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Study Of The Endocrine And Metabolic Dysfunction And Assessment Of Hormonal Interventions In A Novel In Vivo Experimental Model Of Critical Illness
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Book Synopsis Study of the Endocrine and Metabolic Dysfunction and Assessment of Hormonal Interventions in a Novel in Vivo Experimental Model of Critical Illness by : Frank Weekers
Download or read book Study of the Endocrine and Metabolic Dysfunction and Assessment of Hormonal Interventions in a Novel in Vivo Experimental Model of Critical Illness written by Frank Weekers and published by Leuven University Press. This book was released on 2003 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mechanisms of Growth Hormone- and Insulin-induced Alterations in Metabolism During Critical Illness by : Dieter Mesotten
Download or read book Mechanisms of Growth Hormone- and Insulin-induced Alterations in Metabolism During Critical Illness written by Dieter Mesotten and published by Leuven University Press. This book was released on 2003 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. In this thesis attention will be focuses on the mechanisms by which growth hormone and insulin modify some major metabolic pathways, in light of their opposite effects on outcome of critical iliness. Chapter 1 comprises a bri"
Book Synopsis Measurement of CYP 3A4 and P-GP Activity in Vivo Using Dynamic Breath and Urine Analysis by : Wim Lemahieu
Download or read book Measurement of CYP 3A4 and P-GP Activity in Vivo Using Dynamic Breath and Urine Analysis written by Wim Lemahieu and published by Leuven University Press. This book was released on 2005 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Contents include: General introduction, Measurement of intestinal CYP3A4 and P-Glycoprotein activity by a combined oral and intravenous 14C-Erythromycin breath and urine test, Alterations of CYP3A4 and P-Glycoprotein activity in vivo with time in renal graft recipients, CYP3A4 and P-Glycoprotein activity in healthy controls and transplant patients on cyclosporine vs. Tacrolimus vs. Sirolimus, Impact of gastric acid suppressants on cytochrome P450 3A4 and P-Glycoprotein: consequences for FK506 assimilation, Diarrhoea after transplantation: impact on cytochrome P4503A4/P-Glycoprotein and assimilation of calcineurin inhibitors, Discussion.
Book Synopsis Experimental Evaluation of the Host Immune Response to Xenogenic Bio-derived Collagen Grafts in Rodent Models by : Fang Zheng
Download or read book Experimental Evaluation of the Host Immune Response to Xenogenic Bio-derived Collagen Grafts in Rodent Models written by Fang Zheng and published by Leuven University Press. This book was released on 2006-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings by : An van Nieuwenhuyse
Download or read book A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings written by An van Nieuwenhuyse and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modulation of Androgen Receptor Activity by P160 Coactivators and a Study of Environmental Contaminants by : Valerie Christiaens
Download or read book Modulation of Androgen Receptor Activity by P160 Coactivators and a Study of Environmental Contaminants written by Valerie Christiaens and published by Leuven University Press. This book was released on 2005 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development, growth and survival of eukaryotic organisms require the proper regulation of tens of thousands of genes. Therefore, a correct temporal and spatial expression of genes is crucial. These expression patterns are controlled by a wide variety of mechanisms, but a major level of gene expression occurs at the transcription initiation process. In this part, the basic mechanisms of eukaryotic gene transcription will be discussed. Contents include: 1) General Introduction, 2) Characterization of the two coactivator interacting surfaces of the androgen receptor and their relative role in transcriptional control, 3) Screening for environmental (anti)androgenic activity, 4) Detection of endocrine disrupting activities in pesticides and polychlorinated biphenyls, and 5) General Discussion / Future Perspectives.
Book Synopsis Cancer Risk Assessment at the Workplace by : Lode Godderis
Download or read book Cancer Risk Assessment at the Workplace written by Lode Godderis and published by Leuven University Press. This book was released on 2006-09 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Complex Motion Processing in the Human Cerebral Cortex as Studied by Functional Imaging by : Hendrik Peuskens
Download or read book Complex Motion Processing in the Human Cerebral Cortex as Studied by Functional Imaging written by Hendrik Peuskens and published by Leuven University Press. This book was released on 2004-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physiological Study of Presenilins and Baces, Two Proteases Involved in the Pathogenesis of Alzheimer's Disease by : Jos Tournoy
Download or read book Physiological Study of Presenilins and Baces, Two Proteases Involved in the Pathogenesis of Alzheimer's Disease written by Jos Tournoy and published by Leuven University Press. This book was released on 2006 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biochemical and Immuno-Histochemical Analysis of APP-Processing and Amyloid Pathology in Single and Multiple Transgenic Mice as Models for Alzheimer's Disease by : Tom V. Dooren
Download or read book Biochemical and Immuno-Histochemical Analysis of APP-Processing and Amyloid Pathology in Single and Multiple Transgenic Mice as Models for Alzheimer's Disease written by Tom V. Dooren and published by Leuven University Press. This book was released on 2006-09 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ciz As a Fusion Partner for Tet-proteins in Leukemia by : Hilde Janssen
Download or read book Ciz As a Fusion Partner for Tet-proteins in Leukemia written by Hilde Janssen and published by Leuven University Press. This book was released on 2006-12-30 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genetic Analysis of Herpesvirus Entry Receptors and Host Susceptibility to Herpes Simplex Virus Infection by : Frank Struyf
Download or read book Genetic Analysis of Herpesvirus Entry Receptors and Host Susceptibility to Herpes Simplex Virus Infection written by Frank Struyf and published by Leuven University Press. This book was released on 2004-09 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biochemical Characterization and Validation of the Yeast Saccharomyces Cerevisiae as Model System for the Function of Human Protein Tau by : Tom Vandebroek
Download or read book Biochemical Characterization and Validation of the Yeast Saccharomyces Cerevisiae as Model System for the Function of Human Protein Tau written by Tom Vandebroek and published by Leuven University Press. This book was released on 2006-09 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Human Airway Smooth Muscle Cells by : Wim Wuyts
Download or read book Human Airway Smooth Muscle Cells written by Wim Wuyts and published by Leuven University Press. This book was released on 2003 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Because of the worldwide burden of bronchial asthma and the recent increase in the use of lung transplantation as a treatment for end-stage lung disease, the importance of chronic inflammatory airway diseases, such as asthma "
Book Synopsis Structure-function Relationship of K+ Ion Channel Toxins by : Isabelle Huys
Download or read book Structure-function Relationship of K+ Ion Channel Toxins written by Isabelle Huys and published by Leuven University Press. This book was released on 2004 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Many fundamental processes underlying nerve and muscle excitation, hormone secretion, learning and memory, cell proliferation, sensory transduction and regulation of blood pressure and osmotic balance, are attributed to a div"
Book Synopsis Characterization of the Presenilin 1-Telencephalin Interaction and Implications for Alzheimer's Disease by : Cary Esselens
Download or read book Characterization of the Presenilin 1-Telencephalin Interaction and Implications for Alzheimer's Disease written by Cary Esselens and published by Leuven University Press. This book was released on 2005 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fatty Acid Synthase by : Ellen De Schrijver
Download or read book Fatty Acid Synthase written by Ellen De Schrijver and published by Leuven University Press. This book was released on 2005 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty acid synthase (FAS) is a key lipogenic enzyme catalyzing the terminal steps in the synthesis of fatty acids. In the majority of normal tissues, FAS expression is low. In many human cancers, however, including cancer of the prostate, FAS expression and FAS activity are very high. As shown in the laboratory, overexpression of FAS in tumor cells is part of a more general and coordinate upregulation of multiple lipogenic genes caused, at least in part, by activation of sterol regulatory element binding proteins (SREBPs), transcription factors that play a key role in cellular lipid homeostasis. The mechanisms underlying the activation of the SREBP pathway and the increase in lipogenesis in tumor cells as well as the ultimate biological significance of this phenomenon remain poorly understood. Nonetheless there is evidence that overexpression of lipogenic genes occurs early in tumor development and that the degree of overexpression correlates with increasing tumor grade. Moreover, a number of studies suggest that inhibition of FAS selectively reduces proliferation of tumor cells and causes apoptosis, implying that FAS and other lipogenic enzymes may constitute interesting targets for antineoplastic therapy.