Snake and Spider Toxins

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Author :
Publisher : Humana
ISBN 13 : 9781493998449
Total Pages : 0 pages
Book Rating : 4.9/5 (984 download)

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Book Synopsis Snake and Spider Toxins by : Avi Priel

Download or read book Snake and Spider Toxins written by Avi Priel and published by Humana. This book was released on 2019-10-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores techniques and protocols, across various biological disciplines, used to study snake and spider peptide toxins. The chapters in this book are organized into four parts and cover topics such as the use of toxins in drug development; analysis of bioactivity of complex mixtures like venom; extraction of venom glands and the production of toxins; characterization of toxins from the RNA level to the peptide structure; and the determination of the toxin’s biological function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Snake and Spider Toxins: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field.

Venomous

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Author :
Publisher : Macmillan + ORM
ISBN 13 : 0374712212
Total Pages : 219 pages
Book Rating : 4.3/5 (747 download)

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Book Synopsis Venomous by : Christie Wilcox

Download or read book Venomous written by Christie Wilcox and published by Macmillan + ORM. This book was released on 2016-08-09 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thrilling tale of encounters with nature’s masters of biochemistry From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world. Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out. Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated. Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.

Snake Venoms

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Author :
Publisher : Springer
ISBN 13 : 9789400764095
Total Pages : 0 pages
Book Rating : 4.7/5 (64 download)

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Book Synopsis Snake Venoms by : P. Gopalakrishnakone

Download or read book Snake Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2017-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Venomous Reptiles and Their Toxins

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Author :
Publisher :
ISBN 13 : 0199309396
Total Pages : 609 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Venomous Reptiles and Their Toxins by : Bryan Grieg Fry

Download or read book Venomous Reptiles and Their Toxins written by Bryan Grieg Fry and published by . This book was released on 2015 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Venom research and technology has advanced greatly, rapidly transforming our knowledge of reptile venoms. Research advances, like the development of molecular systematics, provide the framework necessary to reconstruct the evolutionary history of glands and fangs. Such research developments have expanded our understanding of venom's evolution and its usefulness in therapeutic development. The results of this punctuated toxin molecular evolutionary expansion include protein neofunctionalization. While these changes may impact antivenom efficacy, this molecular diversity also facilitates their usefulness in the development of novel drug therapies. Venomous Reptiles And Their Toxins brings together the world's leading toxinologists in this comprehensive study of the entire scope of reptile venoms, from clinical effects to evolution to drug design and development. The book contains detailed applied chapters on clinical care of the envenomed patient, ineffective traditional or modern remedies, occupational considerations involved in the maintenance of institutional venomous reptile collections, veterinary care for venomous reptiles and research methods used in venom research. This book also devotes a chapter to each toxin class found in reptile venoms, detailing the full trajectory of research on the peptide or protein in question. These chapters discuss each toxin's respective role in the envenomation process through to how each has been explored for their biomedical potential. This book is a unique resource for anyone working with venomous reptiles.

Handbook of Venoms and Toxins of Reptiles

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Author :
Publisher : CRC Press
ISBN 13 : 1420008668
Total Pages : 548 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Venoms and Toxins of Reptiles by : Stephen P. Mackessy

Download or read book Handbook of Venoms and Toxins of Reptiles written by Stephen P. Mackessy and published by CRC Press. This book was released on 2016-04-19 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Venoms and Toxins of Reptiles offers "one-stop shopping" to all biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation. This book

Characterization of Toxic Snake and Spider Venom Components

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Author :
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (194 download)

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Book Synopsis Characterization of Toxic Snake and Spider Venom Components by : Randal K. Tucker

Download or read book Characterization of Toxic Snake and Spider Venom Components written by Randal K. Tucker and published by . This book was released on 1987 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Use of Snake Venom Proteins

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Author :
Publisher : CRC Press
ISBN 13 : 9780849358463
Total Pages : 284 pages
Book Rating : 4.3/5 (584 download)

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Book Synopsis Medical Use of Snake Venom Proteins by : Kurt F. Stocker

Download or read book Medical Use of Snake Venom Proteins written by Kurt F. Stocker and published by CRC Press. This book was released on 1990-06-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fascinating book provides actual knowledge on evolution, anatomy habits, and classification of venomous snakes. It presents detailed, updated information on physicochemical, biochemical, and pharmacological characteristics of biomedically relevant snake venom proteins, their practical use and potential. This volume includes particular sections concerning neurotoxins and their application in neurophysiological and muscular research, snake venom proteins affecting the complement system, as well as the large field of snake venom components affecting the hemostatic and fibrinolytic system. Written in a comprehensive manner, this work communicates to the reader the importance of preventing the extinction of venomous snake species as the carriers of unique genetic information. This interesting book is a must for all who are involved with thrombosis, hemotology, toxinology, neurochemistry, as well as animal toxins within biological, medical or pharmaceutical education.

Experimental Contributions to the Toxicology of Rattle-snake Venom

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Author :
Publisher :
ISBN 13 :
Total Pages : 62 pages
Book Rating : 4.R/5 (6 download)

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Book Synopsis Experimental Contributions to the Toxicology of Rattle-snake Venom by : Silas Weir Mitchell

Download or read book Experimental Contributions to the Toxicology of Rattle-snake Venom written by Silas Weir Mitchell and published by . This book was released on 1868 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Venoms, Animal and Microbial Toxins

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889669912
Total Pages : 252 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Venoms, Animal and Microbial Toxins by : Jean-Marc Sabatier

Download or read book Venoms, Animal and Microbial Toxins written by Jean-Marc Sabatier and published by Frontiers Media SA. This book was released on 2021-07-09 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Venom

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Author :
Publisher : Smithsonian Institution
ISBN 13 : 1588344541
Total Pages : 207 pages
Book Rating : 4.5/5 (883 download)

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Book Synopsis Venom by : Ronald Jenner

Download or read book Venom written by Ronald Jenner and published by Smithsonian Institution. This book was released on 2017-10-17 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Venom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.

Neuroparasitology and Tropical Neurology

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Author :
Publisher : Elsevier Inc. Chapters
ISBN 13 : 012807969X
Total Pages : 38 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroparasitology and Tropical Neurology by : Oscar H. Del Brutto

Download or read book Neuroparasitology and Tropical Neurology written by Oscar H. Del Brutto and published by Elsevier Inc. Chapters. This book was released on 2013-07-03 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.

Natural Toxins 2

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461303613
Total Pages : 529 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Natural Toxins 2 by : Bal Ram Singh

Download or read book Natural Toxins 2 written by Bal Ram Singh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: From beach encounters, aquaculture perils, and processed-food poisoning to snake bites and biological warfare, natural toxins seem never to be far from the public's sight. A better understanding of toxins in terms of their origin, structure, structure-function relation ships, mechanism of action, and detection and diagnosis is of utmost importance to human and animal food safety, nutrition, and health. In addition, it is now clear that many of the toxins can be used as scientific tools to explore the molecular mechanism of several biological processes, be it a mechanism involved in the function of membrane channels, exocytosis, or cytotoxicity. Several of the natural toxins have also been approved as therapeutic drugs, which has made them of interest to several pharmaceutical companies. For example, botulinum neurotoxins, which have been used in studies in the field of neurobiology, have also been used directly as therapeutic drugs against several neuromus cular diseases, such as strabismus and blepherospasm. Toxins in combination with modem biotechnological approaches are also being investigated for their potential use against certain deadly medical problems. For example, a combination of plant toxin ricin and antibodies is being developed for the treatment of tumors. The great potential of natural toxins has attracted scientists of varying backgrounds-pure chemists to cancer biologists-to the study of fundamental aspects of the actions of these toxins.

Medical Toxicology

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1838802770
Total Pages : 350 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Medical Toxicology by : Pınar Erkekoglu

Download or read book Medical Toxicology written by Pınar Erkekoglu and published by BoD – Books on Demand. This book was released on 2021-02-03 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical toxicology is a sub-branch of toxicology concerned with the diagnosis, management, and prevention of poisoning and other adverse effects of drugs, cosmetics, personal care products, occupational and environmental toxicants, and biological agents. Poisoning with drugs, herbs, venoms, and toxins is a significant global public health problem. Medical toxicologists are involved in the assessment and treatment of acute or chronic poisoning, substance abuse, adverse drug reactions, drug overdoses, envenomation, industrial accidents, and other chemical exposures. As such, there is a pressing need for safe and specific antidotes, as many antidotes currently in use have a relatively low margin of safety or therapeutic index. This book focuses on poisonings with drugs, venoms, toxins, interaction in clinics, antidotes, and forensics. It provides qualified scientific knowledge on different aspects of medical toxicology, drug and substance abuse, clinical interactions between drugs and herbs, antidotes, antidote networks, and forensic toxicology.

Spider Venoms

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Author :
Publisher : Springer
ISBN 13 : 9789400763883
Total Pages : 0 pages
Book Rating : 4.7/5 (638 download)

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Book Synopsis Spider Venoms by : P. Gopalakrishnakone

Download or read book Spider Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2016-05-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

U.S. Guide to Venomous Snakes and Their Mimics

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Author :
Publisher : Skyhorse Publishing Inc.
ISBN 13 : 1616081821
Total Pages : 161 pages
Book Rating : 4.6/5 (16 download)

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Book Synopsis U.S. Guide to Venomous Snakes and Their Mimics by : Scott Shupe

Download or read book U.S. Guide to Venomous Snakes and Their Mimics written by Scott Shupe and published by Skyhorse Publishing Inc.. This book was released on 2011-02-23 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rattlesnake? Copperhead? Cottonmouth? When to stay and when to run from nature s coolest...

Snake Venoms

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642669131
Total Pages : 1162 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Snake Venoms by : C.-Y. Lee

Download or read book Snake Venoms written by C.-Y. Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has been a period of explosion of knowledge on the chemistry and pharmacology of snake toxins. Thanks to the development of protein chemistry, nearly a hundred snake toxins have been purified and sequenced, representing one of the largest families of sequenced proteins. Moreover, the mode of action of these toxins has been largely elucidated by the concerted efforts of pharmacologists, electro physiologists, and biochemists. As a result of these studies, some of the snake toxins, e.g., a-bungarotoxin and cobra neurotoxins, have been extensively used as specific markers in the study of the acetylcholine receptors. Indeed, without the discovery of these snake toxins, our knowledge of the structure and function of nicotinic acetylcholine receptors would not have advanced so rapidly. The contribution of snake venom research to the biomedical sciences is not limited to the study of cholinergic receptors. Being one of the most concentrated enzyme sources in nature, snake venoms are also valuable tools in biochemical research. Venom phosphodiesterase, for example, has been widely used for structural studies of nucleic acids; proteinase, for the sequence studies of proteins and pep tides ; phospholipase A , for lipid research; and L-amino acid oxidase for identifying optical z isomers of amino acids. Furthermore, snake venoms have proven to be useful agents for clarifying some basic concepts on blood coagulation and some venom enzymes, e.g., thrombin-like enzymes and pro coagulants have been used as therapeutic agents.

The Art and Science of Poisons

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1681086972
Total Pages : 282 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis The Art and Science of Poisons by : Olen R. Brown

Download or read book The Art and Science of Poisons written by Olen R. Brown and published by Bentham Science Publishers. This book was released on 2018-06-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poisons, due to their lethal nature, invoke a sense of fear in humans. Yet, they have also impacted other aspects of human life. Poisons have been used by nomadic hunters to kill their prey, by scientists to explore complex biochemical mechanisms of the body, by physicians to lower cholesterol and to kill cancer cells, by farmers and the general public to destroy pests, by the evil minded for homicide, and by tyrants as weapons of war. The Art and Science of Poisons presents two facets of poisons: the science behind them and their place in history and art. The science of poisons describes their biochemistry and how they kill. The science story voyages into the sub-microscopic world of atoms, molecules, and cells. Only there can we see the true miracles and mysteries of life and death. Chapters in the book explore poisons from snakes, spiders, scorpions, sea creatures, as well as poisons made by humans in the laboratory, and those which are derived from beautiful plants. The art of poisons, on the other hand, encompasses everything else about these agents that conjures up the image of the skull and crossbones. This side of the story explores the legends and tales of intrigue and surreptitious deaths of well-known personalities such as Socrates, Cleopatra, Hitler, and many more. General readers with a curiosity about science and an interest in history and human nature will enjoy both facets presented in this brief, yet varied exploration into the world of poisons.