Structural Studies On Compounds Of Biological Significance With Emphasis On Mass Spectrometry

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Proteomic and Metabolomic Approaches to Biomarker Discovery

Author : Haleem J. Issaq
Publisher : Academic Press
ISBN 13 : 0123947952
Total Pages : 489 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Proteomic and Metabolomic Approaches to Biomarker Discovery by : Haleem J. Issaq

Download or read book Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq and published by Academic Press. This book was released on 2013-05-20 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. - Describes the use of biomarkers to reduce clinical errors in research - Includes techniques from a range of biomarker discoveries - Covers all steps involved in biomarker discovery, from study design to study execution

Opportunities in Biology

Author : National Research Council
Publisher : National Academies
ISBN 13 : 0309039274
Total Pages : 471 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Opportunities in Biology by : National Research Council

Download or read book Opportunities in Biology written by National Research Council and published by National Academies. This book was released on 1989-01-01 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.

Beyond the Molecular Frontier

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Mass Spectrometry

Author : A.L. Burlingame
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121828073
Total Pages : 520 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Biological Mass Spectrometry by : A.L. Burlingame

Download or read book Biological Mass Spectrometry written by A.L. Burlingame and published by Gulf Professional Publishing. This book was released on 2005-11-28 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes and integrates the techniques of many advances in both chromatographic and mass spectrometric technologies. This book also covers various biophysical applications, such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. It also describes atto-to-zepto-mole quantitation of 14C and 3H.

Differential Ion Mobility Spectrometry

Author : Alexandre A. Shvartsburg
Publisher : CRC Press
ISBN 13 : 9781420051070
Total Pages : 322 pages
Book Rating : 4.0/5 (51 download)

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Book Synopsis Differential Ion Mobility Spectrometry by : Alexandre A. Shvartsburg

Download or read book Differential Ion Mobility Spectrometry written by Alexandre A. Shvartsburg and published by CRC Press. This book was released on 2008-12-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, scientific and engineering interests have been shifting from conventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry: Nonlinear Ion Transport and Fundamentals of FAIMS explores this new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of dipole direction. The book relates the fundamentals of FAIMS and other nonlinear IMS methods to the physics of gas-phase ion transport. It begins with the basics of ion diffusion and mobility in gases, covering the main attributes of conventional IMS that are relevant to all IMS approaches. Building on this foundation, the author reviews diverse high-field transport phenomena that underlie differential IMS. He discusses the conceptual implementation and first-principles optimization of FAIMS as a filtering technique, emphasizing the dependence of FAIMS performance metrics on instrumental parameters and properties of ion species. He also explores ion reactions in FAIMS caused by field heating and the effects of inhomogeneous electric field in curved FAIMS gaps. Written by an accomplished scientist in the field, this state-of-the-art book supplies the foundation to understand the new technology of nonlinear IMS methods.

Chemistry of Protein Conjugation and Cross-Linking

Author : Shan S. Wong
Publisher : CRC Press
ISBN 13 : 9780849358869
Total Pages : 360 pages
Book Rating : 4.3/5 (588 download)

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Book Synopsis Chemistry of Protein Conjugation and Cross-Linking by : Shan S. Wong

Download or read book Chemistry of Protein Conjugation and Cross-Linking written by Shan S. Wong and published by CRC Press. This book was released on 1991-06-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.

Mass Spectrometry for the Clinical Laboratory

Author : Hari Nair
Publisher : Academic Press
ISBN 13 : 0128009926
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mass Spectrometry for the Clinical Laboratory by : Hari Nair

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Introduction to Bioorganic Chemistry and Chemical Biology

Author : David Van Vranken
Publisher : Garland Science
ISBN 13 : 1135054827
Total Pages : 571 pages
Book Rating : 4.1/5 (35 download)

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Book Synopsis Introduction to Bioorganic Chemistry and Chemical Biology by : David Van Vranken

Download or read book Introduction to Bioorganic Chemistry and Chemical Biology written by David Van Vranken and published by Garland Science. This book was released on 2018-10-08 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science. Please note that Garland Science flashcards are no longer available for this text. However, the solutions can be obtained through our Support Material Hub link below, but should only be requested by instructors who have adopted the book on their course.

Neuroproteomics

Author : Oscar Alzate
Publisher : CRC Press
ISBN 13 : 1420076264
Total Pages : 356 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neuroproteomics by : Oscar Alzate

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Advancements of Mass Spectrometry in Biomedical Research

Author : Alisa G. Woods
Publisher : Springer
ISBN 13 : 3319060686
Total Pages : 601 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Advancements of Mass Spectrometry in Biomedical Research by : Alisa G. Woods

Download or read book Advancements of Mass Spectrometry in Biomedical Research written by Alisa G. Woods and published by Springer. This book was released on 2014-06-20 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Research Grants Index

Author : National Institutes of Health (U.S.). Division of Research Grants
Publisher :
ISBN 13 :
Total Pages : 1224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles and Applications of Clinical Mass Spectrometry

Author : Nader Rifai
Publisher : Elsevier
ISBN 13 : 0128160640
Total Pages : 218 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai

Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. - Provides concrete examples of the main applications of mass spectrometry technology - Describes current capabilities of the LC- and MS-based analytical methods - Details methods for successful analytical work in the field

Research Awards Index

Author :
Publisher :
ISBN 13 :
Total Pages : 852 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1987 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Author :
Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biomedical Index to PHS-supported Research: pt. A. Subject access A-H by :

Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences

Author : National Institute of General Medical Sciences (U.S.)
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences by : National Institute of General Medical Sciences (U.S.)

Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences written by National Institute of General Medical Sciences (U.S.) and published by . This book was released on 1975 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences

Author : National Institute of General Medical Sciences (U.S.). Division of Research Grants
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences by : National Institute of General Medical Sciences (U.S.). Division of Research Grants

Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Institute of General Medical Sciences written by National Institute of General Medical Sciences (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: