Surface Enhanced Raman Spectroscopy Biosensing And Diagnostic Technique For Healthcare Applications

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Surface Enhanced Raman Spectroscopy: Biosensing and Diagnostic Technique for Healthcare Applications

Author : Swati Jain
Publisher : Bentham Science Publishers
ISBN 13 : 9815039121
Total Pages : 263 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy: Biosensing and Diagnostic Technique for Healthcare Applications by : Swati Jain

Download or read book Surface Enhanced Raman Spectroscopy: Biosensing and Diagnostic Technique for Healthcare Applications written by Swati Jain and published by Bentham Science Publishers. This book was released on 2021-12-28 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques. This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing. Key Features: - Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS) - Provides a complete framework on SERS based biosensing with concise chapters - Focuses on different active molecules critical to SERS and associated developed nanoassemblies - Presents information about ongoing research on SERS imaging applications - Highlights bottlenecks of SERS technique in biosensing - Includes references for further reading This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.

Surface-Enhanced Raman Spectroscopy

Author : Marek Prochazka
Publisher : Springer
ISBN 13 : 3319239929
Total Pages : 230 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Surface-Enhanced Raman Spectroscopy by : Marek Prochazka

Download or read book Surface-Enhanced Raman Spectroscopy written by Marek Prochazka and published by Springer. This book was released on 2015-12-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.

Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy

Author : Yuling Wang
Publisher : Elsevier
ISBN 13 : 012823198X
Total Pages : 465 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy by : Yuling Wang

Download or read book Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy written by Yuling Wang and published by Elsevier. This book was released on 2021-09-17 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS and suitable nanomaterials for SERS application Gives an overview of the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics

Exploring the Challenges of Advancing Surface Enhanced Raman Spectroscopy-Based Biosensing From Research Laboratory to Clinics

Author : Owen Suyuan Liang
Publisher :
ISBN 13 :
Total Pages : 133 pages
Book Rating : 4.:/5 (119 download)

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Book Synopsis Exploring the Challenges of Advancing Surface Enhanced Raman Spectroscopy-Based Biosensing From Research Laboratory to Clinics by : Owen Suyuan Liang

Download or read book Exploring the Challenges of Advancing Surface Enhanced Raman Spectroscopy-Based Biosensing From Research Laboratory to Clinics written by Owen Suyuan Liang and published by . This book was released on 2020 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare has seen a big boon in technological advancement with the last few years with next-generation genome sequencing, robotics, artificial intelligence, and bioinformatics. While the origins of these breakthroughs are deeply rooted in biology, life sciences, and medical science, the new age of technological breakthrough require an interdisciplinary approach. Materials science itself is an interdisciplinary field, with a huge contribution of physics and chemistry, and within the past few decades, advances in nanotechnology has allowed integration into healthcare giving materials science a new emerging role. Such is the case with a vibrational spectroscopy technique called Surface Enhanced Raman Spectroscopy (SERS). SERS has the ability to measure the molecular bonds of the target analyte at the single molecular level. Yet, SERS is not a recognized spectrometry tool in healthcare. This dissertation examines the fundamental challenges that require a technique like SERS to transition from the academic research laboratories to clinical applications. While there are broad potential clinical applications, this dissertation focuses on the SERS measurement of diseases originating from cellular morphologies. The two main focal topics are cancer and microbiology research, where the proteome identification can provide new diagnostic and therapeutic treatment options. The first major section is about testing the capabilities of our group's unique graphene gold nanopyramid hybrid platform in controlled research laboratory environments. Varies cases of cancers are examined: lung, skin, and breast, through their various size, morphology, and proteomic differences. Afterwards, the field of microbiology is explored with bacteria and fungus species. The second major section involves the SERS's platform performance with clinical patient data. The first case study looks at the diagnosing meningitis from patients in China. The second case study looks at multidrug resistance detection of tuberculosis in rural Pakistan. The last major section tries to consolidate the major lessons in this journey of bringing SERS to clinical applications. In particular, this section tackles the main question of why a technique like SERS has not been fully recognized in clinics yet and brings the case to why our SERS hybrid platform is very close to it.

Surface Enhanced Raman Spectroscopy for Biophysical Applications

Author : Claudia Fasolato
Publisher : Springer
ISBN 13 : 3030035565
Total Pages : 167 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy for Biophysical Applications by : Claudia Fasolato

Download or read book Surface Enhanced Raman Spectroscopy for Biophysical Applications written by Claudia Fasolato and published by Springer. This book was released on 2018-12-05 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.

SERS for Point-of-care and Clinical Applications

Author : Andrew Fales
Publisher : Elsevier
ISBN 13 : 0128209100
Total Pages : 258 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis SERS for Point-of-care and Clinical Applications by : Andrew Fales

Download or read book SERS for Point-of-care and Clinical Applications written by Andrew Fales and published by Elsevier. This book was released on 2022-08-12 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical and point-of-care settings. Sections provide an overview of SERS biomedical applications, providing in-depth information about point-of-care and clinical applications of SERS using specific examples from current literature. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists and researchers in all related fields. Highlights point-of-care applications for SERS Covers the recent biomedical applications of SERS carried out by leaders in the field Includes chapters on SERS probes and labels and label-free uses of SERS

Surface-Enhanced Vibrational Spectroscopy

Author : Ricardo Aroca
Publisher : John Wiley & Sons
ISBN 13 : 9780470035658
Total Pages : 260 pages
Book Rating : 4.0/5 (356 download)

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Book Synopsis Surface-Enhanced Vibrational Spectroscopy by : Ricardo Aroca

Download or read book Surface-Enhanced Vibrational Spectroscopy written by Ricardo Aroca and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst

Surface Enhanced Raman Spectroscopy

Author : Sebastian Schlücker
Publisher : John Wiley & Sons
ISBN 13 : 3527633065
Total Pages : 97 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Surface Enhanced Raman Spectroscopy by : Sebastian Schlücker

Download or read book Surface Enhanced Raman Spectroscopy written by Sebastian Schlücker and published by John Wiley & Sons. This book was released on 2011-09-19 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems. From the contents: * Theory and practice of SERS * Analytical applications * SERS combined with other analytical techniques * Biophysical applications * Life science applications including various microscopies Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.

Surface-enhanced Raman Spectroscopy

Author : Vinay Bhardwaj
Publisher : Nova Science Publishers
ISBN 13 : 9781536153798
Total Pages : 284 pages
Book Rating : 4.1/5 (537 download)

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Book Synopsis Surface-enhanced Raman Spectroscopy by : Vinay Bhardwaj

Download or read book Surface-enhanced Raman Spectroscopy written by Vinay Bhardwaj and published by Nova Science Publishers. This book was released on 2019 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, we have seen spurring growth in academic and industrial interest in Raman spectroscopy and its modifications, in particular, Surface-Enhanced Raman Spectroscopy (SERS). This is evident by the number of SERS publications in the last decade, from 580 in 2005 to almost 2000 in 2014. There are now companies worldwide that are dedicated to manufacturing SERS substrate, sensors, and other SERS-based products. The miniaturization of Raman instrumentation from bulky and expensive bench-top designs to inexpensive handheld spectrometers has allowed SERS to be employed as an in situ detection technique. Some examples of the industrial success of Raman and SERS are rapid raw material identification (RMID), Process Analytical Technology (PAT) and drug screening in pharma and biotech industries, continuous surveillance of food, water, and environmental safety, and the diagnosis and continuous monitoring of diseases like cancer, diabetes, etc. This progress in translating Raman and SERS techniques into commercial use and commercial products is possible because of the close collaboration between scientists and engineers. However, the weak signals of Raman spectroscopy is an inherent limitation of the spontaneous Raman spectroscopy technique. Therefore, several modifications have been made, including but not limited to, surface-enhanced Raman spectroscopy (SERS), spatially offset Raman spectroscopy (SORS), transmission Raman spectroscopy (TRS), coherent anti-Stoke's Raman spectroscopy (CARS), and tip-enhanced Raman spectroscopy (TERS). Spontaneous Raman spectroscopy has become a one-of-a kind, portable, and affordable technology for in-situ detection and continuous monitoring in resource-limited-settings. The primary focus of this textbook is to try to cover the fundamentals in SERS methods of preparing substrates and sensors, and efficient spectral analysis approaches like chemometrics for diverse applications, listed in the paragraph above. However, with a goal to give a true picture to the audience when assessing the scope of spontaneous Raman and Surface-enhanced Raman for specific applications, we have briefly introduced industrially successful examples of other types of Raman spectroscopy techniques, such as SORS, TRS, and CARS.

Frontiers of Surface-Enhanced Raman Scattering

Author : Yukihiro Ozaki
Publisher : John Wiley & Sons
ISBN 13 : 111870357X
Total Pages : 466 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Frontiers of Surface-Enhanced Raman Scattering by : Yukihiro Ozaki

Download or read book Frontiers of Surface-Enhanced Raman Scattering written by Yukihiro Ozaki and published by John Wiley & Sons. This book was released on 2014-02-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors. Relevant to all those within the scientific community dealing with Raman Spectroscopy, i.e. physicists, chemists, biologists, material scientists, physicians and biomedical scientists. SERS applications are widely expanding and the technology is now used in the field of nanotechnologies, applications to biosystems, nonosensors, nanoimaging and nanoscience.

Principles of Surface-Enhanced Raman Spectroscopy

Author : Eric Le Ru
Publisher : Elsevier
ISBN 13 : 0080931553
Total Pages : 688 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Principles of Surface-Enhanced Raman Spectroscopy by : Eric Le Ru

Download or read book Principles of Surface-Enhanced Raman Spectroscopy written by Eric Le Ru and published by Elsevier. This book was released on 2008-11-17 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) Gives a comprehensive summary of the underlying physical concepts around SERS Provides a detailed analysis of plasmons and plasmonics

Health and Environmental Applications of Biosensing Technologies

Author : Murugan Veerapandian
Publisher : Elsevier
ISBN 13 : 0443190402
Total Pages : 480 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Health and Environmental Applications of Biosensing Technologies by : Murugan Veerapandian

Download or read book Health and Environmental Applications of Biosensing Technologies written by Murugan Veerapandian and published by Elsevier. This book was released on 2023-10-13 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: With emerging biological threats from pathogenic microorganisms and increasing environmental pollutants, it is essential to ensure the safety needs of individuals and the ecosystem are met. Modern materials science and engineering has evolved over the years to better develop devices to test abnormalities. Affordability, accessibility, and reliability of any analytical system is the prime necessity for a modern diagnostic application. Health and Environmental Applications of Biosensing Technologies: Clinical and Allied Health Science Perspective presents a detailed overview on biosensor design systems and optimal fabrication technologies to create a greater impact on various industries and help organizations break existing performance tradeoffs to deploy biosensor technologies across inter/transdisciplinary businesses. The book presents novel and emerging trends in biosensor design and healthcare applications focused on API detection, communicable/non-communicable disease diagnosis, food quality monitoring, agro-environmental analysis, bio-defense, and industrial pollutant sensing. In addition, wearable biosensors, commercial products, and safety regulations for biosensing technologies are summarized. Provides a fundamental understanding on biosensor system design, biomarkers for communicable/non-communicable diseases, and bioreceptor immobilization techniques Integrates information covering biosensing technologies for clinical diagnosis, API detection, industrial/environmental monitoring, agro-livestock healthcare, and disease control Provides information on principles, advanced trends, and approaches for wearable biosensors Covers market trends with biosensing technologies/products and their commercial challenges

Surface-Enhanced Raman Scattering

Author : Zhong-Qun Tian
Publisher : John Wiley & Sons Incorporated
ISBN 13 : 9780470068083
Total Pages : 400 pages
Book Rating : 4.0/5 (68 download)

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Book Synopsis Surface-Enhanced Raman Scattering by : Zhong-Qun Tian

Download or read book Surface-Enhanced Raman Scattering written by Zhong-Qun Tian and published by John Wiley & Sons Incorporated. This book was released on 2010-06-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.

The Use of Surface Enhanced Raman Spectroscopy (SERS) for Biomedical Applications

Author : Mustafa Habib Chowdhury
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (155 download)

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Book Synopsis The Use of Surface Enhanced Raman Spectroscopy (SERS) for Biomedical Applications by : Mustafa Habib Chowdhury

Download or read book The Use of Surface Enhanced Raman Spectroscopy (SERS) for Biomedical Applications written by Mustafa Habib Chowdhury and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies

Author : Ivano Alessandri
Publisher : Frontiers Media SA
ISBN 13 : 2889635538
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies by : Ivano Alessandri

Download or read book Surface Enhanced Raman Scattering: New Theoretical Approaches, Materials and Strategies written by Ivano Alessandri and published by Frontiers Media SA. This book was released on 2020-03-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surface Infrared and Raman Spectroscopy

Author : W. Suëtaka
Publisher : Springer Science & Business Media
ISBN 13 : 1489909427
Total Pages : 278 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Surface Infrared and Raman Spectroscopy by : W. Suëtaka

Download or read book Surface Infrared and Raman Spectroscopy written by W. Suëtaka and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: are intended to fill the gap between a manufacturer's handbook, and review articles that highlight the latest scientific developments. A fourth volume will deal with techniques for specimen handling, beam artifacts, and depth profiling. It will provide a compilation of methods that have proven useful for specimen handling and treatment, and it will also address the common artifacts and problems associated with the bombardment of solid sur faces by photons, electrons, and ions. A description will be given of methods for depth profiling. Surface characterization measurements are being used increasingly in di verse areas of science and technology. We hope that this series will be useful in ensuring that these measurements can be made as efficiently and reliably as possible. Comments on the series are welcomed, as are suggestions for volumes on additional topics. C. J. Powell Gaithersburg, Maryland A. W. Czandema Golden, Colorado D. M. Hercules Pittsburgh, Pennsylvania T. E. Madey New Brunswick, New Jersey J. T. Yates, Jr.

Surface and Tip-Enhanced Raman Scattering Spectroscopy

Author : Marek Prochazka
Publisher : Springer
ISBN 13 : 9789819758173
Total Pages : 0 pages
Book Rating : 4.7/5 (581 download)

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Book Synopsis Surface and Tip-Enhanced Raman Scattering Spectroscopy by : Marek Prochazka

Download or read book Surface and Tip-Enhanced Raman Scattering Spectroscopy written by Marek Prochazka and published by Springer. This book was released on 2024-10-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes recent progress in the mechanistic studies and applications of surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS). In this book, various novel techniques in SERS and TERS such as UV resonance TERS, electrochemical TERS, and three-dimensional SERS imaging are outlined. A number of new applications of SERS and TERS such as those to photonics, nanotechnology, microfluidics, and medical diagnosis along with future perspectives are also discussed. Finally, the applications of new data analysis, models, and machine learning in SERS and TERS studies are reviewed. The novelty of this book is the forming of a new bridge between the theory and applications. Also, the importance of chemical mechanism and that of semiconductor-enhanced Raman scattering is emphasized. The main audiences are researchers in academia, research institutes, companies, and graduate students looking for a comprehensive book on the latest studies of SERS and TERS.