Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles

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Publisher : Springer Science & Business Media
ISBN 13 : 3642730205
Total Pages : 221 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles by : Max L. Birnstiel

Download or read book Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles written by Max L. Birnstiel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade a most interesting story of the role played by the small nuclear RNPs, catalysts in RNA processing, has unfolded. Early investigations of the structure of these particles gave rise to hypotheses of their functions. As described in this book, these have been confirmed or are being tested by biochemical ex perimentation and most recently by the powerful technique of genetic analysis. Both biochemical and genetical approaches will also determine to what degree, and how, snRNPs and their cofactors participate in the differential expression of genes. As the details emerge and the number of snRNP species increases way beyond the six initially identified, one feels at the threshold of even greater things to come. The book covers many results in one of the most rapidly expanding fields of molecular biology. For this reason alone the specialist may detect some omissions and shortcomings. I hope they will be few. Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field. While not each and every snRNP story can be covered in such a book, I hope that it will provide enjoyable and stimulating reading.

Small Nuclear Ribonucleoprotein Particles

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Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.:/5 (77 download)

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Book Synopsis Small Nuclear Ribonucleoprotein Particles by : Eugenia A. Saba

Download or read book Small Nuclear Ribonucleoprotein Particles written by Eugenia A. Saba and published by . This book was released on 1991 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Nucleolus

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306478734
Total Pages : 370 pages
Book Rating : 4.4/5 (787 download)

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Book Synopsis The Nucleolus by : Mark O. J. Olson

Download or read book The Nucleolus written by Mark O. J. Olson and published by Springer Science & Business Media. This book was released on 2004-08-03 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged in research on the nucleolus and have an in depth review of the following topics: - nucleolar ultrastructure and dynamics, - behavior during mitosis, - ribosomal DNA gene and chromatin structure, - pre-ribosomal RNA transcription, - processing and modification, - ribosome assembly, - small nucleolar RNAs, - proteomics and non-traditional functions of the nucleolus. Separate chapters are also provided for yeast and higher eukaryotes on many topics. The Nucleolus will appeal not only to scientists directly engaged in nucleolar research, but also those working in related areas such as gene expression, protein biosynthesis, ribosome structure, transcription, chromatin structure, molecular genetics and the structure and functions of the cell nucleus in general.

Nuclear Particles

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Publisher : Academic Press
ISBN 13 : 1483216802
Total Pages : 424 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Nuclear Particles by : Harris Busch

Download or read book Nuclear Particles written by Harris Busch and published by Academic Press. This book was released on 2013-10-22 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cell Nucleus, Volume III: Nuclear Particles, Part A covers topics on "splicing" and "processing" and on the controls of transcriptional and transport events that must be essential to cells that are either growing and/or are phenotypically differentiated. The book discusses the immunolocalization and structural organization of nascent RNP; the in situ localization of RNA structures; and the morphogenesis, cytochemistry, and putative role of perichromatin granules. The text describes transcription in the isolated nuclei; the isolation and structure of the ribonucleoprotein fibrils containing heterogeneous nuclear RNA; and low-molecular-weight nuclear ribonucleoprotein particles. The sequence, function, and role of U snRNAs of nuclear snRNPs; the maturation of low-molecular-weight RNA species; and the properties of the heterogeneous nuclear RNA-protein complexes and nuclear matrix are also encompassed. The book further tackles human antibodies to RNA-containing particles. Cellular biologists, microbiologists, pharmacologists, geneticists, and students taking related courses will find the book useful.

Nuclear Structure and Function

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Publisher : Academic Press
ISBN 13 : 0125641559
Total Pages : 659 pages
Book Rating : 4.1/5 (256 download)

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Book Synopsis Nuclear Structure and Function by : Miguel Berrios

Download or read book Nuclear Structure and Function written by Miguel Berrios and published by Academic Press. This book was released on 1998 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes. Key Features * Provides a practical laboratory guide for studying cell nuclei * Includes comprehensive and easy-to-follow protocols

Structure of Antigens

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Publisher : CRC Press
ISBN 13 : 9780849388675
Total Pages : 404 pages
Book Rating : 4.3/5 (886 download)

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Book Synopsis Structure of Antigens by : Marc H. V. Van Regenmortel

Download or read book Structure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1992-12-07 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II

The Eukaryotic Nucleus

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Publisher : CRC Press
ISBN 13 : 9780936923338
Total Pages : 476 pages
Book Rating : 4.9/5 (233 download)

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Book Synopsis The Eukaryotic Nucleus by : Samuel H. Wilson

Download or read book The Eukaryotic Nucleus written by Samuel H. Wilson and published by CRC Press. This book was released on 1990-08-09 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series provides, in two volumes, a complete and exhaustive review of the subject of the eukaryotic nucleus, the site of the DNA. The focus of the book is how the information in the DNA is transcribed, accessed and maintained.

Alternative Splicing and Cancer

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Publisher : CRC Press
ISBN 13 : 1040030688
Total Pages : 264 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Alternative Splicing and Cancer by : Muzafar A. Macha

Download or read book Alternative Splicing and Cancer written by Muzafar A. Macha and published by CRC Press. This book was released on 2024-05-03 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer. Diving deep into the complexities of gene expression and protein diversity, the book illuminates how abnormal splicing contributes to aggressive tumor formation, affecting cellular functions such as proliferation, survival, and immune evasion. With a focus on understanding molecular mechanisms, this book unravels potential diagnostic and prognostic targets, opening doors for enhanced anti-cancer treatment efficacy. An indispensable resource for anyone intrigued by the interplay between gene splicing and cancer biology, it paves the way towards innovative therapeutic strategies.

Progress in Molecular and Subcellular Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642751784
Total Pages : 195 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Progress in Molecular and Subcellular Biology by : Philippe Jeanteur

Download or read book Progress in Molecular and Subcellular Biology written by Philippe Jeanteur and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and the cell/plasma membranes. It is the aim of this series to discuss actual aspects in the field of structure-associated genetic and epigenetic functional processes. This series of survey reviews fills the gap in structure-associated information flow, and is a vital reference work for scientists in molecular and cell biology.

Progress in Nucleic Acid Research and Molecular Biology

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Publisher : Academic Press
ISBN 13 : 0080863388
Total Pages : 359 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Progress in Nucleic Acid Research and Molecular Biology by :

Download or read book Progress in Nucleic Acid Research and Molecular Biology written by and published by Academic Press. This book was released on 1995-05-25 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM THE REVIEWS OF THE PREVIOUS VOLUMES: "In perusing these chapters, I found much of interest. It is worth investigating." - P. Bricknell in BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." -BRITISH MEDICAL JOURNAL. * * Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology * Contributions from leaders in their fields * Abundant references

Genetic Engineering

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Publisher : Springer Science & Business Media
ISBN 13 : 1461306418
Total Pages : 346 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Genetic Engineering by : Jane K. Setlow

Download or read book Genetic Engineering written by Jane K. Setlow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sixteen contributions cover such topics as the polymerase chain reaction; regulation of alternative splicing; human retinoblastoma susceptibility gene; control of translation initiation in mammalian cells; the utility of streptomycetes as hosts for gene cloning; folding of eukaryotic proteins produc

RNA Trafficking and Nuclear Structure Dynamics

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Publisher : Springer
ISBN 13 : 3540742662
Total Pages : 161 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis RNA Trafficking and Nuclear Structure Dynamics by : Philippe Jeanteur

Download or read book RNA Trafficking and Nuclear Structure Dynamics written by Philippe Jeanteur and published by Springer. This book was released on 2007-11-03 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.

Membrane Protein Transport

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Publisher : Elsevier
ISBN 13 : 008053614X
Total Pages : 281 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Membrane Protein Transport by : S.S. Rothman

Download or read book Membrane Protein Transport written by S.S. Rothman and published by Elsevier. This book was released on 1996-04-16 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume in a series on membrane protein transfer. Membrane protein transport underlies the topological disposition of many proteins within cells and it is this disposition that allows for the co-ordination of the central cellular processes, such as metabolism.

Eukaryotic Nucleus

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Publisher : CRC Press
ISBN 13 : 9780936923406
Total Pages : 88 pages
Book Rating : 4.9/5 (234 download)

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Book Synopsis Eukaryotic Nucleus by : Samuel H. Wilson

Download or read book Eukaryotic Nucleus written by Samuel H. Wilson and published by CRC Press. This book was released on 1990-08-31 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nuclear Structure and Gene Expression

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Publisher : Elsevier
ISBN 13 : 0080537812
Total Pages : 317 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Nuclear Structure and Gene Expression by : R. Curtis Bird

Download or read book Nuclear Structure and Gene Expression written by R. Curtis Bird and published by Elsevier. This book was released on 1996-11-28 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology.* Mechanisms of interaction between nuclear structure and genes* Gene expression regulation by elements of the nuclear matrix* How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology

Manual of Biological Markers of Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9401116709
Total Pages : 711 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Manual of Biological Markers of Disease by : W.J. van Venrooij

Download or read book Manual of Biological Markers of Disease written by W.J. van Venrooij and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference work: This looseleaf work is an authoritative compilation of methods for the detection of autoantibodies (Section A: Methods of Autoantibody Detection); the structure, function, and molecular and biochemical concepts of autoantigens (Section B: Autoantigens); and the clinical significance of measuring autoantibodies in patients with rheumatic, connective tissue and autoimmune diseases (Section C: Clinical Significance of Autoantibodies). This unique work brings together all the molecular and medical information - very difficult to retrieve otherwise - in ONE publication. The Editors and contributors are leading experts in the immunological, molecular biological, and clinical fields. The format of this looseleaf publication allows regular updating of data as well as inclusion of new advances in research on autoimmunity. Until now, the work (Basic work including Supplement 1) included Section A, and the larger part of Section B, both in an attractive and robust ringbinder. Audience: By nature and design of this exciting reference work, it is especially aimed at scientists, including immunologists, pathologists and molecular biologists, and clinical chemists, as well as clinicians specializing in rheumatic diseases and autoimmune disorders, inflammation or clinical immunology. Supplement 2: This supplement primarily contains Section C (Clinical Significance of Autoantibodies). As in the other sections, the contents are presented in a consistently structured manner, beautifully illustrated with photos and schematic figures. Extensive literature references are provided. Also, this supplement includes an addition to Section B (Autoantigens), being chapter B.1.5: The Antigens Defined by Antikeratin Antibodies (AKA).

Investigation of Free U6 Small Nuclear Ribonucleoprotein Structure and Function

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Investigation of Free U6 Small Nuclear Ribonucleoprotein Structure and Function by : Elizabeth Arlene Dunn

Download or read book Investigation of Free U6 Small Nuclear Ribonucleoprotein Structure and Function written by Elizabeth Arlene Dunn and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: