Signal Transduction in Mast Cells and Basophils

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Publisher : Springer Science & Business Media
ISBN 13 : 1461221544
Total Pages : 438 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Signal Transduction in Mast Cells and Basophils by : Ehud Razin

Download or read book Signal Transduction in Mast Cells and Basophils written by Ehud Razin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focussing on the molecular mechanisms that govern mast cell and basophil cell biology and function, this book also provides a comprehensive summary of the field of signal transduction, giving insights into areas that have therapeutic potential. It gives detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide readers with an up-to-date account of a topic whose rapid progress makes conventional information gathering difficult.

Proceedings of the 4th International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils

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Publisher :
ISBN 13 :
Total Pages : 205 pages
Book Rating : 4.:/5 (175 download)

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Book Synopsis Proceedings of the 4th International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils by : International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils (4, 2001, Bethesda, Md.)

Download or read book Proceedings of the 4th International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils written by International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils (4, 2001, Bethesda, Md.) and published by . This book was released on 2002 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mast Cells and Basophils

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Author :
Publisher : Academic Press
ISBN 13 : 0080535852
Total Pages : 738 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Mast Cells and Basophils by : Gianni Marone

Download or read book Mast Cells and Basophils written by Gianni Marone and published by Academic Press. This book was released on 2000-05-25 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils

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Publisher :
ISBN 13 :
Total Pages : 5 pages
Book Rating : 4.:/5 (314 download)

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Book Synopsis Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils by : International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils. 4, 2001, Bethesda, Md..

Download or read book Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils written by International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils. 4, 2001, Bethesda, Md.. and published by . This book was released on 2002 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:

IgE Receptor (FcεRI) Function in Mast Cells and Basophils

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662220229
Total Pages : 298 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis IgE Receptor (FcεRI) Function in Mast Cells and Basophils by : Majed M. Hamawy

Download or read book IgE Receptor (FcεRI) Function in Mast Cells and Basophils written by Majed M. Hamawy and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The high affinity IgE receptor (FceRI) plays a central role in allergic diseases including asthma, allergic rhinitis, atopic dermatitis, food and drug allergy. Manipulating the function of this receptor is important for controlling the onset of allergic diseases. Written by leading scientists in the field, this book is the first comprehensive monograph to cover various aspects of FceRI structure, signal transduction and function. Thus, the book is valuable for researchers/students working on FceRI and on other receptors. In addition, clinicians who are concerned with broadening their knowledge of the FceRI role in allergic diseases will find this book useful.

Mast Cells in Allergic Diseases

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805579489
Total Pages : 233 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Mast Cells in Allergic Diseases by : Hirohisa Saito

Download or read book Mast Cells in Allergic Diseases written by Hirohisa Saito and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the editors have focused on the roles of mast cells in allergic diseases and discuss the future direction of discovering drugs. Another implication of this book is to understand mast cells at the system level. System biology is a research category to understand biology at the system level by examining the structure and dynamics of cellular and organismal functions, rather than the characteristics of isolated parts of a cell or organism.

Human Basophils and Mast Cells

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Human Basophils and Mast Cells by : Gianni Marone

Download or read book Human Basophils and Mast Cells written by Gianni Marone and published by . This book was released on 1995 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mast Cells and Basophils

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470030518
Total Pages : 274 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Mast Cells and Basophils by : Derek J. Chadwick

Download or read book Mast Cells and Basophils written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2006-01-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils

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Publisher :
ISBN 13 :
Total Pages : 205 pages
Book Rating : 4.:/5 (57 download)

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Book Synopsis Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils by : Juan Rivera

Download or read book Proceedings of the Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils written by Juan Rivera and published by . This book was released on 2002 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunopharmacology of Mast Cells and Basophils

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Author :
Publisher : Academic Press
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunopharmacology of Mast Cells and Basophils by : John C. Foreman

Download or read book Immunopharmacology of Mast Cells and Basophils written by John C. Foreman and published by Academic Press. This book was released on 1993-11-29 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a steady and continued research effort directed to understanding both the function and the role of mast cells and basophils ever since these cells were first described at the end of the nineteenth century. One of the most significant advances has perhaps been the appreciation of the fact that mast cells do not represent a single homogenous population of cells: they display heterogeneity at the morphological, biochemical and functional levels. The one characteristic that unites all types of mast cells and basophils appears to be the possession of the high affinity membrane receptor for immunoglobulin E, through which the cells may be stimulated. This volume begins with a review of the origin and development of mast cells and basophils. It continues by reviewing our knowledge of the stimuli to mast cells and basophils and the biochemical mechanisms which link the signal generated by stimulus to the response machinery of the cell. Further chapters deal with the drug control of mast cell and basophil responses, the heterogeneity of the cells' functions and the mediators' release by the cells, along with the morphological aspects of the cells' function. This book is completed by a selection of examples which examine the role of the mast cells or basophils in lung, skin and gastrointestinal tract. However, the role of the mast cell with regard to normal physiology, remains an open question. This book aims to provide an up-to-date account of mast cell and basophil biology, together with an insight into the functional relevance of these cells in some tissue types.

Ultrastructure of Mast Cells and Basophils

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805578644
Total Pages : 377 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Ultrastructure of Mast Cells and Basophils by : Ann M. Dvorak

Download or read book Ultrastructure of Mast Cells and Basophils written by Ann M. Dvorak and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the author reviews the ultrastructural studies of basophils and mast cells performed since the publication of an earlier monograph in 1991. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. Including more than 180 excellent micrographs, this book will be of interest to basic scientists in immunology, cell biology, secretion and angiogenesis research, and histochemistry. As mast cells and basophils play a crucial role in various diseases, it will be essential reading for allergists, immunologists, dermatologists, hematologists, gastroenterologists, rheumatologists, neurologists, pathologists, pulmonologists, and cardiologists.

Basophil and Mast Cell Degranulation and Recovery

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306437526
Total Pages : 436 pages
Book Rating : 4.4/5 (375 download)

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Book Synopsis Basophil and Mast Cell Degranulation and Recovery by : Ann M. Dvorak

Download or read book Basophil and Mast Cell Degranulation and Recovery written by Ann M. Dvorak and published by Springer Science & Business Media. This book was released on 1991-08-31 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basophils and mast cells are similar but unique secretory cells with a well-documented role in immediate-hypersensitivity reactions. The presence of these cells in various cell mediated hypersensitivity reactions, in tissues of multiple diseases, and as a component of the host reaction to injury and repair in numerous circumstances is well known. Release of stored and newly generated mediators of inflammation from basophils and mast cells contributes to the cascade of pathogenetic events in circumstances under which these release reactions occur. Despite insights acquired through studies of these pathologic events, the role of basophils and mast cells and their secretory products in health is not known. In this book, I review much of the structural information regarding basophils and mast cells of multiple species. Ultrastructural studies of rat mast cells historically precede and quantitatively exceed similar studies of basophils and mast cells of other species. Therefore, I first review these background studies as an entity. Then I discuss the contents of two prominent organelles-granules and lipid bodies-in basophils and mast cells of several species. The ultrastructural morphology of basophils and mast cells in three species is presented in detail to establish appropriate guidelines for their recognition and to provide general rules for analysis which are appropriate for the identification of these cells in other species as well.

Human Basophils and Mast Cells

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Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Human Basophils and Mast Cells by : Gianni Marone

Download or read book Human Basophils and Mast Cells written by Gianni Marone and published by S. Karger AG (Switzerland). This book was released on 1995 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Expert contributions cover disorders, such as mastocytosis and respiratory and cutaneous allergy, which are known to be associated with these cells. The less well-known involvement of the latter in atherosclerosis and gastrointestinal, cardiac, rheumatic and neoplastic diseases is emerging as an area of considerable interest as several informative chapters show. Written by clinical investigators specialising in diseases related to mast cells and basophils, this volume will be stimulating reading for those working in allergy, immunology, biochemistry, and respiration."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Basophils and Mast Cells

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Author :
Publisher : Springer Nature
ISBN 13 : 1071606964
Total Pages : 379 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Basophils and Mast Cells by : Bernhard F. Gibbs

Download or read book Basophils and Mast Cells written by Bernhard F. Gibbs and published by Springer Nature. This book was released on 2020-08-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and new chapters to build on and extend the strengths of the first edition. Chapters guide readers through basic biology of basophils, obtaining the cells by purification, culture of stem cells progenitors, peripheral CD34+ stem cell-derived mast cells, basophils from CD34+ progenitors, diagnostic applications, gene expression patterns in basophils, roles of basophils in different asthma phenotypes, knockout, and disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Basophils and Mast Cells: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Mast Cell Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 1441995331
Total Pages : 312 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Mast Cell Biology by : Alasdair M. Gilfillan

Download or read book Mast Cell Biology written by Alasdair M. Gilfillan and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.

Deciphering new molecular mechanisms of mast cell activation

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Author :
Publisher : Frontiers E-books
ISBN 13 : 2889191869
Total Pages : 135 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Deciphering new molecular mechanisms of mast cell activation by : Ulrich Blank

Download or read book Deciphering new molecular mechanisms of mast cell activation written by Ulrich Blank and published by Frontiers E-books. This book was released on 2014-03-20 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells are tissue-localized cells that play an important role in immunity and inflammation. Following an offensive event they act as cellular sensors that via the activation of cell surface receptors launch a cellular response culminating in the release of a whole set of inflammatory mediators and products. This response is initially destined to restore tissue homeostasis, but in case of chronic injury or deregulation also promotes pathology. To further understand the action of mast cells in their environmental context it is necessary to decipher the molecular mechanisms of their activation as well as the ensuing cellular responses. This will allow identification of new strategies to promote their beneficial actions or, at the contrary, to interfere with their pathological consequences. While in the past many studies have focused on responses engaged by high affinity IgE receptor because of its implication in the allergic response, it has become clear that mast cells can be activated by multiple types of receptors initiating an intense molecular crosstalk between receptors and signaling pathways that can either synergize, antagonize and in some cases produce new types of responses. Mast cells can indeed react with an astounding diverse array of cellular responses that sometimes are engaged selectively. This Research Topic will focus on selected articles that shed some new light on the molecular mechanisms of mast cell activation, the possible crosstalk between signaling pathways and the ensuing cellular responses that allow mast cells to act as cellular sensors in tissues.

IGE Receptor (FceRI) Function in Mast Cells and Basophils

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Publisher :
ISBN 13 : 9781570593802
Total Pages : 292 pages
Book Rating : 4.5/5 (938 download)

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Book Synopsis IGE Receptor (FceRI) Function in Mast Cells and Basophils by : Majed M. Hamawy

Download or read book IGE Receptor (FceRI) Function in Mast Cells and Basophils written by Majed M. Hamawy and published by . This book was released on 1997-01-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: