Simulating Protein Adsorption For Experimental Comparison

Download Simulating Protein Adsorption For Experimental Comparison full books in PDF, epub, and Kindle. Read online Simulating Protein Adsorption For Experimental Comparison ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Simulating Protein Adsorption for Experimental Comparison

Author : Michael Deighan
Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.:/5 (894 download)

DOWNLOAD NOW!

Book Synopsis Simulating Protein Adsorption for Experimental Comparison by : Michael Deighan

Download or read book Simulating Protein Adsorption for Experimental Comparison written by Michael Deighan and published by . This book was released on 2014 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many biological processes and technological applications involve proteins coming into contact with a solid surface. Generally, we know that proteins experience some degree of conformational change at the solid/liquid interface, and can measure these changes in the lab. However, while many experimental techniques exist for characterizing surface-bound proteins, none have been able to resolve high-precision structures. Computer simulation offers a unique route to determining how proteins adsorb. Herein, we apply a popular statistical sampling technique - Parallel Tempering Metadynamics - to all-atom molecular dynamics simulations of ex- plicitly solvated proteins interacting with solid surfaces. We show that by biasing specific degrees of freedom - or collective variables - a protein can be influenced to exhaustively explore conformational space both on and off a surface. The results from these simulations can be post-processed to reveal details such as: surface- bound conformations, orientations, and finer structural details like interatomic distances and Ramachandran angles - which, in turn, can be compared to, and validated by, experimental measurements. Ultimately, this work should convey the descriptive power that can arise from a mutually beneficial partnership between surface science and computer simulation in the context of biomolecular adsorption.

Computational Bioengineering

Author : Guigen Zhang
Publisher : CRC Press
ISBN 13 : 1466517565
Total Pages : 508 pages
Book Rating : 4.4/5 (665 download)

DOWNLOAD NOW!

Book Synopsis Computational Bioengineering by : Guigen Zhang

Download or read book Computational Bioengineering written by Guigen Zhang and published by CRC Press. This book was released on 2015-04-01 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la

Modeling Transport and Protein Adsorption in Microfluidic Systems

Author : Craig Finch
Publisher :
ISBN 13 :
Total Pages : 133 pages
Book Rating : 4.:/5 (855 download)

DOWNLOAD NOW!

Book Synopsis Modeling Transport and Protein Adsorption in Microfluidic Systems by : Craig Finch

Download or read book Modeling Transport and Protein Adsorption in Microfluidic Systems written by Craig Finch and published by . This book was released on 2011 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass transport limitations and surface interactions are important phenomena in microfluidic devices. The flow of water is laminar at small scales and the absence of turbulent mixing can lead to transport limitations, especially for reactions that take place at surfaces. Microscale devices have a high ratio of surface area to volume, and proteins are known to adsorb preferentially at interfaces. Protein adsorption plays a significant role in biology by mediating critical processes such as the attachment of cells to surfaces, the immune response and the coagulation of blood. Simulation tools that can quantitatively predict transport and protein adsorption will enable the rational design of microfluidic devices for biomedical applications. Two-dimensional random sequential adsorption (RSA) models are widely used to model the adsorption of proteins on surfaces. As Brownian dynamics simulations have become popular for modeling protein adsorption, the interface model has changed from two-dimensional to three-dimensional. Brownian dynamics simulations were used to model the diffusive transport of hard-sphere particles in a liquid and the adsorption of the particles onto a uniform surface. The configuration of the adsorbed particles was analyzed to quantify the chemical potential near the surface, which was used to derive a continuum model of adsorption that incorporates the results from the Brownian dynamics simulations. The equations of the continuum model were discretized and coupled to a conventional computational fluid dynamics (CFD) simulation of diffusive transport to the surface. The kinetics of adsorption predicted by the continuum model closely matched the results from the Brownian dynamics simulation. This new model allows the results from mesoscale simulations to be used as a boundary condition for micro- or macro-scale CFD simulations of transport and protein adsorption in practical devices. Continuum models were used to interpret experimental measurements of the kinetics of protein adsorption. A Whispering Gallery Mode (WGM) biosensor was constructed and used to measure the adsorption of fibronectin (FN) and glucose oxidase (GO) onto several types alkysilane self-assembled monolayers (SAMs). Computational fluid dynamics was used to model the transport of protein in the flow cell of the biosensor. Various models were fitted to the experimental data, taking into account the transport limitations predicted by the CFD simulations. The fitted parameter values and the quality of fit of the various models were analyzed to test hypotheses about the mechanisms of adsorption. Cells were cultured on silane surfaces coated with FN to assess its biological activity, and a colorimetric assay was used to determine the enzymatic activity of the adsorbed glucose oxidase. The results of the GO activity assay were compared to the activity predicted by the models. The WGM biosensor, transport simulation and kinetic model fitting enabled new insights into the adsorption of proteins on functionalized surfaces at solution concentrations that were previously unattainable. The process of CFD simulation and experimental validation was applied to the design of microfluidic bioreactors for an in vitro tissue engineered model of an alveolus. The objective was to optimize the design of the microreactors so they operate more like plug flow reactors. Microreactors experience significant deviations from plug flow due to the high ratio of surface area to volume and the no-slip boundary condition at the walls of the chamber. Iterative CFD simulations were performed to optimize microfluidic structures to minimize the width of the residence time distributions of two types of chambers. Qualitative and quantitative visualization experiments with a dye indicator demonstrated that the CFD simulations accurately predicted the residence time distributions of the chambers. The use of CFD simulations greatly reduced the time and cost required to optimize the performance of the microreactors.

Development of a MATLAB® Model for Estimating the Amount of Protein Adsorption on Nanoparticles Covered with Poly (ethylene Glycol)

Author : Asavari Mehta
Publisher :
ISBN 13 :
Total Pages : 166 pages
Book Rating : 4.:/5 (936 download)

DOWNLOAD NOW!

Book Synopsis Development of a MATLAB® Model for Estimating the Amount of Protein Adsorption on Nanoparticles Covered with Poly (ethylene Glycol) by : Asavari Mehta

Download or read book Development of a MATLAB® Model for Estimating the Amount of Protein Adsorption on Nanoparticles Covered with Poly (ethylene Glycol) written by Asavari Mehta and published by . This book was released on 2014 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted drug delivery to cancerous tumors is a promising strategy for the treatment of cancer that mitigates the comprehensive, deleterious effects of current chemotherapy methods. The ability to selectively deliver cancer drugs to solid tumors can be achieved with constructs like micro-bubbles, micro-particles, nanoparticles and micelles that can carry and elute a conjugated drug. Moreover, poly (ethylene glycol) (PEG) can be incorporated into these delivery vehicles to provide a "stealth" coating that prevents the immune system from recognizing and prematurely eliminating them before the drug delivery is complete. The mechanism of immune system avoidance is accomplished when the incorporated PEG chains create a steric hindrance on the surface of the carrier particle that blocks the adsorption of blood plasma proteins onto the particle surface which consequently marks the particle as an antigen that must be removed by the immune system. Mathematically modeling the amount of plasma protein that can adsorb on a carrier particle with a PEG coating offers the benefit of expediting the selection of optimal values for three key parameters of particle fabrication: 1) PEG molecular weight, 2) PEG mass fraction and 3) carrier particle diameter which are essential to the creation of a PEG-coated, carrier particle that will minimize plasma protein adsorption. The basis for this mathematical model is a characteristic formula obtained from the research paper, Gref et al. [11], which describes the surface density threshold (SDT) representing the smallest area between PEG chains on the surface of a nanoparticle that creates the maximal blockage of protein adsorption. This SDT formulation, which contains all three key parameters mentioned above, was used to represent the amount of PEG in terms of molecular weight and mass fraction which was necessary for minimizing protein adsorption on nanoparticles that were also fabricated by the Gref study. In this current study, we use MATLAB® programming to combine the SDT formula and its corresponding experimental data from the Gref study to produced two curve-fit equations (effectively two separate models) that can be used to predict the protein adsorption values that occur for either changing molecular weight of PEG or changing mass fraction of PEG. The simulated values of protein adsorption resultant from variation of the given parameter was then directly compared to the experimental values obtained from Gref et al. in order to evaluate the model accuracy in estimating protein adsorption. The evaluation indicated that the success of the models in estimating protein adsorption was restricted to the parameter it was derived from, either PEG molecular weight or PEG mass fraction. In other words, the model to estimate protein adsorption due to variation of PEG molecular weight was not valid for estimating protein adsorption due to variation of PEG mass fraction and vice versa. Therefore examining changes in a parameter of interest must be done with the appropriate model. The correlation coefficients for the correlations tests showed R2 = 0.997 for PEG molecular weight and R2 = 0.988 for PEG mass fraction. Additionally, the models were not successful in estimating the protein adsorption values that corresponded to the average diameter of the nanoparticles because there was no experimental nanoparticle diameter data from Gref et al. [11] on which to base a curve-fitted estimation model. So, the two models in this study cannot account for a changing particle diameter. The two models developed in this study still require further refinement and validation with more experimental data other than that found in the study by Gref et al. [11]. In that sense, experiments with the parameter of particle diameter can be included to broaden the modeling perspective. Attempts were made to combine the two separate models of PEG molecular weight and PEG mass fraction to find a more universal metric that could establish the optimal parameters of nanoparticle fabrication that would minimize protein adsorption. One metric was to create a ratio of the two parameters and another was to create the product (multiplication) of the two parameters, and then develop a curve fit model for each metric. The results did not show promise because the variation of each metric did not produce a matched correlation to the data. In conclusion, researchers can inexpensively use this modeling tool as a starting point for designing PEG-coated, drug-carrier nanoparticles as it pertains to variation of PEG molecular weight or PEG mass fraction. The modeling presented in this study has extended the framework for simulating plasma protein adsorption on nanoparticles that would significantly inform the fabrication of effective, immuno-evasive, drug-eluting nanoparticles for cancer treatments.

Development and Use of Molecular Simulation Tools to Study the Structure and Function of Biomolecules at Interfaces

Author : Kayla G. Sprenger
Publisher :
ISBN 13 :
Total Pages : 195 pages
Book Rating : 4.:/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Development and Use of Molecular Simulation Tools to Study the Structure and Function of Biomolecules at Interfaces by : Kayla G. Sprenger

Download or read book Development and Use of Molecular Simulation Tools to Study the Structure and Function of Biomolecules at Interfaces written by Kayla G. Sprenger and published by . This book was released on 2017 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Predicting and controlling the biophysical chemistry of protein/host interactions remains a pressing challenge of high fundamental interest across many subfields in chemistry, engineering, and medicine. Our ability to (experimentally) probe interfacial interactions between a surface, polymer, or solvent and a biomolecule has increased due to high-resolution NMR and other spectroscopic techniques. However, new structural and mechanistic insights coming from experiments alone have been limited due to – in the case of the protein/liquid interface – the compounding challenges of simultaneously studying the protein/host interface and elucidating sequence specific interactions, and in the case of the protein/surface interface – the lack of a single unifying technique that can fully resolve the structure of an adsorbed protein. For the protein/liquid interface, the challenge is even worse in the case of synthetic frameworks such as ionic liquids (ILs) where the combinatorial design space of the solvent and protein sequence explodes beyond what could ever be feasibly considered in a laboratory. The field could be greatly advanced through the use of predictive, physics-based simulations; however, best practices of how to simulate protein interfacial adsorption and extract meaningful information about protein/host interactions from molecular simulations for direct experimental comparison, are still developing. Herein, we aim to address these challenges through the use of a variety of statistical enhanced sampling simulation techniques and novel analytical approaches. A number of systems are simulated, ranging from small model proteins adsorbing onto solid, idealized surfaces, to simulations of full proteins in complex solution environments. Ultimately, these simulations should lead to large improvements in the way we use computers to study multifaceted interfacial processes like protein adsorption, in addition to providing new fundamental insights into protein/host interactions.

Adsorption

Author : Jozsef Toth
Publisher : CRC Press
ISBN 13 : 0824744497
Total Pages : 887 pages
Book Rating : 4.8/5 (247 download)

DOWNLOAD NOW!

Book Synopsis Adsorption by : Jozsef Toth

Download or read book Adsorption written by Jozsef Toth and published by CRC Press. This book was released on 2002-05-10 with total page 887 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers an overview of the recent theoretical and practical results achieved in gas-solid, liquid-solid and gas-liquid adsorption research.

Authors and Friends

Author : Annie Fields
Publisher : Boston, Houghton
ISBN 13 :
Total Pages : 355 pages
Book Rating : 4.:/5 (76 download)

DOWNLOAD NOW!

Book Synopsis Authors and Friends by : Annie Fields

Download or read book Authors and Friends written by Annie Fields and published by Boston, Houghton. This book was released on 1897 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Biomaterials II

Author : Kevin Healy
Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!

Book Synopsis Comprehensive Biomaterials II by : Kevin Healy

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Foundations of Molecular Modeling and Simulation

Author : Randall Q Snurr
Publisher : Springer
ISBN 13 : 9811011281
Total Pages : 176 pages
Book Rating : 4.8/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Foundations of Molecular Modeling and Simulation by : Randall Q Snurr

Download or read book Foundations of Molecular Modeling and Simulation written by Randall Q Snurr and published by Springer. This book was released on 2016-06-01 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of select proceedings of the FOMMS 2015 conference. FOMMS 2015 was the sixth triennial FOMMS conference showcasing applications of theory of computational quantum chemistry, molecular science, and engineering simulation. The theme of the 2015 meeting was on Molecular Modeling and the Materials Genome. This volume comprises chapters on many distinct applications of molecular modeling techniques. The content will be useful to researchers and students alike.

Proceedings of the 2nd European Simulation Congress, Sept. 9-12, 1986, The Park Hotel, Antwerp, Belgium

Author : Philippe Geril
Publisher : VSP
ISBN 13 : 9789067640954
Total Pages : 832 pages
Book Rating : 4.6/5 (49 download)

DOWNLOAD NOW!

Book Synopsis Proceedings of the 2nd European Simulation Congress, Sept. 9-12, 1986, The Park Hotel, Antwerp, Belgium by : Philippe Geril

Download or read book Proceedings of the 2nd European Simulation Congress, Sept. 9-12, 1986, The Park Hotel, Antwerp, Belgium written by Philippe Geril and published by VSP. This book was released on 1986 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding and Controlling the Microstructure of Complex Foods

Author : D. Julian McClements
Publisher : Elsevier
ISBN 13 : 1845693671
Total Pages : 793 pages
Book Rating : 4.8/5 (456 download)

DOWNLOAD NOW!

Book Synopsis Understanding and Controlling the Microstructure of Complex Foods by : D. Julian McClements

Download or read book Understanding and Controlling the Microstructure of Complex Foods written by D. Julian McClements and published by Elsevier. This book was released on 2007-08-30 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is widely accepted that the creation of novel foods or improvement of existing foods largely depends on a strong understanding and awareness of the intricate interrelationship between the nanoscopic, microscopic and macroscopic features of foods and their bulk physiochemical properties, sensory attributes and healthfulness. With its distinguished editor and array of international contributors, Understanding and controlling the microstructure of complex foods provides a review of current understanding of significant aspects of food structure and methods for its control.Part one focuses on the fundamental structural elements present in foods such as polysaccharides, proteins and fats and the forces which hold them together. Part two discusses novel analytical techniques which can provide information on the morphology and behaviour of food materials. Chapters cover atomic force microscopy, image analysis, scattering techniques and computer analysis. Chapters in part three examine how the principles of structural design can be employed to improve performance and functionality of foods. The final part of the book discusses how knowledge of structural and physicochemical properties can be implemented to improve properties of specific foods such as ice-cream, spreads, protein-based drinks, chocolate and bread dough.Understanding and controlling the microstructure of complex foods is an essential reference for industry professionals and scientists concerned with improving the performance of existing food products and inventing novel food products. Reviews the current understanding of significant aspects of food structure and methods for its control Focuses on the fundamental structural elements present in foods such as proteins and fats and the forces that hold them together Discusses novel analytical techniques that provide information on the morphology and behaviour of food materials

The Vroman Effect

Author : C. H. Bamford
Publisher : VSP
ISBN 13 : 9789067641395
Total Pages : 218 pages
Book Rating : 4.6/5 (413 download)

DOWNLOAD NOW!

Book Synopsis The Vroman Effect by : C. H. Bamford

Download or read book The Vroman Effect written by C. H. Bamford and published by VSP. This book was released on 1992-12-01 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of specific antibodies as probes and detectors for adsorbed proteins by Dr. Leo Vroman and co-workers in the 1960s and 1970s confirmed his earlier observations and suspicions that blood protein adsorption involved a hierarchical series of collision, adsorption, and exchange processes. These observations and concepts were confirmed by other scientists and came to be known as 'the Vroman effect'. The core concept of the Vroman effect admits many approaches and over-reaches complex and not fully resolved questions of enzymology, transport phenomena, the statistical mechanics of protein conformation, longrange forces in liquids, and surface physics. This volume contains the presentations from the symposium which was held in honour of the 75th birhday of Dr. Leo Vroman, in Gouda, The Netherlands, and deals with various aspects of the Vroman effect.

Advanced Modelling and Simulation in the Chemical and Biochemical Process Industry

Author : Sudip Chakraborty
Publisher : CRC Press
ISBN 13 : 1040148913
Total Pages : 175 pages
Book Rating : 4.0/5 (41 download)

DOWNLOAD NOW!

Book Synopsis Advanced Modelling and Simulation in the Chemical and Biochemical Process Industry by : Sudip Chakraborty

Download or read book Advanced Modelling and Simulation in the Chemical and Biochemical Process Industry written by Sudip Chakraborty and published by CRC Press. This book was released on 2024-10-30 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Modelling and Simulation in the Chemical and Biochemical Process Industry explores modelling and simulation of chemical and biochemical processes at the industrial scale using a variety of approaches. Particular attention is devoted to simulations in different scales, which help achieve a wide-spectrum and more efficient analysis of several problems, ranging from the design of novel materials to the optimization of industrial processes as a function of the operating conditions. This book not only covers optimization with experimental data but also offers readers a thorough understanding and analysis of different parameters of a whole process stream. Covers a wide range of advanced modelling and simulation of chemical technologies: ab initio, atomistic molecular dynamics (MD), Lattice-Boltzmann (LB), dissipative particle dynamics (DPD), computational fluid dynamics (CFD), and finite element (FEM) Addresses issues associated with process control in different phases of the chemical industry Features modelling approaches that allow the design of novel processes/materials in a faster and more reliable way This book will be of interest to researchers and advanced readers in chemical, biochemical, environmental, and materials engineering and industrial chemistry.

Issues in Chemistry and General Chemical Research: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464963290
Total Pages : 10508 pages
Book Rating : 4.4/5 (649 download)

DOWNLOAD NOW!

Book Synopsis Issues in Chemistry and General Chemical Research: 2011 Edition by :

Download or read book Issues in Chemistry and General Chemical Research: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 10508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Chemistry and General Chemical Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemistry and General Chemical Research. The editors have built Issues in Chemistry and General Chemical Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemistry and General Chemical Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemistry and General Chemical Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Nanomedicine

Author :
Publisher : Elsevier
ISBN 13 : 0857096443
Total Pages : 705 pages
Book Rating : 4.8/5 (57 download)

DOWNLOAD NOW!

Book Synopsis Nanomedicine by :

Download or read book Nanomedicine written by and published by Elsevier. This book was released on 2012-10-19 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications. After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement. With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings Reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering

Hemeproteins—Advances in Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481688596
Total Pages : 509 pages
Book Rating : 4.4/5 (816 download)

DOWNLOAD NOW!

Book Synopsis Hemeproteins—Advances in Research and Application: 2013 Edition by :

Download or read book Hemeproteins—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemeproteins—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Globins. The editors have built Hemeproteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Globins in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemeproteins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biological Interactions on Materials Surfaces

Author : David A. Puleo
Publisher : Springer Science & Business Media
ISBN 13 : 0387981616
Total Pages : 438 pages
Book Rating : 4.3/5 (879 download)

DOWNLOAD NOW!

Book Synopsis Biological Interactions on Materials Surfaces by : David A. Puleo

Download or read book Biological Interactions on Materials Surfaces written by David A. Puleo and published by Springer Science & Business Media. This book was released on 2009-06-26 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.