Synthesis of Essential Drugs

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Publisher : Elsevier
ISBN 13 : 008046212X
Total Pages : 635 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Synthesis of Essential Drugs by : Ruben Vardanyan

Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

Handbook of 200 Medicinal Plants

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Author :
Publisher : Springer Nature
ISBN 13 : 3030168077
Total Pages : 2076 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Handbook of 200 Medicinal Plants by : Shahid Akbar

Download or read book Handbook of 200 Medicinal Plants written by Shahid Akbar and published by Springer Nature. This book was released on 2020-04-21 with total page 2076 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.

Natural Small Molecule Drugs from Plants

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Author :
Publisher : Springer
ISBN 13 : 9811080224
Total Pages : 702 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Natural Small Molecule Drugs from Plants by : Guan-Hua Du

Download or read book Natural Small Molecule Drugs from Plants written by Guan-Hua Du and published by Springer. This book was released on 2018-11-19 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.

Handbook of Psychopharmacology

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (75 download)

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Book Synopsis Handbook of Psychopharmacology by : Leslie L. Iversen

Download or read book Handbook of Psychopharmacology written by Leslie L. Iversen and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Hypertension E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323070671
Total Pages : 1247 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Comprehensive Hypertension E-Book by : Gregory Y. H. Lip

Download or read book Comprehensive Hypertension E-Book written by Gregory Y. H. Lip and published by Elsevier Health Sciences. This book was released on 2007-06-28 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Drug Discovery

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Publisher : Springer Science & Business Media
ISBN 13 : 1461204690
Total Pages : 443 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Drug Discovery by : Robert A. Maxwell

Download or read book Drug Discovery written by Robert A. Maxwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers some close confreres of the authors, others more distant-believed otherwise. We felt that their view reflected unrealistic thinking and that reality probably lay closer to what Beyer" maintained: We are taught to believe that if we can understand a disease it should be easy enough to figure out, say, the molecular configuration of a definitive receptor mechanism somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were discovered. There were only anecdotal accounts, and these were able to be selected and presented in ways that could be used to defend any point of view.

Psychiatry

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Publisher : Springer Nature
ISBN 13 : 303086541X
Total Pages : 624 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Psychiatry by : Konstantinos N. Fountoulakis

Download or read book Psychiatry written by Konstantinos N. Fountoulakis and published by Springer Nature. This book was released on 2021-11-26 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was the end product of life experiences, thoughts and intellectual wanderings of the author, who through his career and for the last twenty years was always serving all the three aspects of a Psychiatrist: He is a clinician, a researcher and an academic teacher. The book includes a comprehensive history of Psychiatry since antiquity and until today, with an emphasis not only on main events but also specifically and with much detail and explanations, on the chain of events that led to a particular development. At the center of this work is the question ‘What is mental illness?’ and ‘Does free will exist?’. These are questions which tantalize Psychiatrists, neuroscientists, psychologists, philosophers, patients and their families and the sensitive and educated lay persons alike. Thus, the book includes a comprehensive review and systematic elaboration on the definition and the concept of mental illness, a detailed discussion on the issue of free will as well as the state of the art of contemporary Psychiatry and the socio-political currents it has provoked. Finally the book includes a description of the academic, social and professional status of Psychiatry and Psychiatrists and a view of future needs and possible developments. A last moment addition was the chapter on conspiracy theories, as a consequence of the experience with the social media and the public response to the COVID-19 outbreak which coincided with the final stage of the preparation of the book. Their study is an excellent opportunity to dig deep into the relation among human psychology, mental health, the society and politics and to swim in intellectually dangerous waters.

Materials Handbook

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 9780071501842
Total Pages : 1244 pages
Book Rating : 4.5/5 (18 download)

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Book Synopsis Materials Handbook by : John A. Vaccari

Download or read book Materials Handbook written by John A. Vaccari and published by McGraw Hill Professional. This book was released on 2002-07-09 with total page 1244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Materials Handbook is an encyclopedic, A-to-Z organization of all types of materials, featuring their key performance properties, principal characteristics and applications in product design. Materials include ferrous and nonferrous metals, plastics, elastomers, ceramics, woods, composites, chemicals, minerals, textiles, fuels, foodstuffs and natural plant and animal substances --more than 13,000 in all. Properties are expressed in both U.S. customary and metric units and a thorough index eases finding details on each and every material. Introduced in 1929 and often known simply as "Brady's," this comprehensive, one-volume, 1244 page encyclopedia of materials is intended for executives, managers, supervisors, engineers, and technicians, in engineering, manufacturing, marketing, purchasing and sales as well as educators and students. Of the dozens of families of materials updated in the 15th Edition, the most extensive additions pertain to adhesives, activated carbon, aluminides, aluminum alloys, catalysts, ceramics, composites, fullerences, heat-transfer fluids, nanophase materials, nickel alloys, olefins, silicon nitride, stainless steels, thermoplastic elastomers, titanium alloys, tungsten alloys, valve alloys and welding and hard-facing alloys. Also widely updated are acrylics, brazing alloys, chelants, biodegradable plastics, molybdenum alloys, plastic alloys, recyclate plastics, superalloys, supercritical fluids and tool steels. New classes of materials added include aliphatic polyketones, carburizing secondary-hardening steels and polyarylene ether benzimidazoles. Carcinogens and materials likely to be cancer-causing in humans are listed for the first time.

Biomarkers in Toxicology

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Publisher : Academic Press
ISBN 13 : 0124046495
Total Pages : 1149 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Biomarkers in Toxicology by : Ramesh C Gupta

Download or read book Biomarkers in Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2014-01-25 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields. - Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more

The Role of Natural Products in Drug Discovery

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Publisher : Springer Science & Business Media
ISBN 13 : 3662040425
Total Pages : 363 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis The Role of Natural Products in Drug Discovery by : J. Mulzer

Download or read book The Role of Natural Products in Drug Discovery written by J. Mulzer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 1324001976
Total Pages : 477 pages
Book Rating : 4.3/5 (24 download)

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Book Synopsis Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness by : Anne Harrington

Download or read book Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness written by Anne Harrington and published by W. W. Norton & Company. This book was released on 2019-04-16 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Superb… a nuanced account of biological psychiatry.” —Richard J. McNally In Mind Fixers, “the preeminent historian of neuroscience” (Science magazine) Anne Harrington explores psychiatry’s repeatedly frustrated efforts to understand mental disorder. She shows that psychiatry’s waxing and waning theories have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors. Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future.

Laboratory Tests and Diagnostic Procedures

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455745022
Total Pages : 1235 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Laboratory Tests and Diagnostic Procedures by : Cynthia C. Chernecky

Download or read book Laboratory Tests and Diagnostic Procedures written by Cynthia C. Chernecky and published by Elsevier Health Sciences. This book was released on 2012-12-01 with total page 1235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Find complete answers to questions such as which laboratory tests to order or what the results might mean. Laboratory Tests and Diagnostic Procedures, 6th Edition covers more tests than any other reference of its kind, with over 900 lab tests and diagnostic procedures in all. In Part I, you'll find an alphabetical list of hundreds of diseases, conditions, and symptoms, including the tests and procedures most commonly used to confirm or rule out a suspected diagnosis. In Part II, you’ll find descriptions of virtually every laboratory and diagnostic test available. This edition is updated with the latest research and over 20 NEW test entries. Written by educator Cynthia Chernecky and clinical nurse specialist Barbara Berger, this lab reference covers today’s lab tests with concise, easy-to-use information. More than 900 laboratory tests and diagnostic procedures are included — more than any other reference! Over 600 diseases, conditions, and symptoms are listed, along with the tests used to confirm them. Alphabetical organization and A-to-Z thumb tabs make it easy to find the information you’re looking for. Alternative test names and acronyms are cross-referenced to simplify lookup. Instructions for client and family teaching help you offer guidance concerning test preparation and follow-up care. Age and gender-specific norms are provided, giving you complete lifespan coverage. Risks and Contraindications are highlighted to help you safeguard your patients and provide effective care. Panic Level Symptoms and Treatment are provided for dangerously increased and decreased levels. Minimum volumes for blood samples are included, useful when a client’s blood preservation is essential, as well as information on whether blood specimens can be drawn during hemodialysis. Tests for toxic substances are included, making this a lab, diagnostic, and toxicology book all in one. Abbreviations, measurement prefixes, and symbols are listed on the front and back covers for convenience. Information on herbal supplements indicates when a client’s use of natural remedies might affect test results. Over 20 NEW test entries present the latest tests and procedures, with a strong focus on affordable, clinically relevant genetic tests. UPDATED content includes the latest research relating to accuracy of tests, diagnostic value of results, and associated cost-benefit ratios.

The Manipulation of Human Behavior

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 ( download)

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Book Synopsis The Manipulation of Human Behavior by : Albert D. Biderman

Download or read book The Manipulation of Human Behavior written by Albert D. Biderman and published by . This book was released on 1961 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Naturopathic Endocrinology

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Author :
Publisher :
ISBN 13 : 9780692267257
Total Pages : 377 pages
Book Rating : 4.2/5 (672 download)

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Book Synopsis Fundamentals of Naturopathic Endocrinology by : Michael Friedman

Download or read book Fundamentals of Naturopathic Endocrinology written by Michael Friedman and published by . This book was released on 2014-09-13 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Naturopathic Endocrinology is designed to be a textbook for professors and students of naturopathic medicine, a desk reference for clinicians treating patients with endocrine disorders, and a convenient resource for all healthcare professionals wanting to read more about naturopathic endocrinology research. The purpose of the book is to apply Naturopathic methods of understanding, diagnosing, treating, and preventing disease to a wide range of endocrine-related disorders. This book is divided into three sections: a student textbook of naturopathic endocrinology based on current research, a clinical handbook of naturopathic protocols to diagnose and treat the most common endocrine disorders; and a selection of key clinical studies and research reports written by leading medical doctors and scientists. Case studies from clinical practice illustrate the principles outlined in the text. This book enables students of naturopathic medicine to enter their clinical training with increased confidence in understanding and treating disorders of the endocrine system. The student can draw upon the substantial knowledge and clinical experience accumulated in these pages, as well as quickly call up the many scientific references provided from recent literature in medical journals, naturopathic and botanical medicine publications, and endocrinology textbooks. This book offers practicing physicians, nurses, and other healthcare professionals a very practical clinical companion, covering established diagnostic and therapeutic protocols for endocrine disorders in quick reference charts. This book does not aim to replace standard endocrinology textbooks but rather to complement them. It is very much a cooperative effort between naturopathic and medical doctors. The work of prominent medical doctors, such as Abram Hoffer, John Lee, Denis Wilson, and Alan R. Gaby, is published alongside the work or respected naturopathic doctors such as Gregory S. Kelly. Dr Michael Friedman is a graduate of The Canadian College of Naturopathic Medicine and a former Professor of Endocrinology at the University of Bridgeport. He lives in Montpelier, Vermont.

Quality Control and Evaluation of Herbal Drugs

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Author :
Publisher : Elsevier
ISBN 13 : 0128133988
Total Pages : 788 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quality Control and Evaluation of Herbal Drugs by : Pulok K. Mukherjee

Download or read book Quality Control and Evaluation of Herbal Drugs written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2019-05-30 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. - Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes - Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis - Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine - Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues - References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Principles of Medical Pharmacology

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Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 984 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Principles of Medical Pharmacology by : Harold Kalant

Download or read book Principles of Medical Pharmacology written by Harold Kalant and published by Oxford University Press, USA. This book was released on 1985 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: Balanced, readable, and authoritative, this volume provides a well-tested introduction to basic pharmacology for students of medicine, dentistry, pharmacy, and allied health fields. The fourth edition includes new chapters on drug-induced carcinogenesis and teratogenesis, adverse drug reactions, perinatal pharmacology, geriatric pharmacology, and behavioral pharmacology. The material on clincal pharamacology and therapeutics, formerly a separate section, has been integrated into various chapters throughout the text, where it amplifies and illustrates the basic pharamcological concepts. With over 70 chapters, 46 contributors, an improved format and many new illustrations, the new edition provides a lucid, step-by-step introduction to medical pharmacology.

Essentials of Botanical Extraction

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Publisher : Academic Press
ISBN 13 : 0128025638
Total Pages : 225 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Essentials of Botanical Extraction by : Subhash C. Mandal

Download or read book Essentials of Botanical Extraction written by Subhash C. Mandal and published by Academic Press. This book was released on 2015-02-02 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery. - Reviews the history and current state of natural product drug discovery and development, highlighting successes and current issues - Explains the application of chemometric tools in extraction process design and method development - Introduces process intensification as applied to the processing of medicinal plant extracts for rapid and cost-effective extraction