Roles Of Sleep Disruption And Circadian Rhythm Alterations On Neurodegeneration And Alzheimers Disease

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Circadian Rhythm Sleep-Wake Disorders

Author : R. Robert Auger
Publisher : Springer Nature
ISBN 13 : 3030438031
Total Pages : 251 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Circadian Rhythm Sleep-Wake Disorders by : R. Robert Auger

Download or read book Circadian Rhythm Sleep-Wake Disorders written by R. Robert Auger and published by Springer Nature. This book was released on 2020-05-26 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book resolves to bridge the communication gap between research and clinical practice for circadian rhythm sleep-wake disorders. Beginning with a scientific background on biological timekeeping, opening chapters describe the crucial nature of maintaining delicate temporal organization of physiological and molecular events within the body. Following this are discussions on circadian physiology and methods of circadian assessments. Subsequent chapters then relay comprehensive information regarding the International Classification of Sleep Disorders-defined circadian rhythm sleep-wake disorders (CRSWDs), specifically discussing etiology and epidemiology, but focusing on evidence-based treatment data. Concluding discussions provide guidance for the application of light therapy and discuss future roles for optimized lighting environments. Nuanced and market-demanded, Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators is an invaluable resource for Sleep Medicine clinicians, circadian researchers, and other interested parties.

Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer’s Disease

Author : Marilyn J. Duncan
Publisher : Frontiers Media SA
ISBN 13 : 2889715388
Total Pages : 136 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer’s Disease by : Marilyn J. Duncan

Download or read book Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer’s Disease written by Marilyn J. Duncan and published by Frontiers Media SA. This book was released on 2021-10-22 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sleep Disorders and Sleep Deprivation

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101115
Total Pages : 425 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine

Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Redox Proteomics

Author : Isabella Dalle-Donne
Publisher : John Wiley & Sons
ISBN 13 : 0471973114
Total Pages : 978 pages
Book Rating : 4.4/5 (719 download)

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Book Synopsis Redox Proteomics by : Isabella Dalle-Donne

Download or read book Redox Proteomics written by Isabella Dalle-Donne and published by John Wiley & Sons. This book was released on 2006-08-11 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methodology and applications of redox proteomics The relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated diseases. This collection brings together, in one comprehensive volume, a broad array of information and insights into normal and altered physiology, molecular mechanisms of disease states, and new applications of the rapidly evolving techniques of proteomics. Written by some of the finest investigators in this area, Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases examines the key topics of redox proteomics and redox control of cellular function, including: * The role of oxidized proteins in various disorders * Pioneering studies on the development of redox proteomics * Analytical methodologies for identification and structural characterization of proteins affected by oxidative/nitrosative modifications * The response and regulation of protein oxidation in different cell types * The pathological implications of protein oxidation for conditions, including asthma, cardiovascular disease, diabetes, preeclampsia, and Alzheimer's disease Distinguished by its in-depth discussions, balanced methodological approach, and emphasis on medical applications and diagnosis development, Redox Proteomics is a rich resource for all professionals with an interest in proteomics, cellular physiology and its alterations in disease states, and related fields.

The Behavioral Neurology of Dementia

Author : Bruce L. Miller
Publisher : Cambridge University Press
ISBN 13 : 1107077206
Total Pages : 491 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis The Behavioral Neurology of Dementia by : Bruce L. Miller

Download or read book The Behavioral Neurology of Dementia written by Bruce L. Miller and published by Cambridge University Press. This book was released on 2016-11-17 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distils the most valuable discoveries in dementia research into clear, insightful chapters written by international experts.

The Circadian System in Parkinson's Disease

Author : Karim Fifel
Publisher :
ISBN 13 : 9783659845499
Total Pages : 180 pages
Book Rating : 4.8/5 (454 download)

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Book Synopsis The Circadian System in Parkinson's Disease by : Karim Fifel

Download or read book The Circadian System in Parkinson's Disease written by Karim Fifel and published by . This book was released on 2017-06-20 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chronotherapeutics

Author : P. H. Redfern
Publisher : Pharmaceutical Press
ISBN 13 : 9780853694885
Total Pages : 456 pages
Book Rating : 4.6/5 (948 download)

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Book Synopsis Chronotherapeutics by : P. H. Redfern

Download or read book Chronotherapeutics written by P. H. Redfern and published by Pharmaceutical Press. This book was released on 2003 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: In nature, many physical processes are governed by the passage of time. The study of these processes - chronobiology - reveals rhythmic patterns which may be yearly, monthly, daily or more frequent. Novel drug delivery systems are currently being delivered that will release varying quantities of a drug at optimum times to coincide with these rhythmic patterns.Chronotherapeutics considers the pharmaceutical and therapeutic implications associated with biological clocks. The book presents a comprehensive discussion of specific diseases that are time dependent, and the drugs and new drug formulations that can be used as treatments.Written by leading international experts in the field, Chronotherapeutics provides up-to-date information on chronobiology for non-chronobiologists in pharmaceutical and medical sciences. Peter Redfern is Professor of Pharmacology at the University of Bath, UK.

Sleep Neurology

Author : Lourdes M. DelRosso
Publisher : Springer Nature
ISBN 13 : 3030543595
Total Pages : 309 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Sleep Neurology by : Lourdes M. DelRosso

Download or read book Sleep Neurology written by Lourdes M. DelRosso and published by Springer Nature. This book was released on 2020-11-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical text provides knowledge of the basic neuroscience of sleep and sleep disorders as they interrelate with various neurologic conditions. Chapters in the first section cover neural networks involved in normal sleep processes, including dreams and memory. Also discussed are how these neural networks interact in various sleep stages and sleep disorders, such as sleep related movement disorders. The book's second section explores the pathophysiology of sleep disorders in the spectrum of neurologic conditions in both adults and children. This includes sleep changes in patients with dementia, seizures, headaches, and stroke, and other common neurologic disorders. Sleep Neurology fills an important gap in the sleep medicine literature by providing the underpinnings of sleep disorders and will be of great value to students, residents, and clinicians.

Circadian Clock in Brain Health and Disease

Author : Olivia Engmann
Publisher : Springer Nature
ISBN 13 : 3030811476
Total Pages : 193 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Circadian Clock in Brain Health and Disease by : Olivia Engmann

Download or read book Circadian Clock in Brain Health and Disease written by Olivia Engmann and published by Springer Nature. This book was released on 2021-11-13 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in the field review how circadian rhythms impact the brain. An essential function of mammalian life is the exploitation of the regularities provided by the 24-hour cycle of day and night. The development and evolution of circadian clock mechanisms have allowed us to optimally adapt our behavior and physiology to the external world. Not surprisingly, a growing body of evidence links the disruption of circadian rhythms by genetic, lifestyle and environmental factors to illnesses of the brain. In the first section of the book, readers will learn about the molecular and anatomic architecture of circadian function in mammals. The ways in which environmental disruptions and misalignments can influence such mechanisms and therefore impair brain function and health status are also addressed. In the second part, the focus shifts to those brain regions responsible for brain function and the body-wide regulation of circadian function. Amongst others, special attention is paid to the role of astrocytes and the brain’s reward and hyprocretin / orexin systems. The book concludes with an extensive discussion on the consequences of circadian rhythm dysfunction. Several chapters present the latest findings on Attention Deficit Hyperactivity Disorder, schizophrenia, autism spectrum disorder, drug abuse and mood disorders. Written by auhorities in the field, the book provides a state-of-the-art review of the latest findings on circadian clocks in the brain and highlights their potentially far-reaching impacts on our health and well-being. As such, it is essential reading for all neuroscientists and clinicians seeking to understand the intricate connections between circadian rhythms and brain health and illness.

The Orexin System. Basic Science and Role in Sleep Pathology

Author : M.A. Steiner
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068446
Total Pages : 165 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis The Orexin System. Basic Science and Role in Sleep Pathology by : M.A. Steiner

Download or read book The Orexin System. Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Neuroimaging of Sleep and Sleep Disorders

Author : Eric Nofzinger
Publisher : Cambridge University Press
ISBN 13 : 1107018633
Total Pages : 445 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neuroimaging of Sleep and Sleep Disorders by : Eric Nofzinger

Download or read book Neuroimaging of Sleep and Sleep Disorders written by Eric Nofzinger and published by Cambridge University Press. This book was released on 2013-03-07 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.

Preventing Cognitive Decline and Dementia

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459591
Total Pages : 181 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Preventing Cognitive Decline and Dementia by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Sleep Deprivation, Stimulant Medications, and Cognition

Author : Nancy J. Wesensten
Publisher : Cambridge University Press
ISBN 13 : 1107004098
Total Pages : 287 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Sleep Deprivation, Stimulant Medications, and Cognition by : Nancy J. Wesensten

Download or read book Sleep Deprivation, Stimulant Medications, and Cognition written by Nancy J. Wesensten and published by Cambridge University Press. This book was released on 2012-08-23 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a critical review of stimulant medication literature regarding stimulant efficacy for restoring/maintaining cognition during sleep loss.

Management of Patients with Dementia

Author : Kristian Steen Frederiksen
Publisher : Springer Nature
ISBN 13 : 3030779041
Total Pages : 437 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Management of Patients with Dementia by : Kristian Steen Frederiksen

Download or read book Management of Patients with Dementia written by Kristian Steen Frederiksen and published by Springer Nature. This book was released on 2021-07-26 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overall introduction to the medical management of dementia with chapters dedicated to specific topics such as pain, epilepsy, vascular risk factors in dementia and review of medication, which are often not addressed in books on the subject, and thereby filling a gap in the field. Chapters are supplemented with cases to highlight key concepts and treatment approaches, and to provide the reader with the possibility to reflect on management options and the readers ́ own current practice. This book is aimed at clinicians of different specialties (mainly neurology, psychiatry, geriatric medicine and general practice/family medicine) who manage patients with dementia on a regular basis, and thus provides useful guidance to be used in the clinic.

Sleep-Wake Neurobiology and Pharmacology

Author : Hans-Peter Landolt
Publisher : Springer Nature
ISBN 13 : 3030112721
Total Pages : 473 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Sleep-Wake Neurobiology and Pharmacology by : Hans-Peter Landolt

Download or read book Sleep-Wake Neurobiology and Pharmacology written by Hans-Peter Landolt and published by Springer Nature. This book was released on 2019-09-03 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com

Psychiatric Care of the Medical Patient

Author : Barry S. Fogel
Publisher : Oxford University Press
ISBN 13 : 0190226293
Total Pages : 1813 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Psychiatric Care of the Medical Patient by : Barry S. Fogel

Download or read book Psychiatric Care of the Medical Patient written by Barry S. Fogel and published by Oxford University Press. This book was released on 2015-05-28 with total page 1813 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of Psychiatric Care of the Medical Patient brings a classic reference text into the twenty-first century. It combines critical scholarship with the voice of expert clinicians who work at the interface of psychiatry with medical specialties. It is meant to be read for pleasure as well as consulted as a reference. The editors have worked with the authors to bring a consistent perspective to the book - one that sees the medical psychiatrist as an agent for bringing a more comprehensive perspective to medical care. Even seasoned and knowledgeable practitioners will find much that is new to them in this book. The volume covers topics in depth that other books in the field may not cover at all, such as the use of herbal and nutritional therapies for medical-psychiatric symptoms and syndromes, and the choice of questionnaires to supplement history-taking. It looks at old topics in a new way: The chapter on the physical examination applies psychometric considerations to the Babinski sign, describes the method and application of quantitative bedside olfactory testing, and discusses smartphone apps to improve the sensitivity of the examination. Psychiatric Care of the Medical Patient, 3rd Edition provides concepts and information to facilitate the dialogue between psychiatrists and general medical specialists - minimizing psychiatric jargon and speaking in the common language of caring and curious physicians.

Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Author : Agustín Ibáñez
Publisher : Frontiers Media SA
ISBN 13 : 2889454940
Total Pages : 217 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America by : Agustín Ibáñez

Download or read book Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America written by Agustín Ibáñez and published by Frontiers Media SA. This book was released on 2018-06-21 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.