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Sex Differences In Immunometabolism Prophylaxis And Therapy
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Book Synopsis Sex differences in immunometabolism, prophylaxis and therapy by : Milica Vujičić
Download or read book Sex differences in immunometabolism, prophylaxis and therapy written by Milica Vujičić and published by Frontiers Media SA. This book was released on 2023-09-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune system function and metabolism are profoundly intertwined on a whole-body and cellular level. This is reflected in both homeostatic processes during growth and development and in pathological states. For instance, chronic inflammation in adipose tissue is a strong predictor of insulin resistance and metabolic syndrome, overall increasing risk for type 2 diabetes and associated co-morbidities in obese individuals. Simultaneously, increased visceral adiposity is linked with a delayed or deficient immune response to infection. On the cellular level, immune cell phenotype is intimately connected with metabolic status. In states of high energy demand immune cells rely on glycolysis for producing ATP, while oxidative phosphorylation is the preferred energy source in resting and regulatory states.
Download or read book Immunometabolism written by Suresh Mishra and published by Humana. This book was released on 2021-09-02 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book showcases the tremendous effort and progress made in developing techniques and protocols for the study of immunometabolism, and in utilizing recent technological advances for probing and manipulating adipose and immune cells, and subsequently, their functions and immunometabolic consequences. Written by experts in the field, many chapters use macrophages as a model immune cell type, due to their prominence in the innate immune system and the exhaustive study of their traits. Protocols using adipocytes, dendritic cells, and T cells as model cell lines, as well as measurement of glucose metabolism at the systemic level, have also been included. Written for the highly successful Methods in Molecular Biology book series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immunometabolism: Methods and Protocols serves as a vital guide for researchers working at the important interface of immunology and metabolism.
Book Synopsis The Roles of Lipids in Immunometabolism: The Crosstalk Between Lipid Metabolisms and Inflammation by : Yiliang Chen
Download or read book The Roles of Lipids in Immunometabolism: The Crosstalk Between Lipid Metabolisms and Inflammation written by Yiliang Chen and published by Frontiers Media SA. This book was released on 2022-07-18 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunometabolism, Atherosclerosis and Metabolic Diseases by : Xuewei Zhu
Download or read book Immunometabolism, Atherosclerosis and Metabolic Diseases written by Xuewei Zhu and published by Frontiers Media SA. This book was released on 2022-03-29 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Women in Biomaterials Science 2023 by : Silviya Petrova Zustiak
Download or read book Women in Biomaterials Science 2023 written by Silviya Petrova Zustiak and published by Frontiers Media SA. This book was released on 2024-09-11 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are pleased to announce the launch of the 2nd Edition of "Women in Science: Biomaterials Science" Research Topic in Frontiers in Biomaterials Science. At present, less than 30% of all researchers worldwide are women and similar ratios are seen in the science community, particularly in the US. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Book Synopsis Gender Differences in Metabolism by : Mark Tarnopolsky
Download or read book Gender Differences in Metabolism written by Mark Tarnopolsky and published by CRC Press. This book was released on 1998-11-23 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gender Differences in Metabolism: Practical and Nutritional Implications is the first book to successfully integrate nutritional science, exercise physiology/medicine, and metabolism. This volume explores recent scientific evidence that male and female athletes exhibit different metabolic responses and, therefore, differ in their nutritional needs and advice. Anyone interested in good health, exercise, and nutrition will find this book a valuable resource.
Book Synopsis Systemic Autoimmunity by : P. E. Bigazzi
Download or read book Systemic Autoimmunity written by P. E. Bigazzi and published by CRC Press. This book was released on 1991-08-30 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surveys the biotechnologically influenced advances in the understanding of systemic autoimmune disorders, highlighting recent research using cell biology and biochemistry, the cloning of immune cells, recombinant DNA, and molecular genetics. Among the topics are the role of complement in inflammatio
Download or read book Buruli Ulcer written by Gerd Pluschke and published by Springer. This book was released on 2019-04-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Book Synopsis Immune Checkpoint Inhibitors in Cancer by : Fumito Ito
Download or read book Immune Checkpoint Inhibitors in Cancer written by Fumito Ito and published by Elsevier Health Sciences. This book was released on 2018-09-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.
Book Synopsis Sex Bias in Autoimmunity: From Animal Models to Clinical Research and Applications by : Coziana Ciurtin
Download or read book Sex Bias in Autoimmunity: From Animal Models to Clinical Research and Applications written by Coziana Ciurtin and published by Frontiers Media SA. This book was released on 2023-01-17 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune diseases are characterized by an abnormal and self-directed immune response leading to damage and dysfunction of multiple organs and tissues. Most autoimmune diseases are recognized as affecting disproportionately more women than men, suggesting a crucial role of sex hormones in modulating immune responses, with estrogens being postulated as enhancing autoimmunity and androgens playing a protective role. It is also widely acknowledged that there is an overwhelming male bias in non-human (animal) studies of autoimmune diseases, while studies of both sexes in human research frequently fail to analyze results by sex. Underrepresentation of females in animal models of autoimmune disease is often justified by their intrinsic variability during the reproductive period, compromising the understanding of impact of the female sex chromosome and hormones on immune system functions leading to the high prevalence of autoimmune conditions. This Research Topic will highlight the most recent advances in understanding the possible mechanisms for sex-specific differences in autoimmunity, with a specific focus on pre-clinical animal and human models of autoimmune inflammation, as well as on the most common sex specific differences in autoimmune diseases. The topic will emphasize advances in research exploring sex determinants in autoimmune rheumatic diseases such as systemic lupus erythematosus, rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, Sjӧgren's syndrome and further diseases such as inflammatory bowel disease, autoimmune hepatitis, multiple sclerosis, psoriasis, asthma and more. The present Research Topic will include both full length and short research communications, as well as perspective and review articles addressing various aspects of sex biased differences in pathogenesis, age at disease onset, clinical manifestations, disease course, treatment response, associated co-morbidities and overall survival across different autoimmune diseases.
Book Synopsis Essential Aspects of Immunometabolism in Health and Disease by : Niels Olsen Saraiva Camara
Download or read book Essential Aspects of Immunometabolism in Health and Disease written by Niels Olsen Saraiva Camara and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
Book Synopsis Neural Regulation of Metabolism by : Qi Wu
Download or read book Neural Regulation of Metabolism written by Qi Wu and published by Springer. This book was released on 2018-11-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
Book Synopsis Handbook of Sepsis by : W. Joost Wiersinga
Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Book Synopsis Immune Function in Sport and Exercise by : Michael Gleeson
Download or read book Immune Function in Sport and Exercise written by Michael Gleeson and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the risk of immunodepression and infection in athletes. Further chapters explore different ways of measuring immune function, as well as the effects of heavy training on innate and specific (acquired) immunity, exercise in environmental extremes, and nutrition. Connections between exercise, infection risk, and immune function in special populations (elderly, obese, diabetic and HIV patients) are also addressed. Authored by a team of highly experienced experts. The "J-shaped" relationship between exercise load and infection risk is described, backed by current research and evidence. Components of the immune system and normal immune function are explained in detail, as well as methods for measuring immune function. The impact of acute and chronic psychological stress on immune function is presented, along with suggestions for minimizing the risk of immunodepression and infection in athletes. The effects of heavy training, exercise in environmental extremes, and nutrition are discussed with regard to their impact on innate and specific (acquired) immunity. Immune function in special populations (elderly, obese, diabetic and HIV patients) is also addressed, exploring links between exercise and infection risk in these groups. Evidence-based coverage includes a list of references in each chapter, as well as suggestions for further reading that direct readers to important texts and review articles. Information is presented in an easily accessible format, following a logical progression of material. LEach chapter begins with a list of learning objectives and ends with a list of key points to reinforce learning. A glossary at the end of the book defines all key terms and abbreviations.
Book Synopsis Primary Immunodeficiency Disorders by : Amos Etzioni
Download or read book Primary Immunodeficiency Disorders written by Amos Etzioni and published by Academic Press. This book was released on 2014-09-13 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established Provides stimulating discussions on developing new medical therapiesHighlights the importance of studying humans to understand mechanisms of disease that affect humans
Book Synopsis Sex Hormones, Exercise and Women by : Anthony C. Hackney
Download or read book Sex Hormones, Exercise and Women written by Anthony C. Hackney and published by Springer Nature. This book was released on 2023-06-05 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a revised and expanded second edition including seven brand new chapters, this book compiles and synthesizes the latest research and clinical evidence regarding the intricate relationship between sex hormones and the physical activity level and overall health of the female endocrine system across the lifespan. Expert authors from around the world discuss in detail the impact of sex hormones on energy metabolism, cardiorespiratory system, nervous system, and musculoskeletal health, as well as environmental and psychological factors affecting exercise and sexual health. Considerations of the hormonal and physiological changes to the menstrual cycle and in menopause due to exercise receive chapters of their own. New to this edition are discussions of pregnancy, menopause, aerobic endurance training, the transgender athlete, sports performance, and the future of sports and exercise science relating to the active female. Covering a hot topic in sports medicine and science, Sex Hormones, Exercise and Women, Second Edition will be of interest to researchers, clinicians, exercise scientists, and residents and fellows in these areas.
Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel
Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
