Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile

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Publisher : MDPI
ISBN 13 : 3039213156
Total Pages : 204 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile by : Maria Contel

Download or read book Unconventional Anticancer Metallodrugs and Strategies to Improve their Pharmacological Profile written by Maria Contel and published by MDPI. This book was released on 2019-10-01 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the past 40 years, metal-based drugs have been widely used for the treatment of cancer. Cisplatin and follow-up drugs carboplatin (ParaplatinTM) and oxaliplatin (EloxatinTM) have been the gold standard for metallodrugs in clinical settings as antineoplastic agents. While effective, these drugs (either alone or in combination therapy) have faced a number of clinical challenges resulting from their limited spectrum of activity, high toxicity leading to significant side effects, resistance, poor water solubility, low bioavailability and short circulating time. In the past 10 years, various unconventional non-platinum metal-based agents have emerged as a potential alternative for cancer treatment. These compounds are highly effective and selective in cancers resistant to cisplatin and other chemotherapeutic agents. Research in this area has recently exploded with a relevant number of patents and clinical trials, in addition to reports in scientific journals. Furthermore, in parallel to the synthesis of coordination and organometallic compounds comprising many different metals and unconventional platinum-based derivatives, researchers are focused on optimizing mechanistic and pharmacological features of promising drug candidates. This Special Issue aims to highlight the latest advances in anticancer metallodrugs with a focus on unconventional anticancer agents, as well as novel activation, targeting and delivery strategies aimed at improving their pharmacological profile.

Handbook on the Physics and Chemistry of Rare Earths

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Author :
Publisher : Elsevier
ISBN 13 : 0444634932
Total Pages : 398 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Handbook on the Physics and Chemistry of Rare Earths by :

Download or read book Handbook on the Physics and Chemistry of Rare Earths written by and published by Elsevier. This book was released on 2015-10-14 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on the Physics and Chemistry of Rare Earths is a continuing series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science, and physics. The handbook emphasizes rare earth elements [Sc, Y and the lanthanides (La through Lu)] but, when relevant, information also is included about the closely related actinide elements. The individual chapters are comprehensive, broad, up-to-date critical reviews written by highly experienced invited experts. The series, which was started in 1978 by Professor Karl A. Gschneidner, Jr., combines and integrates both the fundamentals and applications of these elements and now publishes two volumes a year. - Covers all aspects of rare earth science, including chemistry, life sciences, materials science, and physics. - Includes contributions from highly experienced, invited experts - Provides comprehensive, up-to-date critical reviews of developments in the field - Combines and integrates both the fundamentals and applications of rare earth elements

Emerging Sustainable Nanomaterials for Biomedical Applications

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Publisher : Springer Nature
ISBN 13 : 3031639618
Total Pages : 467 pages
Book Rating : 4.0/5 (316 download)

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Book Synopsis Emerging Sustainable Nanomaterials for Biomedical Applications by : Seema Garg

Download or read book Emerging Sustainable Nanomaterials for Biomedical Applications written by Seema Garg and published by Springer Nature. This book was released on with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanobiomaterials in Medical Imaging

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Publisher : William Andrew
ISBN 13 : 0323417388
Total Pages : 519 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanobiomaterials in Medical Imaging by : Alexandru Grumezescu

Download or read book Nanobiomaterials in Medical Imaging written by Alexandru Grumezescu and published by William Andrew. This book was released on 2016-04-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques. The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. - A valuable resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields - A detailed guide to recent scientific progress, along with the latest application methods - Presents innovative opportunities and ideas for developing or improving technologies in nanomedicine and medical imaging

Magnetic Resonance Imaging in Tissue Engineering

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Publisher : John Wiley & Sons
ISBN 13 : 1119193354
Total Pages : 444 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Magnetic Resonance Imaging in Tissue Engineering by : Mrignayani Kotecha

Download or read book Magnetic Resonance Imaging in Tissue Engineering written by Mrignayani Kotecha and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine

Hybrid Nanomaterials

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Publisher : CRC Press
ISBN 13 : 1498720943
Total Pages : 451 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Hybrid Nanomaterials by : Weibo Cai

Download or read book Hybrid Nanomaterials written by Weibo Cai and published by CRC Press. This book was released on 2017-05-25 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, an unprecedented expansion in the field of nanomedicine has resulted in the development of new nanomaterials for diagnosis and therapy of various diseases such as cancer. This book covers the design, synthesis and applications of various functionally-hybridized nanomaterials for biomedical applications. It includes strategies for design and synthesis of hybrid nanomaterials, surface engineering of various nanoparticle-based hybrid nanosystems for cancer imaging and therapy, toxicity aspects of nanomaterials and the challenges in translation research of hybrid nanomaterials.

Persistent Luminescence

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Author :
Publisher : Springer Nature
ISBN 13 : 9819749433
Total Pages : 403 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Persistent Luminescence by : Vijay Kumar

Download or read book Persistent Luminescence written by Vijay Kumar and published by Springer Nature. This book was released on with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemoselective and Bioorthogonal Ligation Reactions

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Publisher : John Wiley & Sons
ISBN 13 : 352768347X
Total Pages : 923 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Chemoselective and Bioorthogonal Ligation Reactions by : W. Russ Algar

Download or read book Chemoselective and Bioorthogonal Ligation Reactions written by W. Russ Algar and published by John Wiley & Sons. This book was released on 2017-03-17 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely, one-stop reference is the first on an emerging and interdisciplinary topic. Covering both established and recently developed ligation chemistries, the book is divided into two didactic parts: a section that focuses on the details of bioorthogonal and chemoselective ligation reactions at the level of fundamental organic chemistry, and a section that focuses on applications, particularly in the areas of chemical biology, biomaterials, and bioanalysis, highlighting the capabilities and benefits of the ligation reactions. With chapters authored by outstanding scientists who range from trailblazers in the field to young and emerging leaders, this book on a highly interdisciplinary topic will be of great interest for biochemists, biologists, materials scientists, pharmaceutical chemists, organic chemists, and many others.

Luminescence

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Publisher : BoD – Books on Demand
ISBN 13 : 9535127624
Total Pages : 390 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Luminescence by : Jagannathan Thirumalai

Download or read book Luminescence written by Jagannathan Thirumalai and published by BoD – Books on Demand. This book was released on 2016-11-10 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to give readers a broad review of topical worldwide advancements in theoretical and experimental facts, instrumentation and practical applications erudite by luminescent materials and their prospects in dealing with different types of luminescence like photoluminescence, electroluminescence, thermo-luminescence, triboluminescence, bioluminescence design and applications. The additional part of this book deals with the dynamics, rare-earth ions, photon down-/up-converting materials, luminescence dating, lifetime, bioluminescence microscopical perspectives and prospects towards the basic research or for more advanced applications. This book is divided into four main sections: luminescent materials and their associated phenomena; photo-physical properties and their emerging applications; thermoluminescence dating: from theory to applications, and bioluminescence perspectives and prospects. Individual chapters should serve the broad spectrum of common readers of diverse expertise, layman, students and researchers, who may in this book find easily elucidated fundamentals as well as progressive principles of specific subjects associated with these phenomena. This book was created by 14 contributions from experts in different fields of luminescence and technology from over 20 research institutes worldwide.

Transmission Electron Microscopy

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Publisher : Springer Science & Business Media
ISBN 13 : 1475725191
Total Pages : 708 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Transmission Electron Microscopy by : David B. Williams

Download or read book Transmission Electron Microscopy written by David B. Williams and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electron microscopy has revolutionized our understanding the extraordinary intellectual demands required of the mi of materials by completing the processing-structure-prop croscopist in order to do the job properly: crystallography, erties links down to atomistic levels. It now is even possible diffraction, image contrast, inelastic scattering events, and to tailor the microstructure (and meso structure ) of materials spectroscopy. Remember, these used to be fields in them to achieve specific sets of properties; the extraordinary abili selves. Today, one has to understand the fundamentals ties of modem transmission electron microscopy-TEM of all of these areas before one can hope to tackle signifi instruments to provide almost all of the structural, phase, cant problems in materials science. TEM is a technique of and crystallographic data allow us to accomplish this feat. characterizing materials down to the atomic limits. It must Therefore, it is obvious that any curriculum in modem mate be used with care and attention, in many cases involving rials education must include suitable courses in electron mi teams of experts from different venues. The fundamentals croscopy. It is also essential that suitable texts be available are, of course, based in physics, so aspiring materials sci for the preparation of the students and researchers who must entists would be well advised to have prior exposure to, for carry out electron microscopy properly and quantitatively.

Spectroscopy of Lanthanide Doped Oxide Materials

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Publisher : Woodhead Publishing
ISBN 13 : 0081029365
Total Pages : 454 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Spectroscopy of Lanthanide Doped Oxide Materials by : Sanjay J. Dhoble

Download or read book Spectroscopy of Lanthanide Doped Oxide Materials written by Sanjay J. Dhoble and published by Woodhead Publishing. This book was released on 2019-10-30 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectroscopy of Lanthanide Doped Oxide Materials provides a comprehensive overview on the most essential characterization techniques of these materials, along with their key applications. The book describes the application of optical spectroscopy of lanthanides doped inorganic phosphor hosts and gives information about their structure and morphology, binding energies, energy of transition and band gap. Also discussed are the properties and applications of rare earth doped inorganic materials and the barriers and potential solutions to enable the commercial realization of phosphors in important applications. The book reviews key information for those entering the field of phosphor research, along with the fundamental knowledge of the properties of transition series elements under UV/Visible/NIR light exposer. Low-cost materials methods to synthesize the materials and spectroscopic characterization methods are also detailed. - Reviews the barriers and potential solutions to enable commercial realization of inorganic phosphors - Discusses low-cost material methods to synthesize and characterize lanthanide doped oxide materials - Provides readers with a comprehensive overview on key properties for the most relevant applications, such as lighting and display, energy conversion and solar cell devices

Nanomaterials and Their Biomedical Applications

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Publisher : Springer Nature
ISBN 13 : 9813362529
Total Pages : 552 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Nanomaterials and Their Biomedical Applications by : Tuhin Subhra Santra

Download or read book Nanomaterials and Their Biomedical Applications written by Tuhin Subhra Santra and published by Springer Nature. This book was released on 2021-04-16 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.

Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials

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Publisher : John Wiley & Sons
ISBN 13 : 1118682815
Total Pages : 408 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials by : Ana de Bettencourt-Dias

Download or read book Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials written by Ana de Bettencourt-Dias and published by John Wiley & Sons. This book was released on 2014-09-08 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book presents the theoretical principles, current applications and latest research developments in the field of luminescent lanthanide complexes; a rapidly developing area of research which is attracting increasing interest amongst the scientific community. Luminescence of Lanthanide Ions in Coordination Compounds and Nanomaterials begins with an introduction to the basic theoretical and practical aspects of lanthanide ion luminescence, and the spectroscopic techniques used to evaluate the efficiency of luminescence. Subsequent chapters introduce a variety of different applications including: • Circularly polarized luminescence • Luminescence bioimaging with lanthanide complexes • Two-photon absorption of lanthanide complexes • Chemosensors • Upconversion luminescence • Excitation spectroscopy • Heterometallic complexes containing lanthanides Each chapter presents a detailed introduction to the application, followed by a description of experimental techniques specific to the area and an extensive review of recent literature. This book is a valuable introduction to the literature for scientists new to the field, as well as providing the more experienced researcher with a comprehensive resource covering the most relevant information in the field; a ‘one stop shop’ for all key references.

MRI

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Publisher : John Wiley & Sons
ISBN 13 : 1119013038
Total Pages : 246 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis MRI by : Brian M. Dale

Download or read book MRI written by Brian M. Dale and published by John Wiley & Sons. This book was released on 2015-08-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Upconverting Nanomaterials

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Publisher : CRC Press
ISBN 13 : 1315354306
Total Pages : 635 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Upconverting Nanomaterials by : Claudia Altavilla

Download or read book Upconverting Nanomaterials written by Claudia Altavilla and published by CRC Press. This book was released on 2016-10-03 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Upconverting Nanomaterials: Perspectives, Synthesis, and Applications serves as a powerful instrument that explores cutting-edge research knowledge on the topic of upconverting nanosystems, while simultaneously providing the necessary fundamental background for nonspecialist readers. The various aspects of upconverting materials are approached both from a theoretical point of view, particularly upconverting phenomenon, and a practical one. By presenting synthetic strategies, functionalization, production of core shell structures and nanocomposites, this book supplies PhD students, researchers, and scientists with a wealth of ideas they can apply to different fields of research. Thirty-five renowned scientists from around the world have collaborated to produce 11 chapters that help to "make a voyage" through the most important aspects of UPNPs, including syntheses, mechanism, functionalization, and applications.

Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials

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Author :
Publisher : Engineering Science Reference
ISBN 13 : 9781799885917
Total Pages : 2500 pages
Book Rating : 4.8/5 (859 download)

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Book Synopsis Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials by : Information Resources Management Association

Download or read book Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials written by Information Resources Management Association and published by Engineering Science Reference. This book was released on 2021 with total page 2500 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This reference of contributed chapters seeks to address not only how nanomaterials are created, used, or characterized, but also to apply this knowledge to the multidimensional industries, fields, and applications of nanomaterials and nanoscience by including topics such as both natural and manmade nanomaterials; the size, shape, reactivity, and other essential characteristics of nanomaterials; challenges and potential effects of using nanomaterials; and the advantages of nanomaterials with multidisciplinary uses"--

Nanoparticles in Lung Cancer Therapy - Recent Trends

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Author :
Publisher : Springer
ISBN 13 : 8132221753
Total Pages : 78 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Nanoparticles in Lung Cancer Therapy - Recent Trends by : Abhijit Bandyopadhyay

Download or read book Nanoparticles in Lung Cancer Therapy - Recent Trends written by Abhijit Bandyopadhyay and published by Springer. This book was released on 2014-11-14 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface properties and easy surface functionalization of nanoparticles enable early detection, diagnosis, imaging and treatment of lung cancer. The authors have elaborately presented how various nanoparticles (natural, semi synthetic and synthetic) may help in the treatment of lung cancer. They have also detailed works of various scientists who succeeded in developing effective nanoparticles and enabled very specific lung cancer therapy without any undesirable side effects and minimized death.