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Finding What Works in Health Care

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309164257
Total Pages : 267 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Finding What Works in Health Care by : Institute of Medicine

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Handbook of EHealth Evaluation

Author : Francis Yin Yee Lau
Publisher :
ISBN 13 : 9781550586015
Total Pages : 487 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Handbook of EHealth Evaluation by : Francis Yin Yee Lau

Download or read book Handbook of EHealth Evaluation written by Francis Yin Yee Lau and published by . This book was released on 2016-11 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: To order please visit https://onlineacademiccommunity.uvic.ca/press/books/ordering/

Systematic Reviews in Educational Research

Author : Olaf Zawacki-Richter
Publisher : Springer Nature
ISBN 13 : 3658276029
Total Pages : 175 pages
Book Rating : 4.6/5 (582 download)

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Book Synopsis Systematic Reviews in Educational Research by : Olaf Zawacki-Richter

Download or read book Systematic Reviews in Educational Research written by Olaf Zawacki-Richter and published by Springer Nature. This book was released on 2019-11-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this open access edited volume, international researchers of the field describe and discuss the systematic review method in its application to research in education. Alongside fundamental methodical considerations, reflections and practice examples are included and provide an introduction and overview on systematic reviews in education research.

Cochrane Handbook for Systematic Reviews of Interventions

Author : Julian P. T. Higgins
Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

An Introduction to Systematic Reviews

Author : David Gough
Publisher : SAGE
ISBN 13 : 1446289362
Total Pages : 382 pages
Book Rating : 4.4/5 (462 download)

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Book Synopsis An Introduction to Systematic Reviews by : David Gough

Download or read book An Introduction to Systematic Reviews written by David Gough and published by SAGE. This book was released on 2012-03-22 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre.

Systematic Approaches to a Successful Literature Review

Author : Andrew Booth
Publisher : SAGE
ISBN 13 : 1473952816
Total Pages : 366 pages
Book Rating : 4.4/5 (739 download)

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Book Synopsis Systematic Approaches to a Successful Literature Review by : Andrew Booth

Download or read book Systematic Approaches to a Successful Literature Review written by Andrew Booth and published by SAGE. This book was released on 2016-05-28 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showing you how to take a structured and organized approach to a wide range of literature review types, this book helps you to choose which approach is right for your research. Packed with constructive tools, examples, case studies and hands-on exercises, the book covers the full range of literature review techniques. New to This Edition: Full re-organization takes you step-by-step through the process from beginning to end New chapter showing you how to choose the right method for your project Practical guidance on integrating qualitative and quantitative data New coverage of rapid reviews Comprehensive inclusion of literature review tools, including concept analysis, scoping and mapping With an emphasis on the practical skills, this guide is essential for any student or researcher needing to get from first steps to a successful literature review.

Evidence-based Nursing Care Guidelines

Author : Betty J. Ackley
Publisher : Elsevier Health Sciences
ISBN 13 : 032304624X
Total Pages : 1011 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Evidence-based Nursing Care Guidelines by : Betty J. Ackley

Download or read book Evidence-based Nursing Care Guidelines written by Betty J. Ackley and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 1011 pages. Available in PDF, EPUB and Kindle. Book excerpt: From an internationally respected team of clinical and research experts comes this groundbreaking book that synthesizes the body of nursing research for 192 common medical-surgical interventions. Ideal for both nursing students and practicing nurses, this collection of research-based guidelines helps you evaluate and apply the latest evidence to clinical practice.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Author : Mark Elwood
Publisher : OUP Oxford
ISBN 13 : 0191004944
Total Pages : 615 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Critical Appraisal of Epidemiological Studies and Clinical Trials by : Mark Elwood

Download or read book Critical Appraisal of Epidemiological Studies and Clinical Trials written by Mark Elwood and published by OUP Oxford. This book was released on 2007-02-22 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Meta-Ethnography

Author : George W. Noblit
Publisher : SAGE
ISBN 13 : 9780803930230
Total Pages : 112 pages
Book Rating : 4.9/5 (32 download)

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Book Synopsis Meta-Ethnography by : George W. Noblit

Download or read book Meta-Ethnography written by George W. Noblit and published by SAGE. This book was released on 1988-02 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can ethnographic studies be generalized, in contrast to concentrating on the individual case? Noblit and Hare propose a new method for synthesizing from qualitative studies: meta-ethnography. After citing the criteria to be used in comparing qualitative research projects, the authors define the ways these can then be aggregated to create more cogent syntheses of research. Using examples from numerous studies ranging from ethnographic work in educational settings to the Mead-Freeman controversy over Samoan youth, Meta-Ethnography offers useful procedural advice from both comparative and cumulative analyses of qualitative data. This provocative volume will be read with interest by researchers and students in qualitative research methods, ethnography, education, sociology, and anthropology. "After defining metaphor and synthesis, these authors provide a step-by-step program that will allow the researcher to show similarity (reciprocal translation), difference (refutation), or similarity at a higher level (lines or argument synthesis) among sample studies....Contain(s) valuable strategies at a seldom-used level of analysis." --Contemporary Sociology "The authors made an important contribution by reframing how we think of ethnography comparison in a way that is compatible with the new developments in interpretive ethnography. Meta-Ethnography is well worth consulting for the problem definition it offers." --The Journal of Nervous and Mental Disease "This book had to be written and I am pleased it was. Someone needed to break the ice and offer a strategy for summarizing multiple ethnographic studies. Noblit and Hare have done a commendable job of giving the research community one approach for doing so. Further, no one else can now venture into this area of synthesizing qualitative studies without making references to and positioning themselves vis-a-vis this volume." -Educational Studies

Assembling the Pieces of a Systematic Review

Author : Margaret J. Foster
Publisher : Rowman & Littlefield
ISBN 13 : 1442277025
Total Pages : 243 pages
Book Rating : 4.4/5 (422 download)

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Book Synopsis Assembling the Pieces of a Systematic Review by : Margaret J. Foster

Download or read book Assembling the Pieces of a Systematic Review written by Margaret J. Foster and published by Rowman & Littlefield. This book was released on 2017-03-03 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a complete guide for librarians seeking to launch or refine their systematic review services. Conducting searches for systematic reviews goes beyond expert searching and requires an understanding of the entire process of the systematic review. Just as expert searching is not fully mastered by the end of a library degree, mastering the systematic review process takes a great deal of time and practice. Attending workshops and webinars can introduce the topic, but application of the knowledge through practice is required. Running a systematic review service is complicated and requires constant updating and evaluation with new standards, more efficient methods, and improved reporting guidelines. After a brief introduction to systematic reviews, the book guides librarians in defining and marketing their services, covering topics such as when it is appropriate to ask for co-authorship and how to reach out to stakeholders. Next, it addresses developing documentation and conducting the reference interview. Standards specific to systematic reviews, including PRISMA, Institute of Medicine, and Cochrane Collaboration, are discussed. Search strategy techniques, including choosing databases, harvesting search terms, selecting filters, and searching for grey literature are detailed. Data management and critical appraisal are covered in detail. Finally, the best practices for reporting the findings of systematic reviews are highlighted. Experts with experience in both systematic reviews and librarianship, including the editors of the book, contributed to the chapters. Each step (or piece) of the review process (Planning the review, Identifying the studies, Evaluating studies, Collecting and combining data, Explaining the results, and Summarizing the review into a report), are covered with emphasis on information roles. The book is for any librarian interested in conducting reviews or assisting others with reviews. It has several applications: for training librarians new to systematic reviews, for those developing a new systematic review service, for those wanting to establish protocols for a current service, and as a reference for those conducting reviews or running a service. Participating in systematic reviews is a new frontier of librarianship, in which librarians can truly become research partners with our patrons, instead of merely providing access to resources and services.

Systematic Reviews of Research in Basic Education in South Africa

Author : Felix Maringe
Publisher : African Sun Media
ISBN 13 : 1991201141
Total Pages : 292 pages
Book Rating : 4.9/5 (912 download)

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Book Synopsis Systematic Reviews of Research in Basic Education in South Africa by : Felix Maringe

Download or read book Systematic Reviews of Research in Basic Education in South Africa written by Felix Maringe and published by African Sun Media. This book was released on 2021-04-09 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maringe ought to be commended for putting together an invaluable contribution to our understanding of research into a complex education system in South Africa. This volume provides a useful foundation to the current state of education quality in South Africa including the impact of interventions. It also brings to the fore challenges still facing education transformation. The evidence presented which, taken together, lays out a coherent view of how improvements could be made. Albert Chanee Head of Planning, Gauteng Department of Education For too long the weight of educational scholarship produced in South Africa has been limited to that simple and standard form called the literature review. Now, for the first time, education researchers are provided with an African-based text on the concepts and methods of conducting systematic reviews. In this exceptional work of editorship, Felix Maringe brings together some of the leading researchers on South African education to model and demonstrate how to review a significant body of research on a chosen topic which is adjudicated strictly on the basis of the quality and efficacy of the evidence in hand. I have no doubt that this remarkable book will become a standard reference for educational researchers in and beyond the African continent. It will also lift the quality of educational inquiry by equipping a new generation of scholars with the capacity for doing evidence-based research that compels the attention of policymakers, planners and practitioners alike. Prof Jonathan Jansen Stellenbosch University

How to Practice Academic Medicine and Publish from Developing Countries?

Author : Samiran Nundy
Publisher : Springer Nature
ISBN 13 : 9811652481
Total Pages : 475 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis How to Practice Academic Medicine and Publish from Developing Countries? by : Samiran Nundy

Download or read book How to Practice Academic Medicine and Publish from Developing Countries? written by Samiran Nundy and published by Springer Nature. This book was released on 2021-10-23 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.

Systematic Reviews in Health Research

Author : Matthias Egger
Publisher : John Wiley & Sons
ISBN 13 : 1405160500
Total Pages : 612 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Systematic Reviews in Health Research by : Matthias Egger

Download or read book Systematic Reviews in Health Research written by Matthias Egger and published by John Wiley & Sons. This book was released on 2022-06-21 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org) A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.

The SAGE Encyclopedia of Qualitative Research Methods

Author : Lisa M. Given
Publisher : SAGE Publications
ISBN 13 : 1452265895
Total Pages : 1073 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis The SAGE Encyclopedia of Qualitative Research Methods by : Lisa M. Given

Download or read book The SAGE Encyclopedia of Qualitative Research Methods written by Lisa M. Given and published by SAGE Publications. This book was released on 2008-08-19 with total page 1073 pages. Available in PDF, EPUB and Kindle. Book excerpt: Qualitative research is designed to explore the human elements of a given topic, while specific qualitative methods examine how individuals see and experience the world. Qualitative approaches are typically used to explore new phenomena and to capture individuals′ thoughts, feelings, or interpretations of meaning and process. Such methods are central to research conducted in education, nursing, sociology, anthropology, information studies, and other disciplines in the humanities, social sciences, and health sciences. Qualitative research projects are informed by a wide range of methodologies and theoretical frameworks. The SAGE Encyclopedia of Qualitative Research Methods presents current and complete information as well as ready-to-use techniques, facts, and examples from the field of qualitative research in a very accessible style. In taking an interdisciplinary approach, these two volumes target a broad audience and fill a gap in the existing reference literature for a general guide to the core concepts that inform qualitative research practices. The entries cover every major facet of qualitative methods, including access to research participants, data coding, research ethics, the role of theory in qualitative research, and much more—all without overwhelming the informed reader. Key Features Defines and explains core concepts, describes the techniques involved in the implementation of qualitative methods, and presents an overview of qualitative approaches to research Offers many entries that point to substantive debates among qualitative researchers regarding how concepts are labeled and the implications of such labels for how qualitative research is valued Guides readers through the complex landscape of the language of qualitative inquiry Includes contributors from various countries and disciplines that reflect a diverse spectrum of research approaches from more traditional, positivist approaches, through postmodern, constructionist ones Presents some entries written in first-person voice and others in third-person voice to reflect the diversity of approaches that define qualitative work Key Themes Approaches and Methodologies Arts-Based Research, Ties to Computer Software Data Analysis Data Collection Data Types and Characteristics Dissemination History of Qualitative Research Participants Quantitative Research, Ties to Research Ethics Rigor Textual Analysis, Ties to Theoretical and Philosophical Frameworks The SAGE Encyclopedia of Qualitative Research Methods is designed to appeal to undergraduate and graduate students, practitioners, researchers, consultants, and consumers of information across the social sciences, humanities, and health sciences, making it a welcome addition to any academic or public library.

Using Mixed Methods Research Synthesis for Literature Reviews

Author : Mieke Heyvaert
Publisher : SAGE Publications
ISBN 13 : 1483358305
Total Pages : 170 pages
Book Rating : 4.4/5 (833 download)

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Book Synopsis Using Mixed Methods Research Synthesis for Literature Reviews by : Mieke Heyvaert

Download or read book Using Mixed Methods Research Synthesis for Literature Reviews written by Mieke Heyvaert and published by SAGE Publications. This book was released on 2016-03-03 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide provides step-by-step instruction for conducting a mixed methods research synthesis (MMRS) that integrates both qualitative and quantitative evidence. The book progresses through a systematic, comprehensive approach to conducting an MMRS literature review to analyze and summarize the empirical evidence regarding a particular review question. Readers will benefit from discussion of the potential advantages of MMRS and guidance on how to avoid its potential pitfalls. Using Mixed Methods Research Synthesis for Literature Reviews is Volume 4 in the SAGE Mixed Methods Research Series.

The SAGE Encyclopedia of Communication Research Methods

Author : Mike Allen
Publisher : SAGE Publications
ISBN 13 : 1483381420
Total Pages : 2013 pages
Book Rating : 4.4/5 (833 download)

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Book Synopsis The SAGE Encyclopedia of Communication Research Methods by : Mike Allen

Download or read book The SAGE Encyclopedia of Communication Research Methods written by Mike Allen and published by SAGE Publications. This book was released on 2017-04-11 with total page 2013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Communication research is evolving and changing in a world of online journals, open-access, and new ways of obtaining data and conducting experiments via the Internet. Although there are generic encyclopedias describing basic social science research methodologies in general, until now there has been no comprehensive A-to-Z reference work exploring methods specific to communication and media studies. Our entries, authored by key figures in the field, focus on special considerations when applied specifically to communication research, accompanied by engaging examples from the literature of communication, journalism, and media studies. Entries cover every step of the research process, from the creative development of research topics and questions to literature reviews, selection of best methods (whether quantitative, qualitative, or mixed) for analyzing research results and publishing research findings, whether in traditional media or via new media outlets. In addition to expected entries covering the basics of theories and methods traditionally used in communication research, other entries discuss important trends influencing the future of that research, including contemporary practical issues students will face in communication professions, the influences of globalization on research, use of new recording technologies in fieldwork, and the challenges and opportunities related to studying online multi-media environments. Email, texting, cellphone video, and blogging are shown not only as topics of research but also as means of collecting and analyzing data. Still other entries delve into considerations of accountability, copyright, confidentiality, data ownership and security, privacy, and other aspects of conducting an ethical research program. Features: 652 signed entries are contained in an authoritative work spanning four volumes available in choice of electronic or print formats. Although organized A-to-Z, front matter includes a Reader’s Guide grouping entries thematically to help students interested in a specific aspect of communication research to more easily locate directly related entries. Back matter includes a Chronology of the development of the field of communication research; a Resource Guide to classic books, journals, and associations; a Glossary introducing the terminology of the field; and a detailed Index. Entries conclude with References/Further Readings and Cross-References to related entries to guide students further in their research journeys. The Index, Reader’s Guide themes, and Cross-References combine to provide robust search-and-browse in the e-version.

Systematic Reviews in the Social Sciences

Author : Mark Petticrew
Publisher : John Wiley & Sons
ISBN 13 : 1405150149
Total Pages : 352 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Systematic Reviews in the Social Sciences by : Mark Petticrew

Download or read book Systematic Reviews in the Social Sciences written by Mark Petticrew and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all social science disciplines; It requires no previous knowledge, but takes the reader through the process stage by stage; Drawing on examples from such diverse fields as psychology, criminology, education, transport, social welfare, public health, and housing and urban policy, among others. Including detailed sections on assessing the quality of both quantitative, and qualitative research; searching for evidence in the social sciences; meta-analytic and other methods of evidence synthesis; publication bias; heterogeneity; and approaches to dissemination.