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Studies Toward The Synthesis Of Halichlorine And Pinnaic Acid
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Book Synopsis Studies Toward the Synthesis of Halichlorine and Pinnaic Acid by : Eric A. Korf
Download or read book Studies Toward the Synthesis of Halichlorine and Pinnaic Acid written by Eric A. Korf and published by . This book was released on 2006 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three approaches toward the core of halichlorine and pinnaic acid are described. The first approach entails a racemic transannular nitrone-olefin [3+2] cycloaddition from nitrone 238. Construction of the nitrone 238 began with aldehyde 241. Another key feature in this route involved a ring-closing metathesis for the formation of a 14-membered ring. The route ended upon formation of a key diol 237. The second approach incorporated the C14 methyl group at an early stage to probe its influence upon an intramolecular nitrone-olefin [3+2] cycloaddition. The approach began with dithiane 258. A key feature in the second plan involved asymmetric induction at the C5 carbon through a conjugate addition of an azide to an [alpha, beta]-unsaturated imide to form azide 290 with both excellent yield and stereocontrol for this addition. The route was advanced to oxaziridine 299. Conversion of 299 to the nitrone 300 and ultimately the intramolecular nitrone-olefin [3+2] cycloaddition was unsuccessful. The third and final approach involved using the basic plan of our first successful approach and employing the asymmetric induction of the second approach. This blending of strategies led to an asymmetric intermediate that links up with the first approach. The route began with dithiane 258. Again, the use of an azide addition to a [alpha, beta]-unsaturated imide led to azide 309. Upon formation of the 14-membered lactone, the azide function was first reduced and protected as carbamate 320 which in turn, increased the yield substantially over this same transformation from the first route. Amine 318 now stands ready to complete a formal synthesis of halichlorine and pinnaic acid.
Book Synopsis Studies Towards the Total Synthesis of Halichlorine and Pinnaic Acid by : Louise G. Arini
Download or read book Studies Towards the Total Synthesis of Halichlorine and Pinnaic Acid written by Louise G. Arini and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Studies Toward Halichlorine and Pinnaic Acid by : Jennifer Lori Koviach
Download or read book Synthetic Studies Toward Halichlorine and Pinnaic Acid written by Jennifer Lori Koviach and published by . This book was released on 1999 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthetic Studies Towards Pinnaic Acid and Halichlorine by : Yang Sunghyun
Download or read book Synthetic Studies Towards Pinnaic Acid and Halichlorine written by Yang Sunghyun and published by . This book was released on 2009 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Total Synthesis of Halichlorine, Pinnaic Acid and Tauropinnaic Acid by : Hamish Saul Christie
Download or read book Total Synthesis of Halichlorine, Pinnaic Acid and Tauropinnaic Acid written by Hamish Saul Christie and published by . This book was released on 2004 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Part A - Studies Towards the Spirocyclic Core of Halichlorine and Pinnaic Acid ;Part B - Synthesis and in Vitro Evaluation of New Cholesterol Absorption Inhibitors by : Lisbet Kværnø
Download or read book Part A - Studies Towards the Spirocyclic Core of Halichlorine and Pinnaic Acid ;Part B - Synthesis and in Vitro Evaluation of New Cholesterol Absorption Inhibitors written by Lisbet Kværnø and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies Towards the Syntheses of Halichlorine and the Pinnaic Acids by : Camille Gignoux
Download or read book Studies Towards the Syntheses of Halichlorine and the Pinnaic Acids written by Camille Gignoux and published by . This book was released on 2012 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phycotoxins written by Luis M. Botana and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phycotoxins: Chemistry and Biochemistry presents the most updated information available on phycotoxins. Major emphases are given to chemistry and biochemistry, while minor emphases are given to the aspects of origin, toxicology, or analytical methodology. The book discusses 16 phycotoxins, 7 on those affecting the nervous systems, 4 affecting other body systems; and 4 with undefined targets. An alphabetical listing of toxins presented includes: Azaspiracids; Brevetoxins; Cyanobacterial toxins; Domoic acid; Gambierols; Gymnodimines, prorocentrolides, spirolides, pinnatoxins and cyclic imines in general; Maitotoxin; Okadaic acid and dinophysistoxins; Palytoxins and ostreocins; Pectenotoxins; Polycavernosides; and Yessotoxins. In addition, several mechanistic aspects of newer or emerging toxins are covered such as amphidinols or gymnocine. Information presented and coverage of each toxin follows the following distribution: background and toxicology (10%); chemistry, biochemistry and metabolism (75%); mechanism of action (10%); and analytical methodology (5%). The detailed information on chemistry in Phycotoxins: Chemistry and Biochemistry provides investigators, regulators, food technologists and toxicologists an updated basis on which research in other areas such as toxicology, mechanism of action, analytical methodology and pharmacology can be successfully developed and expanded.
Book Synopsis Strategies and Tactics in Organic Synthesis by : Michael Harmata
Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2012 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field.
Download or read book Hominatio written by M. Volkan Kisakürek and published by John Wiley & Sons. This book was released on 2001 with total page 1010 pages. Available in PDF, EPUB and Kindle. Book excerpt: The historical achievements in organic natural product synthesis can be recognized most clearly in the research accomplishments of Albert Eschenmoser. For example, his work on the chemical synthesis of vitamin B12 defined the frontier in organic natural product synthesis and profoundly influenced the science of organic chemistry. In addition to revealing the beautiful reaction pathways leading to compounds of great biochemical significance, Albert Eschenmoser has contributed innovative methods of outstanding utility for organic synthesis. Few individuals have so fundamentally influenced the science of organic chemistry as Albert Eschenmoser has. Over the years, a sizable fraction of Albert Eschenmoser′s work has been published in Helvetica Chimica Acta, hence the decision of the Editor to produce a special issue of the journal on the occasion of Albert Eschenmoser′s 75th birthday, celebrated on August 5, 2000. The highly impressive set of 67 original research papers submitted in response to the Editor′s invitation could not, for obvious technical reasons, be accommodated in a single issue and were thus divided over the August and September issues. The international reaction to this tribute has been so overwhelmingly enthusiastic that the two issues have been combined in this single volume for separate publication.
Book Synopsis American Doctoral Dissertations by :
Download or read book American Doctoral Dissertations written by and published by . This book was released on 1998 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molluscs written by Guido Cimino and published by Springer Science & Business Media. This book was released on 2007-02-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book on molluscs as sources for pharmaceutical drugs. Marine molluscs are very promising candidates for a wide range of biotechnological applications. For example, they possess analgesic drugs more potent than morphine and very effective anticancer agents. International experts provide coverage of the most stimulating topics related to molluscs. This knowledge of their history and current studies opens the door to the future.
Book Synopsis Proceedings of the National Academy of Sciences of the United States of America by : National Academy of Sciences (U.S.).
Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.). and published by . This book was released on 2004 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards by :
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2006 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theses on any subject submitted by the academic libraries in the UK and Ireland.
Book Synopsis Molecular Rearrangements in Organic Synthesis by : Christian M. Rojas
Download or read book Molecular Rearrangements in Organic Synthesis written by Christian M. Rojas and published by John Wiley & Sons. This book was released on 2015-10-26 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry
Download or read book 有機合成化学協会誌 written by and published by . This book was released on 2000 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:
