Signaling Pathways and Molecular Mediators in Metastasis

Download Signaling Pathways and Molecular Mediators in Metastasis PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400725574
Total Pages : 373 pages
Book Rating : 4.4/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Signaling Pathways and Molecular Mediators in Metastasis by : Alessandro Fatatis

Download or read book Signaling Pathways and Molecular Mediators in Metastasis written by Alessandro Fatatis and published by Springer Science & Business Media. This book was released on 2012-01-03 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.

The EGF Receptor Family

Download The EGF Receptor Family PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080472583
Total Pages : 175 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!


Book Synopsis The EGF Receptor Family by : Graham Carpenter

Download or read book The EGF Receptor Family written by Graham Carpenter and published by Elsevier. This book was released on 2004-02-06 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormity of the literature on growth factors, plus the breadth of the biological disciplines and technical expertise required prohibits a comprehensive review by even a multi-disciplinary panel of authors. To provide an alternative that is feasible for authors and digestible by readers, this review compendium consists of a collection of articles, each covering an aspect of teh ErbB/EGF field. This compilation features articles on growth factor ligands, neuregulins, and individual receptors. The second part of the book concentrates on the biological context of the ErbB receptors, particularly in mammary development and in cancer. It concludes with a discussion of the genetic systems that have enabled significant advances in research in this area.

Concepts and Principles of Pharmacology

Download Concepts and Principles of Pharmacology PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030353621
Total Pages : 457 pages
Book Rating : 4.0/5 (33 download)

DOWNLOAD NOW!


Book Synopsis Concepts and Principles of Pharmacology by : James E. Barrett

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Chemical Abstracts

Download Chemical Abstracts PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 2692 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Chemical Abstracts by :

Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2692 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroanatomy of Neuroendocrine Systems

Download Neuroanatomy of Neuroendocrine Systems PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9783030866327
Total Pages : 0 pages
Book Rating : 4.8/5 (663 download)

DOWNLOAD NOW!


Book Synopsis Neuroanatomy of Neuroendocrine Systems by : Valery Grinevich

Download or read book Neuroanatomy of Neuroendocrine Systems written by Valery Grinevich and published by Springer. This book was released on 2023-02-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems. The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques. In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones. Following this detailed structural and anatomical description of the neuroendocrine system, the book’s final section focuses on the hypothalamic control of neuroendocrine functions. This includes the control of circadian rhythm, metabolism and appetite via specific peptidergic circuits. This book provides essential information on the neuroanatomy and control of neuroendocrine systems, addresses cutting-edge research questions posed by recent advances in the development of potent neuroanatomical tools, and highlights the latest technologies used in neuroendocrinology research, making it a valuable reference guide for students, trainees and established researchers alike. This is the twelfth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com

Colon Cancer Diagnosis and Therapy

Download Colon Cancer Diagnosis and Therapy PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030633691
Total Pages : 374 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis Colon Cancer Diagnosis and Therapy by : Ganji Purnachandra Nagaraju

Download or read book Colon Cancer Diagnosis and Therapy written by Ganji Purnachandra Nagaraju and published by Springer Nature. This book was released on 2021-06-10 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the first of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage also addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutic, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

Bone Pathology

Download Bone Pathology PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1597453471
Total Pages : 419 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!


Book Synopsis Bone Pathology by : Jasvir S. Khurana

Download or read book Bone Pathology written by Jasvir S. Khurana and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Pathology is the second edition of the book, A Compendium of Skeletal Pathology that published 10 years ago. Similar to the prior edition, this book complements standard pathology texts and blends new but relatively established information on the molecular biology of the bone. Serving as a bench-side companion to the surgical pathologist, this new edition reflects new advances in our understanding of the molecular biology of bone. New chapters on soft-tissue sarcomas and soft-tissue tumors have been added as well as several additional chapters such as Soft-tissue pathology and Biomechanics. The volume is written by experts who are established in the field of musculoskeletal diseases. Bone Pathology is a combined effort from authors of different specialties including surgeons, pathologists, radiologists and basic scientists all of whom have in common an interest in bone diseases. It will be of great value to surgical pathology residents as well as practicing pathologists, skeletal radiologists, orthopedic surgeons and medical students.

Dietary Phytochemicals

Download Dietary Phytochemicals PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030729990
Total Pages : 262 pages
Book Rating : 4.0/5 (37 download)

DOWNLOAD NOW!


Book Synopsis Dietary Phytochemicals by : Chukwuebuka Egbuna

Download or read book Dietary Phytochemicals written by Chukwuebuka Egbuna and published by Springer Nature. This book was released on 2021-08-20 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.

Pediatric Neurology, Part II

Download Pediatric Neurology, Part II PDF Online Free

Author :
Publisher : Newnes
ISBN 13 : 0444626999
Total Pages : 545 pages
Book Rating : 4.4/5 (446 download)

DOWNLOAD NOW!


Book Synopsis Pediatric Neurology, Part II by : Olivier Dulac

Download or read book Pediatric Neurology, Part II written by Olivier Dulac and published by Newnes. This book was released on 2013-04-23 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology - International list of contributors including the leading workers in the field - Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care

Regulation of Implantation and Establishment of Pregnancy in Mammals

Download Regulation of Implantation and Establishment of Pregnancy in Mammals PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319158562
Total Pages : 271 pages
Book Rating : 4.3/5 (191 download)

DOWNLOAD NOW!


Book Synopsis Regulation of Implantation and Establishment of Pregnancy in Mammals by : Rodney D. Geisert

Download or read book Regulation of Implantation and Establishment of Pregnancy in Mammals written by Rodney D. Geisert and published by Springer. This book was released on 2015-10-08 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research endeavors to help resolve infertility, embryonic loss and recurrent abortion in humans, captive wild animals and important farm species. The present volume on “Regulation of Implantation and Establishment of Pregnancy in Mammals” brings together current reviews from leading experts to address the diversity of mechanisms by which species establish and maintain pregnancy. Implantation in rodents, dogs, pigs, cattle, sheep, horses, primates, humans and embryonic diapause in wild species are discussed. Reviews will provide current knowledge on the role of endometrial steroid receptors, adhesion factors, cytokines, interferons, steroids, prostaglandins, growth factors and immune cells involved with regulation of conceptus development.

Advances in Molecular Oncology

Download Advances in Molecular Oncology PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387691162
Total Pages : 274 pages
Book Rating : 4.3/5 (876 download)

DOWNLOAD NOW!


Book Synopsis Advances in Molecular Oncology by : Fabrizio d'Adda di Fagagna

Download or read book Advances in Molecular Oncology written by Fabrizio d'Adda di Fagagna and published by Springer Science & Business Media. This book was released on 2007-07-18 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.

Prevention and Treatment of Age-related Diseases

Download Prevention and Treatment of Age-related Diseases PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402050585
Total Pages : 365 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Prevention and Treatment of Age-related Diseases by : Suresh I.S. Rattan

Download or read book Prevention and Treatment of Age-related Diseases written by Suresh I.S. Rattan and published by Springer Science & Business Media. This book was released on 2007-05-09 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.

Medical Cell Biology

Download Medical Cell Biology PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0080919316
Total Pages : 335 pages
Book Rating : 4.0/5 (89 download)

DOWNLOAD NOW!


Book Synopsis Medical Cell Biology by : Steven R. Goodman

Download or read book Medical Cell Biology written by Steven R. Goodman and published by Academic Press. This book was released on 2007-11-26 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Cell Biology, Third Edition, focuses on the scientific aspects of cell biology important to medical students, dental students, veterinary students, and prehealth undergraduates. With its National Board-type questions, this book is specifically designed to prepare students for this exam. The book maintains a concise focus on eukaryotic cell biology as it relates to human and animal disease, all within a manageable 300-page format. This is accomplished by explaining general cell biology principles in the context of organ systems and disease. This updated version contains 60% new material and all new clinical cases. New topics include apoptosis and cell death from a neural perspective; signal transduction as it relates to normal and abnormal heart function; and cell cycle and cell division related to cancer biology. - 60% New Material! - New Topics include: - Apoptosis and cell dealth from a neural perspective - Signal transduction as it relates to normal and abnormal heart function - Cell cycle and cell division related to cancer biology - All new clinical cases - Serves as a prep guide to the National Medical Board Exam with sample board-style questions (using Exam Master(R) technology): www.exammaster.com - Focuses on eukaryotic cell biology as it related to human disease, thus making the subject more accessible to pre-med and pre-health students

Methods for Analysis of Golgi Complex Function

Download Methods for Analysis of Golgi Complex Function PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0124171834
Total Pages : 499 pages
Book Rating : 4.1/5 (241 download)

DOWNLOAD NOW!


Book Synopsis Methods for Analysis of Golgi Complex Function by :

Download or read book Methods for Analysis of Golgi Complex Function written by and published by Elsevier. This book was released on 2013-11-26 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Cell Biology looks at methods for analyzing of golgi complex function. Chapters cover such topics as in vitro reconstitution systems, fluorescence-based analysis of trafficking in mammalian cells and high content screening. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. - Covers sections on model systems and functional studies, imaging-based approaches and emerging studies - Chapters are written by experts in the field - Cutting-edge material

Model Animals in Neuroendocrinology

Download Model Animals in Neuroendocrinology PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119390885
Total Pages : 462 pages
Book Rating : 4.1/5 (193 download)

DOWNLOAD NOW!


Book Synopsis Model Animals in Neuroendocrinology by : Mike Ludwig

Download or read book Model Animals in Neuroendocrinology written by Mike Ludwig and published by John Wiley & Sons. This book was released on 2018-08-20 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model Animals in Neuroendocrinology: From Worm to Mouse to Man offers a masterclass on the opportunities that different model animals offer to the basic understanding of neuroendocrine functions and mechanisms of action and the implications of this understanding. The authors review recent advances in the field emanating from studies involving a variety of animal models, molecular genetics, imaging technologies, and behavior assays. These studies helped unravel mechanisms underlying the development and function of neuroendocrine systems. The book highlights how studies in a variety of model animals, including, invertebrates, fish, birds, rodents and mammals has contributed to our understanding of neuroendocrinology. Model Animals in Neuroendocrinology provides students, scientists and practitioners with a contemporary account of what can be learnt about the functions of neuroendocrine systems from studies across animal taxonomy. This is the seventh volume in the Masterclass in Neuroendocrinology Series, a co-publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators

Download Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators PDF Online Free

Author :
Publisher : World Scientific
ISBN 13 : 1783260335
Total Pages : 324 pages
Book Rating : 4.7/5 (832 download)

DOWNLOAD NOW!


Book Synopsis Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators by : Masaharu Takigawa

Download or read book Ccn Proteins: A New Family Of Cell Growth And Differentiation Regulators written by Masaharu Takigawa and published by World Scientific. This book was released on 2005-06-17 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CCN Proteins are thought to play key roles in the biology of normal cell, tissue, organ, and body, and altered expression of CCN proteins is associated with several pathologies, including fibrosis and cancer. Because of its importance, the CCN field is expanding at a fast pace. Research articles in this field have recently increased logarithmically, and a book that is up-to-date, comprehensive, authoritative and affords insights into the biological roles of CCN proteins, is timely.CCN Protein: A New Family of Cell Growth and Differentiation Regulators presents the most recent progress in the field of CCN proteins, a new family of secretory signaling molecules that are involved in several fundamental biological progress. These proteins share a unique multimodular organization and present a partial identity with four families of regulatory proteins controling growth and development. The book covers the roles of CCN proteins in the control of cell proliferation and differentiation during normal development, wound repair, chondrogenesis and bone development, angiogenesis, tissue regeneration, fibrosis, renal diseases and cancer development.

Principles of Endocrinology and Hormone Action

Download Principles of Endocrinology and Hormone Action PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9783319446745
Total Pages : 0 pages
Book Rating : 4.4/5 (467 download)

DOWNLOAD NOW!


Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore

Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.