Reproductive and Developmental Toxicology

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Author :
Publisher : Academic Press
ISBN 13 : 0123820332
Total Pages : 1243 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Reproductive and Developmental Toxicology by : Ramesh C Gupta

Download or read book Reproductive and Developmental Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-04 with total page 1243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproductive toxicology is a complex subject dealing with three components—parent, placenta, and fetus—and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife. - Provides a complete, integrated source of information on the key risk stages during reproduction and development - Includes coverage of emerging science such as stem cell application, toxicoproteomics, metabolomics, phthalates, infertility, teratogenicity, endocrine disruption, surveillance and regulatory considerations, and risk assessment - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis

Developmental and Reproductive Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1420040545
Total Pages : 1164 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Developmental and Reproductive Toxicology by : Ronald D. Hood

Download or read book Developmental and Reproductive Toxicology written by Ronald D. Hood and published by CRC Press. This book was released on 2005-08-30 with total page 1164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e

Reproductive Toxicology, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 9780781702256
Total Pages : 360 pages
Book Rating : 4.7/5 (22 download)

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Book Synopsis Reproductive Toxicology, Second Edition by : J Witorsch Raphael

Download or read book Reproductive Toxicology, Second Edition written by J Witorsch Raphael and published by CRC Press. This book was released on 1995-06-30 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents not only the major principles and current issues in the field but also provides a physiologic basis for the actions and reactions to reproductive toxic agents. The volume is divided into three sections. The first focuses on the current concepts of normal mammalian reproductive function from the systems to subcellular level. The second explains how toxic substances disrupt the normal functioning of elements of the mammalian reproductive system. The third section discusses other issues of long-standing or recent interest to the field, such as clinical aspects, epidemiology, and the toxic effects of low-energy electromagnetic fields and tobacco, alcohol, and other substances of abuse. Annotation copyright by Book News, Inc., Portland, OR

Principles of Food Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1466504110
Total Pages : 408 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Principles of Food Toxicology by : Tõnu Püssa

Download or read book Principles of Food Toxicology written by Tõnu Püssa and published by CRC Press. This book was released on 2013-08-20 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following in the tradition of the popular first edition, Principles of Food Toxicology, Second Edition integrates the general principles of toxicology with a systematic characterization of the most important food-borne toxicants. Ideal as a textbook in a food toxicology course, and also as a monograph dealing with principles of food toxicology as t

Principles of Toxicology, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 084932856X
Total Pages : 392 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Principles of Toxicology, Second Edition by : Stine Karen

Download or read book Principles of Toxicology, Second Edition written by Stine Karen and published by CRC Press. This book was released on 2006-01-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Principles of Toxicology Testing, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 1842145282
Total Pages : 368 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Principles of Toxicology Testing, Second Edition by : Frank A Barile

Download or read book Principles of Toxicology Testing, Second Edition written by Frank A Barile and published by CRC Press. This book was released on 2013-04-02 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.

Fundamentals of Toxicologic Pathology

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Publisher : Academic Press
ISBN 13 : 0080919324
Total Pages : 714 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fundamentals of Toxicologic Pathology by : Matthew A. Wallig

Download or read book Fundamentals of Toxicologic Pathology written by Matthew A. Wallig and published by Academic Press. This book was released on 2009-11-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels

Male Reproductive Toxicology

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Author :
Publisher :
ISBN 13 :
Total Pages : 389 pages
Book Rating : 4.:/5 (657 download)

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Book Synopsis Male Reproductive Toxicology by : Robert E. Chapin

Download or read book Male Reproductive Toxicology written by Robert E. Chapin and published by . This book was released on 1993 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Toxicologist's Pocket Handbook

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Author :
Publisher : CRC Press
ISBN 13 : 1351857177
Total Pages : 533 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis The Toxicologist's Pocket Handbook by : Michael J. Derelanko

Download or read book The Toxicologist's Pocket Handbook written by Michael J. Derelanko and published by CRC Press. This book was released on 2017-11-06 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the Toxicologist’s Pocket Handbook, like the first two editions, is a scaled-down version of the best-selling Handbook of Toxicology. It provides the most frequently used toxicology reference information in a convenient pocket-sized book. The format remains the same as the earlier editions to allow basic reference information to be located quickly, with the information placed in sections specific to subspecialties of toxicology. A detailed table of contents lists all tables and figures contained in the book by section. This expanded edition contains a number of tables not found in the second edition added to sections on lab animals, general toxicology, dermal and ocular toxicology, genetic toxicology/carcinogenesis, neurotoxicology, immunotoxicology, reproductive/developmental toxicology, industrial chemical, and pharmaceutical toxicology. New information is presented for additional laboratory animals such as swine and primates, infusion recommendations, newer methods such as the local lymph node assay, and reference safety pharmacology values for standard species. Additional information on typical genetic toxicology and immunotoxicology assays as well as in vitro assays for eye irritation are provided. Some tables from the second edition have been updated to include new information that has arisen since the earlier edition went to press. Information from the second edition, such as regulatory requirements that are no longer applicable, has been deleted.

Ovarian Toxicology, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 1466504064
Total Pages : 390 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Ovarian Toxicology, Second Edition by : Patricia B. Hoyer

Download or read book Ovarian Toxicology, Second Edition written by Patricia B. Hoyer and published by CRC Press. This book was released on 2013-09-25 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood. In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition. Topics include: Ovarian physiology and the metabolism of xenobiotics The effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries Ovarian cancer, including endocrine effects and new perspectives on chemoresistance Epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals The first book to focus specifically on ovarian toxicology, this resource is ideal for scientists in academia, regulatory agencies, and industry who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.

Small Animal Toxicology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323241980
Total Pages : 955 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Small Animal Toxicology by : Patricia A. Talcott

Download or read book Small Animal Toxicology written by Patricia A. Talcott and published by Elsevier Health Sciences. This book was released on 2012-12-03 with total page 955 pages. Available in PDF, EPUB and Kindle. Book excerpt: - 20 new chapters have been added - New topics include a list of toxicants affecting body systems, management of toxins in pregnancy, diagnostic toxicology, bacterial toxins, and cosmetic/toilet articles - Snake-bite injuries are treated in two separate, expanded chapters: Pit Vipers and Coral Snakes - Section on pharmaceuticals includes bromides, anticonvulsants, tricycle antidepressants, monoamine oxidize inhibitors, B-adrenergic toxicities, and vitamins A and D - Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods•Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods.

Biomarkers in Toxicology

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Publisher : Academic Press
ISBN 13 : 0124046495
Total Pages : 1149 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Biomarkers in Toxicology by : Ramesh C Gupta

Download or read book Biomarkers in Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2014-01-25 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields. - Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more

Metals, Fertility, and Reproductive Toxicity

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Author :
Publisher : CRC Press
ISBN 13 : 9781420023282
Total Pages : 288 pages
Book Rating : 4.0/5 (232 download)

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Book Synopsis Metals, Fertility, and Reproductive Toxicity by : Mari S. Golub

Download or read book Metals, Fertility, and Reproductive Toxicity written by Mari S. Golub and published by CRC Press. This book was released on 2005-11-10 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental endocrine disruptors have been at the heart of discussions about chemicals and their effects on fertility, but the focus has been on organic compounds and the role of metals has been largely overlooked - until now. Taking an organ-system-based approach, Metals, Fertility, and Reproductive Toxicity examines the effects of metals found in the everyday environment on fertility rates in humans and animal populations. This volume summarizes and evaluates the literature in the area of metal effects on fertility and reproduction in humans, laboratory animals, and wildlife. International experts have contributed chapters that explore how the ovary, testes, uterine system, and neuroendocrine system, among others, respond to metal exposure. Reviewing both current knowledge and cutting edge data, the chapters focus on either a particular metal or a particular population. A massive amount of data on this subject has been generated, summarized, and reviewed over the years. While there are many books available on metals toxicity and on reproductive toxicity, no current book explores both in the same volume. Culling information from throughout the literature, Metals, Fertility, and Reproductive Toxicity supplies an in-depth look at the role of metals in endocrine disruption and the spectrum of mechanisms involving metals that can influence reproduction.

Drinking Water and Health,

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Publisher : National Academies Press
ISBN 13 : 0309036879
Total Pages : 476 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Drinking Water and Health, by : National Research Council

Download or read book Drinking Water and Health, written by National Research Council and published by National Academies Press. This book was released on 1986-02-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.

Clinical Environmental Health and Toxic Exposures

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780683080278
Total Pages : 1348 pages
Book Rating : 4.0/5 (82 download)

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Book Synopsis Clinical Environmental Health and Toxic Exposures by : John Burke Sullivan

Download or read book Clinical Environmental Health and Toxic Exposures written by John Burke Sullivan and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 1348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its revised and updated Second Edition, this volume is the most comprehensive and authoritative text in the rapidly evolving field of environmental toxicology. The book provides the objective information that health professionals need to prevent environmental health problems, plan for emergencies, and evaluate toxic exposures in patients.Coverage includes safety, regulatory, and legal issues; clinical toxicology of specific organ systems; emergency medical response to hazardous materials releases; and hazards of specific industries and locations. Nearly half of the book examines all known toxins and environmental health hazards. A Brandon-Hill recommended title.

Encyclopedia of Reproduction

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Publisher : Academic Press
ISBN 13 : 0128151455
Total Pages : 3905 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Reproduction by :

Download or read book Encyclopedia of Reproduction written by and published by Academic Press. This book was released on 2018-06-29 with total page 3905 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope

Veterinary Toxicology

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Author :
Publisher : Elsevier
ISBN 13 : 0080481604
Total Pages : 1233 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Veterinary Toxicology by : Ramesh C Gupta

Download or read book Veterinary Toxicology written by Ramesh C Gupta and published by Elsevier. This book was released on 2011-04-28 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology