Statistical Methods and Reasoning for the Clinical Sciences

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Publisher : Plural Publishing
ISBN 13 : 1597566578
Total Pages : 593 pages
Book Rating : 4.5/5 (975 download)

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Book Synopsis Statistical Methods and Reasoning for the Clinical Sciences by : Eiki Satake

Download or read book Statistical Methods and Reasoning for the Clinical Sciences written by Eiki Satake and published by Plural Publishing. This book was released on 2014-08-01 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Common Statistical Methods for Clinical Research with SAS Examples, Third Edition

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Author :
Publisher : SAS Institute
ISBN 13 : 1607644258
Total Pages : 553 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Common Statistical Methods for Clinical Research with SAS Examples, Third Edition by : Glenn Walker

Download or read book Common Statistical Methods for Clinical Research with SAS Examples, Third Edition written by Glenn Walker and published by SAS Institute. This book was released on 2010-02-15 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glenn Walker and Jack Shostak's Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is a thoroughly updated edition of the popular introductory statistics book for clinical researchers. This new edition has been extensively updated to include the use of ODS graphics in numerous examples as well as a new emphasis on PROC MIXED. Straightforward and easy to use as either a text or a reference, the book is full of practical examples from clinical research to illustrate both statistical and SAS methodology. Each example is worked out completely, step by step, from the raw data. Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is an applications book with minimal theory. Each section begins with an overview helpful to nonstatisticians and then drills down into details that will be valuable to statistical analysts and programmers. Further details, as well as bonus information and a guide to further reading, are presented in the extensive appendices. This text is a one-source guide for statisticians that documents the use of the tests used most often in clinical research, with assumptions, details, and some tricks--all in one place. This book is part of the SAS Press program.

Introduction to Statistical Methods for Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1584880279
Total Pages : 465 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Introduction to Statistical Methods for Clinical Trials by : Thomas D. Cook

Download or read book Introduction to Statistical Methods for Clinical Trials written by Thomas D. Cook and published by CRC Press. This book was released on 2007-11-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.

Introduction to Statistical Methods for Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1584880279
Total Pages : 465 pages
Book Rating : 4.5/5 (848 download)

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Book Synopsis Introduction to Statistical Methods for Clinical Trials by : Thomas D. Cook

Download or read book Introduction to Statistical Methods for Clinical Trials written by Thomas D. Cook and published by CRC Press. This book was released on 2007-11-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.

Medical Uses of Statistics

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Publisher : CRC Press
ISBN 13 : 0429529600
Total Pages : 490 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Medical Uses of Statistics by : John C. Bailar III

Download or read book Medical Uses of Statistics written by John C. Bailar III and published by CRC Press. This book was released on 2019-05-20 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.

Statistical Concepts and Applications in Clinical Medicine

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Publisher : CRC Press
ISBN 13 : 0203497414
Total Pages : 360 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Statistical Concepts and Applications in Clinical Medicine by : John Aitchison

Download or read book Statistical Concepts and Applications in Clinical Medicine written by John Aitchison and published by CRC Press. This book was released on 2004-10-28 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Concepts and Applications in Clinical Medicine presents a unique, problem-oriented approach to using statistical methods in clinical medical practice through each stage of the clinical process, including observation, diagnosis, and treatment. The authors present each consultative problem in its original form, then describe the process o

Essential Statistical Methods for Medical Statistics

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Publisher : Elsevier
ISBN 13 : 0444537384
Total Pages : 363 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Essential Statistical Methods for Medical Statistics by : J. Philip Miller

Download or read book Essential Statistical Methods for Medical Statistics written by J. Philip Miller and published by Elsevier. This book was released on 2010-11-08 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. Contributors are internationally renowned experts in their respective areas Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research Methods for assessing Biomarkers, analysis of competing risks Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs Structural equations modelling and longitudinal data analysis

Small Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Statistics in Medicine

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Publisher : Academic Press
ISBN 13 : 0128153296
Total Pages : 823 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Statistics in Medicine by : Robert H. Riffenburgh

Download or read book Statistics in Medicine written by Robert H. Riffenburgh and published by Academic Press. This book was released on 2020-07-03 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistics in Medicine, Fourth Edition, helps medical and biomedical investigators design and answer questions about analyzing and interpreting data and predicting the sample size required to achieve useful results. It makes medical statistics easy for the non-biostatistician by outlining common methods used in 90% of medical research. The text covers how to plan studies from conception to publication, what to do with data, and follows with step-by-step instructions for biostatistical methods from the simplest levels, to more sophisticated methods now used in medical articles. Examples from almost every medical specialty, and from dentistry, nursing, pharmacy and health care management are provided. This book does not require background knowledge of statistics or mathematics beyond high school algebra and provides abundant clinical examples and exercises to reinforce concepts. It is a valuable source for biomedical researchers, healthcare providers and anyone who conducts research or quality improvement projects. Expands and revises important topics, such as basic concepts behind descriptive statistics and testing, descriptive statistics in three dimensions, the relationship between statistical testing and confidence intervals, and more Presents an easy-to-follow format with medical examples, step-by-step methods and check-yourself exercises Explains statistics for users with little statistical and mathematical background Encompasses all research development stages, from conceiving a study, planning it in detail, carrying out the methods, putting obtained data in analyzable form, analyzing and interpreting the results, and publishing the study

Advances in Statistical Methods for the Health Sciences

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Publisher : Springer Science & Business Media
ISBN 13 : 081764542X
Total Pages : 540 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis Advances in Statistical Methods for the Health Sciences by : Jean-Louis Auget

Download or read book Advances in Statistical Methods for the Health Sciences written by Jean-Louis Auget and published by Springer Science & Business Media. This book was released on 2007-08-08 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methods have become an increasingly important and integral part of research in the health sciences. Many sophisticated methodologies have been developed for specific applications and problems. This self-contained comprehensive volume covers a wide range of topics pertaining to new statistical methods in the health sciences, including epidemiology, pharmacovigilance, quality of life, survival analysis, and genomics. The book will serve the health science community as well as practitioners, researchers, and graduate students in applied probability, statistics, and biostatistics.

Advanced Medical Statistics (2nd Edition)

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Publisher : World Scientific
ISBN 13 : 9814583324
Total Pages : 1472 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Advanced Medical Statistics (2nd Edition) by : Lu Ying

Download or read book Advanced Medical Statistics (2nd Edition) written by Lu Ying and published by World Scientific. This book was released on 2015-06-29 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have been tremendous advances in biostatistics and bioinformatics. The new edition tries to cover as many important emerging areas and reflect as much progress as possible. Many distinguished scholars, who greatly advanced their research areas in statistical methodology as well as practical applications, also have revised several chapters with relevant updates and written new ones from scratch.The new edition has been divided into four sections, including, Statistical Methods in Medicine and Epidemiology, Statistical Methods in Clinical Trials, Statistical Genetics, and General Methods. To reflect the rise of modern statistical genetics as one of the most fertile research areas since the publication of the first edition, the brand new section on Statistical Genetics includes entirely new chapters reflecting the state of the art in the field.Although tightly related, all the book chapters are self-contained and can be read independently. The book chapters intend to provide a convenient launch pad for readers interested in learning a specific topic, applying the related statistical methods in their scientific research and seeking the newest references for in-depth research.

Research in Communication Sciences and Disorders

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Publisher : Plural Publishing
ISBN 13 : 163550211X
Total Pages : 294 pages
Book Rating : 4.6/5 (355 download)

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Book Synopsis Research in Communication Sciences and Disorders by : Lauren K. Nelson

Download or read book Research in Communication Sciences and Disorders written by Lauren K. Nelson and published by Plural Publishing. This book was released on 2020-08-26 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in Communication Sciences and Disorders: Methods for Systematic Inquiry, Fourth Edition is a comprehensive yet comprehendible text meant for instructors and students of research methods in the field of communication sciences and disorders. This forward-thinking book reflects the movement toward evidence-based practice in speech-language pathology and audiology. The authors ensure that the concepts associated with evidence-based practice are integrated throughout the chapters. Rather than treating empirical research and searching for clinical evidence as separate topics, this text presents both as different applications of a process of scientific inquiry. The order of the chapters reflects the steps a researcher or clinician might complete when conducting an investigation. Also included are features that help students be more active in learning the material. Each chapter has a set of review questions or case scenarios that can be used as homework, as probe questions in class, or as a basis for group activities. In addition, the authors provide lists of supplemental readings from the research literature in the field. New to the Fourth Edition: * New author: Jaimie L. Gilbert for an enhanced audiology perspective * New chapter: Writing a Literature Review * Reorganized for better flow of information * Various new and updated references to reflect the current state of research * Additional illustrations and tables * Expanded material on critical appraisal Disclaimer: Please note that ancillary content (such as documents, audio, and video, etc.) may not be included as published in the original print version of this book.

Essentials of Laboratory Animal Science: Principles and Practices

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Publisher : Springer Nature
ISBN 13 : 981160987X
Total Pages : 797 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Essentials of Laboratory Animal Science: Principles and Practices by : P. Nagarajan

Download or read book Essentials of Laboratory Animal Science: Principles and Practices written by P. Nagarajan and published by Springer Nature. This book was released on 2021-07-23 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Clinical Data Analysis on a Pocket Calculator

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Publisher : Springer
ISBN 13 : 3319271040
Total Pages : 334 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Clinical Data Analysis on a Pocket Calculator by : Ton J. Cleophas

Download or read book Clinical Data Analysis on a Pocket Calculator written by Ton J. Cleophas and published by Springer. This book was released on 2016-01-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: In medical and health care the scientific method is little used, and statistical software programs are experienced as black box programs producing lots of p-values, but little answers to scientific questions. The pocket calculator analyses appears to be, particularly, appreciated, because they enable medical and health professionals and students for the first time to understand the scientific methods of statistical reasoning and hypothesis testing. So much so, that it can start something like a new dimension in their professional world. In addition, a number of statistical methods like power calculations and required sample size calculations can be performed more easily on a pocket calculator, than using a software program. Also, there are some specific advantages of the pocket calculator method. You better understand what you are doing. The pocket calculator works faster, because far less steps have to be taken, averages can be used. The current nonmathematical book is complementary to the nonmathematical "SPSS for Starters and 2nd Levelers" (Springer Heidelberg Germany 2015, from the same authors), and can very well be used as its daily companion.

Controversial Statistical Issues in Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1439849625
Total Pages : 598 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Controversial Statistical Issues in Clinical Trials by : Shein-Chung Chow

Download or read book Controversial Statistical Issues in Clinical Trials written by Shein-Chung Chow and published by CRC Press. This book was released on 2016-04-19 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectives of clinical trials can be better achieved. Controversial Statistical Issues in Clinical Trials cov

Quantitative Medical Data Analysis Using Mathematical Tools and Statistical Techniques

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Publisher :
ISBN 13 : 9814476234
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Quantitative Medical Data Analysis Using Mathematical Tools and Statistical Techniques by :

Download or read book Quantitative Medical Data Analysis Using Mathematical Tools and Statistical Techniques written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods and Applications of Statistics in the Life and Health Sciences

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Publisher : John Wiley & Sons
ISBN 13 : 0470405090
Total Pages : 1027 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Methods and Applications of Statistics in the Life and Health Sciences by : Narayanaswamy Balakrishnan

Download or read book Methods and Applications of Statistics in the Life and Health Sciences written by Narayanaswamy Balakrishnan and published by John Wiley & Sons. This book was released on 2009-12-02 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inspired by the Encyclopedia of Statistical Sciences, Second Edition, this volume outlines the statistical tools for successfully working with modern life and health sciences research Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics, including: Sequential methods in biomedical research Statistical measures of human quality of life Change-point methods in genetics Sample size determination for clinical trials Mixed-effects regression models for predicting pre-clinical disease Probabilistic and statistical models for conception Statistical methods are explored and applied to population growth, disease detection and treatment, genetic and genomic research, drug development, clinical trials, screening and prevention, and the assessment of rehabilitation, recovery, and quality of life. These topics are explored in contributions written by more than 100 leading academics, researchers, and practitioners who utilize various statistical practices, such as election bias, survival analysis, missing data techniques, and cluster analysis for handling the wide array of modern issues in the life and health sciences. With its combination of traditional methodology and newly developed research, Methods and Applications of Statistics in the Life and Health Sciences has everything students, academics, and researchers in the life and health sciences need to build and apply their knowledge of statistical methods and applications.