Retinal Ganglion Cell Survival And Axon Regeneration In The Adult Rat

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Development of the Visual System

Author : Retina Research Foundation (U.S.). Symposium
Publisher : MIT Press
ISBN 13 : 9780262121545
Total Pages : 330 pages
Book Rating : 4.1/5 (215 download)

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Book Synopsis Development of the Visual System by : Retina Research Foundation (U.S.). Symposium

Download or read book Development of the Visual System written by Retina Research Foundation (U.S.). Symposium and published by MIT Press. This book was released on 1991 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the Visual System presents a selection of current studies that clearly illustrate principles of visual system development. These range from retinal development in fish and frogs to the effects of abnormal visual experience on the primary visual cortex of the cat. The book is unique in addressing four specific and fundamental aspects of development: cell lineage and cell fate, specificity and targeting of axons, specification of visual cortex, and correlates of the critical period. Encompassing technical advances in cellular and molecular biology and in video imaging and microscopy, contributions in each of these areas provide new information at the cellular and molecular levels to complement the now classic descriptions of visual development previously available at the level of neural systems.ContributorsKaren L. Allendoerfer, David M. Altshuler, Antonella Antonini, Seymour Benzer, Edward M. Callaway, Constance L. Cepko, Hollis T. Cline, Max S. Cynader, N. W. Daw, Scott E. Fraser, K. Fox, Eckhard Friauf, Anirvan Ghosh, R. W. Guillery, William A. Harris, Christine E. Holt, Lawrence C. Katz, Susan McConnell, Pamela A. Raymond, Thomas A. Reh, Carla J. Shatz, Michael P. Stryker, Claudia A. 0. Stuermer, Mriganka Sur, David L. Turner, T. N. Wiesel

Cajal's Degeneration and Regeneration of the Nervous System

Author : Santiago Ramón y Cajal
Publisher : History of Neuroscience
ISBN 13 : 0195065166
Total Pages : 977 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis Cajal's Degeneration and Regeneration of the Nervous System by : Santiago Ramón y Cajal

Download or read book Cajal's Degeneration and Regeneration of the Nervous System written by Santiago Ramón y Cajal and published by History of Neuroscience. This book was released on 1991 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a reprint of an English translation of Cajal's original work, with abundant notes and commentaries by the editor. This text describes Cajal's fundamental contributions to neuroscience, which continue to be important today. It accurately details Cajal's ideas and data, and providesreaders with the opportunity to learn what Cajal thought about his research career and the significance of his observations. Excerpts from Tello's memorial lectures also provide a contemporary view of Cajal's work.

Body and Brain

Author : Dale Purves
Publisher : Harvard University Press
ISBN 13 : 9780674077164
Total Pages : 244 pages
Book Rating : 4.0/5 (771 download)

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Book Synopsis Body and Brain by : Dale Purves

Download or read book Body and Brain written by Dale Purves and published by Harvard University Press. This book was released on 1988 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major goal of developmental neurobiology is to understand how the nervous system is put together. A central theme that has emerged from research in this field over the last several decades is the crucial role of trophic interactions in neural assembly, and indeed throughout an animal's life. Trophic--which means nutritive--refers to long-term interdependencies between nerve cells and the cells they innervate. The theory of trophic effects presented in this book offers an explanation of how the vertebrate nervous system is related to--and regulated by--the body it serves. The theory rationalizes the nervous system's accommodation, throughout life, to the changing size and form of the body it tenants, indicating the way connections between nerve cells change in response to stimuli as diverse as growth, injury, experience, and natural selection. Dale Purves, a leading neurobiologist best known for his work on the formation and maintenance of synaptic connections, presents this theory within the historical setting of earlier ideas about neural organization--from Weiss's theory of functional reorganization to the chemoaffinity theory championed by Sperry. In addition to illuminating eighty years of work on trophic interactions, this book asks its own compelling questions: Are trophic interactions characteristic of all animals or only of those with complex nervous systems? Are trophic interactions related to learning? What does the trophic theory of neural connections imply about the currently fashionable view that the nervous system operates according to Darwinian principles? Purves lays the theoretical foundation for practical exploration of trophic interactions as they apply to neural connections, a pursuit that will help us understand how our own nervous systems generate change. The ideas in this book not only enrich neurobiology but also convey the profound relevance of neuroscience to other fields of life science.

Webvision

Author : Helga Kolb
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Webvision by : Helga Kolb

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Apoptosis and Beyond

Author : James A. Radosevich
Publisher : John Wiley & Sons
ISBN 13 : 1119432359
Total Pages : 768 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Apoptosis and Beyond by : James A. Radosevich

Download or read book Apoptosis and Beyond written by James A. Radosevich and published by John Wiley & Sons. This book was released on 2018-09-18 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.

The History of Neuroscience in Autobiography

Author : Larry R. Squire
Publisher : Elsevier
ISBN 13 : 0080534058
Total Pages : 446 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The History of Neuroscience in Autobiography by : Larry R. Squire

Download or read book The History of Neuroscience in Autobiography written by Larry R. Squire and published by Elsevier. This book was released on 1998-10-16 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second volume of autobiographical essays by distinguished senior neuroscientists; it is part of the first collection of neuroscience writing that is primarily autobiographical. As neuroscience is a young discipline, the contributors to this volume are truly pioneers of scientific research on the brain and spinal cord. This collection of fascinating essays should inform and inspire students and working scientists alike. The general reader interested in science may also find the essays absorbing, as they are essentially human stories about commitment and the pursuit of knowledge. The contributors included in this volume are: Lloyd M. Beidler, Arvid Carlsson, Donald R. Griffin, Roger Guillemin, Ray Guillery, Masao Ito. Martin G. Larrabee, Jerome Lettvin, Paul D. MacLean, Brenda Milner, Karl H. Pribram, Eugene Roberts and Gunther Stent. Key Features * Second volume in a collection of neuroscience writing that is primarily autobiographical * Contributors are senior neuroscientists who are pioneers in the field

Cell Engineering and Regeneration

Author : Heinz Redl
Publisher : Springer
ISBN 13 : 9783319088303
Total Pages : 0 pages
Book Rating : 4.0/5 (883 download)

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Book Synopsis Cell Engineering and Regeneration by : Heinz Redl

Download or read book Cell Engineering and Regeneration written by Heinz Redl and published by Springer. This book was released on 2017-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

Peripheral Nerve Regeneration

Author : Giovanna Gambarotta
Publisher : Frontiers Media SA
ISBN 13 : 2889632687
Total Pages : 302 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Peripheral Nerve Regeneration by : Giovanna Gambarotta

Download or read book Peripheral Nerve Regeneration written by Giovanna Gambarotta and published by Frontiers Media SA. This book was released on 2019-12-24 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brain Repair After Stroke

Author : Steven C. Cramer
Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Brain Repair After Stroke by : Steven C. Cramer

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Spinal Cord Injury

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309095859
Total Pages : 361 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Spinal Cord Injury by : Institute of Medicine

Download or read book Spinal Cord Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2005-08-27 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are still no cures and the challenge of restoring function in the wake of spinal cord injuries remains extremely complex. Spinal Cord Injury examines the future directions for research with the goal to accelerate the development of cures for spinal cord injuries. While many of the recommendations are framed within the context of the specific needs articulated by the New York Spinal Cord Injury Research Board, the Institute of Medicine's panel of experts looked very broadly at research priorities relating to future directions for the field in general and make recommendations to strengthen and coordinate the existing infrastructure. Funders at federal and state agencies, academic organizations, pharmaceutical and device companies, and non-profit organizations will all find this book to be an essential resource as they examine their opportunities.

The Retina in Health and Disease

Author : Maurice Ptito
Publisher : Mdpi AG
ISBN 13 : 9783036526539
Total Pages : 498 pages
Book Rating : 4.5/5 (265 download)

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Book Synopsis The Retina in Health and Disease by : Maurice Ptito

Download or read book The Retina in Health and Disease written by Maurice Ptito and published by Mdpi AG. This book was released on 2021-12-27 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.

Mesenchymal Stem Cell Derived Exosomes

Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 287 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Glaucoma

Author : Tatjana C. Jakobs
Publisher : Humana Press
ISBN 13 : 9781493984763
Total Pages : 337 pages
Book Rating : 4.9/5 (847 download)

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Book Synopsis Glaucoma by : Tatjana C. Jakobs

Download or read book Glaucoma written by Tatjana C. Jakobs and published by Humana Press. This book was released on 2018-08-30 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume introduces the reader to current methods in glaucoma research, in particular those that make use of animal disease models. Given that the retinal ganglion cells damaged and destroyed by glaucoma do not regenerate after lowering the intraocular pressure, new therapeutic approaches that protect ganglion cells directly is a vital research goal that this volume’s contents aim to aid scientists in developing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Glaucoma: Methods and Protocols serves as a useful guide for both ophthalmologists in clinical practice and researchers in the field.

Ocular Neuroprotection

Author : Leonard Levin
Publisher : CRC Press
ISBN 13 : 0824756134
Total Pages : 336 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Ocular Neuroprotection by : Leonard Levin

Download or read book Ocular Neuroprotection written by Leonard Levin and published by CRC Press. This book was released on 2003-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular neuroprotection is aimed at protecting the death of photoreceptors, retinal ganglion, or other important neurons in cases of disease or trauma. Levin (ophthalmology and neurology, U. of Wisconsin at Madison, US) and Di Polo (pathology and cell biology, U. of Montreal, Canada) present 18 chapt.

Axon Growth and Regeneration

Author : Andrew J. Murray
Publisher : Humana
ISBN 13 : 9781493907762
Total Pages : 0 pages
Book Rating : 4.9/5 (77 download)

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Book Synopsis Axon Growth and Regeneration by : Andrew J. Murray

Download or read book Axon Growth and Regeneration written by Andrew J. Murray and published by Humana. This book was released on 2014-05-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Axon Growth and Regeneration: Methods and Protocols brings together a diverse set of techniques for the study of the mechanisms underlying central nervous system axon growth, consequently providing a resource that will aid in the development of repair strategies. After an introductory section, this detailed volume continues with sections focusing on axon growth in vitro, providing a range of protocols that can be used to examine intracellular signalling pathways, axonal responses to extracellular factors and methods for quantifying outgrowth. The next section provides protocols for inducing experimental injury in vivo as well as some highly promising protocols for promoting regeneration, which segues into the final section highlighting a series of protocols that can be used to monitor the extent of axon regeneration in vivo, ranging from tract tracing to in vivo imaging and functional recovery. As a book in the Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and reliable, Axon Growth and Regeneration: Methods and Protocols aims to serve researchers studying axon regeneration with a significant set of diverse tools, vital for moving on to the next generation of exciting new discoveries in the field.

Axonal Transport, Degeneration, and Regeneration in the Visual System of the Goldfish

Author : Hartwig Wolburg
Publisher : Springer
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Axonal Transport, Degeneration, and Regeneration in the Visual System of the Goldfish by : Hartwig Wolburg

Download or read book Axonal Transport, Degeneration, and Regeneration in the Visual System of the Goldfish written by Hartwig Wolburg and published by Springer. This book was released on 1981-02 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: References ............................... 76 Subject Index ............................. 93 VIII Acknowledgments This study was funded by the Deutsche Forschungsgemeinschaft. I am indebted to Prof. Dr. W. Schlote for helpful advice and numerous discussions. I am also grateful to Dr. G. Kurz-Isler for her generous help in problems dealing with electron microscopy and to Mrs. B. Sabrowski for her careful preparation of the manuscript. The careful translation of T.C. Telger is gratefully acknowledged. The translation was financially supported by the Erwin Riesch Foundation. IX 1 Introduction One of the basic principles underlying the efficiency and adaptability of cellular meta bolism is the structural compartmentalization of the cell. Only through compartmenta lization can reaction components be kept apart prior to their reaction, isolated from other "reaction spaces" during the course of their reaction, and the reaction products incorporated into designated structures or transported to remote parts of the cell. Thus, the partitioning of the cellular substance into countless membranous spaces corresponds to the spatial segregation of reaction components, and the dynamics of intracellular membrane systems is an expression of ever-changing equilibrium condi tions and the continuous formation of new reaction spaces. It has been shown with some certainty that many of the processes in membrane dynamics can take place only with the aid of contractile proteins such as actin, myosin, and tubulin.

Axon Growth and Regeneration: Part 2

Author :
Publisher : Academic Press
ISBN 13 : 0124071694
Total Pages : 255 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Axon Growth and Regeneration: Part 2 by :

Download or read book Axon Growth and Regeneration: Part 2 written by and published by Academic Press. This book was released on 2012-12-31 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist