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Author : David W. M. Benzies
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (597 download)
Download or read book Some Aspects of the Synthesis and Reactions of Substituted Indoles written by David W. M. Benzies and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard Sundberg
Publisher : Elsevier
ISBN 13 : 0323147860
Total Pages : 505 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Chemistry of Indoles written by Richard Sundberg and published by Elsevier. This book was released on 2012-12-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 18: The Chemistry of Indoles discusses the chemistry of indole derivatives. This book explores the potent biological activity of several indole derivatives and explains the structure of indole alkaloids. Organized into 10 chapters, this monograph starts with an overview of the most important types of reactions of the indole ring on a mechanical basis. This text then proceeds to review the methods of synthesizing indoles and describes the oxidations and rearrangements of indole derivatives. Other chapters explore the special features of the synthesis and reactivity of hydroxyindoles, acylindoles, and aminoindoles. This book discusses as well the properties of carboxyl groups, which is substituted on the benzenoid ring of the indole nucleus that is typical of aromatic carboxylic acids. The final chapter deals with the certain classes of indoles that are found in nature. Chemists, researchers, and readers interested in the chemistry of indoles will find this book extremely useful.
Author : Samuel Wellington Jones
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (72 download)
Download or read book Synthesis and Pharmacological Properties of Some 2-substituted Indoles written by Samuel Wellington Jones and published by . This book was released on 1975 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kuldeep Singh
Publisher : Notion Press
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.8/5 (852 download)
Download or read book Synthetic Methods of Indole Derivatives : Named Reactions used in the synthesis of Indole Derivatives written by Kuldeep Singh and published by Notion Press. This book was released on with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indole is the foremost heterocyclic compound in the entire heterocyclic system. Some of the ring heterocyclics are formed when the benzene ring is fused to five or six-membered heterocyclic compounds at the second and third positions of the benzene ring. It may include indole, benzofuran, quinoline, isoquinoline. Indole plays an integral role in chemical, biological and pharmacological activities. Indole nuclei carry immense importance as it built proteins in the form of amino acid tryptophan and depicts the Skelton of indole alkaloids. Indole binds with high affinity with the multiple receptors. Due to its huge medical importance such as antimicrobial, antiproliferative, antiviral, antifungal, antioxidant, antidiabetic, antihistamine, anti-inflammatory, analgesic, anticancer, antitubercular, antihypertensive, antimalarial, anticholinesterase and many more indole is found to be invariably crucial to study. The medical importance of indole amuses researchers to synthesize diverse types of indole derivatives as it also flair some new therapeutic effects. Indole moiety is a subpart of radical scavengers are found commonly in the body. Indole not only has biological importance but also acquires so many industrial applications say dyes, flavor enhancers, agriculture etc. It also has a significant role in commodity markets.
Author : Richard J. Sundberg
Publisher : Elsevier
ISBN 13 : 0080534619
Total Pages : 193 pages
Book Rating : 4.0/5 (85 download)
Download or read book Indoles written by Richard J. Sundberg and published by Elsevier. This book was released on 1996-05-28 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials. - Includes systematic summaries of the most important methods for the construction of indoles from aromatic precursors - Discusses methods for preparing indoles by annelation of pyrroles - Covers methods for adding or modifying substituent groups, including methods for introducing the tryptamine and tryptophan side-chainsExamines reduction/oxidation reactions that are specific for indoles - Considers use of cycloaddition reactions for synthetic elaboration of indoles
Author : Gordon W. Gribble
Publisher : Springer Science & Business Media
ISBN 13 : 3642157327
Total Pages : 498 pages
Book Rating : 4.6/5 (421 download)
Download or read book Heterocyclic Scaffolds II: written by Gordon W. Gribble and published by Springer Science & Business Media. This book was released on 2010-10-09 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richard J. Sundberg Electrophilic Substitution Reactions of Indoles Tara L.S. Kishbaugh Reactions of Indole with Nucleophiles Erin Pelkey Metalation of Indole Jie Jack Li ∙ Gordon W. Gribble Metal-Catalyzed Cross-Coupling Reactions for Indoles Jeanese C. Badenock Radical Reactions of Indole Fariborz Firooznia ∙ Robert F. Kester ∙ Steven J. Berthel [2+2], [3+2] and [2+2+2] Cycloaddition Reactions of Indole Derivatives Robert F. Kester ∙ Steven J. Berthel ∙ Fariborz Firooznia [4+2] Cycloaddition Reactions of Indole Derivatives Jonathon S. Russel Oxindoles and Spirocyclic Variations: Strategies for C3 Functionalization Liangfeng Fu Advances in the Total Syntheses of Complex Indole Natural Products
Author : Stephen D. Clemans
Publisher :
ISBN 13 :
Total Pages : 91 pages
Book Rating : 4.:/5 (115 download)
Download or read book The Synthesis of Some Substituted 3- Indoles written by Stephen D. Clemans and published by . This book was released on 1967 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : 蔡志強
Publisher : Open Dissertation Press
ISBN 13 : 9781374757233
Total Pages : pages
Book Rating : 4.7/5 (572 download)
Download or read book Addition Reactions of Some Substituted Indoles with Dimethyl Acetylenedicarboxylate and Methyl Propiolate written by 蔡志強 and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Addition Reactions of Some Substituted Indoles With Dimethyl Acetylenedicarboxylate and Methyl Propiolate" by 蔡志強, Chi-keung, Michael, Choi, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b3123007 Subjects: Carbenes (Methylene compounds) Substitution reactions Indole Acetylene compounds
Author : Gordon W. Gribble
Publisher : John Wiley & Sons
ISBN 13 : 0470512180
Total Pages : 704 pages
Book Rating : 4.4/5 (75 download)
Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-08-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Author : Debabrata Maiti
Publisher : John Wiley & Sons
ISBN 13 : 3527346678
Total Pages : 450 pages
Book Rating : 4.5/5 (273 download)
Download or read book Remote C-H Bond Functionalizations written by Debabrata Maiti and published by John Wiley & Sons. This book was released on 2021-04-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to contemporary advancements in the field of distal C-H functionalizations An important and dynamic topic within the modern field of organic synthesis, selective functionalization of C-H bonds can be used in a variety of applications across the pharmaceutical and agrochemical industries. Remote C-H Bond Functionalizations presents an inclusive account of the most recent developments and potential applications of performing variegated functionalizations selectively at the distal positions of organic compounds. Featuring contributions by an international team of experts, this authoritative volume provides deep insight into distal functionalizations, including detailed discussion of mechanisms, the engineering of templates, and the design of strategies. The text covers a diverse range of topics including C-H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp2)-H, functionalization, transition metal catalyzed distal para-selective C-H functionalization, and much more. Reviewing contemporary advancements in the field while laying the foundation for future research, this important resource: Provides the most recent research and thorough coverage of the subject available in a single volume Offers practical information on C-H functionalizations in various industries Includes an up-to-date introduction to distal C-H functionalizations Remote C-H Bond Functionalizations is a must-read for every synthetic chemist, including chemists working with organometallics, organic chemists and researchers, and industrial chemists.
Author : Larry Roy Unger
Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4.:/5 (831 download)
Download or read book The Synthesis and Chemistry of 3-substituted Indoles and of Singlet Oxygen written by Larry Roy Unger and published by . This book was released on 1975 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yasamin Moazami
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.:/5 (841 download)
Download or read book Novel Methodology for the Synthesis of Substituted Indoles written by Yasamin Moazami and published by . This book was released on 2011 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herein, a novel approach is reported of the synthesis of substituted indole derivatives that utilizes a lithiation reaction of a substituted JV-alkyl benzyl aniline to yield a dilithio intermediate, which is then trapped with an ester. The reaction sequence utilizes an internal cyclization and a subsequent dehydration, to generate a substituted indole.
Author : Robert John Kempton
Publisher :
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.:/5 (23 download)
Download or read book The Synthesis of Some Substituted Indole-3-acetic Acids written by Robert John Kempton and published by . This book was released on 1969 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Brian Robinson
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (83 download)
Download or read book The Fischer Indole Synthesis written by Brian Robinson and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Laszlo Kurti
Publisher : Elsevier
ISBN 13 : 0080575412
Total Pages : 808 pages
Book Rating : 4.0/5 (85 download)
Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings
![Download I. [2 +2] Cycloaddition and Benzannulation of 2-iodoynamides and Application to the Construction of Highly Substituted Indoles PDF Online Free](https://books.google.com/books/content/images/frontcover/3LjADAEACAAJ?fife=w200-h370)
Author :
Publisher :
ISBN 13 :
Total Pages : 287 pages
Book Rating : 4.:/5 (94 download)
Download or read book I. [2 +2] Cycloaddition and Benzannulation of 2-iodoynamides and Application to the Construction of Highly Substituted Indoles written by and published by . This book was released on 2015 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis and reactions of 2-iodoynamides were investigated. 2-Iodoynamides undergo efficient and regioselective [2 + 2] cycloaddition with ketene to produce cyclobutenones that are useful synthetic building blocks. Reaction of 2-iodoynamides and vinylketenes generated in situ from cyclobutenones proceeds via a pericyclic cascade mechanism to produce highly substituted 2-iodoanilines. Tandem strategies for the synthesis of highly substituted indoles involving this benzannulation reaction were investigated. In addition, the synthesis of furo[2,3-g]thieno[2,3- e]indole, a new tetracyclic aromatic compound, was achieved via a strategy based on benzannulation with ynamides.
Author : Tlabo Caiphus Leboho
Publisher :
ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.:/5 (775 download)
Download or read book The Synthesis of 2- and 3-substituted Indoles written by Tlabo Caiphus Leboho and published by . This book was released on 2008 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
