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Author : Josué Sznitman
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (428 download)
Download or read book Respiratory Flows in the Pulmonary Acinus and Insights on the Control of Alveolar Flows written by Josué Sznitman and published by . This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Josué Sznitman
Publisher : Sudwestdeutscher Verlag Fur Hochschulschriften AG
ISBN 13 : 9783838106847
Total Pages : 248 pages
Book Rating : 4.1/5 (68 download)
Download or read book Respiratory Flows in the Pulmonary Acinus written by Josué Sznitman and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2009 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pulmonary acinus, known as the gas exchange region of the lung, encompasses the complex of millions of sub-millimeter alveoli and may represent a potential host for pulmonary complications and diseases. These health disorders may require the inhalation of therapeutic drugs typically administered in the form of aerosolized particles. Both a precise understanding of the mechanisms leading to particle deposition as well as the need to target aerosols to specific pulmonary sites, remain ongoing challenges and depend directly on the fluid dynamics in the lung, and specifically on the microflows present in the acinar region. These considerations call not only for a deepening of our understanding of the fluid mechanics pertinent to the acinar region of the lung, but also, for the potential development of novel strategies towards improved and enhanced particle deposition inside the lung. The present thesis, which lies at the interface between engineering and medicine, is concerned with the role of convective respiratory flows in the acinar region of the lung, in conjunction with the transport and deposition of inhaled particles.
Author : Jiyuan Tu
Publisher : Springer Science & Business Media
ISBN 13 : 9400744870
Total Pages : 383 pages
Book Rating : 4.4/5 (7 download)
Download or read book Computational Fluid and Particle Dynamics in the Human Respiratory System written by Jiyuan Tu and published by Springer Science & Business Media. This book was released on 2012-09-18 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : J. S. Gravenstein
Publisher : Cambridge University Press
ISBN 13 : 1139494333
Total Pages : 489 pages
Book Rating : 4.1/5 (394 download)
Download or read book Capnography written by J. S. Gravenstein and published by Cambridge University Press. This book was released on 2011-03-17 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years capnography has gained a foothold in the medical field and is fast becoming a standard of care in anaesthesiology and critical care medicine. In addition, newer applications have emerged which have expanded the utility of capnographs in a number of medical disciplines. This new edition of the definitive text on capnography reviews every aspect of this valuable diagnostic technique. An introductory section summarises the basic physiology of carbon dioxide generation and transport in the body. A technical section describes how the instruments work, and a comprehensive clinical section reviews the use of capnography to diagnose a wide range of clinical disorders. Edited by the world experts in the technique, and with over 40 specialist contributors, Capnography, second edition, is the most comprehensive review available on the application of capnography in health care.
Author : G. Kim Prisk
Publisher : Biota Publishing
ISBN 13 : 1615044515
Total Pages : 88 pages
Book Rating : 4.6/5 (15 download)
Download or read book Pulmonary Gas Exchange written by G. Kim Prisk and published by Biota Publishing. This book was released on 2013-08-01 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.
Author : Claude Gaultier
Publisher : Springer
ISBN 13 : 1461475376
Total Pages : 464 pages
Book Rating : 4.4/5 (614 download)
Download or read book Lung Development written by Claude Gaultier and published by Springer. This book was released on 2013-05-27 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Author : Guido Ferretti
Publisher : Springer
ISBN 13 : 3319056360
Total Pages : 196 pages
Book Rating : 4.3/5 (19 download)
Download or read book Energetics of Muscular Exercise written by Guido Ferretti and published by Springer. This book was released on 2015-03-25 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the maximal power and capacity of the three major biochemical pathways - aerobic (oxygen consumption), anaerobic lactic (muscle lactate accumulation in absence of oxygen consumption), and anaerobic alactic (phosphocreatine hydrolysis) metabolism - as well as the factors that limit them. It also discusses the metabolic and cardio-pulmonary mechanisms of the dynamic response to exercise. The way and extent to which the power and capacity of the three major energy metabolisms are affected under a number of different conditions, such as training, hypoxia and microgravity, are also described.
Author : Martin Brüne
Publisher : Oxford University Press
ISBN 13 : 0192506781
Total Pages : 967 pages
Book Rating : 4.1/5 (925 download)
Download or read book The Oxford Handbook of Evolutionary Medicine written by Martin Brüne and published by Oxford University Press. This book was released on 2019-01-31 with total page 967 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine is grounded in the natural sciences, where biology stands out with regard to our understanding of human physiology and the conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, the macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system. Moreover, many adaptations to past ecologies have actually turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. One could add depression, anxiety, and other psychiatric conditions to the list. The Oxford Handbook of Evolutionary Medicine is a compilation of up-to-date insights into the evolutionary history of ourselves as a species, exploring how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine is valuable reading for students as well as scholars in the fields of medicine, biology, anthropology and psychology.
Author : Yoshiharu Ohno
Publisher : Springer Nature
ISBN 13 : 3030435393
Total Pages : 363 pages
Book Rating : 4.0/5 (34 download)
Download or read book Pulmonary Functional Imaging written by Yoshiharu Ohno and published by Springer Nature. This book was released on 2020-12-11 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the basics of pulmonary functional imaging using new CT and MR techniques and describes the clinical applications of these techniques in detail. The intention is to equip readers with a full understanding of pulmonary functional imaging that will allow optimal application of all relevant techniques in the assessment of a variety of diseases, including COPD, asthma, cystic fibrosis, pulmonary thromboembolism, pulmonary hypertension, lung cancer and pulmonary nodule. Pulmonary functional imaging has been promoted as a research and diagnostic tool that has the capability to overcome the limitations of morphological assessments as well as functional evaluation based on traditional nuclear medicine studies. The recent advances in CT and MRI and in medical image processing and analysis have given further impetus to pulmonary functional imaging and provide the basis for future expansion of its use in clinical applications. In documenting the utility of state-of-the-art pulmonary functional imaging in diagnostic radiology and pulmonary medicine, this book will be of high value for chest radiologists, pulmonologists, pulmonary surgeons, and radiation technologists.
Author : Alan H. Jobe
Publisher : Cambridge University Press
ISBN 13 : 1316665178
Total Pages : pages
Book Rating : 4.3/5 (166 download)
Download or read book Fetal and Neonatal Lung Development written by Alan H. Jobe and published by Cambridge University Press. This book was released on 2016-04-18 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.
Author : Jason H. T. Bates
Publisher : Cambridge University Press
ISBN 13 : 0521509602
Total Pages : 237 pages
Book Rating : 4.5/5 (215 download)
Download or read book Lung Mechanics written by Jason H. T. Bates and published by Cambridge University Press. This book was released on 2009-07-30 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: A modern quantitative study of lung mechanics, relating mathematical modeling and engineering principles to lung function, structure, mechanics, and disease.
Author : Didier Dreyfuss
Publisher : CRC Press
ISBN 13 : 1420019260
Total Pages : 776 pages
Book Rating : 4.4/5 (2 download)
Download or read book Ventilator-Induced Lung Injury written by Didier Dreyfuss and published by CRC Press. This book was released on 2006-03-21 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Cons
Author : Peter Slinger, MD, FRCPC
Publisher : Springer Science & Business Media
ISBN 13 : 1441901833
Total Pages : 718 pages
Book Rating : 4.4/5 (419 download)
Download or read book Principles and Practice of Anesthesia for Thoracic Surgery written by Peter Slinger, MD, FRCPC and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Anesthesia for Thoracic Surgery will serve as an updated comprehensive review covering not only the recent advances, but also topics that haven't been covered in previously published texts: extracorporeal ventilatory support, new advances in chest imaging modalities, lung isolation with a difficult airway, pulmonary thrombo-endarterectomy, and chronic post-thoracotomy pain. Additionally, the book features clinical case discussions at the end of each clinical chapter as well as tables comprising detailed anesthetic management.
Author : Ewald R. Weibel
Publisher : Academic Press
ISBN 13 : 1483225798
Total Pages : 164 pages
Book Rating : 4.4/5 (832 download)
Download or read book Morphometry of the Human Lung written by Ewald R. Weibel and published by Academic Press. This book was released on 2013-10-22 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morphometry of the Human Lung considers the developments in understanding the quantitative anatomy of the lung, and in the correlation of anatomy with physiology. This book is composed of 11 chapters, and begins with an overview of a systematic approach to a quantitative morphologic analysis of the architecture of the human lung, followed by a presentation of general problems of methodology and the derivation of reliable dimensional models of this organ. The subsequent chapters describe the methods of preparation of tissues, methods of random sampling, and adaptation of methodologies from other fields of science. These topics are followed by discussions the mathematical formulations for the translation of the data into the desired geometric forms and a technique of counting. The final chapters look into the mode of distribution and geometric forms that should eventually facilitate mathematical and physical considerations regarding the function of the lungs. These chapters also consider the application of these quantitative methods to the study of pathologic specimens, providing a most timely renovation of morphologic pathology. This book will be of value to pulmonologists, physiologists, and researchers who are interested in lung morphometry.
Author : Mitchell D. Cohen
Publisher : Springer Science & Business Media
ISBN 13 : 9780792378433
Total Pages : 492 pages
Book Rating : 4.3/5 (784 download)
Download or read book Pulmonary Immunotoxicology written by Mitchell D. Cohen and published by Springer Science & Business Media. This book was released on 2000-06-30 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference for investigators in pulmonary toxicology and immunotoxicology and for people involved in administrating and regulating matters related to inhale materials, and serviceable as a textbook for a graduate or advanced undergraduate course in pulmonary immunotoxicology. US researchers from academic and industrial laboratories provide information concerning the effects of various inhaled materials on the immune system of the respiratory tract. They cover basic background concepts including the normal structure and function of the respiratory system and its basic immunology, the major types of pathological consequences that can arise from immunomodulation within the respiratory tract, the specific major classes of airborne agents that are known to alter immune function, and risk assessment. Annotation copyrighted by Book News, Inc., Portland, OR
Author : United States. Surgeon General's Advisory Committee on Smoking and Health
Publisher :
ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.3/5 (121 download)
Download or read book Smoking and Health written by United States. Surgeon General's Advisory Committee on Smoking and Health and published by . This book was released on 1964 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
