Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances

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Publisher : IARC Monographs on the Evaluat
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC Monographs on the Evaluat. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Carcinogens and Anticarcinogens in the Human Diet

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Publisher : National Academies Press
ISBN 13 : 0309175712
Total Pages : 433 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Carcinogens and Anticarcinogens in the Human Diet by : National Research Council

Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-02-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

Biologic Markers in Urinary Toxicology

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Publisher : National Academies Press
ISBN 13 : 0309052289
Total Pages : 322 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Biologic Markers in Urinary Toxicology by : National Research Council

Download or read book Biologic Markers in Urinary Toxicology written by National Research Council and published by National Academies Press. This book was released on 1995-08-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991).

Chemical Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1617379956
Total Pages : 447 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis Chemical Carcinogenesis by : Trevor M. Penning

Download or read book Chemical Carcinogenesis written by Trevor M. Penning and published by Springer Science & Business Media. This book was released on 2011-03-03 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

Toxicological Profile for Toluene

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Publisher :
ISBN 13 :
Total Pages : 366 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Toxicological Profile for Toluene by :

Download or read book Toxicological Profile for Toluene written by and published by . This book was released on 2000 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Profile for Hexachlorobutadiene

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Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Hexachlorobutadiene by :

Download or read book Toxicological Profile for Hexachlorobutadiene written by and published by . This book was released on 1994 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis

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Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis by : Charles C. Capen

Download or read book Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis written by Charles C. Capen and published by . This book was released on 1999 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 1997, an expert group was convened to discuss available knowledge on the epidemiology, pathology and mechanisms related to certain tumors that are commonly seen in essays for carcinogenicity in rodents in order that their importance in human hazard evaluation might be assessed. The tumors of interest were urinary bladder carcinomas associated with urolithiasis, microcrystalluria and certain urinary precipitates; renal corticol tumors in male rats associated with alpha-2 urinary globulin nephropathy; and thyroid follicular cell tumors associated with imbalances in thyroid stimulating hormone. Included in the book are a series of individually authored papers on these various topics, as well as a Concensus Report including consideration of how such data may be used within the evalation process in the IARC Monographs on the Evaluation of Carcinogenic risks to Humans.

Mechanisms of Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Toxicological Profile for Isophorone

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Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Isophorone by :

Download or read book Toxicological Profile for Isophorone written by and published by . This book was released on 1989 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluoride in Drinking Water

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Publisher : National Academies Press
ISBN 13 : 030910128X
Total Pages : 531 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fluoride in Drinking Water by : National Research Council

Download or read book Fluoride in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2007-01-22 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.

Toxicological Profile for 1,2-dichloroethane

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Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Toxicological Profile for 1,2-dichloroethane by :

Download or read book Toxicological Profile for 1,2-dichloroethane written by and published by . This book was released on 1994 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Taking an Exposure History

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Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Taking an Exposure History by : Arthur L. Frank

Download or read book Taking an Exposure History written by Arthur L. Frank and published by . This book was released on 2001 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Some Drugs and Herbal Products

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (972 download)

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Book Synopsis Some Drugs and Herbal Products by :

Download or read book Some Drugs and Herbal Products written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.

Toxicological Profile for Nitrophenols

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Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Nitrophenols by :

Download or read book Toxicological Profile for Nitrophenols written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dinitrotoluenes (DNT).

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Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Dinitrotoluenes (DNT). by :

Download or read book Dinitrotoluenes (DNT). written by and published by . This book was released on 1985 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tattooed Skin and Health

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318027774
Total Pages : 270 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Tattooed Skin and Health by : J. Serup

Download or read book Tattooed Skin and Health written by J. Serup and published by Karger Medical and Scientific Publishers. This book was released on 2015-03-26 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: With about 10–20% of the adult population in Europe being tattooed, there is a strong demand for publications discussing the various issues related to tattooed skin and health. Until now, only a few scientific studies on tattooing have been published. This book discusses different aspects of the various medical risks associated with tattoos, such as allergic reactions from red tattoos, papulo-nodular reactions from black tattoos as well as technical and psycho-social complications, in addition to bacterial and viral infections. Further sections are dedicated to the composition of tattoo inks, and a case is made for the urgent introduction of national and international regulations. Distinguished authors, all specialists in their particular fields, have contributed to this publication which provides a comprehensive view of the health implications associated with tattooing. The book covers a broad range of topics that will be of interest to clinicians and nursing staff, toxicologists and regulators as well as laser surgeons who often face the challenge of having to remove tattoos, professional tattooists and producers of tattoo ink.