Hacking Darwin

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Author :
Publisher : Sourcebooks, Inc.
ISBN 13 : 1492670103
Total Pages : 253 pages
Book Rating : 4.4/5 (926 download)

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Book Synopsis Hacking Darwin by : Jamie Metzl

Download or read book Hacking Darwin written by Jamie Metzl and published by Sourcebooks, Inc.. This book was released on 2019-04-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic engineering and its impact on the future of our species from leading geopolitical expert and technology futurist, Jamie Metzl. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. Enter the laboratories where scientists are turning science fiction into reality. In this captivating and thought-provoking nonfiction science book, Jamie Metzl delves into the ethical, scientific, political, and technological dimensions of genetic engineering, and shares how it will shape the course of human evolution. Cutting-edge insights into the field of genetic engineering and its implications for humanity's future Explores the transformative power of genetic technologies and their potential to reshape human life Examines the ethical considerations surrounding genetic engineering and the choices we face as a species Engaging narrative that delves into the scientific breakthroughs and real-world applications of genetic technologies Provides a balanced perspective on the promises and risks associated with genetic engineering Raises thought-provoking questions about the future of reproduction, human health, and our relationship with nature Drawing on his extensive background in genetics, national security, and foreign policy, Metzl paints a vivid picture of a world where advancements in technology empower us to take control of our own evolution, but also cautions against the pitfalls and ethical dilemmas that could arise if not properly managed. Hacking Darwin is a must-read for anyone interested in the intersection of science, technology, and humanity's future.

Space Science & Technology in China: A Roadmap to 2050

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642053424
Total Pages : 120 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Space Science & Technology in China: A Roadmap to 2050 by : Huadong Guo

Download or read book Space Science & Technology in China: A Roadmap to 2050 written by Huadong Guo and published by Springer Science & Business Media. This book was released on 2010-08-09 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: As one of the eighteen field-specific reports comprising the comprehensive scope of the strategic general report of the Chinese Academy of Sciences, this sub-report addresses long-range planning for developing science and technology in the field of space science. They each craft a roadmap for their sphere of development to 2050. In their entirety, the general and sub-group reports analyze the evolution and laws governing the development of science and technology, describe the decisive impact of science and technology on the modernization process, predict that the world is on the eve of an impending S&T revolution, and call for China to be fully prepared for this new round of S&T advancement. Based on the detailed study of the demands on S&T innovation in China's modernization, the reports draw a framework for eight basic and strategic systems of socio-economic development with the support of science and technology, work out China's S&T roadmaps for the relevant eight basic and strategic systems in line with China's reality, further detail S&T initiatives of strategic importance to China's modernization, and provide S&T decision-makers with comprehensive consultations for the development of S&T innovation consistent with China's reality. Supported by illustrations and tables of data, the reports provide researchers, government officials and entrepreneurs with guidance concerning research directions, the planning process, and investment. Founded in 1949, the Chinese Academy of Sciences is the nation's highest academic institution in natural sciences. Its major responsibilities are to conduct research in basic and technological sciences, to undertake nationwide integrated surveys on natural resources and ecological environment, to provide the country with scientific data and consultations for government's decision-making, to undertake government-assigned projects with regard to key S&T problems in the process of socio-economic development, to initiate personnel training, and to promote China's high-tech enterprises through its active engagement in these areas.

The Better Half

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Publisher : Farrar, Straus and Giroux
ISBN 13 : 1250174791
Total Pages : 288 pages
Book Rating : 4.2/5 (51 download)

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Book Synopsis The Better Half by : Dr. Sharon Moalem, MD, PhD

Download or read book The Better Half written by Dr. Sharon Moalem, MD, PhD and published by Farrar, Straus and Giroux. This book was released on 2020-04-07 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Guardian Book of the Week Longlisted for the PEN / E. O. Wilson Literary Science Writing Award An award-winning physician and scientist makes the game-changing case that genetic females are stronger than males at every stage of life Here are some facts: Women live longer than men. They have stronger immune systems. They're better at fighting cancer and surviving famine, and even see the world in a wider variety of colors. They are simply stronger than men at every stage of life. Why is this? And why are we taught the opposite? To find out, Dr. Sharon Moalem drew on his own medical experiences - treating premature babies in the neonatal intensive care unit; recruiting the elderly for neurogenetic studies; tending to HIV-positive orphans in Thailand - and tried to understand why in every instance men were consistently less likely to thrive. The answer, he discovered, lies in our genetics: two X chromosomes offer a powerful survival advantage. With clear, captivating prose that weaves together eye-opening research, case studies, diverse examples ranging from the behavior of honeybees to American pioneers, as well as experiences from his personal life and his own patients, Moalem explains why genetic females triumph over males when it comes to resiliency, intellect, stamina, immunity and much more. He also calls for a reconsideration of our male-centric, one-size-fits-all view of medical studies and even how we prescribe medications - a view that still sees women through the lens of men. Revolutionary and yet utterly convincing, The Better Half will make you see humanity and the survival of our species anew.

Genesis Code

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Author :
Publisher : Skyhorse
ISBN 13 : 162872465X
Total Pages : 365 pages
Book Rating : 4.6/5 (287 download)

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Book Synopsis Genesis Code by : Jamie Metzl

Download or read book Genesis Code written by Jamie Metzl and published by Skyhorse. This book was released on 2014-11-04 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blue Magic, the latest designer drug linked to a rash of overdoses, might explain the needle mark on the arm of a young woman found dead in her Kansas City apartment. But when Star reporter Rich Azadian digs deeper, the clues point to a far more explosive story: MaryLee Stock was a special protégée of evangelical megapastor and power broker Cobalt Becker, who is poised to deliver his followers and the presidency to a firebrand right-wing senator in the next election. When Azadian sets out to prove that MaryLee’s death was no accident and she may have been carrying Becker’s genetically enhanced baby, the stakes become life itself. In 2023 America—bankrupt, violently divided by the culture wars, and beholden to archrival China—the rules of the game are complicated. With the danger mounting, the dead bodies of young women piling up, Chinese agents circling, and the US Department of National Competitiveness moving in to quash his investigation, Azadian’s only option is to go rogue, assemble a team of brilliant misfits like himself, and begin the fight of his life to find out who is killing these women and why, and if any others like them may still be alive. Skyhorse Publishing, as well as our Arcade, Yucca, and Good Books imprints, are proud to publish a broad range of books for readers interested in fiction—novels, novellas, political and medical thrillers, comedy, satire, historical fiction, romance, erotic and love stories, mystery, classic literature, folklore and mythology, literary classics including Shakespeare, Dumas, Wilde, Cather, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

A Nation of Guinea Pigs

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Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.:/5 (39 download)

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Book Synopsis A Nation of Guinea Pigs by : Marshall S. Shapo

Download or read book A Nation of Guinea Pigs written by Marshall S. Shapo and published by . This book was released on 1979 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Present at the Creation: My Years in the State Department

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 1324064609
Total Pages : 858 pages
Book Rating : 4.3/5 (24 download)

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Book Synopsis Present at the Creation: My Years in the State Department by : Dean Acheson

Download or read book Present at the Creation: My Years in the State Department written by Dean Acheson and published by W. W. Norton & Company. This book was released on 1987-09-17 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize With deft portraits of many world figures, Dean Acheson analyzes the processes of policy making, the necessity for decision, and the role of power and initiative in matters of state. Acheson (1893–1971) was not only present at the creation of the postwar world, he was one of its chief architects. He joined the Department of State in 1941 as Assistant Secretary of State for Economic Affairs and, with brief intermissions, was continuously involved until 1953, when he left office as Secretary of State at the end of the Truman years. Throughout that time Acheson's was one of the most influential minds and strongest wills at work. It was a period that included World War II, the reconstruction of Europe, the Korean War, the development of nuclear power, the formation of the United Nations and NATO. It involved him at close quarters with a cast that starred Truman, Roosevelt, Churchill, de Gaulle, Marshall, MacArthur, Eisenhower, Attlee, Eden Bevin, Schuman, Dulles, de Gasperi, Adenauer, Yoshida, Vishinsky, and Molotov.

Editing Humanity

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Publisher : Simon and Schuster
ISBN 13 : 1643133942
Total Pages : 411 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Editing Humanity by : Kevin Davies

Download or read book Editing Humanity written by Kevin Davies and published by Simon and Schuster. This book was released on 2020-10-06 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

A Connectionist Machine for Genetic Hillclimbing

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461319978
Total Pages : 268 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis A Connectionist Machine for Genetic Hillclimbing by : David Ackley

Download or read book A Connectionist Machine for Genetic Hillclimbing written by David Ackley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the "black box function optimization" problem, a search strategy is required to find an extremal point of a function without knowing the structure of the function or the range of possible function values. Solving such problems efficiently requires two abilities. On the one hand, a strategy must be capable of learning while searching: It must gather global information about the space and concentrate the search in the most promising regions. On the other hand, a strategy must be capable of sustained exploration: If a search of the most promising region does not uncover a satisfactory point, the strategy must redirect its efforts into other regions of the space. This dissertation describes a connectionist learning machine that produces a search strategy called stochastic iterated genetic hillclimb ing (SIGH). Viewed over a short period of time, SIGH displays a coarse-to-fine searching strategy, like simulated annealing and genetic algorithms. However, in SIGH the convergence process is reversible. The connectionist implementation makes it possible to diverge the search after it has converged, and to recover coarse-grained informa tion about the space that was suppressed during convergence. The successful optimization of a complex function by SIGH usually in volves a series of such converge/diverge cycles.

Intervention

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Author :
Publisher : You Lulu Incorporated
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Intervention by : Denise Caruso

Download or read book Intervention written by Denise Caruso and published by You Lulu Incorporated. This book was released on 2006 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: INTERVENTION challenges two of the most sacred tenets of modern society, innovation and technology, from the perspective of the unique risks they present. Using genetic engineering as its model, it paints a vivid picture of the scientific uncertainties that biotech risk evaluations dismiss or ignore, and lays bare the power and money conflicts between academia, industry and regulators that have sped these risky innovations to the market. Intervention champions an alternative method for assessing the risks of technology, developed by the world's top risk experts, that can eliminate such conflicts, help regain public trust in science and government, and drive research and development toward more useful, safer products.

Work Mate Marry Love

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Publisher : Macmillan + ORM
ISBN 13 : 0374716218
Total Pages : 305 pages
Book Rating : 4.3/5 (747 download)

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Book Synopsis Work Mate Marry Love by : Debora L. Spar

Download or read book Work Mate Marry Love written by Debora L. Spar and published by Macmillan + ORM. This book was released on 2020-08-18 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A crucial guide to life before—and after—Tinder, IVF, and robots. What will happen to our notions of marriage and parenthood as reproductive technologies increasingly allow for newfangled ways of creating babies? What will happen to our understanding of gender as medical advances enable individuals to transition from one set of sexual characteristics to another, or to remain happily perched in between? What will happen to love and sex and romance as our relationships migrate from the real world to the Internet? Can people fall in love with robots? Will they? In short, what will happen to our most basic notions of humanity as we entangle our lives and emotions with the machines we have created? In Work Mate Marry Love, Harvard Business School professor and former Barnard College president Debora L. Spar offers an incisive and provocative account of how technology has transformed our intimate lives in the past, and how it will do so again in the future. Surveying the course of history, she shows how marriage as we understand it resulted from the rise of agriculture, and that the nuclear family emerged with the industrial revolution. In their day, the street light, the car, and later the pill all upended courtship and sex. Now, as we enter an era of artificial intelligence and robots, how will our deepest feelings and attachments evolve? In the past, the prevailing modes of production produced a world dominated by heterosexual, mostly-monogamous, two-parent families. In the future, however, these patterns are almost certain to be reshaped, creating entirely new norms for sex and romance, and for the construction of families and the raising of children. Steering clear of both techno-euphoria and alarmism, Spar offers a bold and inclusive vision of how our lives might be changed for the better.

CRISPR People

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Author :
Publisher : MIT Press
ISBN 13 : 0262543885
Total Pages : 395 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis CRISPR People by : Henry T. Greely

Download or read book CRISPR People written by Henry T. Greely and published by MIT Press. This book was released on 2022-03-01 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.

Life as We Made It

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Publisher : Basic Books
ISBN 13 : 1541644158
Total Pages : 313 pages
Book Rating : 4.5/5 (416 download)

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Book Synopsis Life as We Made It by : Beth Shapiro

Download or read book Life as We Made It written by Beth Shapiro and published by Basic Books. This book was released on 2021-10-19 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the first dog to the first beefalo, from farming to CRISPR, the human history of remaking nature When the 2020 Nobel Prize was awarded to the inventors of CRISPR, the revolutionary gene-editing tool, it underlined our amazing and apparently novel powers to alter nature. But as biologist Beth Shapiro argues in Life as We Made It, this phenomenon isn’t new. Humans have been reshaping the world around us for ages, from early dogs to modern bacteria modified to pump out insulin. Indeed, she claims, reshaping nature—resetting the course of evolution, ours and others’—is the essence of what our species does. In exploring our evolutionary and cultural history, Shapiro finds a course for the future. If we have always been changing nature to help us survive and thrive, then we need to avoid naive arguments about how we might destroy it with our meddling, and instead ask how we can meddle better. Brilliant and insightful, Life as We Made It is an essential book for the decades to come.

Burn-in

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Publisher : Mariner Books
ISBN 13 : 1328637239
Total Pages : 437 pages
Book Rating : 4.3/5 (286 download)

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Book Synopsis Burn-in by : P. W. Singer

Download or read book Burn-in written by P. W. Singer and published by Mariner Books. This book was released on 2020 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: An FBI agent teams up with the first police robot to hunt a shadowy terrorist in this gripping technothriller--and fact-based tour of tomorrow--from the authors of Ghost Fleet America is on the brink of a revolution. AI and robotics have realized science fiction's dreams, but have also taken millions of jobs and left many citizens fearful that the future is leaving them behind. After narrowly averting a bombing at Washington's Union Station, FBI Special Agent Lara Keegan receives a new assignment: to field test the first police robot. In the wake of a series of shocking catastrophes, the two find themselves investigating a conspiracy whose mastermind is using cutting-edge tech to rip the nation apart. To stop this new breed of terrorist, Keegan's only hope is to forge a new kind of partnership. With every tech, trend, and scene drawn from the real world, Burn-In blends a technothriller's excitement with nonfiction's insight to illuminate the darkest corners of our chilling tomorrow.

Eternal Sonata

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Author :
Publisher : Arcade
ISBN 13 : 9781628729887
Total Pages : 0 pages
Book Rating : 4.7/5 (298 download)

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Book Synopsis Eternal Sonata by : Jamie Metzl

Download or read book Eternal Sonata written by Jamie Metzl and published by Arcade. This book was released on 2018-10-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A few dead bodies are a small price to pay in the quest for immortality. In 2025 America, it’s hardly news when a renowned octogenarian scientist dying of cancer disappears from a local hospice, but when Kansas City Star reporter Rich Azadian begins to dig, he discovers that other elderly scientists around the world have also vanished recently—all terminally ill and receiving the same experimental treatment from a global health company. His investigation leads him to the reclusive Noam Heller, a brilliant researcher exploring new technologies to reverse-age cancer and other cells. Using revolutionary stem cell treatments and snippets of DNA from rare, immortal Arctic jellyfish, his breakthrough promises the genetic equivalent of the fountain of youth. But when Heller is murdered and his lab destroyed, Rich and his girlfriend Antonia become targets themselves. With the local police and federal authorities failing to see the big picture, he realizes he must take matters into his own hands to survive and stop the killing. His only hope is to mobilize his network of brilliant misfits and infiltrate the vast and lethal race—among cutthroat corporations, national intelligence services, rogue scientists, and a mysterious international organization—to control the new technologies and perhaps the secret of life itself. Skyhorse Publishing, as well as our Arcade, Yucca, and Good Books imprints, are proud to publish a broad range of books for readers interested in fiction—novels, novellas, political and medical thrillers, comedy, satire, historical fiction, romance, erotic and love stories, mystery, classic literature, folklore and mythology, literary classics including Shakespeare, Dumas, Wilde, Cather, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

The Next 500 Years

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Author :
Publisher : MIT Press
ISBN 13 : 0262543842
Total Pages : 295 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis The Next 500 Years by : Christopher E. Mason

Download or read book The Next 500 Years written by Christopher E. Mason and published by MIT Press. This book was released on 2022-04-12 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: An argument that we have a moral duty to explore other planets and solar systems--because human life on Earth has an expiration date. Inevitably, life on Earth will come to an end, whether by climate disaster, cataclysmic war, or the death of the sun in a few billion years. To avoid extinction, we will have to find a new home planet, perhaps even a new solar system, to inhabit. In this provocative and fascinating book, Christopher Mason argues that we have a moral duty to do just that. As the only species aware that life on Earth has an expiration date, we have a responsibility to act as the shepherd of life-forms--not only for our species but for all species on which we depend and for those still to come (by accidental or designed evolution). Mason argues that the same capacity for ingenuity that has enabled us to build rockets and land on other planets can be applied to redesigning biology so that we can sustainably inhabit those planets. And he lays out a 500-year plan for undertaking the massively ambitious project of reengineering human genetics for life on other worlds. As they are today, our frail human bodies could never survive travel to another habitable planet. Mason describes the toll that long-term space travel took on astronaut Scott Kelly, who returned from a year on the International Space Station with changes to his blood, bones, and genes. Mason proposes a ten-phase, 500-year program that would engineer the genome so that humans can tolerate the extreme environments of outer space--with the ultimate goal of achieving human settlement of new solar systems. He lays out a roadmap of which solar systems to visit first, and merges biotechnology, philosophy, and genetics to offer an unparalleled vision of the universe to come.

The Genesis Machine

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Author :
Publisher : Hachette UK
ISBN 13 : 1541797930
Total Pages : 368 pages
Book Rating : 4.5/5 (417 download)

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Book Synopsis The Genesis Machine by : Amy Webb

Download or read book The Genesis Machine written by Amy Webb and published by Hachette UK. This book was released on 2022-02-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Named one of The New Yorker's BEST BOOKS OF 2022 SO FAR The next frontier in technology is inside our own bodies. Synthetic biology will revolutionize how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves. This fast-growing field—which uses computers to modify or rewrite genetic code—has created revolutionary, groundbreaking solutions such as the mRNA COVID vaccines, IVF, and lab-grown hamburger that tastes like the real thing. It gives us options to deal with existential threats: climate change, food insecurity, and access to fuel. But there are significant risks. Who should decide how to engineer living organisms? Whether engineered organisms should be planted, farmed, and released into the wild? Should there be limits to human enhancements? What cyber-biological risks are looming? Could a future biological war, using engineered organisms, cause a mass extinction event? Amy Webb and Andrew Hessel’s riveting examination of synthetic biology and the bioeconomy provide the background for thinking through the upcoming risks and moral dilemmas posed by redesigning life, as well as the vast opportunities waiting for us on the horizon.

The Depths of the Sea

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Author :
Publisher : Macmillan + ORM
ISBN 13 : 1466864222
Total Pages : 286 pages
Book Rating : 4.4/5 (668 download)

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Book Synopsis The Depths of the Sea by : Jamie Metzl

Download or read book The Depths of the Sea written by Jamie Metzl and published by Macmillan + ORM. This book was released on 2014-02-04 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's 1979 and Morgan O'Reilly, a dispirited CIA desk officer, is desperately trying to bury his memories. Sent to Cambodia as a Marine and then as a CIA operative during the Vietnam War, he had been given the unlikely task of pulling together a secret spy unit of orphaned street children. At the end of the war, he was only able to get one child out of the country, his surrogate son, Sophal. Years later, Sophal, now a CIA agent, disappears on a secret mission in the Cambodian refugee camps in Thailand. Tom Dillon, the dashing young superstar of the White House foreign policy staff, asks O'Reilly to find Sophal and bring him home. O'Reilly's search takes him deeper and deeper into the politics of the Thai-Cambodian border and finally into the deadly Khmer Rouge zone - a place where all foreigners are forbidden from entering and where cruelty and death are omnipresent. Filled with the fascinating workings of the refugee camps, the life or death politics of Washington, DC, and the inner workings of the personalities that are drawn to such extreme circumstances, Jamie Metzl's The Depths of the Sea is a thriller that both entertains and educates.