Synthetic Biology Handbook

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Author :
Publisher : CRC Press
ISBN 13 : 1466568488
Total Pages : 328 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Synthetic Biology Handbook by : Darren N. Nesbeth

Download or read book Synthetic Biology Handbook written by Darren N. Nesbeth and published by CRC Press. This book was released on 2016-04-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook:Explores the standardisation of classic molecular bioscience approaches

Synthetic Biology

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Publisher : Academic Press
ISBN 13 : 0123978203
Total Pages : 352 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Synthetic Biology by : Huimin Zhao

Download or read book Synthetic Biology written by Huimin Zhao and published by Academic Press. This book was released on 2013-03-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development

Regenesis

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Publisher : Basic Books
ISBN 13 : 0465038654
Total Pages : 305 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Regenesis by : George M Church

Download or read book Regenesis written by George M Church and published by Basic Books. This book was released on 2014-04-08 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Synthetic Biology - a Primer (revised Edition)

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Publisher : World Scientific
ISBN 13 : 1783268808
Total Pages : 194 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Synthetic Biology - a Primer (revised Edition) by : Paul S. FREEMONT

Download or read book Synthetic Biology - a Primer (revised Edition) written by Paul S. FREEMONT and published by World Scientific. This book was released on 2015-08-24 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology -- A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems.Examples of cutting-edge applications designed using synthetic biology principles are presented, including: The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research.Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology.

Synthetic Biology

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Publisher : Springer
ISBN 13 : 9401793824
Total Pages : 86 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Synthetic Biology by : Manuel Porcar

Download or read book Synthetic Biology written by Manuel Porcar and published by Springer. This book was released on 2014-09-09 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the ‘top-down’ and ‘bottom-up’ approaches towards the construction of an artificial cell and the development of the “iGEM” competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.

Synthetic Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 9048126789
Total Pages : 190 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Synthetic Biology by : Markus Schmidt

Download or read book Synthetic Biology written by Markus Schmidt and published by Springer Science & Business Media. This book was released on 2009-09-16 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology is becoming one of the most dynamic new fields of biology, with the potential to revolutionize the way we do biotechnology today. By applying the toolbox of engineering disciplines to biology, a whole set of potential applications become possible ranging very widely across scientific and engineering disciplines. Some of the potential benefits of synthetic biology, such as the development of low-cost drugs or the production of chemicals and energy by engineered bacteria are enormous. There are, however, also potential and perceived risks due to deliberate or accidental damage. Also, ethical issues of synthetic biology just start being explored, with hardly any ethicists specifically focusing on the area of synthetic biology. This book will be the first of its kind focusing particularly on the safety, security and ethical concerns and other relevant societal aspects of this new emerging field. The foreseen impact of this book will be to stimulate a debate on these societal issues at an early stage. Past experiences, especially in the field of GM-crops and stem cells, have shown the importance of an early societal debate. The community and informed stakeholders recognize this need, but up to now discussions are fragmentary. This book will be the first comprehensive overview on relevant societal issues of synthetic biology, setting the scene for further important discussions within the scientific community and with civil society.

Advances in Synthetic Biology

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Author :
Publisher : Springer Nature
ISBN 13 : 9811500819
Total Pages : 349 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Advances in Synthetic Biology by : Vijai Singh

Download or read book Advances in Synthetic Biology written by Vijai Singh and published by Springer Nature. This book was released on 2020-04-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Systems and Synthetic Biology

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Author :
Publisher : Springer
ISBN 13 : 9401795142
Total Pages : 383 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Systems and Synthetic Biology by : Vikram Singh

Download or read book Systems and Synthetic Biology written by Vikram Singh and published by Springer. This book was released on 2014-12-15 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.

Cell-Free Synthetic Biology

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889740803
Total Pages : 205 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cell-Free Synthetic Biology by : Jian Li

Download or read book Cell-Free Synthetic Biology written by Jian Li and published by Frontiers Media SA. This book was released on 2022-01-13 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:

BioBuilder

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Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1491907533
Total Pages : 293 pages
Book Rating : 4.4/5 (919 download)

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Book Synopsis BioBuilder by : Natalie Kuldell PhD.

Download or read book BioBuilder written by Natalie Kuldell PhD. and published by "O'Reilly Media, Inc.". This book was released on 2015-06-22 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene

Synthetic Biology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527688099
Total Pages : 532 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Synthetic Biology by : Christina Smolke

Download or read book Synthetic Biology written by Christina Smolke and published by John Wiley & Sons. This book was released on 2018-02-28 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.

Handbook of Research on Systems Biology Applications in Medicine

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Publisher : IGI Global
ISBN 13 : 1605660779
Total Pages : 982 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Handbook of Research on Systems Biology Applications in Medicine by : Daskalaki, Andriani

Download or read book Handbook of Research on Systems Biology Applications in Medicine written by Daskalaki, Andriani and published by IGI Global. This book was released on 2008-11-30 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.

Synthetic Biology

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Author :
Publisher : Perspectives Cshl
ISBN 13 : 9781621821182
Total Pages : 0 pages
Book Rating : 4.8/5 (211 download)

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Book Synopsis Synthetic Biology by : Daniel G. Gibson

Download or read book Synthetic Biology written by Daniel G. Gibson and published by Perspectives Cshl. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology involves the rational design and construction of biological components and systemsfrom genetic elements and metabolic pathways to entirely new organisms. Progress in this field has been rapid, and it promises to significantly expand our capabilities in biotechnology, medicine, and agriculture. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the tools and techniques employed by synthetic biologists, how these may be used to develop new drugs, diagnostic approaches, food sources, and clean energy, and what the field of synthetic biology has taught us about natural living systems. The contributors discuss advances in DNA synthesis and assembly, genome editing (e.g., CRISPR/Cas9), and artificial genetic systems. Progress in designing complex genetic switches and circuits, expanding the genetic code, modifying cellular organization, producing proteins using cell-free systems, and developing biodesign automation tools is also covered. The authors also explore ways to produce new organisms and products that have particular attributesfor example, microbial "molecular factories," synthetic organs and tissues, and plants with novel traits. This volume is an essential resource for molecular, cell, and systems biologists who seek to engineer living systems for human benefit.

Synthetic Biology: A Lab Manual

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Publisher : World Scientific
ISBN 13 : 9814579564
Total Pages : 204 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Synthetic Biology: A Lab Manual by : Forster Anthony C

Download or read book Synthetic Biology: A Lab Manual written by Forster Anthony C and published by World Scientific. This book was released on 2014-04-16 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology: A Lab Manual is the first manual for laboratory work in the new and rapidly expanding field of synthetic biology. Aimed at non-specialists, it details protocols central to synthetic biology in both education and research. In addition, it provides all the information that teachers and students from high schools and tertiary institutions need for a colorful lab course in bacterial synthetic biology using chromoproteins and designer antisense RNAs. As a bonus, practical material is provided for students of the annual international Genetically Engineered Machine (iGEM) competition. The manual is based upon a highly successful course at Sweden's Uppsala University and is coauthored by one of the pioneers of synthetic biology and two bioengineering postgraduate students.An inspiring foreword is written by another pioneer in the field, Harvard's George Church: “Synthetic biology is to early recombinant DNA as a genome is to a gene. Is there anything that SynBio will not impact? There was no doubt that the field of SynBio needed ‘A Lab Manual’ such as the one that you now hold in your hands.”

Handbook on Biological Networks

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Author :
Publisher : World Scientific
ISBN 13 : 9812838791
Total Pages : 465 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Handbook on Biological Networks by : Stefano Boccaletti

Download or read book Handbook on Biological Networks written by Stefano Boccaletti and published by World Scientific. This book was released on 2010 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.

New Frontiers and Applications of Synthetic Biology

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Author :
Publisher : Academic Press
ISBN 13 : 0323859860
Total Pages : 487 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis New Frontiers and Applications of Synthetic Biology by : Vijai Singh

Download or read book New Frontiers and Applications of Synthetic Biology written by Vijai Singh and published by Academic Press. This book was released on 2022-01-12 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. Offers basic understanding and knowledge in several aspects of synthetic biology Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Synthetic Biology

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Author :
Publisher : Oxford University Press
ISBN 13 : 019252528X
Total Pages : 159 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Synthetic Biology by : Jamie A. Davies

Download or read book Synthetic Biology written by Jamie A. Davies and published by Oxford University Press. This book was released on 2018-06-14 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic biology is one of the 21st century's fastest growing fields of research, as important for technology as for basic science. Building on traditional genetic engineering, which was restricted to changing one or two genes, synthetic biology uses multi-gene modules and pathways to make very significant changes to what cells can do. Synthetic biologists aim to have an impact in fields as diverse as drug manufacture, biofuel production, tackling pollution, and medical diagnostics. Further ahead, synthetic biology may even make possible the long-standing goal of creating new life from non-living starting materials. This Very Short Introduction provides a concise explanation of what synthetic biology is, and how it is beginning to affect many fields of technology. Jamie Davies also discusses the considerable controversies surrounding synthetic biology, from questions over the assumption that engineering concepts can be applied to living systems easily, to scepticism over the claims for commercial promise, fears that the dangers of engineering life are worse than its benefits, and concerns over whether humans should be designing living systems at all. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.