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Small Animal Imaging Technological And Methodological Advances To Improve The Translational Power
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Book Synopsis Small animal imaging: Technological and methodological advances to improve the translational power by : Monique R. Bernsen
Download or read book Small animal imaging: Technological and methodological advances to improve the translational power written by Monique R. Bernsen and published by Frontiers Media SA. This book was released on 2023-01-13 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Small Animal Imaging by : George C. Kagadis
Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Book Synopsis Small Animal Imaging by : Fabian Kiessling
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer. This book was released on 2017-05-22 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Book Synopsis Small-Animal SPECT Imaging by : Matthew A. Kupinski
Download or read book Small-Animal SPECT Imaging written by Matthew A. Kupinski and published by Springer Science & Business Media. This book was released on 2007-05-27 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.
Book Synopsis Small Animal Imaging by : Fabian Kiessling
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer Science & Business Media. This book was released on 2010-11-29 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study planning, animal handling, and the cost-effective performance of small animal imaging. Cross-calibration methods, data postprocessing, and special imaging applications are also considered in depth. This is the first book to cover all the practical basics in small animal imaging, and it will prove an invaluable aid for researchers, students, and technicians.
Book Synopsis The Handbook of Medicinal Chemistry by : Simon E Ward
Download or read book The Handbook of Medicinal Chemistry written by Simon E Ward and published by Royal Society of Chemistry. This book was released on 2023-02-03 with total page 1051 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.
Book Synopsis Molecular Imaging in Oncology by : Otmar Schober
Download or read book Molecular Imaging in Oncology written by Otmar Schober and published by Springer Science & Business Media. This book was released on 2012-11-28 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPECT tracers as well as multimodality probes. Preclinical studies are then discussed in detail, with particular attention to multimodality imaging. In the third section, diverse clinical applications are presented, and the book closes by looking at future challenges. This handbook will be of value to all who are interested in the revolution in diagnostic oncology that is being brought about by molecular imaging.
Book Synopsis Diagnostic Ultrasound in Small Animal Practice by : Paddy Mannion
Download or read book Diagnostic Ultrasound in Small Animal Practice written by Paddy Mannion and published by Wiley-Blackwell. This book was released on 2006-06-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new version of Frances Barr’s classic introductory text, Diagnostic Ultrasound in the Dog and Cat, has now been revised and expanded to cover the considerable technological and knowledge based advances since the first book was published in 1990. With contributions from leading subject experts, this new book covers both the theoretical principles behind the use of ultrasound in small animal practice and the practical approach to image interpretation. In-keeping with the user-friendly style of Frances Barr’s book, the book is extensively illustrated with photographs and accompanying line drawings. Organised around body systems, each chapter covers imaging procedures, normal appearances, abnormal appearances/diseases and specific conditions. Exotic animals, such as rabbits and reptiles are also included, as are new Doppler techniques. This practical guide is essential reading for all those involved in small animal imaging.
Author :United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development Publisher : ISBN 13 : Total Pages :1716 pages Book Rating :4.:/5 (9 download)
Book Synopsis Energy and Water Development Appropriations for 2008: Dept. of Energy FY 2008 budget justifications: science, nuclear waste disposal, defense nuclear waste disposal by : United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Download or read book Energy and Water Development Appropriations for 2008: Dept. of Energy FY 2008 budget justifications: science, nuclear waste disposal, defense nuclear waste disposal written by United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development and published by . This book was released on 2007 with total page 1716 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modern CNS Drug Discovery by : Rudy Schreiber
Download or read book Modern CNS Drug Discovery written by Rudy Schreiber and published by Springer Nature. This book was released on 2021-06-17 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Book Synopsis Cone Beam Computed Tomography by : Chris C. Shaw
Download or read book Cone Beam Computed Tomography written by Chris C. Shaw and published by Taylor & Francis. This book was released on 2014-02-14 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional computed tomography (CT) techniques employ a narrow array of x-ray detectors and a fan-shaped x-ray beam to rotate around the patient to produce images of thin sections of the patient. Large sections of the body are covered by moving the patient into the rotating x-ray detector and x-ray source gantry. Cone beam CT is an alternative te
Book Synopsis Handbook of Obesity, Two-Volume Set by : George A. Bray
Download or read book Handbook of Obesity, Two-Volume Set written by George A. Bray and published by CRC Press. This book was released on 2024-01-09 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2 volume set comprises of the 4th edition of Volume 1 and the 5thth edition of Volume 2. The fifth edition of Volume 1 of Handbook of Obesity written by global experts covers the basic science aspects under the broad topic areas of epidemiology, etiology, and pathophysiology of obesity. Divided into 5 sections and detailed in 66 chapters, this edition covers the important advances occurring over the past decades. With a focus on science of obesity and factors participating in the etiology of obesity, this topic is studied from biological, behavioural, and environmental perspectives. Volume 1 is structured into 5 parts: Part 1 focuses on the history, definitions, and prevalence of the obesity. It identifies the historical references to excess weight, obesity in art and literature, direct and surrogate measurements of adiposity and obesity related traits, epidemiology of obesity around the globe, and age, sex, and ethnic variation completes this part of the volume. Part 2 explains the biological determinants of obesity. It explains the bioenergetics, energy dissipation mechanisms and exposure to experimental overfeeding, genetic and epigenetic evidence, metabolic rates, energy expenditure and energy partitioning, and the evidence on infections and adiposity. Part 3 describes the behavioral determinants of obesity. It deals with chapters related to food, beverages, and ingestive behavior, dealing with smoking, breast-feeding, and sleep duration and pattern, and sedentary behavior, occupational work, and leisure-time physical activity and obesity. Part 4 comprises of chapters explaining the environmental, social, and cultural determinants of obesity. The chapters in this section focus on the role of agriculture and the food industry in the current obesity epidemic, social and economic aspects of obesity, and ethnic and cultural differences, and environmental pollutants. Part 5 of this volume discusses the health consequences of obesity. The chapters address important topics such obesity and heart disease, lipoprotein metabolism, insulin resistance and diabetes, metabolic syndrome, cancer, hepatic biology, pulmonary functions, and arthritis and gout, mental health and quality of life, growth and health disorders in pediatric populations, and on bias and discrimination affecting the obese persons. Volume 2 of the 5th Edition of the Handbook of Obesity spotlights on clinical applications for evaluation, diagnosis, prevention, and treatment of obesity. It covers on the several major developments occurred between the previous and the new edition, including the effect of SARS-CoV-2 on people with obesity, the concept of "Precision Medicine", and new medications approved by USFDA aiding patients with obesity weight loss of 15 to 20%. This volume is structured into 5 parts: Part 1 provides insights from evolution on changes in diet and physical activity, and the implications and results for preventing obesity, health care costs associated with obesity and the cost-effectiveness of obesity prevention and treatment. Part 2 deals with evaluation of overweight patients, approaches for classifying obesity and using this knowledge to evaluate patients, and addressing ethnic and racial considerations in evaluating patients with obesity. Part 3 explains the impact of lifestyle in managing obesity, which include behavioural management, diet, dietary composition, and meal timing, and the effects of physical activity and exercise in weight loss and weight loss maintenance. Part 4 is focused on medications in the management of obesity. This includes drug selection, various classes of drugs, combination of drugs affecting weight loss, effect of herbal agents on weight loss and treatment of obesity in pediatric populations, genetic diseases causing obesity and the role of drugs in treating the dyslipidemias. Part 5 discusses bariatric surgery, its history, procedure and effects in details, and other surgical techniques including electric stimulation of the vagus nerve, gastric balloons, intestinal liners, and liposuction.
Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Book Synopsis Image Fusion in Preclinical Applications by : Claudia Kuntner-Hannes
Download or read book Image Fusion in Preclinical Applications written by Claudia Kuntner-Hannes and published by Springer. This book was released on 2019-01-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research. The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications. Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research.
Book Synopsis Basic Science of PET Imaging by : Magdy M. Khalil
Download or read book Basic Science of PET Imaging written by Magdy M. Khalil and published by Springer. This book was released on 2016-11-07 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Author :United States. Congress. Senate. Office of Management and Budget. Executive Office of the President Publisher : ISBN 13 :9780160944192 Total Pages :1886 pages Book Rating :4.9/5 (441 download)
Book Synopsis 2017 Catalog of Federal Domestic Assistance by : United States. Congress. Senate. Office of Management and Budget. Executive Office of the President
Download or read book 2017 Catalog of Federal Domestic Assistance written by United States. Congress. Senate. Office of Management and Budget. Executive Office of the President and published by . This book was released on 2017 with total page 1886 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifies and describes specific government assistance opportunities such as loans, grants, counseling, and procurement contracts available under many agencies and programs.
Book Synopsis Biological Applications of Nanoparticles by : Biplab Sarkar
Download or read book Biological Applications of Nanoparticles written by Biplab Sarkar and published by Springer Nature. This book was released on 2024-01-13 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook for graduate and postgraduate students provides comprehensive applications of nanoparticles in medicine, agriculture, and environmental sciences. The initial chapter covers basic topics related to types, synthesis, structure, and properties of various nanoparticles. It further discusses the wide range of applications of nanoparticles in medicine, agriculture, and the environment. The book presents nano-electronic biosensors that are used to diagnose and monitor the progression of human diseases. It summarizes the opportunities and challenges of nanotechnology in the agriculture and food sector highlighting the scientific, technical, regulatory, safety, and societal impacts. Additionally, it illustrates the applications of nanotechnology in the field of aquaculture medicine, bioinformatics and food technology. The textbook examines the development and administration of nano-medicines , their applications, advantages, and limitations for the treatment and prophylaxis of a broad range of diseases. Lastly, the textbook explores the recent advances in the field of nanobusiness and nanotechnology issues in intellectual property management( IPR).
