Pharmaceuticals, Corporate Crime and Public Health

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Author :
Publisher : Edward Elgar Publishing
ISBN 13 : 1783471107
Total Pages : 419 pages
Book Rating : 4.7/5 (834 download)

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Book Synopsis Pharmaceuticals, Corporate Crime and Public Health by : Graham Dukes

Download or read book Pharmaceuticals, Corporate Crime and Public Health written by Graham Dukes and published by Edward Elgar Publishing. This book was released on 2014-06-27 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry exists to serve the community, but over the years it has engaged massively in corporate crime, with the public footing the bill. This readable study by experts in medicine, law, criminology and public health documents the pr

Crohn's Disease and Ulcerative Colitis

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Author :
Publisher : Springer
ISBN 13 : 3319337033
Total Pages : 671 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Crohn's Disease and Ulcerative Colitis by : Daniel C. Baumgart

Download or read book Crohn's Disease and Ulcerative Colitis written by Daniel C. Baumgart and published by Springer. This book was released on 2017-03-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.

Innovations for Next-Generation Antibody-Drug Conjugates

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Author :
Publisher : Springer
ISBN 13 : 3319781545
Total Pages : 358 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Innovations for Next-Generation Antibody-Drug Conjugates by : Marc Damelin

Download or read book Innovations for Next-Generation Antibody-Drug Conjugates written by Marc Damelin and published by Springer. This book was released on 2018-05-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.

Pharmaceutical R&D

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Author :
Publisher : DIANE Publishing
ISBN 13 : 9780788104688
Total Pages : 380 pages
Book Rating : 4.1/5 (46 download)

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Book Synopsis Pharmaceutical R&D by :

Download or read book Pharmaceutical R&D written by and published by DIANE Publishing. This book was released on 1993 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analyzes the costs, risks, and economic rewards of pharmaceutical R&D and the impact of public policy on both costs and returns. Examines the rapid increase in pharmaceutical R&D that began in the 1980s in the light of trends in science, technology, drug discovery, and health insurance coverage; Government regulation; product liability; market competition; Federal tax policy; and Federal support of prescription drug research. 12 appendices, including a glossary of terms.

Molecular Therapies of Cancer

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Publisher : Springer
ISBN 13 : 3319132784
Total Pages : 486 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Molecular Therapies of Cancer by : Georg F. Weber

Download or read book Molecular Therapies of Cancer written by Georg F. Weber and published by Springer. This book was released on 2015-07-22 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.

Industrial Pharmaceutical Biotechnology

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Author :
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Industrial Pharmaceutical Biotechnology by : Heinrich Klefenz

Download or read book Industrial Pharmaceutical Biotechnology written by Heinrich Klefenz and published by Wiley-VCH. This book was released on 2002-04-22 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Urologic Oncology

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Author :
Publisher : Springer
ISBN 13 : 9783319426228
Total Pages : 870 pages
Book Rating : 4.4/5 (262 download)

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Book Synopsis Urologic Oncology by : Axel S. Merseburger

Download or read book Urologic Oncology written by Axel S. Merseburger and published by Springer. This book was released on 2019-08-21 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and timely textbook covers all aspects of the evidence-based management of genitourinary cancers and explains the fundamental principles underlying the available diagnostic and treatment approaches, including chemotherapy, radiotherapy, immunotherapy, and surgery. For each type of cancer – prostate, bladder, renal, testicular, and penile, plus rare urologic malignancies – clinical presentation, diagnosis, and treatment strategies are described in detail and information is provided on etiology, epidemiology, risk factors, and pathology, including TNM classification. Careful attention is also devoted to the complications that may be encountered when treating urologic malignancies and to the management of these complications. The text is complemented by the inclusion of numerous high-definition photographs and illustrations. Urologic Oncology will be a valuable reference and source of guidance for all oncologists, urologists and practitioners in related disciplines who treat patients with urologic cancers.

Acneiform Eruptions in Dermatology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461483441
Total Pages : 405 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Acneiform Eruptions in Dermatology by : Joshua A. Zeichner

Download or read book Acneiform Eruptions in Dermatology written by Joshua A. Zeichner and published by Springer Science & Business Media. This book was released on 2013-11-08 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermatologists commonly treat acne, which affects 40 to 50 million Americans each year and about 85 percent of all patients at some point in their lives. Dermatologists, primary care doctors, and pediatricians see these patients every day in practice. It is important to treat the skin effectively not only to reduce the risk of physical scarring, but also to address the negative psychosocial impact this disease carries. Improving the skin can improve self-confidence, interpersonal relationships, and performance in school or at work. Acneiform Eruptions in Dermatology is a practical, full-color guide to the differential diagnosis of acne vulgaris and the treatment of acne-like conditions. It is organized into sections by subtype of condition (e.g., infections, genetic syndromes, medication-caused) and includes a section of variants of acne that may be misdiagnosed. Within the sections, individual chapters discuss each variant of the condition and begin with a helpful bulleted summary of its defining clinical features. Extensive color clinical images appear throughout the book.

Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

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Author :
Publisher : CRC Press
ISBN 13 : 1420004131
Total Pages : 474 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems by : Ashok Katdare

Download or read book Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems written by Ashok Katdare and published by CRC Press. This book was released on 2006-07-28 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.

Antibiotic Discovery and Development

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461414008
Total Pages : 1119 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Antibiotic Discovery and Development by : Thomas J. Dougherty

Download or read book Antibiotic Discovery and Development written by Thomas J. Dougherty and published by Springer Science & Business Media. This book was released on 2011-12-18 with total page 1119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.

Practical Approaches to Risk Minimisation for Medicinal Products

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Author :
Publisher :
ISBN 13 : 9789290360841
Total Pages : 0 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis Practical Approaches to Risk Minimisation for Medicinal Products by : World Health Organization

Download or read book Practical Approaches to Risk Minimisation for Medicinal Products written by World Health Organization and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk management of medicines is a wide and rapidly evolving concept and practice, following a medicine throughout its lifecycle, from first administration in humans through clinical studies and then marketing in the patient population at large. Previous reports from CIOMS I - VIII provided practical guidance in some essential components of risk management such as terminology and reporting of adverse drug reactions, management of safety information from clinical trials, and safety signal detection. Beyond the detection, identification, and characterization of risk, "risk minimization" is used as an umbrella term for the prevention or mitigation of an undesirable outcome. Risk management always includes tools for "routine risk minimization" such as product information, the format depending on the jurisdiction, to inform the patient and the prescriber, all of which serve to prevent or mitigate adverse effects. Until this current CIOMS IX document, limited guidance has been available on how to determine which risks need "additional risk minimization," select the appropriate tools, apply and implement such tools globally and locally, and measure if they are effective and valuable. Included in the report is a CIOMS framework for the evaluation of effectiveness of risk minimization, a discussion of future trends and developments, an annex specifically addressing vaccines, and examples from real life.

Hepatitis Prevention and Treatment

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783764359560
Total Pages : 262 pages
Book Rating : 4.3/5 (595 download)

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Book Synopsis Hepatitis Prevention and Treatment by : Joseph M. Colacino

Download or read book Hepatitis Prevention and Treatment written by Joseph M. Colacino and published by Springer Science & Business Media. This book was released on 2004-10-25 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development. This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field.

Bridging Islands

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199268800
Total Pages : 415 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Bridging Islands by : Robert Kneller

Download or read book Bridging Islands written by Robert Kneller and published by Oxford University Press. This book was released on 2007-08-23 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging Islands is a detailed examination of the key role of venture companies in national technical and economic success, contrasting the industrial and social organization of the world's two largest economies, the US and Japan. The author argues that national policy on venture companies is of paramount importance to their economic growth.

The War on Cancer

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402036175
Total Pages : 225 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The War on Cancer by : Guy B. Faguet

Download or read book The War on Cancer written by Guy B. Faguet and published by Springer Science & Business Media. This book was released on 2008-11-23 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows that, contrary to frequent announcements of breakthroughs, our current cancer control model cannot eradicate most cancers and the reasons why. Significantly, this book also delineates a way forward via a shift from the discredited cell-kill approach of the past to an integrated, evidence-driven cancer control paradigm based on prevention, early diagnosis, and pharmacogenomics. The author's views are based on data published in mainstream scientific journals and other reliable references, 432 of which are cited.

A Door Into Ocean

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Author :
Publisher : Orb Books
ISBN 13 : 1429963654
Total Pages : 418 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis A Door Into Ocean by : Joan Slonczewski

Download or read book A Door Into Ocean written by Joan Slonczewski and published by Orb Books. This book was released on 2000-10-13 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joan Slonczewski's A Door into Ocean is the novel upon which the author's reputation as an important SF writer principally rests. A ground-breaking work both of feminist SF and of world-building hard SF, it concerns the Sharers of Shora, a nation of women on a distant moon in the far future who are pacifists, highly advanced in biological sciences, and who reproduce by parthenogenesis--there are no males--and tells of the conflicts that erupt when a neighboring civilization decides to develop their ocean world, and send in an army. At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.

Time

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Publisher :
ISBN 13 :
Total Pages : 862 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Time by : Briton Hadden

Download or read book Time written by Briton Hadden and published by . This book was released on 1994 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ferret Medicine and Surgery

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Author :
Publisher : CRC Press
ISBN 13 : 1315354292
Total Pages : 1239 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Ferret Medicine and Surgery by : Cathy Johnson-Delaney

Download or read book Ferret Medicine and Surgery written by Cathy Johnson-Delaney and published by CRC Press. This book was released on 2016-10-14 with total page 1239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text is currently the most up-to-date book on ferret medicine and as such, would be an important addition to the library of veterinary practices seeing these lively, curious and fun-loving pets. Aidan Raftery, Veterinary Record 17 March 2018 Ferrets are becoming increasingly popular as pets, rivalling rabbits as the third most favoured domestic pet after dogs and cats. Ferret Medicine and Surgery discusses the veterinary aspects of this incredible little creature. The book covers ferret medicine and common surgeries, providing a comprehensive reference for the veterinary practitioner. Each chapter of disorders is designed to be inclusive and includes cross references to other chapters throughout as well as some highlights of anatomy and physiology as a review. The format allows easy access to information providing answers to problems that arise in practice. Thoroughly illustrated with high-quality photographs and line drawings, the book is designed to provide quick, concise information of immediate use to the practitioner.