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Recent Trends In Molecular Recognition
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Book Synopsis Recent Trends in Molecular Recognition by : F. Diederich
Download or read book Recent Trends in Molecular Recognition written by F. Diederich and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, it is clearly recognized that molecular recognition impacts and determines all life processes. It has become a key research field in both chemistry and biology and the emerging interface of what now is being called "chemical biology". The technological advances derived from this knowledge are particularly important, diverse, and directly evident in the pharmaceutical industry. Under the auspices of the Ernst Schering Research Foundation, a workshop held in Berlin in February 1998 addressed novel basic developments of potential relevance to drug research efforts. A balance of timely research topics in molecular recognition is presented in the lectures delivered by a multidisciplinary international panel of renowned scholars and documented in this volume.
Book Synopsis Recent Advances and Trends in Molecular Recognition Based Membranes by : Jamie A. Hestekin
Download or read book Recent Advances and Trends in Molecular Recognition Based Membranes written by Jamie A. Hestekin and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Molecular Recognition by : A.D. Buckingham
Download or read book Principles of Molecular Recognition written by A.D. Buckingham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of molecular recognition in chemistry and biology is reflected in a recent upsurge in relevant research, promoted in particular by high-profile initiatives in this area in Europe, the USA and Japan. Although molecular recognition is necessarily microscopic in origin, its consequences are de facto macroscopic. Accordingly, a text that starts with intermolecular interactions between simple molecules and builds to a discussion of molecular recognition involving larger scale systems is timely. This book was planned with such a development in mind. The book begins with an elementary but rigorous account of the various types of forces between molecules. Chapter 2 is concerned with the hydrogen bond between pairs of simple molecules in the gas phase, with particular reference to the preferred relative orientation of the pair and the ease with which this can be distorted. This microscopic view continues in chapter 3 wherein the nature of interactions between solute molecules and solvents or between two or more solutes is examined from the experimental standpoint, with various types of spectroscopy providing the probe of the nature of the interactions. Molecular recognition is central to the catalysis of chemical reactions, especially when bonds are to be broken and formed under the severe con straint that a specific configuration is to result, as in the production of enan tiotopically pure compounds. This important topic is considered in chapter 4.
Book Synopsis MOLECULAR RECOGNITION: BIOTECHNOLOGY, CHEMICAL ENGINEERING AND MATERIALS APPLICATIONS by : JASON A. MCEVOY
Download or read book MOLECULAR RECOGNITION: BIOTECHNOLOGY, CHEMICAL ENGINEERING AND MATERIALS APPLICATIONS written by JASON A. MCEVOY and published by Lulu.com. This book was released on 2011 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Dynamic Force Spectroscopy and Biomolecular Recognition by : Anna Rita Bizzarri
Download or read book Dynamic Force Spectroscopy and Biomolecular Recognition written by Anna Rita Bizzarri and published by CRC Press. This book was released on 2012-01-25 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. In six chapters, Dynamic Force Spectroscopy and Biomolecular Recognition covers the most recent ideas and advances in the field of DFS applied to biorecognition: Chapter 1: Reviews the basic and novel aspects of biorecognition and discusses the emerging capabilities of single-molecule techniques to disclose kinetic properties and molecular mechanisms usually hidden in bulk measurements Chapter 2: Describes the basic principle of atomic force microsocopy (AFM) and DFS, with particular attention to instrumental and theoretical aspects more strictly related to the study of biomolecules Chapter 3: Overviews the theoretical background in which experimental data taken in nonequilibrum measurements of biomolecular unbinding forces are extrapolated to equilibrium conditions Chapter 4: Reviews the most common and efficient strategies adopted in DFS experiments to immobilize the interacting biomolecules to the AFM tip and to the substrate Chapter 5: Presents and discusses the most representative aspects related to the analysis of DFS data and the challenges of integrating well-defined criteria to calibrate data in automatic routinary procedures Chapter 6: Overviews the most relevant DFS applications to study biorecognition processes, including the biotin/avidin pair, and selected results on various biological complexes, including antigen/antibody, proteins/DNA, and complexes involved in adhesion processes Chapter 7: Summarizes the main results obtained by DFS applied to study biorecognition processes with forthcoming theoretical and experimental advances Although DFS is a widespread, worldwide technique, no books focused on this subject have been available until now. Dynamic Force Spectroscopy and Biomolecular Recognition provides the state of the art of experimental data analysis and theoretical procedures, making it a useful tool for researchers applying DFS to study biorecognition processes.
Book Synopsis Spectroscopy of Biological Molecules: Modern Trends by : P. Carmona
Download or read book Spectroscopy of Biological Molecules: Modern Trends written by P. Carmona and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1997 European Conference on Spectroscopy of Biological Molecules (ECSBM) is the seventh in a biennial series of conferences devoted to the applications of molecular spectroscopy to biological molecules and related systems. The interest of these conferences rests mainly on the relationship between the structure and physiological activity of biological molecules and related systems of which these molecular species form part. This volume ofECSBM contains articles prepared by the invited lecturers and those making poster presentations at the seventh ECSBM. The reader will find mainly applications of vibrational spectroscopy to protein structure and dynamics, biomembranes, molecular recognition, nucleic acids and other biomolecules and biological systems containing specific chromophors. Biomedical applications of vibrational spectroscopy are expanding rapidly. On the other hand, a significant number of the papers describe applications of other methods, such as NMR, circular dichroism, optical absorption and fluorescence, X-ray absorption and diffraction and other theoretical methods. One aim has been to achieve a well balanced, critically comparative review of recent progress in the field of biomolecular structure, bonding and dynamics based on applications of the above spectroscopic methods. A great part of the contributions included in this volume are devoted to biomedical and biotechnological applications and provide a broadly based account of recent applicationS in this field. The content of this book has been organized in sections corresponding mainly to the different types of biological molecules investigated. This book includes also another section related to theoretical methods where MO calculations of vibrational frequencies dominate clearly the topic.
Book Synopsis Molecular Recognition of DNA Double Helix by : Abhijit Saha
Download or read book Molecular Recognition of DNA Double Helix written by Abhijit Saha and published by Springer. This book was released on 2018-03-22 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.
Book Synopsis New Scaffolds for Molecular Recognition by : Ken Shimizu
Download or read book New Scaffolds for Molecular Recognition written by Ken Shimizu and published by . This book was released on 1995 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Recognition Complete Self-Assessment Guide by : Gerardus Blokdyk
Download or read book Molecular Recognition Complete Self-Assessment Guide written by Gerardus Blokdyk and published by 5starcooks. This book was released on 2018-05-27 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are your current levels and trends in key measures or indicators of Molecular recognition product and process performance that are important to and directly serve your customers? how do these results compare with the performance of your competitors and other organizations with similar offerings? How will we insure seamless interoperability of Molecular recognition moving forward? Why should we adopt a Molecular recognition framework? Do Molecular recognition rules make a reasonable demand on a users capabilities? Will new equipment/products be required to facilitate Molecular recognition delivery for example is new software needed? Defining, designing, creating, and implementing a process to solve a challenge or meet an objective is the most valuable role... In EVERY group, company, organization and department. Unless you are talking a one-time, single-use project, there should be a process. Whether that process is managed and implemented by humans, AI, or a combination of the two, it needs to be designed by someone with a complex enough perspective to ask the right questions. Someone capable of asking the right questions and step back and say, 'What are we really trying to accomplish here? And is there a different way to look at it?' This Self-Assessment empowers people to do just that - whether their title is entrepreneur, manager, consultant, (Vice-)President, CxO etc... - they are the people who rule the future. They are the person who asks the right questions to make Molecular recognition investments work better. This Molecular recognition All-Inclusive Self-Assessment enables You to be that person. All the tools you need to an in-depth Molecular recognition Self-Assessment. Featuring 704 new and updated case-based questions, organized into seven core areas of process design, this Self-Assessment will help you identify areas in which Molecular recognition improvements can be made. In using the questions you will be better able to: - diagnose Molecular recognition projects, initiatives, organizations, businesses and processes using accepted diagnostic standards and practices - implement evidence-based best practice strategies aligned with overall goals - integrate recent advances in Molecular recognition and process design strategies into practice according to best practice guidelines Using a Self-Assessment tool known as the Molecular recognition Scorecard, you will develop a clear picture of which Molecular recognition areas need attention. Your purchase includes access details to the Molecular recognition self-assessment dashboard download which gives you your dynamically prioritized projects-ready tool and shows your organization exactly what to do next. Your exclusive instant access details can be found in your book.
Book Synopsis Protein-Ligand Interactions by : Hans-Joachim Böhm
Download or read book Protein-Ligand Interactions written by Hans-Joachim Böhm and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences. The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specificity as well as stability of ligand binding. Molecular recognition is thus a central topic in the development of active substances, since stability and specificity determine whether a substance can be used as a drug. Nowadays, computer-aided prediction and intelligent molecular design make a large contribution to the constant search for, e. g., improved enzyme inhibitors, and new concepts such as that of pharmacophores are being developed. An up-to-date presentation of an eternally young topic, this book is an indispensable information source for chemists, biochemists and pharmacologists dealing with the binding of ligands to proteins.
Book Synopsis Uncovering Hidden Patterns of Molecular Recognition by : Sebastian Raschka
Download or read book Uncovering Hidden Patterns of Molecular Recognition written by Sebastian Raschka and published by . This book was released on 2017 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular recognition written by and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Searching for Molecular Solutions by : Ian S. Dunn
Download or read book Searching for Molecular Solutions written by Ian S. Dunn and published by John Wiley & Sons. This book was released on 2010-01-05 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive look at empirical approaches to molecular discovery, their relationships with rational design, and the future of both Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies. Along with a broad overview of the subject matter, Searching for Molecular Solutions explores: The differing modes of molecular discovery Biological precedents for evolutionary approaches Directed evolutionary methods and related areas Enzyme evolution and design Functional nucleic acid discovery Antibodies and other recognition molecules General aspects of molecular recognition Small molecule discovery approaches Rational molecular design The interplay between empirical and rational strategies and their ongoing roles in the future of molecular discovery Searching for Molecular Solutions covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspects of molecular discovery, as well as the thought processes behind experimental approaches.
Book Synopsis New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications by : Marc J.M. Abadie
Download or read book New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications written by Marc J.M. Abadie and published by Springer Nature. This book was released on 2021-05-26 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
Book Synopsis Current Trends and Future Developments on (Bio-) Membranes by : Angelo Basile
Download or read book Current Trends and Future Developments on (Bio-) Membranes written by Angelo Basile and published by Elsevier. This book was released on 2023-01-31 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Trends and Future Developments on (Bio-) Membranes: Membrane Technologies in Environmental Protection and Public Health- Challenges and Opportunities illustrates the application of membrane technology used in separation processes, along with the advantages of membranes in comparison with other types of separation methods. In addition, the book illustrates new approaches for pollution monitoring and helps researchers develop new membrane systems for air or water pollution monitoring. Sections focus on the application of membrane technology to new membranes, hence it is ideal for R&D managers in industry and a variety of others, including academic researchers and postgraduate students working in strategic treatment, separation and purification processes. Includes membrane purification processes relating to environmental applications and membrane-based tools for air monitoring Discusses membrane water potabilization Presents a comprehensive reference on recent applications of membrane technology in environmental monitoring and pollution processes
Book Synopsis Recent Trends in Electronics and Communication by : Amit Dhawan
Download or read book Recent Trends in Electronics and Communication written by Amit Dhawan and published by Springer Nature. This book was released on 2021-12-13 with total page 1234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises select proceedings of the International Conference on VLSI, Communication and Signal processing (VCAS 2020). The contents are broadly divided into three topics – VLSI, Communication, and Signal Processing. The book focuses on the latest innovations, trends, and challenges encountered in the different areas of electronics and communication, especially in the area of microelectronics and VLSI design, communication systems and networks, and image and signal processing. It also offers potential solutions and provides an insight into various emerging areas such as Internet of Things (IoT), System on a Chip (SoC), Sensor Networks, underwater and underground communication networks etc. This book will be useful for academicians and professionals alike.
Book Synopsis Molecular Inclusion and Molecular Recognition - Clathrates I by : Edwin Weber
Download or read book Molecular Inclusion and Molecular Recognition - Clathrates I written by Edwin Weber and published by . This book was released on 2014-01-15 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
