Use of Laboratory Animals in Biomedical and Behavioral Research

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Author :
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Statistics of scientific procedures on living animals

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Author :
Publisher : The Stationery Office
ISBN 13 : 9780101629126
Total Pages : 104 pages
Book Rating : 4.6/5 (291 download)

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Book Synopsis Statistics of scientific procedures on living animals by : Great Britain. Home Office

Download or read book Statistics of scientific procedures on living animals written by Great Britain. Home Office and published by The Stationery Office. This book was released on 2004 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This annual publication contains data on animal experimentation carried out during 2003, subject to the provisions of the Animals (Scientific Procedures) Act 1986. Under this Act, any scientific procedure carried out on any living vertebrate animal, and one species of octopus, which is likely to cause pain, suffering, distress or lasting harm is a regulated procedure requiring licence authority. The data is structured to comply with EU requirements, although it is far more extensive than required by Europe. In 2003, there were 2.79 million scientific procedures conducted, an increase of 2.2 per cent on the previous year. Most experiments and tests were conducted on mice, rats and other rodents (85 per cent), with the remainder on birds (four per cent) and fish (six per cent). Dogs, cats, horses and non-human primates (usually macaques and marmosets) combined amounted to less than one per cent of procedures. Genetically modified animals were used in 27 per cent of cases, an increase of one per cent on 2002 and 19 per cent on 1995). Non-toxicological procedures accounted for 84 per cent of procedures, with the main areas of use being for immunological studies, pharmaceutical research and development, and cancer research.

The Principles of Humane Experimental Technique

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Author :
Publisher : Hyperion Books
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis The Principles of Humane Experimental Technique by : William Moy Stratton Russell

Download or read book The Principles of Humane Experimental Technique written by William Moy Stratton Russell and published by Hyperion Books. This book was released on 1992 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Laboratory Animal Welfare

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Publisher : Academic Press
ISBN 13 : 0123851041
Total Pages : 335 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Laboratory Animal Welfare by : Kathryn Bayne

Download or read book Laboratory Animal Welfare written by Kathryn Bayne and published by Academic Press. This book was released on 2013-09-02 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.

Animal Experimentation

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Publisher :
ISBN 13 : 9789004356184
Total Pages : 0 pages
Book Rating : 4.3/5 (561 download)

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Book Synopsis Animal Experimentation by : Kathrin Herrmann

Download or read book Animal Experimentation written by Kathrin Herrmann and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

International Animal Research Regulations

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Publisher : National Academies Press
ISBN 13 : 0309252113
Total Pages : 102 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis International Animal Research Regulations by : National Research Council

Download or read book International Animal Research Regulations written by National Research Council and published by National Academies Press. This book was released on 2012-06-26 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.

Science, Medicine, and Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309101174
Total Pages : 23 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science, Medicine, and Animals by : National Research Council

Download or read book Science, Medicine, and Animals written by National Research Council and published by National Academies Press. This book was released on 2006-02-19 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association NSTA Recommends.

Guidance for the Description of Animal Research in Scientific Publications

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Publisher : National Academies Press
ISBN 13 : 030921954X
Total Pages : 42 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Guidance for the Description of Animal Research in Scientific Publications by : National Research Council

Download or read book Guidance for the Description of Animal Research in Scientific Publications written by National Research Council and published by National Academies Press. This book was released on 2011-09-16 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move the science forward. Analyses of published studies with research animals have demonstrated numerous deficiencies in the reporting of details in research methods for animal studies. Considerable variation in the amount of information required by scientific publications and reported by authors undermines this basic scientific principle and results in the unnecessary use of animals and other resources in failed efforts to reproduce study results. Guidance for the Description of Animal Research in Scientific Publications outlines the information that should be included in scientific papers regarding the animal studies to ensure that the study can be replicated. The report urges journal editors to actively promote effective and ethical research by encouraging the provision of sufficient information. Examples of this information include: conditions of housing and husbandry, genetic nomenclature, microbial status, detailed experimental manipulations, and handling and use of pharmaceuticals. Inclusion of this information will enable assessment and interpretation of research findings and advancement of knowledge based on reproducible results.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

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Author :
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Animals (Scientific Procedures) Act 1986

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Publisher :
ISBN 13 : 9780105567066
Total Pages : 103 pages
Book Rating : 4.5/5 (67 download)

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Book Synopsis Animals (Scientific Procedures) Act 1986 by : Great Britain. Home Office

Download or read book Animals (Scientific Procedures) Act 1986 written by Great Britain. Home Office and published by . This book was released on 2000 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guidance on the Operation of the Animals (Scientific Procedures) ACT 1986

Improved Standards for Laboratory Animals Act; and Enforcement of the Animal Welfare Act by the Animal and Plant Health Inspection Service

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Author :
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Improved Standards for Laboratory Animals Act; and Enforcement of the Animal Welfare Act by the Animal and Plant Health Inspection Service by : United States. Congress. House. Committee on Agriculture. Subcommittee on Department Operations, Research, and Foreign Agriculture

Download or read book Improved Standards for Laboratory Animals Act; and Enforcement of the Animal Welfare Act by the Animal and Plant Health Inspection Service written by United States. Congress. House. Committee on Agriculture. Subcommittee on Department Operations, Research, and Foreign Agriculture and published by . This book was released on 1985 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Statistics of Scientific Procedures on Living Animals

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Publisher :
ISBN 13 : 9781474124997
Total Pages : 60 pages
Book Rating : 4.1/5 (249 download)

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Book Synopsis Annual Statistics of Scientific Procedures on Living Animals by : Great Britain: Home Office

Download or read book Annual Statistics of Scientific Procedures on Living Animals written by Great Britain: Home Office and published by . This book was released on 2015-10-22 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print and web pdfs are available at https://www.gov.uk/government/publications

Statistics for Veterinary and Animal Science

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Publisher : John Wiley & Sons
ISBN 13 : 1118567404
Total Pages : 425 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Statistics for Veterinary and Animal Science by : Aviva Petrie

Download or read book Statistics for Veterinary and Animal Science written by Aviva Petrie and published by John Wiley & Sons. This book was released on 2013-02-28 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Banish your fears of statistical analysis using this clearly written and highly successful textbook. Statistics for Veterinary and Animal Science Third Edition is an introductory text which assumes no previous knowledge of statistics. It starts with very basic methodology and builds on it to encompass some of the more advanced techniques that are currently used. This book will enable you to handle numerical data and critically appraise the veterinary and animal science literature. Written in a non-mathematical way, the emphasis is on understanding the underlying concepts and correctly interpreting computer output, and not on working through mathematical formulae. Key features: Flow charts are provided to enable you to choose the correct statistical analyses in different situations Numerous real worked examples are included to help you master the procedures Two statistical packages, SPSS and Stata, are used to analyse data to familiarise you with typical computer output The data sets from the examples in the book are available as electronic files to download from the book’s companion website in ASCII, Excel, SPSS, Stata and R Workspace formats, allowing you to practice using your own software and fully get to grips with the techniques A clear indication is provided of the more advanced or obscure topics so that, if desired, you can skip them without loss of continuity. New to this edition: New chapter on reporting guidelines relevant to veterinary medicine as a ready reference for those wanting to follow best practice in planning and writing up research New chapter on critical appraisal of randomized controlled trials and observational studies in the published literature: a template is provided which is used to critically appraise two papers New chapter introducing specialist topics: ethical issues of animal investigations, spatial statistics, veterinary surveillance, and statistics in molecular and quantitative genetics Expanded glossaries of notation and terms Additional exercises and further explanations added throughout to make the book more comprehensive. Carrying out statistical procedures and interpreting the results is an integral part of veterinary and animal science. This is the only book on statistics that is specifically written for veterinary science and animal science students, researchers and practitioners.

Science, Medicine, and Animals

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Author :
Publisher : National Academies Press
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science, Medicine, and Animals by : Committee on the Use of Animals in Research (U.S.)

Download or read book Science, Medicine, and Animals written by Committee on the Use of Animals in Research (U.S.) and published by National Academies Press. This book was released on 1991 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: The necessity for animal use in biomedical research is a hotly debated topic in classrooms throughout the country. Frequently teachers and students do not have access to balanced,  factual material to foster an informed discussion on the topic. This colorful, 50-page booklet is designed to educate teenagers about the role of animal research in combating disease, past and present; the perspective of animal use within the whole spectrum of biomedical research; the regulations and oversight that govern animal research; and the continuing efforts to use animals more efficiently and humanely.

In the Name of Science

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Publisher : Oxford University Press
ISBN 13 : 0199762805
Total Pages : 312 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis In the Name of Science by : F. Barbara Orlans

Download or read book In the Name of Science written by F. Barbara Orlans and published by Oxford University Press. This book was released on 1993-07-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few arguments in biomedical experimentation have stirred such heated debate in recent years as those raised by animal research. In this comprehensive analysis of the social, political, and ethical conflicts surrounding the use of animals in scientific experiments, Barbara Orlans judges both ends of the spectrum in this debate -- unconditional approval or rejection of animal experimentation -- to be untenable. Instead of arguing for either view, she thoughtfully explores the ground between the extremes, and convincingly makes the case for public policy reforms that serve to improve the welfare of laboratory animals without jeopardizing scientific endeavor. This book presents controversial issues in a balanced manner based on careful historical analysis and original research. Different mechanisms of oversight for animal experiments are compared and those that have worked well are identified. This compelling work will be of interest to biomedical scientists, ethicists, animal welfare advocates and other readers concerned with this critical issue.

Guidelines for the Humane Transportation of Research Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 030916477X
Total Pages : 164 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Humane Transportation of Research Animals by : National Research Council

Download or read book Guidelines for the Humane Transportation of Research Animals written by National Research Council and published by National Academies Press. This book was released on 2006-07-14 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transportation of agricultural animals, universal concepts of physiology, and a scientific understanding of species-specific needs and differences. Good practices were developed by the committee to address thermal environment, space requirements, food and water requirements, social interaction, monitoring of transportation, emergency procedures, personnel training, and biosecurity. Guidelines for the Humane Transportation of Research Animals is an essential guide for all researchers, animal care technicians, facilities managers, administrators, and animal care and use committees at research institutions.