using stochastic models. The goal of input modeling is to find a stochastic model to describe a sequence of measurements from a real system to model for example the inter-arrival times of packets in a computer network or failure times of components in a manufacturing plant. Typical application areas are performance and dependability analysis of computer systems, communication networks, logistics or manufacturing systems but also the analysis of biological or chemical reaction networks and similar problems. Often the measured values have a high variability and are correlated. It’s been known for a long time that Markov based models like phase type distributions or Markovian arrival processes are very general and allow one to capture even complex behaviors. However, the parameterization of these models results often in a complex and non-linear optimization problem. Only recently, several new results about the modeling capabilities of Markov based models and algorithms to fit the parameters of those models have been published.
Book Synopsis An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation by : Gregory R. Bowman
Download or read book An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation written by Gregory R. Bowman and published by Springer Science & Business Media. This book was released on 2013-12-02 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book volume is to explain the importance of Markov state models to molecular simulation, how they work, and how they can be applied to a range of problems. The Markov state model (MSM) approach aims to address two key challenges of molecular simulation: 1) How to reach long timescales using short simulations of detailed molecular models. 2) How to systematically gain insight from the resulting sea of data. MSMs do this by providing a compact representation of the vast conformational space available to biomolecules by decomposing it into states sets of rapidly interconverting conformations and the rates of transitioning between states. This kinetic definition allows one to easily vary the temporal and spatial resolution of an MSM from high-resolution models capable of quantitative agreement with (or prediction of) experiment to low-resolution models that facilitate understanding. Additionally, MSMs facilitate the calculation of quantities that are difficult to obtain from more direct MD analyses, such as the ensemble of transition pathways. This book introduces the mathematical foundations of Markov models, how they can be used to analyze simulations and drive efficient simulations, and some of the insights these models have yielded in a variety of applications of molecular simulation.
Book Synopsis Guide to Modeling and Simulation of Systems of Systems by : Bernard Zeigler
Download or read book Guide to Modeling and Simulation of Systems of Systems written by Bernard Zeigler and published by Springer Science & Business Media. This book was released on 2012-10-22 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: This user’s reference is a companion to the separate book also titled “Guide to Modelling and Simulation of Systems of Systems.” The principal book explicates integrated development environments to support virtual building and testing of systems of systems, covering in some depth the MS4 Modelling EnvironmentTM. This user’s reference provides a quick reference and exposition of the various concepts and functional features covered in that book. The topics in the user’s reference are grouped in alignment with the workflow displayed on the MS4 Modeling EnvironmentTM launch page, under the headings Atomic Models, System Entity Structure, Pruning SES, and Miscellaneous. For each feature, the reference discusses why we use it, when we should use it, and how to use it. Further comments and links to related features are also included.
Book Synopsis Markov Chain Monte Carlo Simulations and Their Statistical Analysis by : Bernd A. Berg
Download or read book Markov Chain Monte Carlo Simulations and Their Statistical Analysis written by Bernd A. Berg and published by World Scientific. This book was released on 2004 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book teaches modern Markov chain Monte Carlo (MC) simulation techniques step by step. The material should be accessible to advanced undergraduate students and is suitable for a course. It ranges from elementary statistics concepts (the theory behind MC simulations), through conventional Metropolis and heat bath algorithms, autocorrelations and the analysis of the performance of MC algorithms, to advanced topics including the multicanonical approach, cluster algorithms and parallel computing. Therefore, it is also of interest to researchers in the field. The book relates the theory directly to Web-based computer code. This allows readers to get quickly started with their own simulations and to verify many numerical examples easily. The present code is in Fortran 77, for which compilers are freely available. The principles taught are important for users of other programming languages, like C or C++.
Book Synopsis Operations Research by : Michael W. Carter
Download or read book Operations Research written by Michael W. Carter and published by CRC Press. This book was released on 2017-12-19 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Students with diverse backgrounds will face a multitude of decisions in a variety of engineering, scientific, industrial, and financial settings. They will need to know how to identify problems that the methods of operations research (OR) can solve, how to structure the problems into standard mathematical models, and finally how to apply or develop computational tools to solve the problems. Perfect for any one-semester course in OR, Operations Research: A Practical Introduction answers all of these needs. In addition to providing a practical introduction and guide to using OR techniques, it includes a timely examination of innovative methods and practical issues related to the development and use of computer implementations. It provides a sound introduction to the mathematical models relevant to OR and illustrates the effective use of OR techniques with examples drawn from industrial, computing, engineering, and business applications. Many students will take only one course in the techniques of Operations Research. Operations Research: A Practical Introduction offers them the greatest benefit from that course through a broad survey of the techniques and tools available for quantitative decision making. It will also encourage other students to pursue more advanced studies and provides you a concise, well-structured, vehicle for delivering the best possible overview of the discipline.
Book Synopsis Reliability and Maintenance of Complex Systems by : Süleyman Özekici
Download or read book Reliability and Maintenance of Complex Systems written by Süleyman Özekici and published by Springer Science & Business Media. This book was released on 1996-06-18 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex high-technology devices are in growing use in industry, service sectors, and everyday life. Their reliability and maintenance is of utmost importance in view of their cost and critical functions. This book focuses on this theme and is intended to serve as a graduate-level textbook and reference book for scientists and academics in the field. The chapters are grouped into five complementary parts that cover the most important aspects of reliability and maintenance: stochastic models of reliability and maintenance, decision models involving optimal replacement and repair, stochastic methods in software engineering, computational methods and simulation, and maintenance management systems. This wide range of topics provides the reader with a complete picture in a self-contained volume.
Book Synopsis Simulation-Based Engineering of Complex Systems by : John R. Clymer
Download or read book Simulation-Based Engineering of Complex Systems written by John R. Clymer and published by John Wiley & Sons. This book was released on 2009-03-16 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hands-on approach to understanding, designing, analyzing, and evaluating complex systems During the last few years, Simulation-Based Systems Engineering (SBSE) has become an essential tool for the design and evaluation of complex systems. This is the first book to cover the basic principles of complex systems through the use of hands-on experimentation using an icon-based simulation tool. Utilizing the accompanying software tool ExtendSim, which works with the OpEMCSS library, readers are invited to engage in simulation-based experiments that demonstrate the principles of complex systems with an emphasis on design, analysis, and evaluation. A number of real-world examples are included to demonstrate how to model complex systems across a range of engineering, business, societal, economic, and scientific disciplines. Beginning with an introduction to SBSE, the book covers: Simulation concepts and building blocks Systems design and model development Markov model development Reliability processes Queuing theory in SBSE Rule-based learning and adaptation Agent motion and spatial interactions Multi-agent system of systems Assuming only a very basic background in problem-solving ability, this book is ideal as a textbook for students (a homework solution manual is also available) and as a reference book for practitioners in industry.
Book Synopsis Markov Processes for Stochastic Modeling by : Oliver Ibe
Download or read book Markov Processes for Stochastic Modeling written by Oliver Ibe and published by Newnes. This book was released on 2013-05-22 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Markov processes are processes that have limited memory. In particular, their dependence on the past is only through the previous state. They are used to model the behavior of many systems including communications systems, transportation networks, image segmentation and analysis, biological systems and DNA sequence analysis, random atomic motion and diffusion in physics, social mobility, population studies, epidemiology, animal and insect migration, queueing systems, resource management, dams, financial engineering, actuarial science, and decision systems. Covering a wide range of areas of application of Markov processes, this second edition is revised to highlight the most important aspects as well as the most recent trends and applications of Markov processes. The author spent over 16 years in the industry before returning to academia, and he has applied many of the principles covered in this book in multiple research projects. Therefore, this is an applications-oriented book that also includes enough theory to provide a solid ground in the subject for the reader. - Presents both the theory and applications of the different aspects of Markov processes - Includes numerous solved examples as well as detailed diagrams that make it easier to understand the principle being presented - Discusses different applications of hidden Markov models, such as DNA sequence analysis and speech analysis.
Book Synopsis Operations Research by : Michael Carter
Download or read book Operations Research written by Michael Carter and published by CRC Press. This book was released on 2018-08-06 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Operations Research: A Practical Introduction is just that: a hands-on approach to the field of operations research (OR) and a useful guide for using OR techniques in scientific decision making, design, analysis and management. The text accomplishes two goals. First, it provides readers with an introduction to standard mathematical models and algorithms. Second, it is a thorough examination of practical issues relevant to the development and use of computational methods for problem solving. Highlights: All chapters contain up-to-date topics and summaries A succinct presentation to fit a one-term course Each chapter has references, readings, and list of key terms Includes illustrative and current applications New exercises are added throughout the text Software tools have been updated with the newest and most popular software Many students of various disciplines such as mathematics, economics, industrial engineering and computer science often take one course in operations research. This book is written to provide a succinct and efficient introduction to the subject for these students, while offering a sound and fundamental preparation for more advanced courses in linear and nonlinear optimization, and many stochastic models and analyses. It provides relevant analytical tools for this varied audience and will also serve professionals, corporate managers, and technical consultants.
Book Synopsis Modeling and Simulation of Computer Networks and Systems by : Faouzi Zarai
Download or read book Modeling and Simulation of Computer Networks and Systems written by Faouzi Zarai and published by Morgan Kaufmann. This book was released on 2015-04-21 with total page 965 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling and Simulation of Computer Networks and Systems: Methodologies and Applications introduces you to a broad array of modeling and simulation issues related to computer networks and systems. It focuses on the theories, tools, applications and uses of modeling and simulation in order to effectively optimize networks. It describes methodologies for modeling and simulation of new generations of wireless and mobiles networks and cloud and grid computing systems. Drawing upon years of practical experience and using numerous examples and illustrative applications recognized experts in both academia and industry, discuss: - Important and emerging topics in computer networks and systems including but not limited to; modeling, simulation, analysis and security of wireless and mobiles networks especially as they relate to next generation wireless networks - Methodologies, strategies and tools, and strategies needed to build computer networks and systems modeling and simulation from the bottom up - Different network performance metrics including, mobility, congestion, quality of service, security and more... Modeling and Simulation of Computer Networks and Systems is a must have resource for network architects, engineers and researchers who want to gain insight into optimizing network performance through the use of modeling and simulation. - Discusses important and emerging topics in computer networks and Systems including but not limited to; modeling, simulation, analysis and security of wireless and mobiles networks especially as they relate to next generation wireless networks - Provides the necessary methodologies, strategies and tools needed to build computer networks and systems modeling and simulation from the bottom up - Includes comprehensive review and evaluation of simulation tools and methodologies and different network performance metrics including mobility, congestion, quality of service, security and more
Download or read book Simulation written by Sheldon M. Ross and published by Academic Press. This book was released on 2022-06-14 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simulation, Sixth Edition continues to introduce aspiring and practicing actuaries, engineers, computer scientists and others to the practical aspects of constructing computerized simulation studies to analyze and interpret real phenomena. Readers will learn to apply the results of these analyses to problems in a wide variety of fields to obtain effective, accurate solutions and make predictions. By explaining how a computer can be used to generate random numbers and how to use these random numbers to generate the behavior of a stochastic model over time, this book presents the statistics needed to analyze simulated data and validate simulation models. - Includes updated content throughout - Offers a wealth of practice exercises as well as applied use of free software package R - Features the author's well-known, award-winning and accessible approach to complex information
Book Synopsis Modeling for Reliability Analysis by : Jan Pukite
Download or read book Modeling for Reliability Analysis written by Jan Pukite and published by John Wiley & Sons. This book was released on 1998-06-22 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Markov modeling has long been accepted as a fundamental and powerful technique for the fault tolerance analysis of mission-critical applications. However, the elaborate computations required have often made Markov modeling too time-consuming to be of practical use on these complex systems. With this hands-on tool, designers can use the Markov modeling technique to analyze safety, reliability, maintainability, and cost-effectiveness factors in the full range of complex systems in use today. Featuring ground-breaking simulation software and a comprehensive reference manual, MARKOV MODELING FOR RELIABILITY ANALYSIS helps system designers surmount the mathematical computations that have previously prevented effective reliability analysis. The text and software compose a valuable self-study tool that is complete with detailed explanations, examples, and a library of Markov models that can be used for experiments and as derivations for new simulation models. The book details how these analyses are conducted, while providing hands-on instruction on how to develop reliability models for the full range of system configurations. Computer-Aided Rate Modeling and Simulation (CARMS) software is an integrated modeling tool that includes a diagram-based environment for model setup, a spreadsheet like interface for data entry, an expert system link for automatic model construction, and an interactive graphic interface for displaying simulation results."
Download or read book NBS Special Publication written by and published by . This book was released on 1968 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Queueing Networks and Markov Chains by : Gunter Bolch
Download or read book Queueing Networks and Markov Chains written by Gunter Bolch and published by John Wiley & Sons. This book was released on 2006-04-14 with total page 901 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critically acclaimed text for computer performance analysis--now in its second edition The Second Edition of this now-classic text provides a current and thorough treatment of queueing systems, queueing networks, continuous and discrete-time Markov chains, and simulation. Thoroughly updated with new content, as well as new problems and worked examples, the text offers readers both the theory and practical guidance needed to conduct performance and reliability evaluations of computer, communication, and manufacturing systems. Starting with basic probability theory, the text sets the foundation for the more complicated topics of queueing networks and Markov chains, using applications and examples to illustrate key points. Designed to engage the reader and build practical performance analysis skills, the text features a wealth of problems that mirror actual industry challenges. New features of the Second Edition include: * Chapter examining simulation methods and applications * Performance analysis applications for wireless, Internet, J2EE, and Kanban systems * Latest material on non-Markovian and fluid stochastic Petri nets, as well as solution techniques for Markov regenerative processes * Updated discussions of new and popular performance analysis tools, including ns-2 and OPNET * New and current real-world examples, including DiffServ routers in the Internet and cellular mobile networks With the rapidly growing complexity of computer and communication systems, the need for this text, which expertly mixes theory and practice, is tremendous. Graduate and advanced undergraduate students in computer science will find the extensive use of examples and problems to be vital in mastering both the basics and the fine points of the field, while industry professionals will find the text essential for developing systems that comply with industry standards and regulations.
Book Synopsis Simulation Modeling and Analysis with ARENA by : Tayfur Altiok
Download or read book Simulation Modeling and Analysis with ARENA written by Tayfur Altiok and published by Elsevier. This book was released on 2010-07-26 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simulation Modeling and Analysis with Arena is a highly readable textbook which treats the essentials of the Monte Carlo discrete-event simulation methodology, and does so in the context of a popular Arena simulation environment. It treats simulation modeling as an in-vitro laboratory that facilitates the understanding of complex systems and experimentation with what-if scenarios in order to estimate their performance metrics. The book contains chapters on the simulation modeling methodology and the underpinnings of discrete-event systems, as well as the relevant underlying probability, statistics, stochastic processes, input analysis, model validation and output analysis. All simulation-related concepts are illustrated in numerous Arena examples, encompassing production lines, manufacturing and inventory systems, transportation systems, and computer information systems in networked settings. - Introduces the concept of discrete event Monte Carlo simulation, the most commonly used methodology for modeling and analysis of complex systems - Covers essential workings of the popular animated simulation language, ARENA, including set-up, design parameters, input data, and output analysis, along with a wide variety of sample model applications from production lines to transportation systems - Reviews elements of statistics, probability, and stochastic processes relevant to simulation modeling
Book Synopsis Transportation Systems Analysis and Assessment by : Stefano De Luca
Download or read book Transportation Systems Analysis and Assessment written by Stefano De Luca and published by BoD – Books on Demand. This book was released on 2020-01-22 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The transportation system is the backbone of any social and economic system, and is also a very complex system in which users, transport means, technologies, services, and infrastructures have to cooperate with each other to achieve common and unique goals.The aim of this book is to present a general overview on some of the main challenges that transportation planners and decision makers are faced with. The book addresses different topics that range from user's behavior to travel demand simulation, from supply chain to the railway infrastructure capacity, from traffic safety issues to Life Cycle Assessment, and to strategies to make the transportation system more sustainable.
