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Recombinant Dna Research
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Book Synopsis Oversight and Review of Clinical Gene Transfer Protocols by : Institute of Medicine
Download or read book Oversight and Review of Clinical Gene Transfer Protocols written by Institute of Medicine and published by National Academies Press. This book was released on 2014-03-27 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene transfer research is a rapidly advancing field that involves the introduction of a genetic sequence into a human subject for research or diagnostic purposes. Clinical gene transfer trials are subject to regulation by the U.S. Food and Drug Administration (FDA) at the federal level and to oversight by institutional review boards (IRBs) and institutional biosafety committees (IBCs) at the local level before human subjects can be enrolled. In addition, at present all researchers and institutions funded by the National Institutes of Health (NIH) are required by NIH guidelines to submit human gene transfer protocols for advisory review by the NIH Recombinant DNA Advisory Committee (RAC). Some protocols are then selected for individual review and public discussion. Oversight and Review of Clinical Gene Transfer Protocols provides an assessment of the state of existing gene transfer science and the current regulatory and policy context under which research is investigated. This report assesses whether the current oversight of individual gene transfer protocols by the RAC continues to be necessary and offers recommendations concerning the criteria the NIH should employ to determine whether individual protocols should receive public review. The focus of this report is on the standards the RAC and NIH should use in exercising its oversight function. Oversight and Review of Clinical Gene Transfer Protocols will assist not only the RAC, but also research institutions and the general public with respect to utilizing and improving existing oversight processes.
Download or read book Recombinant DNA Research written by and published by . This book was released on 1975 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Documents relating to "NIH guidelines for research involving recombinant DNA molecules," Feb. 1975/June 1976- .
Author :Federal Interagency Committee on Recombinant DNA Research. Subcommittee on International Issues Publisher : ISBN 13 : Total Pages :140 pages Book Rating :4.:/5 ( download)
Book Synopsis Report of the Federal Interagency Committee on Recombinant DNA Research by : Federal Interagency Committee on Recombinant DNA Research. Subcommittee on International Issues
Download or read book Report of the Federal Interagency Committee on Recombinant DNA Research written by Federal Interagency Committee on Recombinant DNA Research. Subcommittee on International Issues and published by . This book was released on 1977 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recombinant DNA Methodology written by and published by Academic Press. This book was released on 2014-05-19 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant DNA methods are powerful, revolutionary techniques that allow the isolation of single genes in large amounts from a pool of thousands or millions of genes and the modification of these isolated genes or their regulatory regions for reintroduction into cells for expression at the RNA or protein levels. These attributes lead to the solution of complex biological problems and the production of new and better products in the areas of medicine, agriculture, and industry. Recombinant DNA Methodology, a volume in the Selected Methods in Enzymology series produced in benchtop format, contains a selection of key articles from Volumes 68, 100, 101, 153, 154, and 155 of Methods in Enzymology. The essential and widely used procedures provided at an affordable price will be an invaluable aid to the graduate student and the researcher. Enzymes in DNA research DNA isolation, hybridization, and cloning DNA sequence analysis cDNA cloning Gene products Identification of cloned genes and mapping of genes Monitoring cloned gene expression Cloning and transferring of genes into yeast cells Cloning and transferring of genes into plant cells Cloning and transferring of genes into animal cells Site-directed mutagenesis Protein engineering Expression vectors
Book Synopsis Recombinant DNA: Genes and Genomes by : James D. Watson
Download or read book Recombinant DNA: Genes and Genomes written by James D. Watson and published by Macmillan. This book was released on 2007 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant DNA, Third Edition, is an essential text for undergraduate, graduate, and professional courses in Genomics, Cell and Molecular Biology, Recombinant DNA, Genetic Engineering, Human Genetics, Biotechnology, and Bioinformatics. The Third Edition of this landmark text offers an authoritative, accessible, and engaging introduction to modern, genome-centered biology from its foremost practitioners. The new edition explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the most relevant and exciting examples of current research and landmark experiments that redefined our understanding of DNA. As a result, students learn how working scientists make real high-impact discoveries. The first chapters provide an introduction to the fundamental concepts of genetics and genomics, an inside look at the Human Genome Project, bioinformatic and experimental techniques for large-scale genomic studies, and a survey of epigenetics and RNA interference. The final chapters cover the quest to identify disease-causing genes, the genetic basis of cancer, and DNA fingerprinting and forensics. In these chapters the authors provide examples of practical applications in human medicine, and discuss the future of human genetics and genomics projects.
Book Synopsis Report of the Federal Interagency Committee on Recombinant DNA Research by : Federal Interagency Committee on Recombinant DNA Research
Download or read book Report of the Federal Interagency Committee on Recombinant DNA Research written by Federal Interagency Committee on Recombinant DNA Research and published by . This book was released on 1977 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Health and the Environment Publisher : ISBN 13 : Total Pages :492 pages Book Rating :4.:/5 (319 download)
Book Synopsis Recombinant DNA Research Act of 1977 by : United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Health and the Environment
Download or read book Recombinant DNA Research Act of 1977 written by United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Health and the Environment and published by . This book was released on 1977 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recombinant DNA written by John Richards and published by Elsevier. This book was released on 2012-12-02 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant DNA: Science, Ethics, and Politics emerged from papers presented at a conference, Ethical and Methodological Dimensions of Scientific Research: Recombinant DNA, A Case Study, held at the University of Georgia, April 15-16, 1977. Starting with an introduction to the methods and uses of recombinant DNA technology, the remaining contributions made by researchers at the symposium are organized into four parts. The first part contains papers on the development and utilization of recombinant DNA technology; genetic engineering in agriculture; and the dangers of unrestricted research. The second part focuses on the ethical aspects of recombinant DNA research. It includes studies such as ethical prerequisites for examining biological research; the limitations of broad moral policies; and ethical theories underlying the recombinant DNA controversy. The third part examines the legal aspects of recombinant DNA research and examines the issue of whether such research should be regulated. The papers in the fourth part consider directors for future research.
Book Synopsis Recombinant DNA by : James D. Watson
Download or read book Recombinant DNA written by James D. Watson and published by Macmillan. This book was released on 1992-02-15 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of recombitant DNA techniques and surveys advances in recombinant molecular genetics, experimental methods and their results.
Author :United States. Congress. House. Committee on Science and Technology. Subcommittee on Science, Research, and Technology Publisher : ISBN 13 : Total Pages :1322 pages Book Rating :4.0/5 (8 download)
Book Synopsis Science Policy Implications of DNA Recombinant Molecule Research by : United States. Congress. House. Committee on Science and Technology. Subcommittee on Science, Research, and Technology
Download or read book Science Policy Implications of DNA Recombinant Molecule Research written by United States. Congress. House. Committee on Science and Technology. Subcommittee on Science, Research, and Technology and published by . This book was released on 1977 with total page 1322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Institute of General Medical Sciences (U.S.). Office of Recombinant DNA Activities Publisher : ISBN 13 : Total Pages :36 pages Book Rating :4.:/5 ( download)
Book Synopsis Administrative Practices Supplement to the NIH Guidelines for Research Involving Recombinant DNA Molecules by : National Institute of General Medical Sciences (U.S.). Office of Recombinant DNA Activities
Download or read book Administrative Practices Supplement to the NIH Guidelines for Research Involving Recombinant DNA Molecules written by National Institute of General Medical Sciences (U.S.). Office of Recombinant DNA Activities and published by . This book was released on 1979 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Calculating the Secrets of Life by : National Research Council
Download or read book Calculating the Secrets of Life written by National Research Council and published by National Academies Press. This book was released on 1995-04-06 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important roleâ€"in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.
Book Synopsis The Regulation of Recombinant DNA Research by : Wisconsin. Legislature. Legislative Reference Bureau
Download or read book The Regulation of Recombinant DNA Research written by Wisconsin. Legislature. Legislative Reference Bureau and published by . This book was released on 1978 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enzymology Primer for Recombinant DNA Technology by : Hyone-Myong Eun
Download or read book Enzymology Primer for Recombinant DNA Technology written by Hyone-Myong Eun and published by Elsevier. This book was released on 1996-06-03 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes are indispensable tools in recombinant DNA technology and genetic engineering. This book not only provides information for enzymologists, but does so in a manner that will also aid nonenymologists in making proper use of these biocatalysts in their research. The Enzymology Primer for Recombinant DNA Technology includes information not usually found in the brief descriptions given in most books on recombinant DNA methodology and gene cloning. Provides essential basics as well as up-to-date information on enzymes most commonly used in recombinant DNA technology Presents information in an easily accessible format to serve as a quick reference source Leads to a better understanding of the role of biocatalysts in recombinant DNA techniques
Author :United States. Congress. Senate. Committee on Commerce, Science, and Transportation. Subcommittee on Science, Technology, and Space Publisher : ISBN 13 : Total Pages :116 pages Book Rating :4.3/5 (91 download)
Book Synopsis Recombinant DNA Research and Its Applications by : United States. Congress. Senate. Committee on Commerce, Science, and Transportation. Subcommittee on Science, Technology, and Space
Download or read book Recombinant DNA Research and Its Applications written by United States. Congress. Senate. Committee on Commerce, Science, and Transportation. Subcommittee on Science, Technology, and Space and published by . This book was released on 1978 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sources of Medical Technology by : Institute of Medicine
Download or read book Sources of Medical Technology written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-01 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Book Synopsis Recombinant DNA Research and Viruses by : Yechiel Becker
Download or read book Recombinant DNA Research and Viruses written by Yechiel Becker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of recombinant DNA technology has made a marked impact on molecular virology. The cleavage of viral DNA genomes with restriction enzymes and the cloning of such DNA fragments in bacterial p1asmids has led to the amplification of selected viral DNA fragments for sequencing and gene expression. RNA virus genomes which can be transcribed to their cDNA form were also cloned in bacterial p1asmids, facilitating the study of RNA virus genes. With the elucidation in recent years of the promoter sequence of various viral genes and the expression of these genes in bacteria or yeast, the understanding of many viral gene functions has made great progress. Cloning and expression of viral genes in mammalian cells was made possible by the construction of shuttle plasmid vectors which carry the origins of DNA replication from bacteria and/or mammalian viruses. The expression of viral genes in bacteria, yeast and eukaryotic cells gives reason to hope that it will be possible to produce viral antigens in large quantities for use as human or animal vaccines. The present volume attempts to capture for the reader some of the high lights of recombinant DNA research in the field of animal and plant viruses.
