Structure of Antigens

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Publisher : CRC Press
ISBN 13 : 9780849388675
Total Pages : 404 pages
Book Rating : 4.3/5 (886 download)

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Book Synopsis Structure of Antigens by : Marc H. V. Van Regenmortel

Download or read book Structure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1992-12-07 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II

Sructure of Antigens

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Publisher : CRC Press
ISBN 13 : 9780849388651
Total Pages : 430 pages
Book Rating : 4.3/5 (886 download)

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Book Synopsis Sructure of Antigens by : Marc H. V. Van Regenmortel

Download or read book Sructure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1992-02-03 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME 1

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Structure and Function of Antibodies

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Author :
Publisher : MDPI
ISBN 13 : 3039438972
Total Pages : 440 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Structure and Function of Antibodies by : Roy Jefferis

Download or read book Structure and Function of Antibodies written by Roy Jefferis and published by MDPI. This book was released on 2021-02-05 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed description of all kinds of therapeutic antibodies including IgGs, IgAs, IgEs, and IgMs, bispecific antibodies, chimeric antigen receptor antibodies, and antibody fragments. Details about how each of these antibodies interact with their ligands, the immune system, and their targets are provided. Additionally, this book delves into the details of antibody, Fc, and variable chain structures, and how subtle changes in structure, charge, flexibility, post-translational modification, and the ability to bind to natural antibody ligands can result in a significant impact on antibody activity and functionality. Finally, the book explains the critical quality attributes of modern therapeutic antibodies and how to ensure that antibodies entering development have the best possible chance of success.

Blood Groups and Red Cell Antigens

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (225 download)

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Book Synopsis Blood Groups and Red Cell Antigens by : Laura Dean

Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structural Biology in Immunology

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Publisher : Academic Press
ISBN 13 : 0128033703
Total Pages : 192 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Structural Biology in Immunology by : Chaim Putterman

Download or read book Structural Biology in Immunology written by Chaim Putterman and published by Academic Press. This book was released on 2018-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship Features a collaborative editorial effort, involving clinical immunologists and structural biologists Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology Gives interested parties a bridge to learn about computer modeling and structure based design principles

Molecular Biology of The Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunodermatology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461572282
Total Pages : 735 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Immunodermatology by : Bijan Safai

Download or read book Immunodermatology written by Bijan Safai and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: By 1940, immunological mechanisms had been proved to have fundamental influ ences on a great number and variety of skin reactions, and skin diseases had brought to light a great number of fundamental immunological mechanisms that were basic to a wide range of different diseases, dermatological and nondermato logical. The preeminence of dermatological research in the advancement of immu nological knowledge should not astonish anyone. For the skin is not only the most easily accessible tissue for producing and studying immunological reactions, it is also the great organ of protection that meets the first onslaughts of inimical environmental forces and agents-potential enemies, both living and dead. And protection is in essence what immunology is all about. To get an idea of the long-established role that testing the skin and the study of its many reactions has played in advancing general immunology, one need recall only smallpox vaccination; tuberculin testing; testing with fungal extracts; skin testing in hay fever, asthma, and serum sickness; skin tests with toxins and toxoids; the patch test; the passive transfer of skin-adhering antibodies (reagins); skin sensitization by simple chemicals; and similar dermatological procedures that have exerted their influence on medical and scientific disciplines far beyond dermatology.

Biologic Markers in Immunotoxicology

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Publisher : National Academies Press
ISBN 13 : 0309043891
Total Pages : 225 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Biologic Markers in Immunotoxicology by : National Research Council

Download or read book Biologic Markers in Immunotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are environmental pollutants threatening the human immune system? Researchers are rapidly approaching definitive answers to this question, with the aid of biologic markersâ€"sophisticated assessment tools that could revolutionize detection and prevention of certain diseases. This volume, third in a series on biologic markers, focuses on the human immune system and its response to environmental toxicants. The authoring committee provides direction for continuing development of biologic markers, with strategies for applying markers to immunotoxicology in humans and recommended outlines for clinical and field studies. This comprehensive, up-to-date volume will be invaluable to specialists in toxicology and immunology and to biologists and investigators involved in the development of biologic markers.

The Antigens

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Publisher : Academic Press
ISBN 13 : 1483269892
Total Pages : 588 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Antigens by : Michael Sela

Download or read book The Antigens written by Michael Sela and published by Academic Press. This book was released on 2014-05-10 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Antigens, Volume I is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology, structure and function, their initiation of the immune response, and the nature of the products of this response. The nature of the reaction of antigens with antibodies and with sensitized cells is also explored. Comprised of seven chapters, this volume begins with a discussion on the antigenic functions of nucleic acids as well as their immunogenicity, hapten functions, and serologic reactions. The reader is then introduced to the immunochemistry and antigenic determinants of enzymes, along with the structure and phylogeny of immunoglobulins and immunoglobulin allotypes. The evolution of proteins and their structure and function is also considered, paying particular attention to evolution by the random fixation of selectively neutral alleles, the rates of protein evolution, gene duplication, and divergence or convergence. The final chapter is devoted to the chemistry and biology of immunoglobulin E as well as the regulation of formation of their antibodies. This book will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

Bacterial Lipopolysaccharides

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Publisher : Springer Science & Business Media
ISBN 13 : 3709107334
Total Pages : 440 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Bacterial Lipopolysaccharides by : Yuriy A. Knirel

Download or read book Bacterial Lipopolysaccharides written by Yuriy A. Knirel and published by Springer Science & Business Media. This book was released on 2011-07-13 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling.

Structure of Antigens

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Author :
Publisher : CRC-Press
ISBN 13 : 9780849388675
Total Pages : 400 pages
Book Rating : 4.3/5 (886 download)

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Book Synopsis Structure of Antigens by : Marc H. V. van Regenmortel

Download or read book Structure of Antigens written by Marc H. V. van Regenmortel and published by CRC-Press. This book was released on 1992-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II

Vaccine Safety Forum

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Publisher : National Academies Press
ISBN 13 : 0309538572
Total Pages : 71 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Vaccine Safety Forum by : Board on Health Promotion and Disease Prevention

Download or read book Vaccine Safety Forum written by Board on Health Promotion and Disease Prevention and published by National Academies Press. This book was released on 1997-07-24 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: On November 6, 1995, the Institute of Medicine's Vaccine Safety Forum convened a workshop on detecting and responding to adverse events following vaccination. Workshop speakers and participants discussed the difficulties in detecting adverse events, current adverse events detection and response methods and procedures, suggestions for improving the means of detecting and responding to adverse events following vaccination, and future areas of research. This document represents a summary of that workshop.

The Blood Group Antigen FactsBook

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Publisher : Academic Press
ISBN 13 : 0124158498
Total Pages : 758 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Blood Group Antigen FactsBook by : Marion E. Reid

Download or read book The Blood Group Antigen FactsBook written by Marion E. Reid and published by Academic Press. This book was released on 2012-11-07 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Blood Group Antigen FactsBook has been an essential resource in the hematology, transfusion and immunogenetics fields since its first publication in the late 1990s.The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 32 blood group systems. It blends scientific background and clinical applications and provides busy researchers and clinicians with at-a-glance information on over 330 blood group antigens, including history and information on terminology, expression, chromosomal assignment, carrier molecular description, functions, molecular bases of antigens and phenotypes, effect of enzymes/chemicals, clinical significance, disease associations and key references. Includes over 330 entries on blood group antigens in individual factsheetsOffers a logical and concise catalogue structure for each antigen in an improved interior design for quick reference. Written by 3 international experts from the field of immunohematology and transfusion medicine.

Structure and Function of Antibodies

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Structure and Function of Antibodies by : Leonard Eleazar Glynn

Download or read book Structure and Function of Antibodies written by Leonard Eleazar Glynn and published by John Wiley & Sons. This book was released on 1981 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bacterial Capsules

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Publisher : Springer Science & Business Media
ISBN 13 : 3642746942
Total Pages : 165 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Bacterial Capsules by : Klaus Jann

Download or read book Bacterial Capsules written by Klaus Jann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many bacteria, such as certain Neisseria and Haemophilus or Escherichia coli, are able to withstand the bactericidal activity of complement and phagocytes. This bacterial self protection is brought about by encapsulation. Bacterial capsules thus enable the pathogenic bacteria to survive in the host by counter action or evasion of the nonspecific host defense in the early pre immune phase of an infection. It is only in the late immune phase of the infection, when specific anticapsular antibodies are formed and enforce the host's defense system, that this protective action is overcome. Encapsulated bacteria are then killed and eliminated. Interestingly, some capsules can not or only inefficiently be handled by the immune system. The ensuing lack of antibody formation results in a prolonged susceptibility of the host to the pathogenic bacteria exhibiting such capsules. It was found that bacterial capsules consist of acidic poly saccharides. From this it followed that the role of the capsules in the interaction of encapsulated bacteria with the host may be due to the chemistry of the capsular polysaccharides. This led to intensive studies of capsular polysaccharides in many laboratories. Our increasing knowledge of the structural features of capsular polysaccharides prompted not only immuno chemical studies analyzing the interactions of these poly saccharide antigens and characterizing the epitopes, but also investigations into their biosynthesis. These studies were complemented and supported by genetic analyses. Today many interdisciplinary investigations of capsular polysaccharides are in progress.

The Antigens

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Publisher : Academic Press
ISBN 13 : 1483269558
Total Pages : 584 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Antigens by : Michael Sela

Download or read book The Antigens written by Michael Sela and published by Academic Press. This book was released on 2014-05-10 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Antigens, Volume II is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from protein antigens and blood group antigens to low molecular weight antigens and immunoglobulin A. The idiotypy of antibodies is also explored, along with the application of antibodies to the measurement of substances of physiological and pharmacological interest. Comprised of six chapters, this volume begins with a discussion on the molecular bases of antigenicity and immunogenicity of proteins, followed by a chapter dealing with blood group antigens. The immunologic effects of low molecular weight antigens are then considered, together with their elicitation of allergic reactions and their tolerance and specific inhibition of the immune response. The next chapter focuses on the use of antibodies to measure substances of physiological and pharmacological interest, with emphasis on the general principle of quantitative immunoassay. The book also analyzes the idiotypy of antibodies before concluding with a description of the antibody functions of immunoglobulin A. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.