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Sensibilisation Centrale Au Cours Des Rhumatismes Inflammatoires
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Book Synopsis Sensibilisation centrale au cours des rhumatismes inflammatoires by : Arielle Simunek
Download or read book Sensibilisation centrale au cours des rhumatismes inflammatoires written by Arielle Simunek and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objectif : Les patients atteints de rhumatisme inflammatoire chronique (RIC) peuvent présenter une sensibilisation centrale (SC), de par la chronicité de leur douleur. L'inventaire de sensibilisation centrale (ISC) est un questionnaire validé, qui, au-delà de 40/100, évoque une SC. Nous évaluons le caractère prédictif de réponse thérapeutique d'un ISC positif à un premier traitement par anti-TNF dans une cohorte de 100 RIC à 3 mois du début du traitement. Méthode : étude observationnelle, prospective, contrôlée, bi-centrique incluant 100 patients (présentant un RIC actif, naïf de biothérapie) et 100 témoins. Évaluation de l'ISC avant et à 3 mois de l'initiation de l'anti-TNF. Résultats : un ISC positif est retrouvé chez 60% des patients contre 9% des témoins avant initiation de l'anti-TNF. A 3 mois, 47 patients (62,7%) répondent au critère de bonne réponse thérapeutique défini par une amélioration du DAS 28 > 1,2 ou de l'ASDAS >1,1. Le calcul de l'odd ratio évaluant la relation entre un ISC > 40/100 et l'efficacité du traitement mesurée sur l'amélioration du DAS 28 ou de l'ASDAS retrouve une valeur significative de 0,28 (IC 95% 0,098 - 0,83). De plus, l'âge et l'activité du rhumatisme sont des facteurs prédictifs respectivement de bonne et mauvaise réponse thérapeutique. Enfin, l'ISC est corrélé à l'ensemble des questionnaires algofonctionnels mais également à la CPM. Conclusion : Chez les patients atteints de RIC, un ISC supérieur à 40/100 est prédictif de moins bonne réponse thérapeutique à 3 mois de l'introduction d'un traitement par anti-TNF. La sensibilisation centrale gagne donc à être dépistée et prise en charge afin d'améliorer la qualité de vie des patients.
Book Synopsis On the Use of the Moxa by : Dominique Jean baron Larrey
Download or read book On the Use of the Moxa written by Dominique Jean baron Larrey and published by . This book was released on 1822 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Chronopharmacology by : Alain Reinberg
Download or read book Clinical Chronopharmacology written by Alain Reinberg and published by CRC Press. This book was released on 1990-07 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Periodical and predictable changes in biological susceptibility and response to a large variety of chemical agents, including drugs and food, have been documented since the early 1970s. This book provides a survey of clinically-documented research in chronopharmacology.
Book Synopsis Biological Rhythm Research by : A. Sollberger
Download or read book Biological Rhythm Research written by A. Sollberger and published by . This book was released on 1965 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Introduction to Differential Manifolds by : Jacques Lafontaine
Download or read book An Introduction to Differential Manifolds written by Jacques Lafontaine and published by Springer. This book was released on 2015-07-29 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to differential manifolds. It gives solid preliminaries for more advanced topics: Riemannian manifolds, differential topology, Lie theory. It presupposes little background: the reader is only expected to master basic differential calculus, and a little point-set topology. The book covers the main topics of differential geometry: manifolds, tangent space, vector fields, differential forms, Lie groups, and a few more sophisticated topics such as de Rham cohomology, degree theory and the Gauss-Bonnet theorem for surfaces. Its ambition is to give solid foundations. In particular, the introduction of “abstract” notions such as manifolds or differential forms is motivated via questions and examples from mathematics or theoretical physics. More than 150 exercises, some of them easy and classical, some others more sophisticated, will help the beginner as well as the more expert reader. Solutions are provided for most of them. The book should be of interest to various readers: undergraduate and graduate students for a first contact to differential manifolds, mathematicians from other fields and physicists who wish to acquire some feeling about this beautiful theory. The original French text Introduction aux variétés différentielles has been a best-seller in its category in France for many years. Jacques Lafontaine was successively assistant Professor at Paris Diderot University and Professor at the University of Montpellier, where he is presently emeritus. His main research interests are Riemannian and pseudo-Riemannian geometry, including some aspects of mathematical relativity. Besides his personal research articles, he was involved in several textbooks and research monographs.
Book Synopsis Minimum Competence in Scientific English by : Susan Blattès
Download or read book Minimum Competence in Scientific English written by Susan Blattès and published by . This book was released on 1991 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Le présent ouvrage répond à un objectif précis : être un outil efficace pour ceux qui sont confrontés à des textes en anglais scientifique. Minimum Competence in Scientific English suppose, pour ses utilisateurs, des prérequis de niveau baccalauréat. Il peut être utilisé en autoformation. Les étudiants scientifiques sont évidemment les premiers concernés, mais l'expérience a démontré que les chercheurs, les ingénieurs, les enseignants, les managers, confrontés aux subtilités de l'anglais scientifique écrit, étaient demandeurs de tels ouvrages.
Book Synopsis Current List of Medical Literature by :
Download or read book Current List of Medical Literature written by and published by . This book was released on 1958 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Book Synopsis Endocrine Rhythms by : Dorothy T. Krieger
Download or read book Endocrine Rhythms written by Dorothy T. Krieger and published by . This book was released on 1979 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Current List of Medical Literature by :
Download or read book Current List of Medical Literature written by and published by . This book was released on 1958 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of physiology by : William Ferguson Hamilton
Download or read book Handbook of physiology written by William Ferguson Hamilton and published by . This book was released on 1963 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
