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Author : Daniella Rylander Ottosson
Publisher : Frontiers Media SA
ISBN 13 : 2889710459
Total Pages : 140 pages
Book Rating : 4.8/5 (897 download)
Download or read book Regeneration and Brain Repair written by Daniella Rylander Ottosson and published by Frontiers Media SA. This book was released on 2021-07-15 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Donald G. Stein
Publisher : Oxford University Press, USA
ISBN 13 : 9780195119183
Total Pages : 190 pages
Book Rating : 4.1/5 (191 download)
Download or read book Brain Repair written by Donald G. Stein and published by Oxford University Press, USA. This book was released on 1997 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over a half million people each year suffer brain-damaging injuries and diseases--but the outlook for their eventual recovery is far more hopeful than it was just a short while ago. In Brain Repair, three internationally renowned neuroscientists team up to offer an intriguing and up-to-the-minute introduction to the explosive advances being made in the research, technology, and treatment of brain damage. The key to neuroscience's most exciting discoveries to date is a theory that is rapidly gaining adherents in the scientific community--the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. In clear, accessible language, the authors show us that the brain manufactures a host of complex chemicals that actually foster growth in damaged brain cells. We visit the laboratories where researchers are untangling the mystery of Parkinson's disease and trying to understand what goes wrong in stroke victims, and why some, thought permanently impaired, show remarkable improvements. In addition, they discuss how even today misguided ideas can adversely affect how physicians treat patients. And, along the way, they detail the fascinating history of how brain structure and functioning has been understood and studied, from prehistoric times to the present. A best-selling volume in France and Mexico, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.
Author : James W. Fawcett
Publisher : Oxford University Press, USA
ISBN 13 : 9780198523376
Total Pages : 466 pages
Book Rating : 4.5/5 (233 download)
Download or read book Brain Damage, Brain Repair written by James W. Fawcett and published by Oxford University Press, USA. This book was released on 2002 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many neurological conditions are caused by damage to neurons and glial cells. For most of these diseases there is at present no effective treatments to minimise the extent of neuronal and glial loss, and no effective way of replacing what has been lost. This picture is rapidly changing. Developments in basic neuroscience have produced various potential therapies that can protect neurons and glia following traumatic, anoxic, infectious and immunological damage. This book describes the various conditions that lead to damage to the nervous system, and the ways in which they may be ameliorated. It covers the burgeoning science of reconstruction of the nervous system, through neuronal, glial and stem cell transplantation, axon regeneration, remyelination, plasticity and pharmacological interventions. The clinical conditions to which these treatments will be applied and their assessment are described. This is the first book to cover this enormous and expanding field of neuroscience and neurology. It will be useful to students and scientists working in the field of nervous system damage and reconstruction, and also to clinicians who wish to look forward to the developments which will shape the future of their practice.
Author : T. Herdegen
Publisher : Springer Science & Business Media
ISBN 13 : 1402025416
Total Pages : 707 pages
Book Rating : 4.4/5 (2 download)
Download or read book Brain Damage and Repair written by T. Herdegen and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book builds a novel bridge from molecular research to clinical therapy. This approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes underlying migration disorders, axonal injury, repair and regeneration.
Author : Kim Heidenreich
Publisher : Academic Press
ISBN 13 : 0128027010
Total Pages : 354 pages
Book Rating : 4.1/5 (28 download)
Download or read book New Therapeutics for Traumatic Brain Injury written by Kim Heidenreich and published by Academic Press. This book was released on 2016-09-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic
Author : Jeffrey Kordower
Publisher : Elsevier
ISBN 13 : 0080556981
Total Pages : 523 pages
Book Rating : 4.0/5 (85 download)
Download or read book CNS Regeneration written by Jeffrey Kordower and published by Elsevier. This book was released on 2011-04-28 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS
Author : Mathias Bähr
Publisher : Springer Science & Business Media
ISBN 13 : 0387301283
Total Pages : 264 pages
Book Rating : 4.3/5 (873 download)
Download or read book Brain Repair written by Mathias Bähr and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies. Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics. Thus, this book is unique in bridging the gap between basic and clinical research. It will be a valuable tool for all students, researchers and clinicians interested in understanding the brain's capacity to cope with lesions and interested in learning about emerging new therapy concepts.
Author : William M. Reichert
Publisher : CRC Press
ISBN 13 : 1420009303
Total Pages : 300 pages
Book Rating : 4.4/5 (2 download)
Download or read book Indwelling Neural Implants written by William M. Reichert and published by CRC Press. This book was released on 2007-12-17 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : Steven C. Cramer
Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)
Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Author : James W. Fawcett
Publisher :
ISBN 13 : 9780191724534
Total Pages : 466 pages
Book Rating : 4.7/5 (245 download)
Download or read book Brain Damage, Brain Repair written by James W. Fawcett and published by . This book was released on 2001 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the various conditions that lead to damage to the nervous system, and the ways in which they may be ameliorated. It covers the burgeoning science of reconstruction of the nervous system, through transplantation and regeneration.
Author :
Publisher : Newnes
ISBN 13 : 0444595457
Total Pages : 405 pages
Book Rating : 4.4/5 (445 download)
Download or read book Functional Neural Transplantation III written by and published by Newnes. This book was released on 2012-12-31 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Author : Shuxin Li
Publisher : Frontiers Media SA
ISBN 13 : 288974633X
Total Pages : 399 pages
Book Rating : 4.8/5 (897 download)
Download or read book Advances in CNS Repair, Regeneration, and Neuroplasticity: From Basic Mechanisms to Therapeutic Strategies written by Shuxin Li and published by Frontiers Media SA. This book was released on 2022-03-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jean-Didier Vincent
Publisher : Columbia University Press
ISBN 13 : 0231534213
Total Pages : 197 pages
Book Rating : 4.2/5 (315 download)
Download or read book The Custom-Made Brain written by Jean-Didier Vincent and published by Columbia University Press. This book was released on 2014-06-03 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two leading neuroscientists examine how the brain is in flux and how this applies to addressing neurological, cognitive, and emotional health. Beginning with a survey of the fundamental scientific developments that led to our current understanding of the regenerative mind, the authors elucidate the breakthrough neurobiological studies that paved the way for our present understanding of the brain’s plasticity and regenerative capabilities. They then discuss the application of these findings to such issues as depression, dyslexia, schizophrenia, and cognitive therapy, incorporating the latest technologies in neuroimaging, optogenetics, and nanotechnology. Their work shows the brain is anything but a static organ, ceasing to grow as human beings become adults. Rather, the brain is dynamic, evolving organically in relation to physical, cultural, historical, and affective stimuli, a plasticity that provides early hope to survivors of trauma and degenerative disorders. “Highly informative, up to date, and entertaining, The Custom-Made Brain emphasizes that the brain is constantly being constructed during an individual’s lifetime, like a medieval cathedral that is never finished and yet ages without reaching ‘maturity.’ The brain, like the cathedral, is forever being repaired and restored. A stimulating read.” —Israel Rosenfield, City University of New York, author of The Invention of Memory: A New View of the Brain “This short account succeeds in an original and thought-provoking manner. It will become a valuable resource for clinicians who manage the care of those disabled by stroke, brain injury, or dementia. Many young scientists will be encouraged to take up the challenge of brain repair in the face of decades of therapeutic pessimism.” —Lawrence Whalley, University of Aberdeen, author of The Aging Brain
Author : Philip V. Peplow
Publisher : Springer
ISBN 13 : 9783031497438
Total Pages : 0 pages
Book Rating : 4.4/5 (974 download)
Download or read book Regenerative Medicine and Brain Repair written by Philip V. Peplow and published by Springer. This book was released on 2024-02-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest knowledge, trends, and advances in cell transplantation and innovations in developing microspheres, 3D biomaterial constructs to enhance transfer, and cell survival to specific regions of the brain. Neurodegenerative diseases and brain injury are increasing. Medications currently only temporarily reduce some of the symptoms but do not cure or delay progression of the disease. Development of effective treatments dramatically improves the independent living and quality of life of patients. Cell transplantation strategies offer an approach to facilitating brain repair, but efficacy is often limited by low in vivo survival rates of cells that are injected in suspension. Transplanting cells that are attached to or encapsulated within a biomaterial construct has the advantage of maintaining cell-cell and cell-material interactions and improving cell survival in vivo. Biomaterials that have been used in preclinical studies to assist with in vivo cell transfer and survival include heparin-chitosan microspheres, poly(lactic-co-glycolic acid) microspheres, RADA 16 microspheres, poly(desaminotyrosyl tyrosine ethyl ester carbonate) microscale scaffolds, carbon nanotubes, collagen-chitosan scaffolds, poly(L-lactic acid) scaffolds, agarose hydrogels, gelatin methacrylate hydrogels, and agarose micro-columns with an extracellular matrix interior. Incorporating growth factors (e.g., glial-derived neurotrophic factor, neurotrophin 3) into the biomaterial constructs increased cell survival and incorporation into the host tissue. International experts in the fields of both experimental and clinical neurological research contribute chapters to this book and discuss the latest achievements in cell transplantation and matrix-assisted cell transfer/survival technologies for diseases such as Alzheimer’s disease, Parkinson’s disease, and brain injuries such as stroke and traumatic brain injury. It is envisaged that research findings in experimental animal models of Alzheimer’s disease, Parkinson’s disease, traumatic brain injury, and stroke promote clinical trials using biomaterial-assisted transfer of cells.
Author : Norman Saunders
Publisher : CRC Press
ISBN 13 : 0203304489
Total Pages : 354 pages
Book Rating : 4.2/5 (33 download)
Download or read book Degeneration and Regeneration in the Nervous System written by Norman Saunders and published by CRC Press. This book was released on 2003-09-02 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.
Author : Paolo Peretto
Publisher : Frontiers Media SA
ISBN 13 : 2889194949
Total Pages : 121 pages
Book Rating : 4.8/5 (891 download)
Download or read book Adult neurogenesis twenty years later: physiological function versus brain repair written by Paolo Peretto and published by Frontiers Media SA. This book was released on 2015-05-01 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity. On a theoretical basis, this achievement opened new perspectives for therapeutic approaches in restorative and regenerative neurology. Nevertheless, in spite of striking advancement concerning the molecular and cellular mechanisms which allow and regulate the neurogenic process, its exploitation in mammals for brain repair strategies remains unsolved. In non-mammalian vertebrates, adult neurogenesis also contributes to brain repair/regeneration. In mammals, neural stem cells do respond to pathological conditions in the so called "reactive neurogenesis", yet without substantial regenerative outcome. Why, even in the presence of stem cells in the brain, we lack an effective reparative outcome in terms of regenerative neurology, and which factors hamper the attainment of this goal? Essentially, what remains unanswered is the question whether (and how) physiological functions of adult neurogenesis in mammals can be exploited for brain repair purposes.
