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Author : Kelvin K. C. Sham
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.:/5 (328 download)
Download or read book Synthesis of Benzofurans Via Palladium-catalyzed Annulation of Internal Alkynes written by Kelvin K. C. Sham and published by . This book was released on 1992 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark Joseph Doty
Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.:/5 (338 download)
Download or read book Palladium-catalyzed Annulation of Internal Alkynes written by Mark Joseph Doty and published by . This book was released on 1995 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Navjeet Kaur
Publisher : CRC Press
ISBN 13 : 1351242601
Total Pages : 432 pages
Book Rating : 4.3/5 (512 download)
Download or read book Palladium Assisted Synthesis of Heterocycles written by Navjeet Kaur and published by CRC Press. This book was released on 2019-05-01 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of the recent applications of palladium catalysts in organic synthesis. The book demonstrates that it is a highly dynamic research field. This methodology has emerged as a powerful tool for the efficient and chemoselective synthesis of heterocyclic molecules. In the past few years, several strategies have been pointed out to pursue more efficient, sustainable, and environment friendly chemical processes. Among those strategies, catalysis and the design of new processes that avoid the use of toxic reagents have been the focus of intense research.
Author : Gianfranco Favi
Publisher : MDPI
ISBN 13 : 3036503404
Total Pages : 372 pages
Book Rating : 4.0/5 (365 download)
Download or read book Modern Strategies for Heterocycle Synthesis written by Gianfranco Favi and published by MDPI. This book was released on 2021-03-17 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.
Author : Vasyl Andrushko
Publisher : John Wiley & Sons
ISBN 13 : 1118628330
Total Pages : 1836 pages
Book Rating : 4.1/5 (186 download)
Download or read book Stereoselective Synthesis of Drugs and Natural Products written by Vasyl Andrushko and published by John Wiley & Sons. This book was released on 2013-08-16 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Author : Xiao-Feng Wu
Publisher : John Wiley & Sons
ISBN 13 : 3527338888
Total Pages : 596 pages
Book Rating : 4.5/5 (273 download)
Download or read book Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation written by Xiao-Feng Wu and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.
Author : Wade H. Shafer
Publisher : Springer Science & Business Media
ISBN 13 : 1461303931
Total Pages : 427 pages
Book Rating : 4.4/5 (613 download)
Download or read book Masters Theses in the Pure and Applied Sciences written by Wade H. Shafer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Masters Theses in the Pure and Applied Sciences was first conceived, published, and disseminated by the Center for Information and Numerical Data Analysis and Synthesis (CINDAS)* at Purdue University in 1957, starting its coverage of theses with the academic year 1955. Beginning with Volume 13, the printing and dis semination phases of the activity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all concerned if the printing and distribution of the volumes were handled by an international publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Corporation of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 39 (thesis year 1994) a total of 13,953 thesis titles from 21 Canadian and 159 United States universities. We are sure that this broader base for these titles reported will greatly enhance the value of this impor tant annual reference work. While Volume 39 reports theses submitted in 1994, on occasion, certain uni versities do report theses submitted in previous years but not reported at the time.
Author : Charles K. Zercher
Publisher : John Wiley & Sons
ISBN 13 : 1118117824
Total Pages : 1606 pages
Book Rating : 4.1/5 (181 download)
Download or read book Organic Syntheses, Collective Volume 12 written by Charles K. Zercher and published by John Wiley & Sons. This book was released on 2015-10-19 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the tradition of providing significant and interesting procedures, Organic Syntheses, Collective Volume XII is a compilation of revised editions of Annual Volumes 85 through 89. The contents of this volume are organized by primarily by reaction type, with the precise classification made according to the bias of the editor, who attempted to ascertain the primary purpose or utility of the procedure.
Download or read book Palladium‐Catalyzed Regioselective Aromatic Extension of Internal Alkynes Through a Norbornene‐Controlled Reaction Sequence written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tamás Patonay
Publisher : Springer
ISBN 13 : 3319326104
Total Pages : 371 pages
Book Rating : 4.3/5 (193 download)
Download or read book Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions written by Tamás Patonay and published by Springer. This book was released on 2016-06-15 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
Author : Navjeet Kaur
Publisher : Elsevier
ISBN 13 : 0443134243
Total Pages : 442 pages
Book Rating : 4.4/5 (431 download)
Download or read book Synthesis of 5-Membered Heterocycles written by Navjeet Kaur and published by Elsevier. This book was released on 2023-09-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units. Includes comprehensive descriptions of heterocycle synthesis Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide Helps readers quickly assess possible synthetic approaches
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1995 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xiao-Feng Wu
Publisher : Elsevier
ISBN 13 : 0128093706
Total Pages : 79 pages
Book Rating : 4.1/5 (28 download)
Download or read book Transition Metal-Catalyzed Benzofuran Synthesis written by Xiao-Feng Wu and published by Elsevier. This book was released on 2017-02-01 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series provides an overview of benzofuran, describing properties of these heterocycle compounds and the traditional synthetic procedures used for them. The book then explores catalyzed procedures for benzofuran synthesis in greater detail and depth than is currently available in published review articles. This volume is part of the short series authored by Xiao-Feng Wu that summarizes recent achievements on heterocycle synthesis with transition metals as catalysts, with each volume dedicated to one heterocycle compound. - Offers a brief, focused review of this active research in benzofuran synthesis via transition metal catalysis - Useful coverage of benzofuran properties and both intermolecular and intramolecular cyclization - Volume Four in Elsevier's short work series, Transition Metal-Catalyzed Heterocycles Synthesis - Provides greater detail and depth than is currently available in published review articles
Author : Navjeet Kaur
Publisher : CRC Press
ISBN 13 : 1000733416
Total Pages : 404 pages
Book Rating : 4.0/5 (7 download)
Download or read book Metals and Non-metals written by Navjeet Kaur and published by CRC Press. This book was released on 2020-01-28 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.
Author : Xiao-Feng Wu
Publisher : Royal Society of Chemistry
ISBN 13 : 1782621369
Total Pages : 315 pages
Book Rating : 4.7/5 (826 download)
Download or read book Heterocycles from Double-Functionalized Arenes written by Xiao-Feng Wu and published by Royal Society of Chemistry. This book was released on 2015 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to transition metal catalyzed coupling reactions of double-functionalized arenes in heterocycle synthesis.
Author : Valentine Nenajdenko
Publisher : Springer
ISBN 13 : 3319043463
Total Pages : 683 pages
Book Rating : 4.3/5 (19 download)
Download or read book Fluorine in Heterocyclic Chemistry Volume 1 written by Valentine Nenajdenko and published by Springer. This book was released on 2014-06-30 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.
Author : Xiaojun Han
Publisher :
ISBN 13 :
Total Pages : 644 pages
Book Rating : 4.:/5 (44 download)
Download or read book Palladium-catalyzed Synthesis of Heterocycles and Highly Functionalized Polycyclics written by Xiaojun Han and published by . This book was released on 1998 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Palladium catalyzes the regio- and stereoselective annulation of allenes by vinylic halides bearing tertiary alcohol and p-toluenesulfonamide groups to produce a variety of 5- and 6-membered ring heterocycles containing a 1,3-diene moiety. In addition, the palladium-catalyzed reaction of N-(2-iodo-2-alkenyl)--P-toluenesulfonamides with diphenylacetylene or 4,4-dimethyl-2-pentyne affords pyrolidine derivatives containing a 1,3-diene moiety, or unexpected 2-alkenyl substituted [Alpha, Beta-]unsaturated aldehydes. These synthetically useful intermediates are difficult to prepare or inaccessible by other existing methodology. A number of 3,4,6-tri- and 3,4,5,6-tetrasubstituted [Alpha]-pyrones have been prepared in good yields by the reaction of vinylic iodides or triflates bearing ester functionality with internal alkynes in the presence of a palladium catalyst. The methodology provides an especially simple, convenient, and regioselective route to [Alpha]-pyrones containing aryl, silyl, tert.-alkyl and other hindered groups.
