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Role Of The Choroid Plexus In Health And Disease
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Book Synopsis Role of the Choroid Plexus in Health and Disease by : Jeppe Praetorius
Download or read book Role of the Choroid Plexus in Health and Disease written by Jeppe Praetorius and published by Springer Nature. This book was released on 2020-04-17 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue. Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in the choroid plexus is not only important for the readers’ understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.
Book Synopsis The Choroid Plexus in Health and Disease by : Martin G. Netsky
Download or read book The Choroid Plexus in Health and Disease written by Martin G. Netsky and published by Butterworth-Heinemann. This book was released on 2013-09-24 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Choroid Plexus in Health and Disease is a collection of data and information elucidating the normal structure and function, and the clinical disorders of the choroid plexus in relation to embryology, anatomy, chemistry, and physiology. The book contains articles that discuss topics on the origin of choroid plexus and ependyma; normal structure of choroid plexus; physiology of the choroid plexus; heterotopic choroid plexus and ependyma; traumatic disorders and their effect on choroid plexus and ependyma; and metastatic tumor in the choroid plexus. Physiologists, neurologists, anatomists, teachers, and students in the medical field will find the book invaluable.
Book Synopsis Role of the Choroid Plexus in Health and Disease by :
Download or read book Role of the Choroid Plexus in Health and Disease written by and published by . This book was released on 2020 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue. Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in the choroid plexus is not only important for the readers' understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.
Book Synopsis The Blood-Cerebrospinal Fluid Barrier by : Wei Zheng
Download or read book The Blood-Cerebrospinal Fluid Barrier written by Wei Zheng and published by CRC Press. This book was released on 2005-03-30 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.
Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Book Synopsis The Choroid Plexus in Health and Disease by : Britta Engelhardt
Download or read book The Choroid Plexus in Health and Disease written by Britta Engelhardt and published by . This book was released on 2001 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Neuronal Environment by : Wolfgang Walz
Download or read book The Neuronal Environment written by Wolfgang Walz and published by Springer Science & Business Media. This book was released on 2001-12-26 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in blood-brain barrier function, and inflammation and the neuroimmune system. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the only information processing system in the brain.
Book Synopsis The choroid plexus in health and disease by : Martin George Netzky
Download or read book The choroid plexus in health and disease written by Martin George Netzky and published by . This book was released on 1975 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pediatric Hydrocephalus by : G. Cinalli
Download or read book Pediatric Hydrocephalus written by G. Cinalli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last ten years the pediatric neurosurgeon has witnessed a real revolution in the diagnosis and treatment of pediatric hydrocephalus, the most frequently encountered condition in everyday clinical practice. The evolution of MRI and the advent of neuroendoscopic surgery have resuscitated the interest in the classification, etiology and pathophysiology of hydrocephalus. The book offers an updated overview on the recent progress in this field, and a new approach to hydrocephalus: the reader will find in it a modern and new presentation of an old disease, where genetics, endoscopy, cost-effectiveness analyses and many other aspects of the various therapies are extensively discussed. The volume will be useful not only for neurosurgeons, but for all specialists interested in the various aspects of hydrocephalus: pediatricians, radiologists, endocrinologists, pathologists and geneticists.
Download or read book Brain Edema XII written by T. Kuroiwa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.
Book Synopsis Cerebrospinal Fluid in Diseases of the Nervous System by : Robert A. Fishman
Download or read book Cerebrospinal Fluid in Diseases of the Nervous System written by Robert A. Fishman and published by . This book was released on 1992 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and authoritative text covers the anatomical and physiological aspects of cerebrospinal fluid. Also includes material on differential diagnosis, AIDS, neuro-oncology, psychiatric disorders, and the composition and clinical examination of cerebrospinal fluid, including a detailed discussion on the treatment of complications of the lumbar puncture.
Book Synopsis The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression by :
Download or read book The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Vitamin C in Human Health and Disease by : Wang Jae Lee
Download or read book Vitamin C in Human Health and Disease written by Wang Jae Lee and published by Springer. This book was released on 2019-08-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the scientific evidence for the role of vitamin C in health and disease and offers new guidance on vitamin C intake in humans. The importance of vitamin C in preventing cancer and cardiovascular disease, its relevance to aging and stress, and its impacts on each of the human body systems are thoroughly assessed on the basis of the author’s extensive research and his deep understanding, as an anatomy professor, of the body as a whole. Findings published in the international scientific literature are fully taken into account, and due consideration is also given to empirical evidence, bearing in mind that mechanisms of action cannot always be precisely defined in the absence of human experiments. Beyond providing an up-to-date scientific perspective on the effects of vitamin C, the author hopes to promote human health worldwide by encouraging proper use of the vitamin. To this end, recommendations are made on the amount of vitamin C that should be taken daily and on the best way to take it. The book will be of interest to researchers, clinicians, and all others who wish to learn more about this vitamin and its significance.
Book Synopsis Discoveries in the Human Brain by : Louise H. Marshall
Download or read book Discoveries in the Human Brain written by Louise H. Marshall and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: 170u can climb back up a stream of radiance to the sky, and back through history up the stream of time. 1 -Robert Frost topics that he judged to be important in brain his From the last years of the second millennium, tory leading into the end of the century, and was we can look back on antecedent events in neuro undertaken in response to the enthusiasm gener science with amazement that so much of modern ated by exhibition at several national and interna biomedical science was anticipated, or even said or done, in an earlier time. That surprise can be tional meetings of a series oflarge posters for which matched by appreciation for what the pioneer Magoun wrote a 27-page brochure. The posters investigators, with no inkling that they were creat were viewed by a multitude of young neuroscien ing a discipline, contributed to its emergence as a tists who wanted more, as well as by mature inves productive force in human progress. In today's tigators who were warmly pleased to see familiar names and faces from the past. The acclaim was reductionist atmosphere, in which research at the molecular level is producing breathtaking new accompanied by a veritable deluge of requests for knowledge throughout biology, the student may an illustrated, expanded publication.
Book Synopsis Magnesium in the Central Nervous System by : Robert Vink
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Book Synopsis Essentials of Hospital Neurology by : Karl E. Misulis
Download or read book Essentials of Hospital Neurology written by Karl E. Misulis and published by Oxford University Press. This book was released on 2017 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overview of hospital neurology -- Interface between hospital and outpatient neurology -- Business of hospital neurology -- Motor and sensory disturbance -- Mental status change -- Visual change -- Language ad hearing deficits -- Cranial neuropathies -- Dizziness, vertigo, and imbalance -- Pain and headache -- Neurologic complications in medical patients -- Neurologic complications in surgical patients -- Neurologic manifestations of systemic disease -- Hypoxic-ischemic encephalopathy -- Brain death and persistent vegetative state -- Vascular disease -- Infectious diseases -- Cognitive disorders -- Seizures and epilepsy -- Headache -- Neuromuscular disorders -- Demyelinating diseases -- Movement disorders -- Spinal cord disorders -- Neuro-oncology -- CSF circulation disorders -- Pregnancy and neurology -- Endocrine disorders -- Nutritional deficiencies and toxicities -- Neurotoxicology -- Neuro-ophthalmology -- Neuro-otology -- Cranial nerve disorders -- Autonomic disorders -- Traumatic brain injury -- Sleep disorders -- Developmental and genetic disorders -- Psychiatric disorders -- Toolkit assessments -- Toolkit studies -- Toolkit neurologic management -- Toolkit difficult encounters
